Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0284 | 0.0426 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0266 | 0.0786 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0235 | 0.3279 | 0.3279 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.0789 | 0.1184 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0284 | 0.0426 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0426 | 0.0426 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0284 | 0.0603 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0284 | 0.4486 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0235 | 0.3279 | 0.3279 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0266 | 0.0786 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0204 | 0.0204 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0017 | 0.0017 |
Schistosoma mansoni | hypothetical protein | 0.0524 | 0.7683 | 0.7683 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0266 | 0.0565 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.004 | 0.0312 | 0.0091 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0037 | 0.0266 | 0.0565 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0001 | 0.0001 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0164 | 0.0164 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0023 | 0.0054 | 0.0115 |
Schistosoma mansoni | tar DNA-binding protein | 0.0457 | 0.6663 | 0.6663 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0017 | 0.0026 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0046 | 0.0404 | 0.0859 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.1894 | 0.1894 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0167 | 0.2249 | 0.2249 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0027 | 0.0112 | 0.0112 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Leishmania major | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0235 | 0.3279 | 0.3279 |
Echinococcus granulosus | dna polymerase kappa | 0.004 | 0.0312 | 0.0312 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.0633 | 0.0633 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.004 | 0.0312 | 0.0469 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0633 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.2249 | 0.2249 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0252 | 0.0252 |
Echinococcus multilocularis | dna polymerase eta | 0.004 | 0.0312 | 0.0312 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0284 | 0.0284 |
Schistosoma mansoni | tar DNA-binding protein | 0.0457 | 0.6663 | 0.6663 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0122 | 0.026 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0027 | 0.0112 | 0.0238 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0164 | 0.0246 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0266 | 0.0786 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0633 | 0.17 |
Schistosoma mansoni | tar DNA-binding protein | 0.0457 | 0.6663 | 0.6663 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0789 | 0.1184 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0056 | 0.0558 | 0.1186 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0284 | 0.5 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0266 | 0.851 |
Echinococcus granulosus | tar DNA binding protein | 0.0457 | 0.6663 | 0.6663 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0284 | 0.084 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.029 | 0.0435 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0001 | 0.0001 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0204 | 0.0204 |
Toxoplasma gondii | hypothetical protein | 0.0053 | 0.0508 | 0.8021 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0312 | 0.0664 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0048 | 0.0426 | 0.0426 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0676 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0787 | 0.118 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0204 | 0.0306 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.004 | 0.0312 | 0.0664 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0329 | 0.4706 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0266 | 0.4201 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0046 | 0.0404 | 0.0859 |
Onchocerca volvulus | 0.0038 | 0.0284 | 0.0372 | |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0284 | 0.0426 |
Trypanosoma brucei | unspecified product | 0.0028 | 0.0122 | 0.026 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.004 | 0.0312 | 0.0312 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0027 | 0.0112 | 0.0168 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0164 | 0.0164 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0329 | 0.4706 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0284 | 0.0284 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0001 | 0.0001 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0284 | 0.0426 |
Echinococcus multilocularis | dna polymerase kappa | 0.004 | 0.0312 | 0.0312 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0266 | 0.0786 |
Echinococcus granulosus | serine protein kinase ATM | 0.0027 | 0.0112 | 0.0112 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0266 | 0.0266 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0105 | 0.1293 | 0.194 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0054 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0284 | 0.0426 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0164 | 0.0164 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0122 | 0.026 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0204 | 0.0204 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0204 | 0.0306 |
Giardia lamblia | DINP protein human, muc B family | 0.004 | 0.0312 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0204 | 0.0204 |
Schistosoma mansoni | tar DNA-binding protein | 0.0457 | 0.6663 | 0.6663 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0173 | 0.2337 | 0.6528 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0284 | 0.084 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0037 | 0.0266 | 0.0786 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0235 | 0.3279 | 0.4922 |
Onchocerca volvulus | 0.0242 | 0.3381 | 1 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0457 | 0.6663 | 0.6663 |
Loa Loa (eye worm) | TAR-binding protein | 0.0457 | 0.6663 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.2518 | 0.378 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0326 | 0.0489 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0789 | 0.0789 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0284 | 0.0284 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0046 | 0.0404 | 0.0859 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.004 | 0.0312 | 0.0312 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0047 | 0.0047 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0204 | 0.0204 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0852 | 0.1279 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0284 | 0.0426 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0204 | 0.0306 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0204 | 0.0204 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0329 | 0.4706 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.004 | 0.0312 | 0.0924 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.004 | 0.0312 | 0.0664 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.002 | 0.0001 | 0.0001 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.004 | 0.0312 | 0.0091 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0266 | 0.0399 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0676 | 1 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0284 | 0.084 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.004 | 0.0312 | 0.0469 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0047 | 0.0047 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0204 | 0.0204 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.004 | 0.0312 | 0.0664 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Echinococcus multilocularis | geminin | 0.0524 | 0.7683 | 0.7683 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0105 | 0.1293 | 0.194 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.004 | 0.0312 | 0.0312 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0156 | 0.2069 | 0.4397 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0284 | 0.0426 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0284 | 0.084 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0204 | 0.0204 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0027 | 0.0112 | 0.0112 |
Loa Loa (eye worm) | RNA binding protein | 0.0457 | 0.6663 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0312 | 0.0139 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0027 | 0.0112 | 0.0238 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0156 | 0.2069 | 0.4397 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0046 | 0.0404 | 0.0859 |
Mycobacterium ulcerans | hypothetical protein | 0.0173 | 0.2337 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0289 | 0.0433 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0235 | 0.3279 | 0.3279 |
Trypanosoma brucei | unspecified product | 0.004 | 0.0312 | 0.0664 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0312 | 0.0139 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.0633 | 0.111 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0284 | 0.0426 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0048 | 0.0426 | 0.0426 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.004 | 0.0312 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0245 | 0.3429 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0266 | 0.851 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1293 | 0.194 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0266 | 0.0786 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Schistosoma mansoni | bromodomain containing protein | 0.0064 | 0.0672 | 0.0672 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0284 | 0.0603 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0212 | 0.2934 | 0.4404 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0284 | 0.0426 |
Brugia malayi | TAR-binding protein | 0.0457 | 0.6663 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0204 | 0.0306 |
Onchocerca volvulus | 0.0038 | 0.0284 | 0.0372 | |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0083 | 0.0124 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0633 | 0.0633 |
Onchocerca volvulus | 0.0097 | 0.1175 | 0.3141 | |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0156 | 0.2069 | 0.4397 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0204 | 0.0204 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.0633 | 0.1345 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0284 | 0.0426 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0167 | 0.2249 | 0.3376 |
Schistosoma mansoni | hypothetical protein | 0.0524 | 0.7683 | 0.7683 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0617 | 0.0617 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0617 | 0.0617 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0284 | 0.0284 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0037 | 0.0266 | 0.0266 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0457 | 0.6663 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0266 | 0.0786 |
Onchocerca volvulus | 0.0038 | 0.0284 | 0.0372 | |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0047 | 0.0047 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0284 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0252 | 0.0252 |
Brugia malayi | Pre-SET motif family protein | 0.0212 | 0.2934 | 0.4404 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.0633 | 0.0633 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0266 | 0.0786 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0633 | 0.17 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0266 | 0.0565 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0235 | 0.3279 | 0.3279 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0329 | 0.4706 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.004 | 0.0312 | 0.0312 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0235 | 0.3279 | 0.3279 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0312 | 0.0469 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0633 | 0.17 |
Trypanosoma brucei | glucosidase, putative | 0.0037 | 0.0266 | 0.0565 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0122 | 0.026 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0235 | 0.3279 | 0.4922 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.1894 | 0.1894 |
Echinococcus granulosus | dna polymerase eta | 0.004 | 0.0312 | 0.0312 |
Leishmania major | DNA polymerase eta, putative | 0.004 | 0.0312 | 0.0664 |
Trichomonas vaginalis | conserved hypothetical protein | 0.018 | 0.2441 | 0.722 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0457 | 0.6663 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0242 | 0.3381 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0633 | 0.0633 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.004 | 0.0312 | 0.0924 |
Brugia malayi | RNA binding protein | 0.0457 | 0.6663 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0312 | 0.0664 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.002 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0426 | 0.0639 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0266 | 0.0399 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0284 | 0.084 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0105 | 0.1293 | 0.194 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0037 | 0.0266 | 0.0266 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0426 | 0.0426 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0204 | 0.0204 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.004 | 0.0312 | 0.0312 |
Echinococcus multilocularis | tar DNA binding protein | 0.0457 | 0.6663 | 0.6663 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0235 | 0.3279 | 0.3279 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0284 | 0.0603 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0284 | 0.0426 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0284 | 0.084 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.2249 | 0.2249 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.004 | 0.0312 | 0.0469 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0312 | 0.0664 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0037 | 0.0266 | 0.0786 |
Brugia malayi | Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog | 0.0185 | 0.2518 | 0.378 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0284 | 0.0603 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0167 | 0.2249 | 0.3376 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0312 | 0.0664 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0164 | 0.2593 |
Toxoplasma gondii | FATC domain-containing protein | 0.0027 | 0.0112 | 0.1769 |
Trypanosoma brucei | unspecified product | 0.0028 | 0.0122 | 0.026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0112 | 0.0331 |
Echinococcus granulosus | geminin | 0.0524 | 0.7683 | 0.7683 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0147 | 0.0147 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0284 | 0.0426 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0112 | 0.3584 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0284 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0355 | 0.0533 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 13.5 % | Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain membrane at 10 uM | ChEMBL. | 20638843 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.