Detailed information for compound 1126264

Basic information

Technical information
  • TDR Targets ID: 1126264
  • Name: [(1R,2S,5R)-7,7-dimethyl-2-bicyclo[3.1.1]hept anyl]methanamine
  • MW: 153.265 | Formula: C10H19N
  • H donors: 1 H acceptors: 0 LogP: 2.23 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC[C@H]1CC[C@@H]2C[C@H]1C2(C)C
  • InChi: 1S/C10H19N/c1-10(2)8-4-3-7(6-11)9(10)5-8/h7-9H,3-6,11H2,1-2H3/t7-,8-,9-/m1/s1
  • InChiKey: SYJBFPCQIJQYNV-IWSPIJDZSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [(1R,2S,5R)-6,6-dimethylnorpinan-2-yl]methanamine
  • [(1R,2S,5R)-6,6-dimethyl-2-norpinanyl]methanamine
  • [(1R,2S,5R)-6,6-dimethylnorpinan-2-yl]methylamine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum replication factor C subunit 1, putative 0.002 0.0016 0.0267
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0109 0.0326 0.0337
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0025 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Schistosoma mansoni smad 0.0017 0.0006 0.0011
Brugia malayi follicle stimulating hormone receptor 0.0253 0.0825 0.082
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.004 0.0084 0.0084
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.0104 0.1392
Schistosoma mansoni acetylcholinesterase 0.0024 0.003 0.0068
Brugia malayi Carboxylesterase family protein 0.0024 0.003 0.0024
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.007 0.0064
Schistosoma mansoni opsin-like receptor 0.0025 0.0031 0.0072
Echinococcus multilocularis serotonin receptor 0.0025 0.0031 0.0029
Brugia malayi Histone deacetylase family protein 0.0039 0.0082 0.0076
Brugia malayi hypothetical protein 0.0025 0.0031 0.0026
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0172 0.0166
Loa Loa (eye worm) hypothetical protein 0.0076 0.021 0.021
Onchocerca volvulus 0.0025 0.0031 0.0745
Toxoplasma gondii thioredoxin reductase 0.0053 0.0132 0.1787
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.002 0.029
Trypanosoma brucei glucosidase, putative 0.0036 0.007 0.0173
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0185 0.0589 1
Echinococcus multilocularis nibrin 0.002 0.0016 0.0013
Echinococcus granulosus ankyrin repeat protein 0.0163 0.0514 0.0534
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0045 0.0044
Brugia malayi Carboxylesterase family protein 0.0142 0.044 0.0435
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0185 0.0589 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0025 0.0031 0.0026
Schistosoma mansoni importin beta-1 0.0061 0.016 0.0376
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.002 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.002 0.0104
Brugia malayi DKFZp564C0469 protein 0.002 0.0016 0.0011
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.003
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0253 0.0825 0.0825
Brugia malayi glutathione reductase 0.0053 0.0132 0.0127
Leishmania major cytochrome p450-like protein 0.0038 0.008 0.0199
Brugia malayi hypothetical protein 0.0019 0.0011 0.0006
Echinococcus granulosus cpg binding protein 0.0126 0.0384 0.0398
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Brugia malayi hypothetical protein 0.0024 0.003 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Loa Loa (eye worm) histone deacetylase 0.0039 0.0082 0.0082
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0132 0.0333
Loa Loa (eye worm) hypothetical protein 0.0069 0.0185 0.0185
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0039 0.0485
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Echinococcus multilocularis fmrfamide receptor 0.0025 0.0031 0.0029
Schistosoma mansoni amine GPCR 0.0025 0.0031 0.0072
Echinococcus multilocularis neuropeptide s receptor 0.0025 0.0031 0.0029
Leishmania major trypanothione reductase 0.0053 0.0132 0.0333
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0074
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0142 0.044 0.1036
Loa Loa (eye worm) MH2 domain-containing protein 0.0251 0.0819 0.0819
Loa Loa (eye worm) hypothetical protein 0.0183 0.0581 0.0581
Trichomonas vaginalis esterase, putative 0.0076 0.021 0.345
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.016 0.0404
Echinococcus multilocularis somatostatin receptor 0.0025 0.0031 0.0029
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0048 0.0046
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.0104 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0151 0.2532
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Trypanosoma brucei histone deacetylase 4 0.0039 0.0082 0.0204
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.007 0.1027
Echinococcus granulosus neuropeptide receptor A26 0.0025 0.0031 0.0029
Brugia malayi Melatonin receptor type 1A 0.0025 0.0031 0.0026
Echinococcus granulosus metabotropic glutamate receptor 5 0.0049 0.0115 0.0116
Echinococcus multilocularis neuropeptide FF receptor 2 0.0025 0.0031 0.0029
Loa Loa (eye worm) G-protein coupled receptor 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0036 0.0072 0.0072
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.008 0.008
Echinococcus multilocularis fmrfamide receptor 0.0025 0.0031 0.0029
Echinococcus multilocularis neuroligin 0.0024 0.003 0.0027
Brugia malayi G protein-coupled receptor F59B2.13 0.0025 0.0031 0.0026
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0504 0.0499
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0016 0.0035
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.0104 0.0098
Leishmania major cytochrome p450-like protein 0.0021 0.002 0.0044
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0025 0.0031 0.0072
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0074 0.0073
Entamoeba histolytica hypothetical protein 0.0109 0.0326 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0136 0.0418 0.255
Schistosoma mansoni Smad4 0.0017 0.0006 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.021 0.345
Schistosoma mansoni cpg binding protein 0.0117 0.0355 0.0834
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.002 0.0104
Loa Loa (eye worm) cytochrome P450 family protein 0.004 0.0085 0.0085
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0047 0.0114
Echinococcus granulosus acetylcholinesterase 0.0142 0.044 0.0457
Onchocerca volvulus Huntingtin homolog 0.0127 0.0389 1
Chlamydia trachomatis DNA ligase 0.002 0.0016 0.0101
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0025 0.0031 0.0072
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0136 0.0418 0.255
Brugia malayi Tachykinin-like peptides receptor 99D 0.0025 0.0031 0.0026
Wolbachia endosymbiont of Brugia malayi malonyl-CoA decarboxylase 0.2889 1 1
Echinococcus multilocularis zinc finger protein 0.0026 0.0035 0.0033
Echinococcus multilocularis cpg binding protein 0.0126 0.0384 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0485
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0016 0.0101
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.008 0.008
Echinococcus multilocularis para nitrobenzyl esterase 0.0024 0.003 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0016 0.0101
Trypanosoma brucei cytochrome P450, putative 0.0038 0.008 0.0199
Onchocerca volvulus 0.0117 0.0355 0.9108
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0047 0.0114
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.007 0.1027
Echinococcus granulosus 7tm_1 domain containing protein 0.0025 0.0031 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0016 0.0101
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0039 0.0485
Schistosoma mansoni neuropeptide receptor 0.0025 0.0031 0.0072
Loa Loa (eye worm) beta-lactamase 0.0076 0.021 0.021
Schistosoma mansoni hypothetical protein 0.0657 0.2231 0.5258
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0074 0.0073
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0151 0.0381
Echinococcus granulosus smad 0.0017 0.0006 0.0002
Echinococcus granulosus g protein coupled receptor 0.0025 0.0031 0.0029
Loa Loa (eye worm) TYRA-2 protein 0.0025 0.0031 0.0031
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.002 0.029
Schistosoma mansoni hypothetical protein 0.0065 0.0172 0.0403
Plasmodium vivax histone deacetylase, putative 0.0039 0.0082 0.1235
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0011 0.0007
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0151 0.0154
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0039 0.0485
Schistosoma mansoni smad1 5 8 and 0.0017 0.0006 0.0011
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.003 0.0068
Brugia malayi cytochrome P450 0.0021 0.002 0.0014
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0031 0.0072
Plasmodium falciparum glutathione reductase 0.0053 0.0132 0.2237
Brugia malayi G protein-coupled receptor 0.0025 0.0031 0.0026
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0019 0.0011 0.0049
Onchocerca volvulus 0.0093 0.0269 0.6892
Entamoeba histolytica hypothetical protein 0.002 0.0016 0.0483
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Brugia malayi CXXC zinc finger family protein 0.0117 0.0355 0.0349
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Brugia malayi beta-lactamase family protein 0.0076 0.021 0.0205
Schistosoma mansoni transcription factor LCR-F1 0.0109 0.0326 0.0766
Loa Loa (eye worm) RNA binding protein 0.0073 0.02 0.02
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0172 0.0176
Schistosoma mansoni biogenic amine receptor 0.0025 0.0031 0.0072
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.0031 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0485
Entamoeba histolytica hypothetical protein 0.0109 0.0326 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0011 0.002
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0031 0.0029
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0025 0.0031 0.0072
Leishmania major importin beta-1 subunit, putative 0.005 0.012 0.03
Echinococcus multilocularis histone deacetylase 6 0.0039 0.0082 0.0082
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.021 0.1273
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0136 0.0418 0.255
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0025 0.0031 0.0029
Schistosoma mansoni biogenic amine (5HT) receptor 0.0025 0.0031 0.0072
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0019 0.0011 0.0136
Onchocerca volvulus 0.0025 0.0031 0.0745
Onchocerca volvulus 0.0025 0.0031 0.0745
Schistosoma mansoni hypothetical protein 0.0898 0.3072 0.724
Leishmania major histone deacetylase, putative 0.0039 0.0082 0.0204
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0029 0.0048 0.0046
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0011 0.002
Schistosoma mansoni hypothetical protein 0.1235 0.4243 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0151 0.2532
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.007 0.0069
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.002 0.029
Mycobacterium tuberculosis Conserved protein 0.0076 0.021 0.1273
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0039 0.0485
Echinococcus granulosus replication factor c subunit 1 0.002 0.0016 0.0013
Loa Loa (eye worm) hypothetical protein 0.0076 0.021 0.021
Leishmania major cytochrome p450-like protein 0.0021 0.002 0.0044
Leishmania major C-8 sterol isomerase-like protein 0.0357 0.1189 0.3046
Echinococcus multilocularis neuropeptides capa receptor 0.0025 0.0031 0.0029
Loa Loa (eye worm) histone methyltransferase 0.0036 0.0072 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0031 0.0072
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.002 0.0044
Brugia malayi neuropeptide F receptor 0.0025 0.0031 0.0026
Loa Loa (eye worm) thioredoxin reductase 0.0053 0.0132 0.0132
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.007 0.1027
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0072
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0205 0.0659 0.0654
Echinococcus multilocularis GPCR, family 2 0.0065 0.0172 0.0176
Schistosoma mansoni myosin xvIII 0.0025 0.0031 0.0072
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.021 0.021
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.021 0.3539
Echinococcus granulosus para nitrobenzyl esterase 0.0024 0.003 0.0027
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.007 0.1027
Brugia malayi RNA binding protein 0.0073 0.02 0.0195
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0004 0.0007
Trypanosoma brucei trypanothione reductase 0.0053 0.0132 0.0333
Echinococcus multilocularis thioredoxin glutathione reductase 0.0053 0.0132 0.0135
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0504 0.0524
Schistosoma mansoni alpha glucosidase 0.0036 0.007 0.0163
Onchocerca volvulus 0.0024 0.003 0.0697
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0011 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0039 0.0485
Echinococcus multilocularis neuropeptide receptor 0.0025 0.0031 0.0029
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.008 0.0199
Echinococcus granulosus Smad4 0.0017 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0006 0.0006
Trichomonas vaginalis helicase, putative 0.0027 0.0039 0.0485
Echinococcus multilocularis acetylcholinesterase 0.0142 0.044 0.0457
Echinococcus multilocularis neuropeptide Y receptor 0.0025 0.0031 0.0029
Brugia malayi Dopamine receptor protein 2 0.0025 0.0031 0.0026
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0122 0.0371 0.2259
Mycobacterium ulcerans carboxylesterase, LipT 0.0024 0.003 0.046
Brugia malayi larval opioid receptor 0.0025 0.0031 0.0026
Trypanosoma brucei histone deacetylase, putative 0.0039 0.0082 0.0204
Schistosoma mansoni amine GPCR 0.0025 0.0031 0.0072
Loa Loa (eye worm) hypothetical protein 0.0205 0.0659 0.0659
Onchocerca volvulus 0.0024 0.003 0.0697
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.0104 0.0105
Loa Loa (eye worm) acetylcholinesterase 1 0.0142 0.044 0.044
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0074 0.1091
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.002 0.029
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0433 0.0428
Loa Loa (eye worm) hypothetical protein 0.0027 0.0041 0.0041
Brugia malayi hypothetical protein 0.0025 0.0031 0.0026
Trypanosoma cruzi importin beta-1 subunit, putative 0.005 0.012 0.03
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.008 0.132
Echinococcus multilocularis replication factor c subunit 1 0.002 0.0016 0.0013
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0006 0.0002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.021 0.0493
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.0016 0.0011
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.021 0.345
Loa Loa (eye worm) hypothetical protein 0.0076 0.021 0.021
Brugia malayi Bromodomain containing protein 0.0079 0.0222 0.0217
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.021 0.0216
Treponema pallidum DNA ligase (lig) 0.002 0.0016 1
Trypanosoma cruzi histone deacetylase, putative 0.0039 0.0082 0.0204
Leishmania major malonyl-coa decarboxylase-like protein 0.1135 0.3896 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0172 0.0172
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0025 0.0031 0.0026
Brugia malayi Cytochrome P450 family protein 0.0021 0.002 0.0014
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0172 0.0166
Brugia malayi putative neuropeptide receptor NPR1 0.0025 0.0031 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0016 0.0101
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.002 0.029
Toxoplasma gondii ATPase, AAA family protein 0.002 0.0016 0.019
Schistosoma mansoni tar DNA-binding protein 0.0073 0.02 0.047
Mycobacterium ulcerans hypothetical protein 0.0076 0.021 0.3539
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.008 0.0199
Loa Loa (eye worm) cytochrome P450 0.0021 0.002 0.002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0025 0.0031 0.0029
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0104 0.0259
Echinococcus multilocularis neuropeptide Y receptor 0.0025 0.0031 0.0029
Leishmania major GTP-binding protein, putative 0.0045 0.0104 0.0259
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0122 0.0371 0.2259
Trichomonas vaginalis ran, putative 0.0045 0.0104 0.1609
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0006 0.0002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.02 0.0641 0.0641
Schistosoma mansoni cytochrome P450 0.0021 0.002 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.002 0.029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.021 0.1273
Plasmodium falciparum glutathione reductase 0.0019 0.0011 0.0168
Onchocerca volvulus 0.0024 0.003 0.0697
Onchocerca volvulus 0.0025 0.0031 0.0745
Loa Loa (eye worm) CXXC zinc finger family protein 0.0117 0.0355 0.0355
Plasmodium falciparum thioredoxin reductase 0.0053 0.0132 0.2237
Trichomonas vaginalis hypothetical protein 0.0185 0.0589 1
Onchocerca volvulus 0.0076 0.021 0.5365
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0019 0.0011 0.0136
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2763 0.9561 1
Echinococcus granulosus tm gpcr rhodopsin 0.2763 0.9561 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0011 0.002
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.002 0.0104
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0047 0.0789
Onchocerca volvulus 0.0024 0.003 0.0697
Plasmodium vivax thioredoxin reductase, putative 0.0053 0.0132 0.2105
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0011 0.002
Mycobacterium tuberculosis Carboxylesterase LipT 0.0024 0.003 0.0165
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.021 0.0533
Schistosoma mansoni metabotropic glutamate receptor 0.0033 0.0061 0.0142
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0047 0.0632
Echinococcus granulosus neuropeptide Y receptor 0.0025 0.0031 0.0029
Echinococcus granulosus zinc finger protein 0.0026 0.0035 0.0033
Mycobacterium leprae Probable lipase LipE 0.0076 0.021 0.3383
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.02 0.0641 0.1509
Echinococcus granulosus biogenic amine 5HT receptor 0.0025 0.0031 0.0029
Brugia malayi beta-lactamase family protein 0.0076 0.021 0.0205
Onchocerca volvulus 0.0025 0.0031 0.0745
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0016
Brugia malayi Serotonin receptor 0.0025 0.0031 0.0026
Echinococcus granulosus g protein coupled receptor 0.0025 0.0031 0.0029
Schistosoma mansoni neuropeptide F-like receptor 0.0025 0.0031 0.0072
Loa Loa (eye worm) carboxylesterase 0.0142 0.044 0.044
Echinococcus granulosus allatostatin A receptor 0.0025 0.0031 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0485
Loa Loa (eye worm) hypothetical protein 0.0127 0.0389 0.0389
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.002 0.029
Loa Loa (eye worm) hypothetical protein 0.0076 0.021 0.021
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0127 0.0389 0.0389
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0485
Schistosoma mansoni cpg binding protein 0.0126 0.0384 0.0904
Echinococcus granulosus GPCR family 2 0.0065 0.0172 0.0176
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.02 0.02
Loa Loa (eye worm) carboxylesterase 0.0024 0.003 0.003
Schistosoma mansoni hypothetical protein 0.014 0.0433 0.102
Echinococcus granulosus neuropeptide Y receptor 0.0025 0.0031 0.0029
Schistosoma mansoni histone deacetylase hda2 0.0045 0.0103 0.0241
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.003 0.0068
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0025 0.0031 0.0026
Echinococcus granulosus thioredoxin glutathione reductase 0.0053 0.0132 0.0135
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0013 0.0028
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.002 0.029
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0074 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0031 0.0072
Echinococcus multilocularis neuropeptide receptor A26 0.0025 0.0031 0.0029
Onchocerca volvulus 0.0025 0.0031 0.0745
Echinococcus multilocularis histone deacetylase 7 0.0039 0.0082 0.0082
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0024 0.003 0.0328
Schistosoma mansoni histone deacetylase 4 5 0.0039 0.0082 0.0192
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0025 0.0031 0.0029
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0074 0.0068
Brugia malayi hypothetical protein 0.0025 0.0031 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.021 0.0533
Mycobacterium tuberculosis Conserved protein 0.0076 0.021 0.1273
Echinococcus granulosus histone deacetylase 7 0.0039 0.0082 0.0082
Schistosoma mansoni biogenic amine receptor 0.0025 0.0031 0.0072
Loa Loa (eye worm) histone deacetylase 7A 0.0039 0.0082 0.0082
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.002 0.029
Schistosoma mansoni amine GPCR 0.0025 0.0031 0.0072
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.002 0.0234
Brugia malayi G-protein coupled receptor 0.0025 0.0031 0.0026
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Toxoplasma gondii ABC1 family protein 0.0076 0.021 0.2858
Echinococcus multilocularis sex peptide receptor 0.0025 0.0031 0.0029
Schistosoma mansoni DNA ligase IV 0.002 0.0016 0.0037
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0039 0.0485
Loa Loa (eye worm) hypothetical protein 0.0076 0.021 0.021
Schistosoma mansoni neuropeptide receptor 0.0025 0.0031 0.0072
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0011 0.002
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0011 0.0007
Schistosoma mansoni cpg binding protein 0.0126 0.0384 0.0904
Loa Loa (eye worm) hypothetical protein 0.0049 0.0115 0.0115
Brugia malayi Cytochrome P450 family protein 0.0038 0.008 0.0074
Loa Loa (eye worm) hypothetical protein 0.0048 0.0113 0.0113
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0122 0.0371 0.2259
Brugia malayi topoisomerase 0.002 0.0016 0.0011
Echinococcus multilocularis BC026374 protein (S09 family) 0.0024 0.003 0.0027
Schistosoma mansoni BC026374 protein (S09 family) 0.0024 0.003 0.0068
Brugia malayi hypothetical protein 0.0025 0.0031 0.0026
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0016
Mycobacterium tuberculosis Conserved protein 0.0076 0.021 0.1273
Schistosoma mansoni neuropeptide F-like receptor 0.0025 0.0031 0.0072
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.0104 0.0259
Schistosoma mansoni histone deacetylase 4 5 0.0039 0.0082 0.0192
Trypanosoma cruzi histone deacetylase, putative 0.0039 0.0082 0.0204
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.0031 0.0029
Echinococcus multilocularis dro:myosuppressin receptor 0.0025 0.0031 0.0029
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0013 0.0009
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.021 0.1273
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Echinococcus granulosus neuropeptide receptor 0.0025 0.0031 0.0029
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0011 0.0023
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0103 0.0104
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.02 0.0641 0.0635
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0025 0.0031 0.0026
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0025 0.0031 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0031 0.0072
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Leishmania major hypothetical protein, conserved 0.0029 0.0047 0.0114
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Echinococcus granulosus biogenic amine 5HT receptor 0.0025 0.0031 0.0029
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.021 0.1273
Brugia malayi Metabotropic glutamate receptor precursor. 0.0039 0.0083 0.0078
Brugia malayi hypothetical protein 0.0025 0.0031 0.0026
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.02 0.0641 0.1509
Echinococcus multilocularis snurportin 1 0.0657 0.2231 0.233
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.002 0.0104
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0504 0.0524
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0065 0.0172 0.0403
Mycobacterium leprae putative cytochrome p450 0.0021 0.002 0.0056
Schistosoma mansoni smad1 5 8 and 0.0017 0.0006 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0031 0.0072
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0151 0.0354
Echinococcus multilocularis ankyrin repeat protein 0.0163 0.0514 0.0534
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0025 0.0031 0.0072
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0011 0.002
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.007 0.213
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0016 0.0101
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.002 0.0044
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.002 0.0104
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0025 0.0031 0.0072
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.0104 0.0105
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0047 0.0114
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0136 0.0418 0.7022
Brugia malayi hypothetical protein 0.0029 0.0047 0.0042
Onchocerca volvulus Neuropeptide F receptor homolog 0.0025 0.0031 0.0745
Echinococcus granulosus fmrfamide receptor 0.0025 0.0031 0.0029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.02 0.0641 0.0667
Loa Loa (eye worm) transcription factor SMAD2 0.0251 0.0819 0.0819
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0172 0.0172
Brugia malayi Importin beta-1 subunit 0.0061 0.016 0.0155
Schistosoma mansoni ran 0.0045 0.0104 0.0243
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.002 0.029
Brugia malayi Dopamine receptor 0.0025 0.0031 0.0026
Brugia malayi AKH receptor 0.0025 0.0031 0.0026
Schistosoma mansoni growth hormone secretagogue receptor 0.0025 0.0031 0.0072
Echinococcus granulosus dnaJ subfamily B 0.1235 0.4243 0.4435
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0025 0.0031 0.0029
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.021 0.3539
Plasmodium vivax importin-beta 2, putative 0.0061 0.016 0.2587
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0011 0.002
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0171 0.0175
Mycobacterium leprae Conserved hypothetical protein 0.0021 0.002 0.0056
Schistosoma mansoni hypothetical protein 0.0109 0.0326 0.0766
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0025 0.0031 0.0029
Echinococcus granulosus tar DNA binding protein 0.0073 0.02 0.0205
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.0016 0.0101
Schistosoma mansoni neuroligin 3 (S09 family) 0.0024 0.003 0.0068
Mycobacterium tuberculosis Probable reductase 0.0122 0.0371 0.2259
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.003
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0025 0.0031 0.0072
Echinococcus granulosus snurportin 1 0.0657 0.2231 0.233
Schistosoma mansoni neuropeptide receptor 0.0025 0.0031 0.0072
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0039 0.0485
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.002 0.029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0031 0.0072
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0016 0.0101
Echinococcus multilocularis G-protein coupled receptor, putative 0.0025 0.0031 0.0029
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0016 0.0035
Trypanosoma cruzi malonyl-CoA decarboxylase, mitochondrial precursor, putative 0.1135 0.3896 1
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.002 0.0017
Schistosoma mansoni amine GPCR 0.0025 0.0031 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.002 0.0104
Onchocerca volvulus 0.0025 0.0031 0.0745
Plasmodium falciparum histone deacetylase 2 0.0039 0.0082 0.1382
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.003 0.0165
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0357 0.1189 0.1184
Echinococcus multilocularis carboxylesterase 5A 0.0142 0.044 0.0457
Mycobacterium ulcerans lipase LipD 0.0076 0.021 0.3539
Brugia malayi PHD-finger family protein 0.0031 0.0053 0.0048
Schistosoma mansoni gliotactin 0.0024 0.003 0.0068
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0016
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.007 0.213
Brugia malayi hypothetical protein 0.0025 0.0031 0.0026
Plasmodium falciparum enoyl-acyl carrier reductase 0.0185 0.0589 1
Onchocerca volvulus 0.0025 0.0031 0.0745
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0163 0.0514 0.1211
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.007 0.1027
Loa Loa (eye worm) hypothetical protein 0.0357 0.1189 0.1189
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0031 0.0072
Schistosoma mansoni hypothetical protein 0.0898 0.3072 0.724
Schistosoma mansoni alpha-glucosidase 0.0138 0.0427 0.1004
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0016 0.0035
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.021 0.345
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.007 0.1027
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0249 0.0813 0.1914
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1659 0.5719 0.598
Plasmodium falciparum thioredoxin reductase 0.0019 0.0011 0.0168
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.003 0.0165
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0072
Trypanosoma cruzi histone deacetylase, putative 0.0039 0.0082 0.0204
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0025 0.0031 0.0029
Echinococcus multilocularis g-protein coupled receptor 0.0025 0.0031 0.0029
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.002 0.029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.02 0.0641 0.0667
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0036 0.007 0.0065
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Brugia malayi G-protein coupled receptor 0.0025 0.0031 0.0026
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.002 0.0104
Brugia malayi Bromodomain containing protein 0.0037 0.0075 0.007
Onchocerca volvulus 0.0025 0.0031 0.0745
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0074 0.1091
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.021 0.345
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0047 0.0613
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0031 0.0029
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.002 0.0044
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.003
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.0031 0.0029
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0045 0.0102 0.0239
Echinococcus multilocularis dnaJ subfamily B 0.1235 0.4243 0.4435
Brugia malayi GnHR receptor homolog 0.0025 0.0031 0.0026
Echinococcus multilocularis orexin receptor type 2 0.0025 0.0031 0.0029
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0011 0.0168
Onchocerca volvulus 0.0076 0.021 0.5365
Mycobacterium tuberculosis Probable dehydrogenase 0.0122 0.0371 0.2259
Loa Loa (eye worm) hypothetical protein 0.0076 0.021 0.021
Brugia malayi putative neuropeptide receptor 0.0025 0.0031 0.0026
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0171 0.0175
Echinococcus multilocularis geminin 0.0898 0.3072 0.321
Echinococcus granulosus neuropeptides capa receptor 0.0025 0.0031 0.0029
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.002 0.029
Echinococcus multilocularis neuropeptides capa receptor 0.0025 0.0031 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0031 0.0072
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.021 0.0216
Toxoplasma gondii histone deacetylase HDAC1 0.0039 0.0082 0.1094
Brugia malayi hypothetical protein 0.0025 0.0031 0.0026
Schistosoma mansoni adenoreceptor 0.0025 0.0031 0.0072
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.003 0.0068
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0074 0.6781
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Schistosoma mansoni neuropeptide receptor 0.0025 0.0031 0.0072
Brugia malayi Carboxylesterase family protein 0.0142 0.044 0.0435
Echinococcus granulosus g protein coupled receptor 0.0025 0.0031 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0485
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.007 0.1027
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0036 0.0072 0.0072
Brugia malayi Carboxylesterase family protein 0.0024 0.003 0.0024
Echinococcus granulosus acetylcholinesterase 0.0142 0.044 0.0457
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Schistosoma mansoni topbp1 0.002 0.0016 0.0037
Trypanosoma brucei C-8 sterol isomerase, putative 0.0357 0.1189 0.3046
Plasmodium vivax histone deacetylase 2, putative 0.0039 0.0082 0.1235
Brugia malayi MH2 domain containing protein 0.0251 0.0819 0.0814
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0074 0.0182
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.002 0.0016 0.0235
Loa Loa (eye worm) hypothetical protein 0.0061 0.016 0.016
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0657 0.2231 0.2231
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.003
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.002 0.0104
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0011 0.002
Brugia malayi sulfakinin receptor protein 0.0025 0.0031 0.0026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0011 0.002
Echinococcus multilocularis importin subunit beta 1 0.0061 0.016 0.0164
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.002 0.0104
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0025 0.0031 0.0029
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0025 0.0031 0.0026
Onchocerca volvulus 0.0025 0.0031 0.0745
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0504 0.0524
Schistosoma mansoni opsin-like receptor 0.0025 0.0031 0.0072
Echinococcus granulosus importin subunit beta 1 0.0061 0.016 0.0164
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Schistosoma mansoni ran 0.0045 0.0104 0.0243
Brugia malayi hypothetical protein 0.0025 0.0031 0.0026
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0074 0.0182
Echinococcus granulosus nibrin 0.002 0.0016 0.0013
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.012 0.1887
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.021 0.345
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0074 0.0172
Brugia malayi hypothetical protein 0.0127 0.0389 0.0384
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0025 0.0031 0.0745
Echinococcus granulosus neuropeptide FF receptor 2 0.0025 0.0031 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0025 0.0031 0.0031
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0067 0.0067
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0074 0.0182
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0024 0.003 0.0027
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0016
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0006 0.0002
Brugia malayi hypothetical protein 0.0109 0.0326 0.032
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0025 0.0031 0.0029
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0025 0.0031 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.002 0.029
Onchocerca volvulus Huntingtin homolog 0.0127 0.0389 1
Echinococcus multilocularis histone deacetylase 0.0039 0.0082 0.0082
Brugia malayi neuropeptide F receptor 0.0025 0.0031 0.0026
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.002 0.0104
Echinococcus granulosus neuropeptides capa receptor 0.0025 0.0031 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0016 0.0101
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0151 0.0911
Loa Loa (eye worm) hypothetical protein 0.0033 0.0062 0.0062
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0011 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0485
Trypanosoma cruzi malonyl-CoA decarboxylase, mitochondrial precursor, putative 0.1135 0.3896 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0025 0.0031 0.0029
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.016 0.2171
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.0016 0.0037
Loa Loa (eye worm) hypothetical protein 0.0142 0.044 0.044
Onchocerca volvulus 0.0024 0.003 0.0697
Trypanosoma brucei malonyl-CoA decarboxylase, mitochondrial precursor, putative 0.1135 0.3896 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.002 0.029
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0185 0.0589 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.003
Echinococcus granulosus 7TM GPCR rhodopsin 0.0025 0.0031 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0025 0.0031 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.002 0.0104
Entamoeba histolytica hypothetical protein 0.0109 0.0326 1
Brugia malayi hypothetical protein 0.002 0.0016 0.0011
Schistosoma mansoni biogenic amine (5HT) receptor 0.0025 0.0031 0.0072
Echinococcus granulosus dro:myosuppressin receptor 0.0025 0.0031 0.0029
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0031 0.0072
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0039 0.0485
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.02 0.0641 0.0667
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0504 0.0504
Schistosoma mansoni neuropeptide f receptor 76f 0.0025 0.0031 0.0072
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0072
Echinococcus granulosus histone deacetylase 0.0039 0.0082 0.0082
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0484 0.1632 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0025 0.0031 0.0029
Brugia malayi TAR-binding protein 0.0073 0.02 0.0195
Echinococcus multilocularis histone deacetylase 6 0.0039 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0021 0.002 0.0045
Loa Loa (eye worm) hypothetical protein 0.014 0.0433 0.0433
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0031 0.0072
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0024 0.003 0.0027
Plasmodium falciparum importin beta, putative 0.0061 0.016 0.2711
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0025 0.0031 0.0029
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0016 0.0016
Echinococcus granulosus mixed lineage leukemia protein mll 0.0029 0.0048 0.0046
Trichomonas vaginalis importin beta-1, putative 0.005 0.012 0.1887
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0074 0.0073
Onchocerca volvulus 0.0025 0.0031 0.0745
Brugia malayi Thioredoxin reductase 0.0053 0.0132 0.0127
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0011 0.002
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0025 0.0031 0.0031
Loa Loa (eye worm) glutathione reductase 0.0053 0.0132 0.0132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.007 0.0928
Echinococcus multilocularis tar DNA binding protein 0.0073 0.02 0.0205
Echinococcus multilocularis transient receptor potential cation channel 0.0167 0.0527 0.0548
Schistosoma mansoni amine GPCR 0.0025 0.0031 0.0072
Onchocerca volvulus 0.0025 0.0031 0.0745
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0074 0.0073
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0013 0.0009
Echinococcus multilocularis serotonin receptor 0.0025 0.0031 0.0029
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.002 0.0104
Trypanosoma cruzi FHA domain containing protein, putative 0.002 0.0016 0.0035
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0011 0.011
Entamoeba histolytica Ran family GTPase 0.0045 0.0104 0.3164
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0025 0.0031 0.0031
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0074 0.0172
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.021 0.0493
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0049 0.0115 0.0116
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0025 0.0031 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0151 0.0354
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0185 0.0589 0.3596
Schistosoma mansoni smad1 5 8 and 0.0017 0.0006 0.0011
Brugia malayi RE15519p 0.0025 0.0031 0.0026
Trypanosoma brucei histone deacetylase 3 0.0039 0.0082 0.0204
Brugia malayi hypothetical protein 0.0025 0.0031 0.0026
Brugia malayi hypothetical protein 0.0025 0.0031 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0073 0.02 0.047
Onchocerca volvulus 0.002 0.0016 0.0357
Loa Loa (eye worm) hypothetical protein 0.2889 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Echinococcus granulosus histone deacetylase 6 0.0039 0.0082 0.0082
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0025 0.0031 0.0029
Echinococcus granulosus g-protein coupled receptor 0.0025 0.0031 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.002 0.0104
Brugia malayi metabotropic glutamate receptor type 2 0.0019 0.0013 0.0007
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0025 0.0031 0.0029
Onchocerca volvulus 0.0025 0.0031 0.0745
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.0104 0.175
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0011 0.002
Plasmodium falciparum histone deacetylase, putative 0.0039 0.0082 0.1382
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0016 0.0035
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0151 0.2045
Loa Loa (eye worm) Smad1 0.0017 0.0006 0.0006
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.021 0.1273
Echinococcus granulosus G protein coupled receptor 139 0.0025 0.0031 0.0029
Echinococcus granulosus sex peptide receptor 0.0025 0.0031 0.0029
Loa Loa (eye worm) G-protein coupled receptor 0.0025 0.0031 0.0031
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.007 0.1027
Brugia malayi Cytochrome P450 family protein 0.0038 0.008 0.0074
Echinococcus granulosus neuropeptide s receptor 0.0025 0.0031 0.0029
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0109 0.0326 0.0337
Echinococcus multilocularis 0.0021 0.002 0.0017
Leishmania major histone deacetylase, putative 0.0039 0.0082 0.0204
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0031 0.0029
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0067 0.0067
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.002 0.0104
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0011 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0073 0.02 0.047
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0151 0.2532
Echinococcus multilocularis G protein coupled receptor 139 0.0025 0.0031 0.0029
Echinococcus granulosus neuroligin 0.0024 0.003 0.0027
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0016
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0011 0.002
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.002 0.029
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0025 0.0031 0.0029
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0004 0.0007
Echinococcus granulosus histone deacetylase 6 0.0039 0.0082 0.0082
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.002 0.029
Brugia malayi Calcitonin receptor-like protein seb-1 0.0205 0.0659 0.0654
Onchocerca volvulus 0.0025 0.0031 0.0745
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.002 0.0016 0.019
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.002 0.0104
Echinococcus multilocularis neuropeptide receptor 0.0025 0.0031 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.007 0.0173
Trichomonas vaginalis spcc417.12 protein, putative 0.0024 0.003 0.0328
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.0016 0.0483
Brugia malayi hypothetical protein 0.002 0.0016 0.0011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0045 0.0044
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0031 0.0072
Echinococcus granulosus metabotropic glutamate receptor 2 0.0033 0.0061 0.006
Brugia malayi Dopamine receptor protein 1 0.0025 0.0031 0.0026
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.0104 0.1609
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.007 0.0173
Schistosoma mansoni biogenic amine receptor 0.0025 0.0031 0.0072
Schistosoma mansoni histamine h1 receptor 0.0025 0.0031 0.0072
Loa Loa (eye worm) neuropeptide F receptor 0.0025 0.0031 0.0031
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Echinococcus multilocularis acetylcholinesterase 0.0142 0.044 0.0457
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0016 0.0101
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0122 0.0371 0.6193
Schistosoma mansoni tar DNA-binding protein 0.0073 0.02 0.047
Schistosoma mansoni opsin-like receptor 0.0025 0.0031 0.0072
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0025 0.0031 0.0029
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0019 0.0011 0.0136
Onchocerca volvulus 0.0025 0.0031 0.0745
Schistosoma mansoni hypothetical protein 0.0065 0.0172 0.0403
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.021 0.0205
Loa Loa (eye worm) CYP4Cod1 0.0038 0.008 0.008
Loa Loa (eye worm) melatonin receptor type 1A 0.0025 0.0031 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.02 0.0641 0.0667
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0073 0.02 0.047
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.002 0.0044
Plasmodium vivax glutathione reductase, putative 0.0053 0.0132 0.2105
Giardia lamblia Replication factor C, subunit 1 0.002 0.0016 0.0626
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0074 0.0073
Plasmodium vivax replication factor C subunit 1, putative 0.002 0.0016 0.0101
Brugia malayi Serotonin receptor 0.0025 0.0031 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.002 0.0104
Onchocerca volvulus 0.0076 0.021 0.5365
Echinococcus granulosus alpha 1A adrenergic receptor 0.0025 0.0031 0.0029
Brugia malayi Histone deacetylase family protein 0.0039 0.0082 0.0076
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0072
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.002 0.0016 0.0006
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0011 0.002
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0074 0.0182
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0205 0.0659 0.0659
Echinococcus granulosus histone deacetylase 6 0.0045 0.0103 0.0104
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.0016 0.0011
Echinococcus granulosus geminin 0.0898 0.3072 0.321
Loa Loa (eye worm) hypothetical protein 0.0037 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0142 0.044 0.044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.02 0.0641 0.1509
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.012 0.1887
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0485
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0185 0.0589 1
Brugia malayi F/Y-rich N-terminus family protein 0.0038 0.0077 0.0072
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0185 0.0589 0.8076
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.007 0.1027
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.002 0.029
Brugia malayi ORL1-like opioid receptor 0.0025 0.0031 0.0026
Brugia malayi Cytochrome P450 family protein 0.004 0.0085 0.008
Onchocerca volvulus 0.0025 0.0031 0.0745
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.002 0.0104
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.021 0.1273
Echinococcus granulosus transient receptor potential cation channel 0.0167 0.0526 0.0547
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0053 0.0132 0.0796
Schistosoma mansoni alpha-glucosidase 0.0138 0.0427 0.1004
Mycobacterium ulcerans beta-lactamase 0.0076 0.021 0.3539
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Toxoplasma gondii histone lysine methyltransferase SET1 0.0225 0.0728 1
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0185 0.0589 0.0579
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.002 0.0104
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.002 0.0104
Loa Loa (eye worm) neuropeptide F receptor 0.0025 0.0031 0.0031
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0122 0.0371 0.2259
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0172 0.0176
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0172 0.0176
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.002 0.029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0104 0.0259
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0025 0.0031 0.0031
Echinococcus multilocularis smad 0.0017 0.0006 0.0002
Echinococcus multilocularis allatostatin A receptor 0.0025 0.0031 0.0029
Echinococcus granulosus peptide allatostatin:somatostatin 0.0025 0.0031 0.0029
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0172 0.0176
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0031
Echinococcus granulosus serotonin receptor 0.0025 0.0031 0.0029
Echinococcus granulosus tachykinin peptides receptor 99D 0.0025 0.0031 0.0029
Schistosoma mansoni bromodomain containing protein 0.0068 0.0183 0.043
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0151 0.0154
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0045 0.0105
Schistosoma mansoni topbp1 0.002 0.0016 0.0037
Mycobacterium leprae conserved hypothetical protein 0.0076 0.021 0.3383
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0013 0.0028
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0074 0.1091
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0048 0.011
Echinococcus granulosus BC026374 protein S09 family 0.0024 0.003 0.0027
Loa Loa (eye worm) TAR-binding protein 0.0073 0.02 0.02
Schistosoma mansoni zinc finger protein 0.0026 0.0035 0.0082
Echinococcus granulosus carboxylesterase 5A 0.0142 0.044 0.0457
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0011 0.011
Schistosoma mansoni hypothetical protein 0.0065 0.0172 0.0403
Echinococcus granulosus neuropeptide receptor 0.0025 0.0031 0.0029
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0011 0.0168
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.002 0.0104
Entamoeba histolytica hypothetical protein 0.005 0.012 0.3657
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0031 0.0072
Loa Loa (eye worm) carboxylesterase 0.0024 0.003 0.003
Echinococcus granulosus somatostatin receptor 0.0025 0.0031 0.0029
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0047 0.0789
Brugia malayi Carboxylesterase family protein 0.0024 0.003 0.0024
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.016 0.0404
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.007 0.0069
Onchocerca volvulus 0.0025 0.0031 0.0745
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0485
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.02 0.0195
Brugia malayi Carboxylesterase family protein 0.0024 0.003 0.0024
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0016 0.0101
Leishmania major hypothetical protein, conserved 0.0076 0.021 0.0533
Schistosoma mansoni alpha-1 adrenergic receptor 0.0025 0.0031 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0074 0.2243
Plasmodium vivax hypothetical protein, conserved 0.0076 0.021 0.345
Brugia malayi beta-lactamase 0.0076 0.021 0.0205
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.021 0.1273
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0033 0.0061 0.006
Schistosoma mansoni metabotropic glutamate receptor 0.0019 0.0013 0.0029
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.007 0.0173
Echinococcus granulosus orexin receptor type 2 0.0025 0.0031 0.0029
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.002 0.029
Schistosoma mansoni hypothetical protein 0.002 0.0016 0.0035
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0357 0.1189 0.3046
Echinococcus granulosus hypothetical protein 0.0025 0.0031 0.0029
Loa Loa (eye worm) glutamate receptor 0.0039 0.0083 0.0083
Echinococcus multilocularis Smad4 0.0017 0.0006 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.021 0.0533
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.0104 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0485
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.0047
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0025 0.0031 0.0072
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0048 0.0046
Brugia malayi RNA, U transporter 1 0.0175 0.0555 0.0549
Entamoeba histolytica hypothetical protein 0.0109 0.0326 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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