Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.5907 | 0.5907 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.5907 | 0.5907 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.5907 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.3823 | 0.3823 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.5907 | 1 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.3823 | 0.3823 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.3823 | 0.3823 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3823 | 0.6472 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.3823 | 0.3823 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.3823 | 0.3823 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.3823 | 0.3823 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3823 | 0.6472 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.3823 | 0.3823 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.5907 | 0.5907 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 1 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.5907 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3823 | 0.6472 |
Brugia malayi | RNA binding protein | 0.0062 | 0.3823 | 0.3823 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.5907 | 0.5907 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0 | 0.5 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.5907 | 0.5907 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3823 | 0.6472 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3823 | 0.6472 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.5907 | 0.5907 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.