Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0083 | 0.0434 | 0.0761 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0123 | 0.0804 | 0.2758 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0071 | 0.0328 | 0.1415 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0123 | 0.0804 | 0.5 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0811 | 0.7049 | 0.8896 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0142 | 0.0972 | 0.6386 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0064 | 0.0268 | 0.0918 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.009 | 0.0498 | 0.0095 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0123 | 0.0804 | 0.123 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0123 | 0.0804 | 0.2758 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0123 | 0.0804 | 0.2758 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0071 | 0.0328 | 0.1127 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0105 | 0.0641 | 0.2202 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0112 | 0.07 | 0.1228 |
Echinococcus granulosus | tumor protein p63 | 0.0398 | 0.3304 | 0.5596 |
Echinococcus multilocularis | dna polymerase kappa | 0.0113 | 0.0712 | 0.1018 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0096 | 0.0096 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0123 | 0.0804 | 0.2758 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0123 | 0.0804 | 0.2758 |
Leishmania major | DNA polymerase eta, putative | 0.0055 | 0.0188 | 0.0646 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0096 | 0.0096 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0901 | 0.7871 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0811 | 0.7049 | 0.8896 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0811 | 0.7049 | 0.8896 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0811 | 0.7049 | 0.8896 |
Plasmodium falciparum | glutathione reductase | 0.0355 | 0.2913 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0355 | 0.2913 | 0.5108 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0096 | 0.0168 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0082 | 0.0427 | 0.1842 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0548 | 0.0961 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0082 | 0.0427 | 0.0427 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0123 | 0.0804 | 0.123 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0096 | 0.0162 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0113 | 0.0712 | 0.109 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.009 | 0.0498 | 0.1709 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0068 | 0.0232 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0057 | 0.02 | 0.0687 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0123 | 0.0804 | 0.2758 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0096 | 0.0162 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0095 | 0.0548 | 0.0548 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.009 | 0.0498 | 0.1709 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0142 | 0.0973 | 0.3341 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0358 | 0.2932 | 0.4193 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Echinococcus multilocularis | tumor protein p63 | 0.0398 | 0.3304 | 0.4724 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.03 | 0.2407 | 0.8263 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0096 | 0.0137 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0805 | 0.6994 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0754 | 0.6535 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0113 | 0.0712 | 0.2444 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0123 | 0.0804 | 0.2758 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0685 | 0.5905 | 0.5905 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0092 | 0.0516 | 0.0874 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0123 | 0.0804 | 0.2758 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0355 | 0.2913 | 0.334 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0142 | 0.0973 | 0.3341 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0811 | 0.7049 | 0.8809 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0901 | 0.7871 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.009 | 0.0507 | 0.0888 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0123 | 0.0804 | 0.2249 |
Brugia malayi | glutathione reductase | 0.0355 | 0.2913 | 0.5108 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0113 | 0.0712 | 0.2444 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2319 | 0.3549 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2319 | 0.3549 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0811 | 0.7049 | 0.8896 |
Echinococcus multilocularis | geminin | 0.0168 | 0.1212 | 0.1733 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0082 | 0.0427 | 0.0749 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.03 | 0.2407 | 0.8263 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1212 | 0.1212 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0068 | 0.0232 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0083 | 0.0434 | 0.0735 |
Onchocerca volvulus | 0.0754 | 0.6535 | 1 | |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0123 | 0.0804 | 0.1678 |
Schistosoma mansoni | DNA polymerase eta | 0.0112 | 0.07 | 0.07 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0083 | 0.0434 | 0.0621 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.029 | 0.2319 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.009 | 0.0498 | 0.1709 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0123 | 0.0804 | 0.2758 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0082 | 0.0427 | 0.0427 |
Trypanosoma brucei | unspecified product | 0.0056 | 0.0197 | 0.0676 |
Echinococcus granulosus | expressed protein | 0.0073 | 0.0344 | 0.0582 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2319 | 0.3549 |
Plasmodium falciparum | glutathione reductase | 0.0123 | 0.0804 | 0.2758 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2319 | 0.3549 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0064 | 0.0268 | 0.0918 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0123 | 0.0804 | 0.1149 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0123 | 0.0804 | 0.1409 |
Plasmodium vivax | glutathione reductase, putative | 0.0355 | 0.2913 | 1 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0071 | 0.0328 | 0.1127 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Mycobacterium ulcerans | hypothetical protein | 0.0158 | 0.1119 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0663 | 0.5703 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0123 | 0.0804 | 0.2758 |
Leishmania major | mitochondrial DNA polymerase beta | 0.03 | 0.2407 | 0.8263 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0355 | 0.2913 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0123 | 0.0804 | 0.2758 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0124 | 0.0425 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0434 | 0.0761 |
Schistosoma mansoni | rotamase | 0.0073 | 0.0344 | 0.0344 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0095 | 0.0548 | 0.0928 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0.0344 | 0.0526 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0113 | 0.0712 | 0.109 |
Trypanosoma brucei | trypanothione reductase | 0.0355 | 0.2913 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Onchocerca volvulus | 0.0095 | 0.0548 | 0.0528 | |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0123 | 0.0804 | 0.0506 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2319 | 0.3549 |
Echinococcus granulosus | geminin | 0.0168 | 0.1212 | 0.2053 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0095 | 0.0548 | 0.0548 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0096 | 0.0168 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0123 | 0.0804 | 0.2758 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0123 | 0.0804 | 0.2758 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0096 | 0.0137 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.03 | 0.2407 | 0.8263 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0151 | 0.052 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.009 | 0.0507 | 0.0888 |
Trichomonas vaginalis | rotamase, putative | 0.0073 | 0.0344 | 0.0526 |
Brugia malayi | polk-prov protein | 0.0057 | 0.02 | 0.0351 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0057 | 0.02 | 0.0687 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0073 | 0.0344 | 0.0603 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1212 | 0.1212 |
Echinococcus granulosus | dna polymerase eta | 0.0112 | 0.07 | 0.1186 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0811 | 0.7049 | 0.8896 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0082 | 0.0427 | 0.0749 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0083 | 0.0434 | 0.0434 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.0761 | 0.1334 |
Plasmodium vivax | SET domain protein, putative | 0.0095 | 0.0548 | 0.1881 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0123 | 0.0804 | 0.2758 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0123 | 0.0804 | 0.5 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0123 | 0.0804 | 0.2758 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0071 | 0.0328 | 0.1127 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0123 | 0.0804 | 0.2758 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.0761 | 0.1334 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0082 | 0.0427 | 0.0724 |
Plasmodium falciparum | thioredoxin reductase | 0.0123 | 0.0804 | 0.2758 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0685 | 0.5905 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0071 | 0.0328 | 0.1127 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0123 | 0.0804 | 0.2758 |
Brugia malayi | Pre-SET motif family protein | 0.0663 | 0.5703 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0112 | 0.07 | 0.2403 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.029 | 0.2319 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0355 | 0.2913 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0095 | 0.0548 | 0.0548 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0123 | 0.0804 | 0.2249 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.02 | 0.0351 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0123 | 0.0804 | 0.1361 |
Leishmania major | DNA polymerase eta, putative | 0.0112 | 0.07 | 0.2403 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0901 | 0.7871 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0355 | 0.2913 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0123 | 0.0804 | 0.5 |
Trypanosoma brucei | unspecified product | 0.0105 | 0.0641 | 0.2202 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0123 | 0.0804 | 0.2758 |
Trichomonas vaginalis | rotamase, putative | 0.0071 | 0.0328 | 0.0502 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.029 | 0.2319 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0123 | 0.0804 | 0.2758 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2319 | 0.3549 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0123 | 0.0804 | 0.2758 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0068 | 0.0232 |
Echinococcus granulosus | dna polymerase kappa | 0.0113 | 0.0712 | 0.1206 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0123 | 0.0804 | 0.2249 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0123 | 0.0804 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0215 | 0.0376 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0123 | 0.0804 | 0.2758 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0901 | 0.7871 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0058 | 0.0215 | 0.0215 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0142 | 0.0972 | 0.0732 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2319 | 0.3549 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.0761 | 0.1334 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0112 | 0.07 | 0.2403 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0073 | 0.0344 | 0.0603 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0071 | 0.0328 | 0.1127 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0064 | 0.0268 | 0.0918 |
Loa Loa (eye worm) | glutathione reductase | 0.0355 | 0.2913 | 0.5108 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0095 | 0.0548 | 0.0548 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0055 | 0.0188 | 0.0646 |
Toxoplasma gondii | thioredoxin reductase | 0.0355 | 0.2913 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0095 | 0.0548 | 0.0961 |
Echinococcus multilocularis | expressed protein | 0.0073 | 0.0344 | 0.0491 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.029 | 0.2319 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0095 | 0.0548 | 0.0784 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0358 | 0.2932 | 0.4966 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0082 | 0.0427 | 0.0611 |
Echinococcus multilocularis | dna polymerase eta | 0.0112 | 0.07 | 0.1001 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0096 | 0.0096 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0355 | 0.2913 | 0.5108 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0123 | 0.0804 | 0.2758 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0158 | 0.1119 | 0.0929 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2319 | 0.3549 |
Leishmania major | trypanothione reductase | 0.0355 | 0.2913 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0095 | 0.0548 | 0.1881 |
Onchocerca volvulus | 0.0083 | 0.0434 | 0.0348 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0113 | 0.0712 | 0.2444 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.07 | 0.1228 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0055 | 0.0188 | 0.0646 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0123 | 0.0804 | 0.2758 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0095 | 0.0548 | 0.0784 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0142 | 0.0973 | 0.3341 |
Trypanosoma brucei | unspecified product | 0.0056 | 0.0197 | 0.0676 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0685 | 0.5905 | 0.8443 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0068 | 0.0232 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.