Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0034 | 0.0027 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0096 | 0.0103 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0308 | 0.248 | 0.2579 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.0296 | 0.0301 |
Onchocerca volvulus | 0.0048 | 0.0345 | 0.2148 | |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0145 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0659 | 0.0679 |
Loa Loa (eye worm) | carboxylesterase | 0.0199 | 0.158 | 0.1641 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0145 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0096 | 0.0092 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0086 | 0.0659 | 0.0709 |
Mycobacterium ulcerans | oxidoreductase | 0.0086 | 0.0659 | 0.0652 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0034 | 0.0027 |
Onchocerca volvulus | 0.0036 | 0.0245 | 0.1512 | |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0034 | 0.0027 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0034 | 0.0166 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0034 | 0.0027 |
Brugia malayi | Mitochondrial import inner membrane translocase subunit Tim17 family protein | 0.004 | 0.0282 | 0.0287 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0245 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0034 | 0.0027 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0245 | 0.0264 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0245 | 0.3649 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0245 | 0.0238 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0007 | 0.0008 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0034 | 0.0027 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0245 | 0.0248 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0008 | 0.0002 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.0031 | 0.0152 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.0018 | 0.001 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase AldC | 0.0007 | 0.0008 | 0.0008 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0145 | 0.2109 |
Schistosoma mansoni | amine oxidase | 0.0086 | 0.0659 | 0.0679 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.0018 | 0.001 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0096 | 0.1351 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0034 | 0.0027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0031 | 0.0152 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0086 | 0.0659 | 1 |
Echinococcus multilocularis | 0.0086 | 0.0659 | 0.0679 | |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0245 | 0.0248 |
Schistosoma mansoni | smad | 0.0008 | 0.0018 | 0.001 |
Loa Loa (eye worm) | carboxylesterase | 0.1176 | 0.9593 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.1176 | 0.9593 | 1 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0007 | 0.0008 | 0.0005 |
Echinococcus granulosus | death domain containing protein | 0.0032 | 0.021 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0025 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0034 | 0.0027 |
Echinococcus granulosus | replication factor c subunit 1 | 0.001 | 0.0031 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0245 | 0.0248 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.0296 | 0.0301 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.014 | 0.1101 | 0.1141 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.021 | 0.0211 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0034 | 0.0027 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0145 | 0.1835 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0031 | 0.0152 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0245 | 0.0264 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0145 | 0.0137 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0034 | 0.0027 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0199 | 0.158 | 0.1701 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0688 | 0.5593 | 0.5827 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0125 | 0.0978 | 0.0972 |
Onchocerca volvulus | 0.0199 | 0.158 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0245 | 0.0248 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.014 | 0.1101 | 0.1141 |
Mycobacterium tuberculosis | Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde | 0.0007 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0245 | 0.0248 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.0296 | 0.0301 |
Echinococcus multilocularis | smad | 0.0008 | 0.0018 | 0.001 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0032 | 0.0211 | 0.0212 |
Entamoeba histolytica | hypothetical protein | 0.001 | 0.0031 | 0.032 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0282 | 0.0287 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0007 | 0.0008 | 0.0004 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.0018 | 0.001 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0236 | 0.1884 | 0.1958 |
Brugia malayi | SWIRM domain containing protein | 0.0086 | 0.0659 | 0.0679 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0007 | 0.0008 | 0.0004 |
Echinococcus granulosus | expressed conserved protein | 0.0092 | 0.0707 | 0.073 |
Echinococcus granulosus | expressed protein | 0.0048 | 0.0341 | 0.0348 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0296 | 0.0301 |
Brugia malayi | Uncoordinated protein 44 | 0.0032 | 0.021 | 0.0211 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0145 | 0.1414 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0032 | 0.021 | 0.0211 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0245 | 0.0238 |
Toxoplasma gondii | mitochondrial inner membrane translocase subunit TIM17, putative | 0.004 | 0.0282 | 0.2831 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.158 | 0.1641 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.001 | 0.0031 | 0.0152 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.0008 | 0.0006 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.0008 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0096 | 0.0092 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.001 | 0.0031 | 0.0025 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0088 | 0.0095 |
Brugia malayi | hypothetical protein | 0.0199 | 0.158 | 0.1641 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0096 | 0.0092 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0145 | 0.1414 |
Onchocerca volvulus | 0.0199 | 0.158 | 1 | |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0031 | 0.0152 |
Onchocerca volvulus | 0.0007 | 0.0008 | 0.0002 | |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.001 | 0.0031 | 0.0025 |
Brugia malayi | Carboxylesterase family protein | 0.0199 | 0.158 | 0.1641 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0284 | 0.0288 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.021 | 0.0211 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0145 | 0.0137 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0008 | 0.0009 |
Plasmodium falciparum | mitochondrial import inner membrane translocase subunit TIM10, putative | 0.0048 | 0.0341 | 0.5124 |
Schistosoma mansoni | topbp1 | 0.001 | 0.0031 | 0.0025 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0086 | 0.0659 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0086 | 0.0659 | 1 |
Echinococcus multilocularis | expressed protein | 0.0048 | 0.0341 | 0.0348 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.0018 | 0.001 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0199 | 0.158 | 0.1641 |
Loa Loa (eye worm) | carboxylesterase | 0.0199 | 0.158 | 0.1641 |
Echinococcus multilocularis | neuroligin | 0.0199 | 0.158 | 0.1641 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0034 | 0.0027 |
Onchocerca volvulus | 0.0199 | 0.158 | 1 | |
Onchocerca volvulus | 0.0036 | 0.0245 | 0.1512 | |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.0018 | 0.001 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0245 | 0.0238 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0125 | 0.0978 | 0.1013 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0086 | 0.0659 | 1 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0007 | 0.0008 | 0.0009 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.1226 | 1 | 1 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0007 | 0.0008 | 0.0016 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0032 | 0.021 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.158 | 0.1641 |
Onchocerca volvulus | 0.0086 | 0.0659 | 0.414 | |
Plasmodium vivax | mitochondrial import inner membrane translocase subunit TIM10, putative | 0.0048 | 0.0341 | 0.5124 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.158 | 0.1641 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0245 | 0.0248 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0345 | 0.0352 |
Plasmodium vivax | hypothetical protein, conserved | 0.0086 | 0.0659 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0034 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0245 | 0.0248 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.0018 | 0.001 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0145 | 0.0143 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0086 | 0.0659 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0034 | 0.0027 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0018 | 0.001 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0245 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0659 | 0.0679 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0034 | 0.0027 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0245 | 0.0238 |
Brugia malayi | hypothetical protein | 0.0036 | 0.025 | 0.0253 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0245 | 0.0238 |
Plasmodium vivax | mitochondrial import inner membrane translocase subunit TIM23, putative | 0.004 | 0.0282 | 0.4218 |
Mycobacterium ulcerans | monoamine oxidase | 0.0086 | 0.0659 | 0.0652 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0282 | 0.0287 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0018 | 0.001 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0245 | 0.0248 |
Giardia lamblia | Replication factor C, subunit 1 | 0.001 | 0.0031 | 1 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0007 | 0.0008 | 0.0009 |
Mycobacterium tuberculosis | Probable pyrroline-5-carboxylate dehydrogenase RocA | 0.0007 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0659 | 0.0679 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0098 | 0.0756 | 0.0781 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0199 | 0.158 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0034 | 0.0027 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0034 | 0.0027 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0245 | 0.0264 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0145 | 0.0156 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0245 | 0.0264 |
Echinococcus granulosus | nibrin | 0.001 | 0.0031 | 0.0025 |
Schistosoma mansoni | amine oxidase | 0.0086 | 0.0659 | 0.0679 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0034 | 0.0027 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.0031 | 0.0152 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0199 | 0.158 | 0.1641 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0034 | 0.0027 |
Onchocerca volvulus | 0.0199 | 0.158 | 1 | |
Echinococcus granulosus | neuroligin | 0.0199 | 0.158 | 0.1641 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0034 | 0.0027 |
Brugia malayi | Protein kinase domain containing protein | 0.0032 | 0.021 | 0.0211 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0086 | 0.0659 | 0.0679 |
Onchocerca volvulus | 0.0007 | 0.0008 | 0.0002 | |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0245 | 0.0264 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0236 | 0.1884 | 0.1958 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.1139 | 0.9292 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0034 | 0.0027 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0245 | 0.1512 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.001 | 0.0031 | 0.032 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0245 | 0.3652 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0032 | 0.021 | 0.0211 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0034 | 0.0027 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0007 | 0.0008 | 0.0004 |
Mycobacterium ulcerans | dehydrogenase | 0.0086 | 0.0659 | 0.0652 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0245 | 0.1512 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0098 | 0.0756 | 0.0781 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0086 | 0.0659 | 0.0679 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0355 | 0.0363 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0034 | 0.0027 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0199 | 0.158 | 0.1641 |
Plasmodium falciparum | mitochondrial import inner membrane translocase subunit TIM23, putative | 0.004 | 0.0282 | 0.4218 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0145 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0034 | 0.0027 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0199 | 0.158 | 0.1701 |
Brugia malayi | Death domain containing protein | 0.0032 | 0.021 | 0.0211 |
Schistosoma mansoni | netrin receptor unc5 | 0.0032 | 0.021 | 0.0211 |
Echinococcus multilocularis | protein dispatched 1 | 0.0048 | 0.0345 | 0.0352 |
Brugia malayi | Carboxylesterase family protein | 0.0199 | 0.158 | 0.1641 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0245 | 0.3652 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0031 | 0.0152 |
Schistosoma mansoni | DNA ligase IV | 0.001 | 0.0031 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0034 | 0.0027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0031 | 0.0152 |
Toxoplasma gondii | TIM10 family protein, putative | 0.0048 | 0.0341 | 0.3438 |
Brugia malayi | hypothetical protein | 0.001 | 0.0031 | 0.0025 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0308 | 0.248 | 0.2579 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.001 | 0.0031 | 0.0025 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0245 | 0.0264 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0034 | 0.0027 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0034 | 0.0027 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0245 | 0.245 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0096 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0211 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0245 | 0.0248 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0086 | 0.0659 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0034 | 0.0027 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0086 | 0.0659 | 0.6707 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0034 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.158 | 0.1641 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0245 | 0.3652 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0034 | 0.0027 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0145 | 0.0137 |
Wolbachia endosymbiont of Brugia malayi | NAD-dependent DNA ligase, Lig | 0.001 | 0.0031 | 1 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0034 | 0.0027 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0355 | 0.0363 |
Loa Loa (eye worm) | hypothetical protein | 0.0236 | 0.1884 | 0.1958 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0018 | 0.001 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0008 | 0.0009 |
Brugia malayi | topoisomerase | 0.001 | 0.0031 | 0.0025 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0199 | 0.158 | 1 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0086 | 0.0659 | 0.0679 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0032 | 0.021 | 0.0211 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0034 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0034 | 0.0027 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0007 | 0.0008 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0025 |
Onchocerca volvulus | 0.0024 | 0.0145 | 0.0873 | |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.158 | 0.1641 |
Echinococcus granulosus | tumor protein p63 | 0.0337 | 0.2714 | 0.2823 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0096 | 0.0092 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0034 | 0.0027 |
Onchocerca volvulus | 0.001 | 0.0031 | 0.0152 | |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0034 | 0.0027 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0032 | 0.021 | 0.0211 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0034 | 0.0027 |
Schistosoma mansoni | gliotactin | 0.0199 | 0.158 | 0.1641 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0034 | 0.0027 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0229 | 0.1832 | 0.1971 |
Brugia malayi | hypothetical protein | 0.0236 | 0.1884 | 0.1958 |
Onchocerca volvulus | 0.0049 | 0.0355 | 0.2212 | |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0284 | 0.0288 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0034 | 0.0027 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0007 | 0.0008 | 0.0006 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0245 | 0.245 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.0018 | 0.001 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0008 | 0.0009 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0125 | 0.0978 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0145 | 0.0143 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0086 | 0.0659 | 1 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.0296 | 0.0301 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0125 | 0.0978 | 0.0972 |
Onchocerca volvulus | Netrin receptor homolog | 0.0032 | 0.021 | 0.1285 |
Plasmodium vivax | hypothetical protein, conserved | 0.0086 | 0.0659 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.0337 | 0.2714 | 0.2823 |
Echinococcus granulosus | smad | 0.0008 | 0.0018 | 0.001 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.001 | 0.0031 | 0.0368 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0245 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0374 | 0.0382 |
Brugia malayi | Smad1 | 0.0008 | 0.0018 | 0.001 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0018 | 0.001 |
Echinococcus granulosus | acetylcholinesterase | 0.1176 | 0.9593 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0145 | 0.0137 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0034 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.1176 | 0.9593 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0245 | 0.0248 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0245 | 0.0264 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.001 | 0.0031 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0145 | 0.0143 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0098 | 0.0756 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0125 | 0.0978 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0659 | 0.0679 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0034 | 0.0027 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.001 | 0.0031 | 0.0362 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0145 | 0.0137 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0125 | 0.0978 | 0.1013 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0034 | 0.0027 |
Onchocerca volvulus | 0.0007 | 0.0008 | 0.0002 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.1176 | 0.9593 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0145 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0025 |
Loa Loa (eye worm) | transport to inner mitochondrial membrane family member | 0.0048 | 0.0341 | 0.0348 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0018 | 0.001 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0245 | 0.1512 |
Brugia malayi | follicle stimulating hormone receptor | 0.0231 | 0.1845 | 0.1916 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0086 | 0.0659 | 0.0679 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.158 | 0.1641 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0032 | 0.021 | 0.0211 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0199 | 0.158 | 0.1641 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.0927 | 0.0959 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0025 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0245 | 0.1512 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.001 | 0.0031 | 0.0368 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0199 | 0.158 | 0.1641 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0025 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0032 | 0.021 | 0.0211 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0034 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.158 | 0.1641 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0007 | 0.0008 | 0.0006 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0125 | 0.0978 | 0.1053 |
Echinococcus multilocularis | mitochondrial import inner membrane translocase subunit TIM23, putative | 0.004 | 0.0282 | 0.0287 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0296 | 0.1837 |
Brugia malayi | Carboxylesterase family protein | 0.0199 | 0.158 | 0.1641 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0245 | 0.0248 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0245 | 0.0248 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0145 | 0.2109 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1176 | 0.9593 | 1 |
Toxoplasma gondii | ATPase, AAA family protein | 0.001 | 0.0031 | 0.0247 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0007 | 0.0008 | 0.0006 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0034 | 0.0027 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0034 | 0.0166 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0034 | 0.0027 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.001 | 0.0031 | 0.0368 |
Brugia malayi | hypothetical protein | 0.0036 | 0.025 | 0.0253 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0034 | 0.0027 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0034 | 0.0027 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1176 | 0.9593 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0199 | 0.158 | 0.1641 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.001 | 0.0031 | 0.1007 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0659 | 0.0679 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0199 | 0.158 | 0.1574 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.0008 | 0.0004 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0034 | 0.0027 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0007 | 0.0008 | 0.0009 |
Echinococcus granulosus | Ankyrin | 0.0032 | 0.0211 | 0.0212 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0007 | 0.0008 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0659 | 0.0679 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0199 | 0.158 | 0.1701 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0809 | 0.6581 | 0.6857 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.0008 | 0.0006 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0034 | 0.0027 |
Echinococcus multilocularis | acetylcholinesterase | 0.1176 | 0.9593 | 1 |
Toxoplasma gondii | propionate-CoA ligase | 0.0007 | 0.0008 | 0.0004 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0034 | 0.0027 |
Brugia malayi | hypothetical protein | 0.001 | 0.0031 | 0.0025 |
Brugia malayi | Carboxylesterase family protein | 0.1176 | 0.9593 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1176 | 0.9593 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0231 | 0.1845 | 0.1916 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.01 | 0.0768 | 0.0794 |
Brugia malayi | DKFZp564C0469 protein | 0.001 | 0.0031 | 0.0025 |
Brugia malayi | Carboxylesterase family protein | 0.1176 | 0.9593 | 1 |
Echinococcus multilocularis | Ankyrin | 0.0032 | 0.0211 | 0.0212 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0007 | 0.0008 | 0.0009 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.0927 | 0.0959 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0145 | 0.1414 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0096 | 0.0092 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0688 | 0.5593 | 0.5827 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0034 | 0.0027 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0145 | 0.1835 |
Mycobacterium tuberculosis | Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) | 0.0007 | 0.0008 | 0.0008 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0284 | 0.0288 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0688 | 0.5593 | 0.5827 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0125 | 0.0978 | 0.1013 |
Onchocerca volvulus | 0.0007 | 0.0008 | 0.0002 | |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.0145 | 0.1835 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0034 | 0.0027 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.0296 | 0.0301 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0086 | 0.0659 | 0.0679 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0034 | 0.0027 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.001 | 0.0031 | 0.0368 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0086 | 0.0659 | 1 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.001 | 0.0031 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0756 | 0.0781 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0086 | 0.0659 | 0.0679 |
Echinococcus multilocularis | expressed conserved protein | 0.0092 | 0.0707 | 0.073 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0096 | 0.1351 |
Schistosoma mansoni | topbp1 | 0.001 | 0.0031 | 0.0025 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0245 | 0.0248 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0018 | 0.001 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0088 | 0.0095 |
Mycobacterium tuberculosis | Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 | 0.0007 | 0.0008 | 0.0008 |
Onchocerca volvulus | 0.0199 | 0.158 | 1 | |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0007 | 0.0008 | 0.0008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0245 | 0.3652 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0034 | 0.0027 |
Brugia malayi | CHE-14 protein | 0.0042 | 0.0296 | 0.0301 |
Echinococcus granulosus | acetylcholinesterase | 0.1176 | 0.9593 | 1 |
Leishmania major | UDP-galactopyranose mutase | 0.0086 | 0.0659 | 0.6707 |
Brugia malayi | Mitochondrial import inner membrane translocase subunit Tim17 family protein | 0.004 | 0.0282 | 0.0287 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0088 | 0.0095 |
Schistosoma mansoni | acetylcholinesterase | 0.0199 | 0.158 | 0.1641 |
Brugia malayi | Mitochondrial import inner membrane translocase subunit Tim17 family protein | 0.004 | 0.0282 | 0.0287 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0086 | 0.0659 | 0.0679 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0034 | 0.0027 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0088 | 0.0095 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0345 | 0.0352 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0034 | 0.0027 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0345 | 0.0352 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase (NAD+) dependent | 0.0007 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0145 | 0.0156 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0034 | 0.0027 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0007 | 0.0008 | 0.0006 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0008 | 0.0002 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0098 | 0.0756 | 0.0781 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0245 | 0.0264 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0199 | 0.158 | 0.1641 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0034 | 0.0027 |
Toxoplasma gondii | mitochondrial import inner membrane translocase subunit TIM10, putative | 0.0048 | 0.0341 | 0.3438 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0145 | 0.0143 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0034 | 0.0027 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0034 | 0.0027 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0034 | 0.0166 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0199 | 0.158 | 0.1641 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0018 | 0.001 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0086 | 0.0659 | 0.0709 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0034 | 0.0027 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0145 | 0.0137 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.0296 | 0.0301 |
Schistosoma mansoni | mitochondrial import inner membrane translocase subunit tim10 | 0.0048 | 0.0341 | 0.0348 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0034 | 0.0027 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.0018 | 0.001 |
Mycobacterium tuberculosis | Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 | 0.0007 | 0.0008 | 0.0008 |
Echinococcus multilocularis | nibrin | 0.001 | 0.0031 | 0.0025 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.001 | 0.0031 | 0.0368 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.001 | 0.0031 | 0.0362 |
Brugia malayi | Mitochondrial import inner membrane translocase subunit TIM10 | 0.0048 | 0.0341 | 0.0348 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0199 | 0.158 | 0.1641 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0008 | 0.0009 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0034 | 0.0027 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0245 | 0.1512 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0086 | 0.0659 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0284 | 0.0288 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0018 | 0.001 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.0018 | 0.001 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.001 | 0.0031 | 0.0025 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0199 | 0.158 | 0.1641 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.0927 | 0.0959 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0034 | 0.0027 |
Treponema pallidum | DNA ligase (lig) | 0.001 | 0.0031 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.0018 | 0.001 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0031 | 0.0152 |
Brugia malayi | hypothetical protein | 0.0086 | 0.0659 | 0.0679 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0031 | 0.0152 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0007 | 0.0008 | 0.0004 |
Onchocerca volvulus | 0.001 | 0.0034 | 0.0166 | |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0007 | 0.0008 | 0.0009 |
Onchocerca volvulus | 0.0036 | 0.0245 | 0.1512 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0245 | 0.0248 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) | 0.0007 | 0.0008 | 0.0008 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0245 | 0.1512 |
Loa Loa (eye worm) | hypothetical protein | 0.1176 | 0.9593 | 1 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0086 | 0.0659 | 0.0652 |
Brugia malayi | Carboxylesterase family protein | 0.0199 | 0.158 | 0.1641 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0245 | 0.0264 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0245 | 0.0248 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0034 | 0.0027 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0034 | 0.0027 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0125 | 0.0978 | 0.1013 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0034 | 0.0027 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0125 | 0.0978 | 0.0972 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0034 | 0.0027 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0086 | 0.0659 | 0.6707 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0034 | 0.0027 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0199 | 0.158 | 0.1641 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0096 | 0.1026 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CT10 ratio (functional) | > 3 | The ratio of the cytotoxicities against UV4 cell line in the air and N2 was measured using clonogenic assay | ChEMBL. | 8035424 |
CT50 (functional) | = 19 uM | Tested for the product of drug concentration and exposure time required to reduce UV4 cell survival under hypoxic condition by clonogenic assay | ChEMBL. | 8035424 |
IC50 (functional) | > 25 uM | Aerobic cytotoxicity of the compound was assessed in a growth inhibition assay using log phase cultures of the chinese hamster ovary fibroblast line AA8 | ChEMBL. | 8035424 |
IC50 ratio (functional) | > 1 | Ratio of the cytotoxicities against drug induced aerobic Walker cells and chinese hamster ovary fibroblast line AA8 | ChEMBL. | 8035424 |
IC50 ratio (functional) | > 2 | Tested for hypersensitivity factor which is the ratio of cytotoxicities against drug induced hypoxic UV4 cells and chinese hamster ovary fibroblast line AA8 | ChEMBL. | 8035424 |
S | = 0.038 mM | Solubility (alpha-MEM culture medium, containing 5% fetal calf serum) | ChEMBL. | 8035424 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.