Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.2251 | 0.3367 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0045 | 0.0945 | 0.1187 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.0945 | 0.0945 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0712 | 0.0769 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0265 | 0.6604 | 0.6604 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0945 | 0.1377 |
Wolbachia endosymbiont of Brugia malayi | NADH dehydrogenase subunit H | 0.0146 | 0.3544 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0265 | 0.6604 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0265 | 0.6604 | 0.6604 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0712 | 0.1019 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0712 | 0.0796 |
Echinococcus granulosus | carboxylesterase 5A | 0.0265 | 0.6604 | 0.6604 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0712 | 0.0712 |
Trichomonas vaginalis | set domain proteins, putative | 0.0236 | 0.585 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0045 | 0.0945 | 0.1373 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0712 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.0945 | 0.0945 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0644 | 0.0644 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.0945 | 0.0945 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.2102 | 0.2102 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.118 | 1 |
Onchocerca volvulus | 0.0036 | 0.0712 | 0.0377 | |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0045 | 0.0945 | 0.0945 |
Echinococcus granulosus | acetylcholinesterase | 0.0265 | 0.6604 | 0.6604 |
Onchocerca volvulus | 0.0045 | 0.0945 | 0.0813 | |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0284 | 0.2624 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0188 | 0.0224 |
Onchocerca volvulus | 0.003 | 0.0571 | 0.0113 | |
Loa Loa (eye worm) | carboxylesterase | 0.0265 | 0.6604 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0188 | 0.0188 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0712 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0188 | 0.0219 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0644 | 0.0919 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1085 | 0.1588 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0712 | 0.0769 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0571 | 0.0571 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0848 | 0.1013 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0045 | 0.0945 | 0.0945 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0712 | 0.1313 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.3544 | 0.3544 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.1342 | 0.1342 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0551 | 0.0551 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0945 | 0.1373 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0284 | 0.2624 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0712 | 0.0712 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0284 | 0.2624 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0945 | 0.1377 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0045 | 0.0945 | 0.1187 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0045 | 0.0945 | 0.2026 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0045 | 0.0945 | 0.1229 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0945 | 0.1377 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0712 | 0.0796 |
Brugia malayi | Pre-SET motif family protein | 0.0207 | 0.5116 | 0.7734 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0284 | 0.0284 |
Onchocerca volvulus | 0.0045 | 0.0945 | 0.0813 | |
Echinococcus granulosus | NADH dehydrogenase subunit 1 | 0.0146 | 0.3544 | 0.3544 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0284 | 0.2624 |
Onchocerca volvulus | 0.0045 | 0.0945 | 0.0813 | |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0712 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0188 | 0.0188 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0265 | 0.6604 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0045 | 0.0945 | 0.0945 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0945 | 0.1373 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0803 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0644 | 0.0916 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0527 | 0.0527 |
Schistosoma mansoni | gliotactin | 0.0045 | 0.0945 | 0.0945 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0848 | 0.1226 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0284 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0284 | 0.2624 |
Brugia malayi | Carboxylesterase family protein | 0.0265 | 0.6604 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0265 | 0.6604 | 0.6604 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.6604 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0265 | 0.6604 | 0.6604 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0284 | 0.0367 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0712 | 0.0712 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0712 | 0.0796 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0284 | 0.2624 |
Brugia malayi | NADH dehydrogenase subunit 1 | 0.0039 | 0.0803 | 0.1162 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0207 | 0.5116 | 0.7733 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0712 | 0.1023 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0045 | 0.0945 | 0.0945 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0848 | 0.0848 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0712 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0188 | 0.0188 |
Schistosoma mansoni | NADH dehydrogenase subunit 1 | 0.0039 | 0.0803 | 0.0803 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0284 | 0.0367 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0045 | 0.0945 | 0.1229 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0284 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.4099 | 0.4099 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0284 | 0.0284 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0571 | 0.0571 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0712 | 0.0796 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0188 | 0.0188 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0137 | 0.3305 | 0.3305 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0945 | 0.1373 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0284 | 0.2624 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0571 | 0.0571 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0044 | 0.0044 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0284 | 0.2624 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0712 | 0.1019 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.2102 | 0.2102 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.4099 | 0.4099 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0712 | 0.1019 |
Loa Loa (eye worm) | carboxylesterase | 0.0045 | 0.0945 | 0.1373 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0712 | 0.1019 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0712 | 0.0796 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0712 | 0.1023 |
Echinococcus multilocularis | geminin | 0.0168 | 0.4099 | 0.4099 |
Loa Loa (eye worm) | NADH dehydrogenase subunit 1 | 0.0039 | 0.0803 | 0.1158 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.1038 | 0.1516 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.1038 | 0.1519 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.081 | 0.081 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H) | 0.0146 | 0.3544 | 0.6064 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0712 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0045 | 0.0945 | 0.0945 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0945 | 0.1377 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0188 | 0.0188 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0551 | 0.0551 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.1038 | 0.1519 |
Echinococcus granulosus | neuroligin | 0.0045 | 0.0945 | 0.0945 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0188 | 0.0224 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0712 | 0.0796 |
Mycobacterium tuberculosis | Possible formate hydrogenlyase HycD (FHL) | 0.0039 | 0.0803 | 0.0966 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.081 | 0.081 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0284 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.0397 | 1 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0511 | 0.0511 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0284 | 0.2624 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0551 | 0.0551 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0284 | 0.0284 |
Onchocerca volvulus | 0.0039 | 0.0803 | 0.0548 | |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0945 | 0.1377 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0945 | 0.1373 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0284 | 0.2624 |
Echinococcus granulosus | geminin | 0.0168 | 0.4099 | 0.4099 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0712 | 0.0712 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0571 | 0.0571 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0188 | 0.0188 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0712 | 0.0796 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.2251 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0284 | 0.2624 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0712 | 0.1023 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0137 | 0.3305 | 0.3305 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0712 | 0.1019 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0045 | 0.0945 | 0.0945 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0571 | 0.0571 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0712 | 0.1019 |
Onchocerca volvulus | 0.0045 | 0.0945 | 0.0813 | |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0712 | 0.232 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0712 | 0.1313 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0712 | 0.0796 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0848 | 0.0848 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0284 | 0.0284 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0712 | 0.1313 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0284 | 0.0371 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0284 | 0.2624 |
Echinococcus granulosus | acetylcholinesterase | 0.0265 | 0.6604 | 0.6604 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0284 | 0.0371 |
Mycobacterium ulcerans | NADH dehydrogenase subunit H | 0.0146 | 0.3544 | 1 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0848 | 0.1226 |
Onchocerca volvulus | 0.0036 | 0.0712 | 0.0377 | |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.2251 | 0.2251 |
Echinococcus multilocularis | neuroligin | 0.0045 | 0.0945 | 0.0945 |
Schistosoma mansoni | acetylcholinesterase | 0.0045 | 0.0945 | 0.0945 |
Onchocerca volvulus | 0.0045 | 0.0945 | 0.0813 | |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0712 | 0.0769 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0997 | 0.0997 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0044 | 0.0044 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0045 | 0.0945 | 0.0945 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.081 | 0.081 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0284 | 0.0284 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0188 | 0.0188 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0097 | 0.2289 | 0.2289 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0848 | 0.0848 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0712 | 0.0796 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0712 | 0.1023 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0712 | 1 |
Onchocerca volvulus | 0.0039 | 0.0803 | 0.0548 | |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0571 | 0.0807 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0945 | 0.1373 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0571 | 0.0571 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0712 | 0.0796 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0188 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0712 | 0.1019 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.6604 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0571 | 0.0804 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0712 | 0.0769 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0551 | 0.0551 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0284 | 0.2624 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0284 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.2251 | 0.3364 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0284 | 0.2624 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0284 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0188 | 0.0188 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0848 | 0.123 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0188 | 0.0219 |
Onchocerca volvulus | 0.0036 | 0.0712 | 0.0377 | |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0848 | 0.0848 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0848 | 0.0848 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0712 | 0.1019 |
Brugia malayi | NADH dehydrogenase subunit 1, identical | 0.0039 | 0.0803 | 0.1162 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.081 | 0.081 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0511 | 0.0712 |
Mycobacterium ulcerans | formate hydrogenlyase HycD | 0.0039 | 0.0803 | 0.1593 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0712 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0188 | 0.0188 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0712 | 0.0769 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.2251 | 0.2251 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0712 | 0.0769 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0712 | 0.1313 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1038 | 0.1516 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0397 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0045 | 0.0945 | 0.1229 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0712 | 0.1313 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0284 | 0.2624 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0045 | 0.0945 | 0.0945 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0511 | 0.0716 |
Onchocerca volvulus | 0.0236 | 0.585 | 1 | |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0571 | 0.0571 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0945 | 0.1373 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0228 | 0.5659 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0945 | 0.1373 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | > 99 uM | PUBCHEM_BIOASSAY: SAR Analysis of small molecule inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2540, AID2599, AID434973, AID489001] | ChEMBL. | No reference |
IC50 (functional) | > 99 uM | PUBCHEM_BIOASSAY: SAR Analysis of small molecule inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2582, AID2599] | ChEMBL. | No reference |
IC50 (functional) | > 99 uM | PUBCHEM_BIOASSAY: SAR Analysis of small molecule inhibitors of Sentrin-specific protease 7 (SENP7) using a Luminescent assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID434973, AID434986] | ChEMBL. | No reference |
IC50 (functional) | > 99 uM | PUBCHEM_BIOASSAY: SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2540, AID2575] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.