Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.4466 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0073 | 0.423 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0014 | 0.0435 | 0.2537 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0152 | 0.9225 | 0.9207 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Schistosoma mansoni | ap endonuclease | 0.0023 | 0.1017 | 0.1017 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.423 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.001 | 0.0237 | 0.0237 |
Onchocerca volvulus | Cathepsin F homolog | 0.002 | 0.0859 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0023 | 0.1017 | 0.1017 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0077 | 0.4466 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0435 | 0.1249 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.4466 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Brugia malayi | Papain family cysteine protease containing protein | 0.002 | 0.0859 | 0.2468 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.4466 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0062 | 0.3481 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0062 | 0.3481 | 0.7796 |
Plasmodium vivax | vivapain-1 | 0.001 | 0.0237 | 0.2328 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0012 | 0.035 | 0.1006 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0062 | 0.3481 | 0.7796 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0152 | 0.9225 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0062 | 0.3481 | 0.7673 |
Echinococcus multilocularis | cysteine protease | 0.002 | 0.0859 | 0.0637 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0062 | 0.3481 | 0.361 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.001 | 0.0237 | 0.0237 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0012 | 0.035 | 0.1006 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.035 | 0.1006 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0012 | 0.035 | 0.1006 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0062 | 0.3481 | 0.7796 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0859 | 0.2468 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.002 | 0.0859 | 0.2468 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0012 | 0.035 | 0.0116 |
Brugia malayi | cathepsin L-like precursor | 0.0014 | 0.0435 | 0.1249 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0062 | 0.3481 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.035 | 0.1006 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.035 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.035 | 0.1006 |
Schistosoma mansoni | coup transcription factor | 0.0012 | 0.035 | 0.035 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.4466 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.001 | 0.0237 | 0.053 |
Brugia malayi | Cathepsin L-like precursor | 0.0014 | 0.0435 | 0.1249 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0012 | 0.035 | 0.1006 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0023 | 0.1017 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.001 | 0.0237 | 0.053 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0012 | 0.035 | 0.1006 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0073 | 0.423 | 0.9347 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.3481 | 0.3481 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0073 | 0.423 | 0.423 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0023 | 0.1017 | 0.2405 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.4466 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0859 | 0.2468 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0012 | 0.035 | 0.1006 |
Trypanosoma brucei | protein kinase, putative | 0.0062 | 0.3481 | 0.7673 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0023 | 0.1017 | 0.2278 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0023 | 0.1017 | 0.2922 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.035 | 0.1006 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Entamoeba histolytica | cysteine protease, putative | 0.002 | 0.0859 | 0.7974 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.002 | 0.0859 | 0.0692 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0023 | 0.1017 | 0.1845 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.4466 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0012 | 0.035 | 0.1006 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0014 | 0.0435 | 0.061 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0012 | 0.035 | 0.1006 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0023 | 0.1017 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0012 | 0.035 | 0.1006 |
Echinococcus granulosus | cathepsin l1 | 0.002 | 0.0859 | 0.0692 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0012 | 0.035 | 0.1006 |
Leishmania major | cathepsin L-like protease | 0.0077 | 0.4466 | 1 |
Leishmania major | cathepsin L-like protease | 0.0077 | 0.4466 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0152 | 0.9225 | 0.9225 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.4466 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0012 | 0.035 | 0.1006 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.001 | 0.0237 | 0.0237 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.035 | 0.1006 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0023 | 0.1017 | 0.0799 |
Onchocerca volvulus | 0.002 | 0.0859 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.002 | 0.0859 | 0.7974 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.4466 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0859 | 0.2468 |
Brugia malayi | steroid hormone receptor | 0.0012 | 0.035 | 0.1006 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.002 | 0.0859 | 0.7974 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.035 | 0.1006 |
Schistosoma mansoni | nuclear hormone receptor | 0.0012 | 0.035 | 0.035 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.035 | 0.0126 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0012 | 0.035 | 0.0126 |
Brugia malayi | Cathepsin L-like precursor | 0.0014 | 0.0435 | 0.1249 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.001 | 0.0237 | 0.053 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0012 | 0.035 | 0.1006 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.035 | 0.0126 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0023 | 0.1017 | 0.0868 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0073 | 0.423 | 0.409 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0012 | 0.035 | 0.035 |
Echinococcus granulosus | FTZ F1 alpha | 0.0012 | 0.035 | 0.0126 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0073 | 0.423 | 0.4442 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.035 | 0.0116 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.0859 | 0.0859 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.002 | 0.0859 | 0.7974 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.4466 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0062 | 0.3481 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.002 | 0.0859 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0012 | 0.035 | 0.035 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.4466 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0014 | 0.0435 | 0.061 |
Plasmodium vivax | vivapain-2 | 0.002 | 0.0859 | 0.8446 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.002 | 0.0859 | 0.0637 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0023 | 0.1017 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.002 | 0.0859 | 0.7974 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0062 | 0.3481 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0062 | 0.3481 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.002 | 0.0859 | 0.7974 |
Brugia malayi | Papain family cysteine protease containing protein | 0.001 | 0.0237 | 0.068 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.035 | 0.1006 |
Loa Loa (eye worm) | cysteine protease | 0.002 | 0.0859 | 0.2468 |
Onchocerca volvulus | 0.002 | 0.0859 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.002 | 0.0859 | 0.0692 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0073 | 0.423 | 0.423 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.035 | 0.0116 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0012 | 0.035 | 0.1006 |
Plasmodium vivax | vivapain-3 | 0.001 | 0.0237 | 0.2328 |
Brugia malayi | ecdysteroid receptor | 0.0012 | 0.035 | 0.1006 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.035 | 0.1006 |
Schistosoma mansoni | thyroid hormone receptor | 0.0164 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Onchocerca volvulus | Cathepsin L homolog | 0.002 | 0.0859 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0012 | 0.035 | 0.1006 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0023 | 0.1017 | 0.2278 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0062 | 0.3481 | 0.3323 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0012 | 0.035 | 0.1006 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0023 | 0.1017 | 0.5 |
Onchocerca volvulus | 0.002 | 0.0859 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0012 | 0.035 | 0.0126 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0012 | 0.035 | 0.035 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.002 | 0.0859 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.035 | 0.1006 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0014 | 0.0435 | 0.0435 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.4466 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.035 | 0.0116 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0062 | 0.3481 | 0.7271 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.423 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.002 | 0.0859 | 0.0637 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.001 | 0.0237 | 0.053 |
Onchocerca volvulus | 0.0014 | 0.0435 | 0.166 | |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.007 | 0.4041 | 0.905 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.035 | 0.1006 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0077 | 0.4466 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.035 | 0.1006 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.035 | 0.0126 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0012 | 0.035 | 0.1006 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0859 | 0.2468 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.035 | 0.1006 |
Loa Loa (eye worm) | fibroinase | 0.002 | 0.0859 | 0.2468 |
Onchocerca volvulus | 0.002 | 0.0859 | 1 | |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0023 | 0.1017 | 0.0438 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.0859 | 0.0859 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0023 | 0.1017 | 0.2922 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0062 | 0.3481 | 0.3323 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0062 | 0.3481 | 0.7796 |
Brugia malayi | Papain family cysteine protease containing protein | 0.001 | 0.0237 | 0.068 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Onchocerca volvulus | 0.002 | 0.0859 | 1 | |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0073 | 0.423 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.035 | 0.035 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0012 | 0.035 | 0.035 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Trypanosoma cruzi | cysteine protease, putative | 0.001 | 0.0237 | 0.053 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0062 | 0.3481 | 0.7271 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.002 | 0.0859 | 0.0637 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0062 | 0.3481 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0012 | 0.035 | 0.0116 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Loa Loa (eye worm) | ctsf protein | 0.002 | 0.0859 | 0.2468 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.002 | 0.0859 | 0.0637 |
Plasmodium vivax | vivapain-2 | 0.002 | 0.0859 | 0.8446 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.423 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0012 | 0.035 | 0.035 |
Leishmania major | cathepsin L-like protease | 0.0077 | 0.4466 | 1 |
Echinococcus multilocularis | cysteine protease | 0.002 | 0.0859 | 0.0637 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.035 | 0.0116 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0859 | 0.2468 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0012 | 0.035 | 0.035 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0012 | 0.035 | 0.0116 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0061 | 0.3419 | 0.7656 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.035 | 0.0126 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.035 | 0.1006 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0062 | 0.3481 | 0.361 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0012 | 0.035 | 0.0126 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0012 | 0.035 | 0.035 |
Brugia malayi | nuclear receptor NHR-88 | 0.0012 | 0.035 | 0.1006 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0012 | 0.035 | 0.1006 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0435 | 0.1249 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.035 | 0.0116 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0859 | 0.2468 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Plasmodium vivax | unspecified product | 0.001 | 0.0237 | 0.2328 |
Onchocerca volvulus | 0.002 | 0.0859 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0012 | 0.035 | 0.035 |
Echinococcus granulosus | cathepsin l1 | 0.0014 | 0.0435 | 0.022 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0859 | 0.1918 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0014 | 0.0435 | 0.1249 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0023 | 0.1017 | 0.2405 |
Onchocerca volvulus | 0.002 | 0.0859 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0012 | 0.035 | 0.1006 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.002 | 0.0859 | 0.2468 |
Schistosoma mansoni | thyroid hormone receptor | 0.0164 | 1 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0062 | 0.3481 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0859 | 0.2468 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0435 | 0.1249 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0062 | 0.3481 | 0.7779 |
Toxoplasma gondii | exonuclease III APE | 0.0023 | 0.1017 | 0.0469 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0077 | 0.4466 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.035 | 0.1006 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0023 | 0.1017 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0077 | 0.4466 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.035 | 0.1006 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.