Detailed information for compound 113028

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 297.391 | Formula: C19H23NO2
  • H donors: 2 H acceptors: 2 LogP: 4.37 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CC[C@H]1CCC(c2c1c1ccccc1[nH]2)(CC)CC(=O)O
  • InChi: 1S/C19H23NO2/c1-3-7-13-10-11-19(4-2,12-16(21)22)18-17(13)14-8-5-6-9-15(14)20-18/h3,5-6,8-9,13,20H,1,4,7,10-12H2,2H3,(H,21,22)/t13-,19?/m0/s1
  • InChiKey: FGKWVMZCJYNYTQ-YTJLLHSVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0036 0.0018 0.0015
Echinococcus multilocularis growth factor receptor bound protein 2 0.0144 0.014 0.0166
Loa Loa (eye worm) hypothetical protein 0.0044 0.0027 0.0025
Schistosoma mansoni hypothetical protein 0.003 0.001 0.0004
Toxoplasma gondii subtilisin SUB6 0.0391 0.0419 1
Entamoeba histolytica hypothetical protein 0.0043 0.0026 0.0201
Brugia malayi Stress-activated protein kinase jnk-1 0.024 0.0249 0.0246
Loa Loa (eye worm) transcriptional regulator 0.0105 0.0096 0.0093
Brugia malayi BmSERPIN, truncated 0.0029 0.001 0.0007
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0096 0.0146
Loa Loa (eye worm) hypothetical protein 0.0105 0.0096 0.0093
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0036 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0007
Brugia malayi proprotein convertase 2 0.5603 0.6313 0.6312
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0024 0.0004 0.0089
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0144 0.014 0.0137
Brugia malayi CUB domain containing protein 0.0026 0.0007 0.0004
Onchocerca volvulus 0.0039 0.0022 0.0318
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2161 0.2421 0.3957
Brugia malayi von Willebrand factor type A domain containing protein 0.003 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0098 0.0087 0.0922
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0003
Echinococcus multilocularis laminin 0.0026 0.0007 0.0000097742
Schistosoma mansoni dock 0.0044 0.0027 0.0021
Loa Loa (eye worm) TK/EGFR protein kinase 0.0631 0.0691 0.0688
Schistosoma mansoni inositol transporter 0.0296 0.0312 0.0305
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0059 0.0043 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0004
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0062 0.0048 0.0041
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0036 0.0018 0.0433
Loa Loa (eye worm) endoprotease bli-4 0.8864 1 1
Toxoplasma gondii aspartyl protease 0.0036 0.0018 0.029
Loa Loa (eye worm) DEAH box polypeptide 35 0.0034 0.0015 0.0012
Trichomonas vaginalis hypothetical protein 0.177 0.1979 0.3232
Echinococcus multilocularis high affinity choline transporter 1 0.0076 0.0063 0.007
Brugia malayi hypothetical protein 0.0036 0.0018 0.0015
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0043 0.0026 0.0019
Echinococcus granulosus Furin 1 0.2161 0.2421 0.2416
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0391 0.0419 1
Brugia malayi ADAM-TS Spacer 1 family protein 0.0025 0.0006 0.0003
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0103 0.0093 0.2228
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0105 0.0096 0.0111
Brugia malayi Zinc metalloproteinase toh-2 precursor 0.0026 0.0007 0.0004
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0098 0.0087 0.0974
Loa Loa (eye worm) chitinase I 0.0073 0.006 0.0057
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Loa Loa (eye worm) hypothetical protein 0.0073 0.006 0.0057
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0108 0.0099 0.0096
Echinococcus granulosus plasminogen activator inhibitor 2 0.0029 0.001 0.0003
Brugia malayi von Willebrand factor type A domain containing protein 0.003 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0506 0.0549 0.0547
Echinococcus multilocularis neuroendocrine convertase 2 0.5603 0.6313 0.7891
Giardia lamblia High cysteine membrane protein Group 2 0.3261 0.3664 1
Brugia malayi Integrin alpha cytoplasmic region family protein 0.052 0.0565 0.0563
Onchocerca volvulus Fatty acid synthase homolog 0.0044 0.0027 0.0401
Plasmodium falciparum subtilisin-like protease 3 0.0391 0.0419 0.9514
Schistosoma mansoni tyrosine kinase 0.0631 0.0691 0.0685
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0018 0.0011
Mycobacterium ulcerans dehydrogenase 0.0103 0.0093 0.2228
Brugia malayi amine oxidase, flavin-containing family protein 0.0146 0.0142 0.0139
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0105 0.0096 0.0111
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.177 0.1979 0.3232
Entamoeba histolytica SWIRM domain protein 0.0043 0.0026 0.0201
Mycobacterium ulcerans monoamine oxidase 0.0103 0.0093 0.2228
Echinococcus multilocularis solute carrier family 5 0.0296 0.0312 0.0382
Brugia malayi CUB domain containing protein 0.0026 0.0007 0.0004
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0391 0.0419 0.0413
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0007
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0018 0.0011
Giardia lamblia Tenascin precursor 0.0091 0.008 0.0192
Plasmodium vivax subtilisin-like serine protease, putative 0.0391 0.0419 0.9514
Trichomonas vaginalis conserved hypothetical protein 0.177 0.1979 0.3232
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0391 0.0419 1
Brugia malayi hypothetical protein 0.0073 0.006 0.0057
Loa Loa (eye worm) hypothetical protein 0.0076 0.0063 0.006
Echinococcus granulosus discoidin domain containing receptor 2 0.0044 0.0027 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0391 0.0419 0.0676
Trypanosoma brucei SIR2-like protein 4, putative 0.0105 0.0096 0.1033
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0391 0.0419 0.0413
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0391 0.0419 0.0417
Brugia malayi hypothetical protein 0.0039 0.0022 0.0019
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0003
Brugia malayi Angiotensin-converting enzyme family protein 0.0709 0.0779 0.0776
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.177 0.1979 0.3232
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0712 0.0783 1
Brugia malayi CUB domain containing protein 0.0026 0.0007 0.0004
Mycobacterium ulcerans NAD-dependent deacetylase 0.0105 0.0096 0.2288
Brugia malayi zinc metalloproteinase toh-2 precursor 0.0026 0.0007 0.0004
Schistosoma mansoni serpin 0.0029 0.001 0.0003
Echinococcus granulosus adam 0.0148 0.0144 0.0138
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0103 0.0093 0.193
Trypanosoma cruzi subtilisin peptidase 0.0391 0.0419 0.5283
Loa Loa (eye worm) fatty acid synthase 0.0024 0.0004 0.0001
Schistosoma mansoni site-1 peptidase (S08 family) 0.0391 0.0419 0.0413
Brugia malayi Integrin beta pat-3 precursor 0.2829 0.3175 0.3173
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0105 0.0096 0.1989
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0023
Onchocerca volvulus 0.0039 0.0022 0.0318
Schistosoma mansoni furin-1 (S08 family) 0.3833 0.4311 0.4307
Echinococcus multilocularis discoidin domain containing receptor 2 0.0044 0.0027 0.0026
Brugia malayi astacin protease protein 30 0.0026 0.0007 0.0004
Schistosoma mansoni serine protease inhibitors serpins 0.0029 0.001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.177 0.1979 0.3232
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0105 0.0096 0.0089
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0018 0.0011
Plasmodium vivax plasmepsin V, putative 0.041 0.044 1
Brugia malayi EGF-like domain containing protein 0.0091 0.008 0.0077
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0103 0.0093 0.2109
Leishmania major arginine N-methyltransferase, type I 0.0035 0.0017 0.0057
Brugia malayi serpin 0.0029 0.001 0.0007
Trichomonas vaginalis hypothetical protein 0.0091 0.008 0.012
Onchocerca volvulus Putative endochitinase 0.0073 0.006 0.0954
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0096 0.0146
Loa Loa (eye worm) transcriptional regulator 0.0105 0.0096 0.0093
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0031 0.0012 0.0047
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0709 0.0779 0.0776
Giardia lamblia hypothetical protein 0.0043 0.0026 0.0042
Onchocerca volvulus 0.0049 0.0032 0.0493
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1286 0.1431 0.1425
Loa Loa (eye worm) cuticular endochitinase 0.0073 0.006 0.0057
Echinococcus granulosus voltage dependent calcium channel subunit 0.003 0.001 0.0004
Echinococcus granulosus furin 0.8864 1 1
Toxoplasma gondii calcium binding egf domain-containing protein 0.0026 0.0007 0.0016
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0053 0.0037 0.0034
Onchocerca volvulus 0.003 0.001 0.0129
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0049 0.0032 0.0029
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0019
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0103 0.0093 0.2228
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.003 0.001 0.0008
Toxoplasma gondii aspartyl protease ASP5 0.0373 0.0399 0.9508
Loa Loa (eye worm) hypothetical protein 0.0137 0.0132 0.0129
Schistosoma mansoni high-affinity choline transporter 0.0076 0.0063 0.0056
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.5422 0.6108 0.7634
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0105 0.0096 0.1084
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0506 0.0549 0.0679
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0026 0.0007 0.0004
Echinococcus granulosus lysine specific histone demethylase 1A 0.0506 0.0549 0.0543
Toxoplasma gondii subtilisin SUB2 0.0391 0.0419 1
Loa Loa (eye worm) hypothetical protein 0.0391 0.0419 0.0417
Schistosoma mansoni growth factor receptor-bound protein 0.0144 0.014 0.0133
Brugia malayi Kringle domain containing protein 0.0031 0.0012 0.001
Loa Loa (eye worm) reprolysin 0.0043 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.177 0.1979 0.3232
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0049 0.0032 0.0029
Loa Loa (eye worm) hypothetical protein 0.0091 0.008 0.0077
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0036 0.0018 0.0433
Trichomonas vaginalis conserved hypothetical protein 0.177 0.1979 0.3232
Brugia malayi Endochitinase 0.0073 0.006 0.0057
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.001
Onchocerca volvulus 0.0029 0.001 0.0121
Loa Loa (eye worm) hypothetical protein 0.0073 0.006 0.0057
Brugia malayi Reprolysin 0.0025 0.0006 0.0003
Brugia malayi Carm1-pending protein 0.0035 0.0017 0.0014
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0035 0.0017 0.001
Brugia malayi pregnancy-associated plasma protein-A 0.0039 0.0022 0.0019
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0005 0.0109
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0712 0.0783 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0047 0.0045
Loa Loa (eye worm) serpin 0.0029 0.001 0.0007
Brugia malayi hypothetical protein 0.0039 0.0022 0.0019
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0007
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0018 0.0011
Onchocerca volvulus 0.0039 0.0022 0.0318
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Plasmodium vivax aspartyl proteinase, putative 0.0036 0.0018 0.0182
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0018 0.0011
Echinococcus granulosus protein will die slowly 0.021 0.0214 0.0208
Onchocerca volvulus 0.0036 0.0018 0.026
Onchocerca volvulus 0.0039 0.0022 0.0318
Brugia malayi hypothetical protein 0.0039 0.0022 0.0019
Schistosoma mansoni protein kinase 0.0123 0.0116 0.011
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0103 0.0093 0.193
Onchocerca volvulus Putative endochitinase 0.0073 0.006 0.0954
Schistosoma mansoni memapsin-2 (A01 family) 0.0036 0.0018 0.0011
Onchocerca volvulus Putative endochitinase 0.0073 0.006 0.0954
Loa Loa (eye worm) CUB domain-containing protein 0.0026 0.0007 0.0004
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0076 0.0063 0.0056
Treponema pallidum hypothetical protein 0.003 0.001 0.5
Brugia malayi EGF-like domain containing protein 0.0091 0.008 0.0077
Trypanosoma cruzi UDP-galactopyranose mutase 0.0103 0.0093 0.1051
Entamoeba histolytica hypothetical protein, conserved 0.0105 0.0096 0.1112
Brugia malayi endochitinase 0.0073 0.006 0.0057
Brugia malayi serpin (BmSERPIN) 0.0029 0.001 0.0007
Mycobacterium tuberculosis Possible oxidoreductase 0.0103 0.0093 0.2228
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0417 0.0449 0.567
Onchocerca volvulus 0.0073 0.006 0.0953
Echinococcus granulosus high affinity choline transporter 1 0.0076 0.0063 0.0056
Echinococcus multilocularis chromatin regulatory protein sir2 0.0712 0.0783 0.0971
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0026 0.0031
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Plasmodium vivax aspartyl protease, putative 0.0036 0.0018 0.0182
Plasmodium falciparum subtilisin-like protease 2 0.0391 0.0419 0.9514
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.2161 0.2421 0.2416
Echinococcus multilocularis discoidin domain containing receptor 2 0.0044 0.0027 0.0026
Schistosoma mansoni chromatin regulatory protein sir2 0.0712 0.0783 0.0776
Toxoplasma gondii subtilisin SUB11 0.0391 0.0419 1
Echinococcus multilocularis protoporphyrinogen oxidase 0.0103 0.0093 0.0108
Echinococcus multilocularis Furin 1 0.2161 0.2421 0.3021
Giardia lamblia Tenascin-37 0.0091 0.008 0.0192
Brugia malayi GH02984p 0.0076 0.0063 0.006
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0035 0.0017 0.0016
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0018 0.0011
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0026 0.0006 0.015
Brugia malayi hypothetical protein 0.0039 0.0022 0.0019
Echinococcus multilocularis discoidin domain receptor 0.0044 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0103 0.0093 0.0091
Toxoplasma gondii subtilisin SUB9 0.0391 0.0419 1
Schistosoma mansoni serine protease inhibitors serpins 0.0029 0.001 0.0003
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0123 0.0116 0.011
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.8864 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Schistosoma mansoni SWI/SNF complex-related 0.0043 0.0026 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0018 0.0015
Brugia malayi celfurPC protein 0.7094 0.7999 0.7998
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Echinococcus multilocularis Tolloid protein 1 0.0053 0.0037 0.0037
Loa Loa (eye worm) CUTiclin family member 0.003 0.001 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.177 0.1979 0.3232
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0044 0.0027 0.0034
Brugia malayi serpin 0.0029 0.001 0.0007
Echinococcus granulosus SWI:SNF complex subunit SMARCC2 0.0043 0.0026 0.0019
Brugia malayi Protein arginine N-methyltransferase 0.0035 0.0017 0.0014
Brugia malayi Calcium binding EGF domain containing protein 0.0045 0.0029 0.0026
Brugia malayi Nematode astacin protease protein 30 0.0026 0.0007 0.0004
Brugia malayi Protein kinase domain containing protein 0.0031 0.0012 0.001
Loa Loa (eye worm) transcriptional regulator 0.0712 0.0783 0.078
Toxoplasma gondii subtilisin SUB7 0.0391 0.0419 1
Giardia lamblia Tenascin-X 0.0091 0.008 0.0192
Onchocerca volvulus 0.0076 0.0063 0.1005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0004
Onchocerca volvulus 0.0026 0.0007 0.0069
Loa Loa (eye worm) integrin alpha pat-2 0.1049 0.1164 0.1161
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0004
Leishmania major chitinase 0.0073 0.006 0.0612
Plasmodium vivax hypothetical protein, conserved 0.0105 0.0096 0.1989
Schistosoma mansoni cathepsin D (A01 family) 0.0036 0.0018 0.0011
Echinococcus granulosus integrin beta 2 0.2095 0.2346 0.2341
Schistosoma mansoni serine protease inhibitors serpins 0.0029 0.001 0.0003
Plasmodium vivax LCCL domain-containing protein 0.0044 0.0027 0.0394
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0036 0.0018 0.0019
Onchocerca volvulus 0.0044 0.0027 0.0414
Brugia malayi hypothetical protein 0.003 0.001 0.0008
Onchocerca volvulus 0.0026 0.0007 0.0069
Schistosoma mansoni protein kinase 0.0123 0.0116 0.011
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0035 0.0017 0.0057
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0024 0.0004 0.0089
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0043 0.0026 0.0019
Echinococcus granulosus c-Jun N-terminal kinases 0.024 0.0249 0.0242
Giardia lamblia Tenascin-like 0.0091 0.008 0.0192
Onchocerca volvulus 0.0172 0.0172 0.2845
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Entamoeba histolytica chitinase, putative 0.0073 0.006 0.0642
Toxoplasma gondii PA14 domain-containing protein 0.0044 0.0027 0.0511
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0053 0.0037 0.003
Echinococcus multilocularis integrin alpha ps 0.0509 0.0552 0.0683
Echinococcus granulosus serine protease inhibitor 0.0029 0.001 0.0003
Brugia malayi CUB domain containing protein 0.0026 0.0007 0.0004
Onchocerca volvulus 0.003 0.001 0.0129
Echinococcus multilocularis serine protease inhibitor 0.0029 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.3442 0.3869 0.3867
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0026 0.0006 0.015
Onchocerca volvulus 0.0042 0.0025 0.0372
Plasmodium falciparum apical sushi protein 0.0039 0.0022 0.0261
Onchocerca volvulus 0.021 0.0214 0.3557
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0018 0.0011
Loa Loa (eye worm) TK/ROR protein kinase 0.0031 0.0012 0.001
Plasmodium falciparum protoporphyrinogen oxidase 0.0103 0.0093 0.193
Mycobacterium ulcerans oxidoreductase 0.0103 0.0093 0.2228
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0712 0.0783 1
Schistosoma mansoni serine protease inhibitors serpins 0.0029 0.001 0.0003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2161 0.2421 0.3957
Treponema pallidum 76K protein 0.003 0.001 0.5
Brugia malayi Probable ATP-dependent helicase DHX35 0.0034 0.0015 0.0012
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Onchocerca volvulus 0.0039 0.0022 0.0318
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0019
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0062 0.0048 0.0041
Brugia malayi serpin 0.0029 0.001 0.0007
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0296 0.0312 0.0382
Schistosoma mansoni cathepsin D (A01 family) 0.0036 0.0018 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0391 0.0419 0.0676
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0103 0.0093 0.0087
Echinococcus granulosus sodium:glucose cotransporter 0.0296 0.0312 0.0305
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0105 0.0096 0.0089
Schistosoma mansoni chromatin regulatory protein sir2 0.0105 0.0096 0.0089
Echinococcus granulosus collagen alpha 1VII chain 0.003 0.001 0.0004
Schistosoma mansoni c4b-binding protein beta chain 0.0039 0.0022 0.0015
Toxoplasma gondii subtilisin SUB4 0.0391 0.0419 1
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0084 0.0077
Echinococcus multilocularis Estrogen regulated protein EP45 0.0029 0.001 0.0004
Plasmodium vivax subtilisin-like protease 2, putative 0.0391 0.0419 0.9514
Brugia malayi angiogenesis inhibito 0.0025 0.0006 0.0003
Onchocerca volvulus 0.0029 0.001 0.0121
Echinococcus multilocularis tissue type plasminogen activator 0.0031 0.0012 0.0007
Brugia malayi hypothetical protein 0.0098 0.0087 0.0085
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0004
Plasmodium falciparum subtilisin-like protease 1 0.0391 0.0419 0.9514
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0006 0.015
Echinococcus multilocularis integrin alpha 3 0.0573 0.0624 0.0773
Brugia malayi serpin precursor 0.0029 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0036 0.0018 0.0015
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0391 0.0419 1
Onchocerca volvulus 0.0031 0.0012 0.0163
Toxoplasma gondii histone deacetylase SIR2 0.0105 0.0096 0.2171
Brugia malayi EGF-like domain containing protein 0.0091 0.008 0.0077
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.5422 0.6108 1
Loa Loa (eye worm) sirtuin 4 0.0105 0.0096 0.0093
Loa Loa (eye worm) hypothetical protein 0.0076 0.0063 0.006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0004
Echinococcus multilocularis epidermal growth factor receptor 0.0631 0.0691 0.0856
Brugia malayi Furin-like cysteine rich region family protein 0.0631 0.0691 0.0688
Chlamydia trachomatis protoporphyrinogen oxidase 0.0103 0.0093 1
Brugia malayi SWIRM domain containing protein 0.0549 0.0598 0.0595
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2161 0.2421 0.3957
Onchocerca volvulus Arrow homolog 0.0026 0.0007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.177 0.1979 0.3232
Onchocerca volvulus 0.0549 0.0598 1
Toxoplasma gondii calcium binding egf domain-containing protein 0.0026 0.0007 0.0016
Loa Loa (eye worm) subtilase 0.0391 0.0419 0.0417
Schistosoma mansoni hypothetical protein 0.0073 0.006 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0249 0.0242
Brugia malayi protein kinase C II. 0.0095 0.0084 0.0081
Toxoplasma gondii subtilisin SUB5 0.0391 0.0419 1
Mycobacterium leprae Probable polyketide synthase Pks1 0.0026 0.0006 0.015
Mycobacterium ulcerans Sir2-like regulatory protein 0.0105 0.0096 0.2288
Leishmania major UDP-galactopyranose mutase 0.0103 0.0093 0.1051
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.052 0.0565 0.0563
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0391 0.0419 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Trichomonas vaginalis hypothetical protein 0.0044 0.0027 0.0034
Echinococcus multilocularis C type lectin domian containing protein 0.0039 0.0022 0.0019
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0391 0.0419 0.0516
Plasmodium falciparum plasmepsin I 0.0036 0.0018 0.0182
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0712 0.0783 0.1271
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0391 0.0419 0.0417
Schistosoma mansoni chromatin regulatory protein sir2 0.0712 0.0783 0.0776
Leishmania major subtilisin-like serine peptidase 0.0391 0.0419 0.5283
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0098 0.0087 0.1003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0019
Brugia malayi endochitinase 0.0073 0.006 0.0057
Brugia malayi GCC2 and GCC3 family protein 0.0059 0.0043 0.0041
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.003 0.001 0.0101
Brugia malayi hypothetical protein 0.0039 0.0022 0.0019
Onchocerca volvulus Putative endochitinase 0.0073 0.006 0.0954
Echinococcus multilocularis c4b binding protein beta chain 0.0039 0.0022 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0391 0.0419 0.0676
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0062 0.0048 0.0866
Schistosoma mansoni chromatin regulatory protein sir2 0.0105 0.0096 0.0089
Onchocerca volvulus 0.003 0.001 0.0129
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0006 0.015
Loa Loa (eye worm) TK/ALK protein kinase 0.0073 0.006 0.0057
Plasmodium falciparum plasmepsin IX 0.0036 0.0018 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Echinococcus granulosus integrin alpha 3 0.0573 0.0624 0.0618
Echinococcus multilocularis 0.7094 0.7999 1
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0105 0.0096 0.2288
Brugia malayi Protein kinase domain containing protein 0.0044 0.0027 0.0025
Brugia malayi hypothetical protein 0.0039 0.0022 0.0019
Onchocerca volvulus 0.0029 0.001 0.0121
Loa Loa (eye worm) CUB domain-containing protein 0.0026 0.0007 0.0004
Loa Loa (eye worm) serpin 0.0029 0.001 0.0007
Mycobacterium ulcerans polyketide synthase 0.0024 0.0005 0.0109
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0019
Plasmodium vivax aspartyl proteinase, putative 0.0036 0.0018 0.0182
Echinococcus granulosus serine protease inhibitor 0.0029 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0019
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0024 0.0005 0.0109
Echinococcus multilocularis membrane bound transcription factor site 1 0.0391 0.0419 0.0516
Entamoeba histolytica hypothetical protein, conserved 0.003 0.001 0.0006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.5422 0.6108 1
Toxoplasma gondii SWIRM domain-containing protein 0.0043 0.0026 0.0466
Echinococcus multilocularis serine:threonine protein kinase N2 0.0087 0.0075 0.0085
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0035 0.0017 0.0012
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0019
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0007 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0391 0.0419 0.0676
Schistosoma mansoni amine oxidase 0.0103 0.0093 0.0087
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.003 0.001 0.0006
Echinococcus multilocularis c Jun NH2 terminal kinase 0.024 0.0249 0.0303
Echinococcus granulosus protein kinase c epsilon type 0.0095 0.0084 0.0077
Echinococcus multilocularis voltage dependent calcium channel subunit 0.003 0.001 0.0004
Echinococcus multilocularis discoidin domain containing receptor 2 0.0044 0.0027 0.0026
Toxoplasma gondii microneme protein MIC2 0.003 0.001 0.0101
Toxoplasma gondii histone deacetylase SIR2-like 0.0105 0.0096 0.2171
Trichomonas vaginalis conserved hypothetical protein 0.177 0.1979 0.3232
Brugia malayi serpin 0.0029 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0091 0.008 0.0077
Brugia malayi Pepsin A precursor 0.0036 0.0018 0.0015
Brugia malayi von Willebrand factor type A domain containing protein 0.003 0.001 0.0008
Echinococcus granulosus integrin alpha ps 0.0509 0.0552 0.0546
Onchocerca volvulus 0.0039 0.0022 0.0318
Echinococcus granulosus lysine specific histone demethylase 1A 0.0103 0.0093 0.0087
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0391 0.0419 1
Leishmania major arginine N-methyltransferase-like protein 0.0062 0.0048 0.0457
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Schistosoma mansoni integrin alpha-ps 0.0294 0.031 0.0303
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0036 0.0018 0.029
Toxoplasma gondii subtilisin SUB10 0.0391 0.0419 1
Trichomonas vaginalis conserved hypothetical protein 0.177 0.1979 0.3232
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0391 0.0419 0.5283
Brugia malayi Sex muscle abnormal protein 5 0.0144 0.014 0.0137
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0018 0.0011
Loa Loa (eye worm) hypothetical protein 0.0146 0.0142 0.0139
Mycobacterium leprae Polyketide synthase Pks13 0.0036 0.0018 0.0433
Echinococcus granulosus protein arginine N methyltransferase 7 0.0035 0.0017 0.001
Echinococcus granulosus serine protease inhibitor 0.0029 0.001 0.0003
Toxoplasma gondii kringle domain-containing protein 0.0031 0.0012 0.015
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0062 0.0048 0.0051
Plasmodium falciparum plasmepsin V 0.041 0.044 1
Plasmodium vivax apical sushi protein, putative 0.0039 0.0022 0.0261
Giardia lamblia Sirtuin type 2 0.0105 0.0096 0.0235
Toxoplasma gondii subtilisin SUB8 0.0391 0.0419 1
Mycobacterium ulcerans polyketide synthase 0.0026 0.0006 0.015
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0035 0.0017 0.0012
Schistosoma mansoni hypothetical protein 0.0214 0.0219 0.0213
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0105 0.0096 0.1033
Brugia malayi von Willebrand Factor 0.003 0.001 0.0008
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0043 0.0026 0.0019
Schistosoma mansoni site-1 peptidase (S08 family) 0.0391 0.0419 0.0413
Schistosoma mansoni serine protease inhibitors serpins 0.0029 0.001 0.0003
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0096 0.0146
Loa Loa (eye worm) DPY-31 protein 0.0026 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0004
Entamoeba histolytica hypothetical protein 0.003 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0041 0.0023 0.002
Echinococcus granulosus integrin alpha ps 0.0214 0.0219 0.0213
Mycobacterium tuberculosis Possible arabinofuranosyltransferase AftD 0.0044 0.0027 0.0654
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0391 0.0419 1
Loa Loa (eye worm) hypothetical protein 0.043 0.0463 0.046
Plasmodium falciparum plasmepsin VIII, putative 0.0036 0.0018 0.0182
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0062 0.0048 0.1002
Onchocerca volvulus 0.003 0.001 0.0129
Schistosoma mansoni septate junction protein 0.0064 0.0049 0.0042
Brugia malayi serpin (BmSERPIN) 0.0029 0.001 0.0007
Plasmodium vivax aspartyl protease, putative 0.0036 0.0018 0.0182
Schistosoma mansoni hypothetical protein 0.003 0.001 0.0004
Giardia lamblia hypothetical protein 0.0091 0.008 0.0192
Echinococcus granulosus sodium:glucose cotransporter 2 0.0296 0.0312 0.0305
Echinococcus granulosus solute carrier family 5 0.0296 0.0312 0.0305
Brugia malayi hypothetical protein 0.0057 0.0041 0.0039
Onchocerca volvulus 0.0039 0.0022 0.0318
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2161 0.2421 0.3957
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0027 0.0394
Schistosoma mansoni hypothetical protein 0.0073 0.006 0.0053
Loa Loa (eye worm) hypothetical protein 0.0073 0.006 0.0057
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0036 0.0018 0.0014
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0024 0.0005 0.0109
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0019
Brugia malayi Fibulin-1 precursor 0.0026 0.0007 0.0004
Brugia malayi CUB domain containing protein 0.0026 0.0007 0.0004
Echinococcus granulosus protein arginine N methyltransferase 8 0.0062 0.0048 0.0041
Schistosoma mansoni hypothetical protein 0.0035 0.0017 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0026 0.0031
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0105 0.0096 0.1084
Echinococcus granulosus discoidin domain containing receptor 2 0.0044 0.0027 0.0021
Echinococcus granulosus discoidin domain containing receptor 2 0.0044 0.0027 0.0021
Brugia malayi hypothetical protein 0.0029 0.001 0.0007
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0096 0.0146
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0712 0.0783 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Trichomonas vaginalis beta-hexosaminidase B, putative 0.0044 0.0027 0.0034
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0074 0.006 0.0053
Loa Loa (eye worm) proprotein convertase 2 0.2161 0.2421 0.2419
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Echinococcus granulosus sodium:myo inositol cotransporter 0.0296 0.0312 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Echinococcus multilocularis protein jagged 2 0.0091 0.008 0.0092
Brugia malayi NAD-dependent deacetylase SIRT1 0.0105 0.0096 0.0093
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0035 0.0017 0.0057
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0105 0.0096 0.1084
Echinococcus multilocularis adam 0.0148 0.0144 0.0172
Brugia malayi Kelch motif family protein 0.0456 0.0493 0.049
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0007 0.0004
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0035 0.0017 0.0057
Onchocerca volvulus 0.0029 0.001 0.0121
Brugia malayi Protein kinase domain containing protein 0.0073 0.006 0.0057
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0026 0.0006 0.015
Loa Loa (eye worm) hypothetical protein 0.0294 0.031 0.0307
Echinococcus granulosus chromatin regulatory protein sir2 0.0712 0.0783 0.0776
Brugia malayi von Willebrand factor type A domain containing protein 0.003 0.001 0.0008
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0712 0.0783 0.0776
Entamoeba histolytica SWIRM domain protein 0.0043 0.0026 0.0201
Entamoeba histolytica hypothetical protein 0.0098 0.0087 0.1003
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0005 0.0109
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Echinococcus granulosus tissue type plasminogen activator 0.0031 0.0012 0.0006
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0417 0.0449 0.567
Echinococcus multilocularis Estrogen regulated protein EP45 0.0029 0.001 0.0004
Toxoplasma gondii subtilisin SUB12 0.0391 0.0419 1
Brugia malayi serpin 0.0029 0.001 0.0007
Echinococcus multilocularis nuclear receptor 2C2 associated protein 0.0044 0.0027 0.0026
Brugia malayi Sushi domain 0.0039 0.0022 0.0019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Toxoplasma gondii serpin (serine proteinase inhibitor) superfamily protein 0.0029 0.001 0.009
Schistosoma mansoni chromatin regulatory protein sir2 0.0712 0.0783 0.0776
Brugia malayi SWIRM domain containing protein 0.0043 0.0026 0.0023
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.003 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Plasmodium falciparum plasmepsin VII 0.0036 0.0018 0.0182
Onchocerca volvulus 0.0039 0.0022 0.0318
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0103 0.0093 0.2228
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0712 0.0783 0.0971
Echinococcus multilocularis integrin alpha ps 0.0214 0.0219 0.0266
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0296 0.0312 0.0382
Loa Loa (eye worm) hypothetical protein 0.0034 0.0015 0.0012
Schistosoma mansoni serine protease inhibitors serpins 0.0029 0.001 0.0003
Entamoeba histolytica hypothetical protein, conserved 0.003 0.001 0.0006
Echinococcus multilocularis collagen alpha 1(VII) chain 0.003 0.001 0.0004
Echinococcus granulosus neuroendocrine convertase 2 0.5603 0.6313 0.631
Echinococcus granulosus serine:threonine protein kinase N2 0.0077 0.0064 0.0058
Brugia malayi hypothetical protein 0.0036 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0091 0.008 0.0077
Plasmodium falciparum plasmepsin VI 0.0036 0.0018 0.0182
Toxoplasma gondii aspartyl protease ASP1 0.0036 0.0018 0.029
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0506 0.0549 0.0543
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0108 0.0099 0.0096
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0053 0.0037 0.0034
Toxoplasma gondii rhoptry neck protein RON9 0.0039 0.0022 0.0373
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0103 0.0093 0.2228
Trichomonas vaginalis conserved hypothetical protein 0.0391 0.0419 0.0676
Toxoplasma gondii protease inhibitor PI1 0.0029 0.001 0.009
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0035 0.0017 0.0057
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0035 0.0017 0.0016
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Echinococcus multilocularis SWI:SNF complex subunit SMARCC2 0.0043 0.0026 0.0023
Brugia malayi Serpin protein 6 0.0029 0.001 0.0007
Onchocerca volvulus 0.0039 0.0022 0.0318
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0035 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0004
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0712 0.0783 0.1271
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0024 0.0005 0.0109
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.5422 0.6108 0.6105
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0029 0.0022
Giardia lamblia Neurogenic locus notch-like protein 0.0091 0.008 0.0192
Echinococcus granulosus Coagulation factor 5 8 type C terminal 0.0044 0.0027 0.0021
Echinococcus multilocularis MAM 0.0073 0.006 0.0066
Schistosoma mansoni hypothetical protein 0.021 0.0214 0.0208
Schistosoma mansoni integrin alpha-ps 0.0447 0.0483 0.0476
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0007
Brugia malayi Nematode astacin protease protein 30 0.0026 0.0007 0.0004
Schistosoma mansoni discoidin domain receptor 0.0044 0.0027 0.0021
Brugia malayi EGF-like domain containing protein 0.0091 0.008 0.0077
Echinococcus multilocularis protein arginine methyltransferase 0.0062 0.0048 0.0051
Schistosoma mansoni btb and poz domain-containing protein 0.0044 0.0027 0.0021
Toxoplasma gondii F5/8 type C domain-containing protein 0.0044 0.0027 0.0511
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0456 0.0493 0.049
Onchocerca volvulus Putative cubilin 0.0045 0.0029 0.0432
Echinococcus granulosus c4b binding protein beta chain 0.0039 0.0022 0.0015
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0024 0.0005 0.0109
Brugia malayi aspartic protease BmAsp-2, identical 0.0036 0.0018 0.0015
Toxoplasma gondii rhoptry neck protein RON1 0.0039 0.0022 0.0373
Echinococcus granulosus discoidin domain receptor 0.0044 0.0027 0.0021
Plasmodium vivax LCCL domain-containing protein 0.0044 0.0027 0.0394
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0018 0.0011
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0076 0.0063 0.007
Schistosoma mansoni growth factor receptor-bound protein 0.0144 0.014 0.0133
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0007 0.0004
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0095 0.0084 0.0081
Mycobacterium ulcerans chitinase/cellulase 0.0062 0.0047 0.1131
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0035 0.0017 0.0089
Loa Loa (eye worm) hypothetical protein 0.0506 0.0549 0.0547
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0105 0.0096 0.1989
Schistosoma mansoni integrin beta subunit 0.1666 0.186 0.1855
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.177 0.1979 0.3232
Echinococcus multilocularis 0.0103 0.0093 0.0108
Echinococcus multilocularis fibrillin 1 0.012 0.0113 0.0132
Plasmodium vivax hypothetical protein, conserved 0.0103 0.0093 0.193
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0096 0.0146
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0004
Plasmodium falciparum cysteine repeat modular protein 1 0.0031 0.0012 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.177 0.1979 0.3232
Loa Loa (eye worm) hypothetical protein 0.8864 1 1
Echinococcus multilocularis protein will die slowly 0.021 0.0214 0.026
Giardia lamblia Hypothetical protein 0.0712 0.0783 0.2114
Loa Loa (eye worm) integrin beta-2 0.2829 0.3175 0.3173
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0035 0.0017 0.0256
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0096 0.0146
Loa Loa (eye worm) CUTiclin-Like family member 0.003 0.001 0.0008
Schistosoma mansoni hypothetical protein 0.0044 0.0027 0.0021
Loa Loa (eye worm) WD40 repeat protein 0.021 0.0214 0.0212
Echinococcus granulosus membrane bound transcription factor site 1 0.0391 0.0419 0.0413
Loa Loa (eye worm) Carm1-pending protein 0.0035 0.0017 0.0014
Brugia malayi hypothetical protein 0.0039 0.0022 0.0019
Loa Loa (eye worm) aspartyl protease 6 0.0036 0.0018 0.0015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Brugia malayi Will die slowly protein 0.021 0.0214 0.0212
Toxoplasma gondii bicoid-interacting protein BIN3 0.0035 0.0017 0.0256
Brugia malayi von Willebrand factor type A domain containing protein 0.003 0.001 0.0008
Onchocerca volvulus 0.0073 0.006 0.0953
Loa Loa (eye worm) hypothetical protein 0.0098 0.0087 0.0085
Mycobacterium leprae Possible secreted protease 0.0391 0.0419 1
Onchocerca volvulus 0.0026 0.0007 0.0069
Loa Loa (eye worm) hypothetical protein 0.0358 0.0382 0.038
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0105 0.0096 0.0111
Toxoplasma gondii hypothetical protein 0.0091 0.008 0.1789
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0007
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0035 0.0017 0.0256
Brugia malayi Eukaryotic aspartyl protease family protein 0.0036 0.0018 0.0015
Plasmodium vivax hypothetical protein, conserved 0.0103 0.0093 0.193
Giardia lamblia High cysteine protein 0.0091 0.008 0.0192
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0005 0.0109
Schistosoma mansoni hypothetical protein 0.177 0.1979 0.1973
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0024 0.0005 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Echinococcus granulosus methyltransferase protein 5 0.0035 0.0017 0.001
Brugia malayi neuroendocrine convertase 1 precursor 0.5603 0.6313 0.6312
Loa Loa (eye worm) serpin 0.0029 0.001 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Entamoeba histolytica PH domain containing protein kinase, putative 0.0077 0.0064 0.0705
Loa Loa (eye worm) hypothetical protein 0.0091 0.008 0.0077
Brugia malayi aspartic protease BmAsp-1, identical 0.0036 0.0018 0.0015
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0062 0.0048 0.0041
Onchocerca volvulus 0.0044 0.0027 0.0414
Onchocerca volvulus 0.0039 0.0022 0.0318
Echinococcus granulosus laminin 0.0026 0.0007 0.0000078166
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0036 0.0018 0.0015
Loa Loa (eye worm) serpin protein 6 0.0029 0.001 0.0007
Brugia malayi hypothetical protein 0.0103 0.0093 0.0091
Schistosoma mansoni protein kinase 0.0123 0.0116 0.011
Brugia malayi Sodium:solute symporter family protein 0.0076 0.0063 0.006
Onchocerca volvulus Putative endochitinase 0.0073 0.006 0.0954
Toxoplasma gondii aspartyl protease ASP3 0.0036 0.0018 0.029
Schistosoma mansoni egf-like domain protein 0.0026 0.0007 0.0000078166
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Onchocerca volvulus 0.003 0.001 0.0129
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0103 0.0093 0.193
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Brugia malayi Lectin C-type domain containing protein 0.0026 0.0007 0.0004
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0096 0.0146
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0712 0.0783 1
Giardia lamblia Furin precursor putative serine protease 0.177 0.1979 0.5387
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0098 0.0087 0.0974
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Echinococcus granulosus C type lectin domian containing protein 0.0039 0.0022 0.0015
Brugia malayi Zona pellucida-like domain containing protein 0.003 0.001 0.0008
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0027 0.0394
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0062 0.0048 0.0067
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0105 0.0096 0.0235
Onchocerca volvulus 0.0029 0.001 0.0121
Echinococcus granulosus growth factor receptor bound protein 2 0.0144 0.014 0.0133
Brugia malayi transcriptional regulator, Sir2 family protein 0.0712 0.0783 0.078
Brugia malayi von Willebrand factor type A domain containing protein 0.003 0.001 0.0008
Schistosoma mansoni sodium/solute symporter 0.0076 0.0063 0.0056
Brugia malayi Zona pellucida-like domain containing protein 0.003 0.001 0.0008
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0096 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0035 0.0017 0.0057
Onchocerca volvulus 0.0391 0.0419 0.6999
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0023 0.0003 0.0066
Loa Loa (eye worm) hypothetical protein 0.0591 0.0645 0.0643
Brugia malayi von Willebrand factor type A domain containing protein 0.003 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0004
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0043 0.0026 0.0024
Brugia malayi transcriptional regulator, Sir2 family protein 0.0105 0.0096 0.0093
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2161 0.2421 0.3957
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0026 0.0006 0.015
Onchocerca volvulus 0.0026 0.0007 0.0069
Loa Loa (eye worm) serpin 0.0029 0.001 0.0007
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0105 0.0096 0.0089
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0105 0.0096 0.1112
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Mycobacterium leprae PROBABLE CONSERVED TRANSMEMBRANE PROTEIN 0.0044 0.0027 0.0654
Plasmodium falciparum plasmepsin II 0.0036 0.0018 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Leishmania major silent information regulator 2, putative 0.0712 0.0783 1
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0039 0.0022 0.0019
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0103 0.0093 0.0091
Echinococcus granulosus MAM 0.0073 0.006 0.0053
Plasmodium falciparum plasmepsin X 0.0036 0.0018 0.0182
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Plasmodium vivax NAD-dependent deacetylase, putative 0.0105 0.0096 0.1989
Echinococcus granulosus Tolloid protein 1 0.0053 0.0037 0.003
Loa Loa (eye worm) hypothetical protein 0.0044 0.0027 0.0025
Brugia malayi transcriptional regulator, Sir2 family protein 0.0105 0.0096 0.0093
Giardia lamblia Neurogenic locus Notch protein precursor 0.0091 0.008 0.0192
Echinococcus multilocularis Coagulation factor 5 8 type, C terminal 0.0044 0.0027 0.0026
Plasmodium falciparum plasmepsin III 0.0036 0.0018 0.0182
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0044 0.0027 0.0034
Mycobacterium ulcerans chitinase/cellulase 0.0062 0.0047 0.1131
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0026 0.0007 0.0004
Giardia lamblia High cysteine protein 0.0091 0.008 0.0192
Schistosoma mansoni chromatin regulatory protein sir2 0.0105 0.0096 0.0089
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0234 0.0241 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Trypanosoma brucei subtilisin peptidase 0.0391 0.0419 0.5256
Schistosoma mansoni inositol transporter 0.0296 0.0312 0.0305
Toxoplasma gondii F5/8 type C domain-containing protein 0.0044 0.0027 0.0511
Loa Loa (eye worm) zinc metalloproteinase toh-2 0.0026 0.0007 0.0004
Entamoeba histolytica elongation factor-2 kinase, putative 0.003 0.001 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0105 0.0096 0.1112
Brugia malayi Integrin alpha pat-2 precursor 0.0805 0.0888 0.0885
Trichomonas vaginalis conserved hypothetical protein 0.177 0.1979 0.3232
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0062 0.0048 0.0866
Toxoplasma gondii subtilisin SUB1 0.0391 0.0419 1
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.003 0.001 0.0008
Echinococcus granulosus epidermal growth factor receptor 0.0631 0.0691 0.0685
Brugia malayi hypothetical protein 0.0029 0.001 0.0007
Plasmodium falciparum plasmepsin IV 0.0036 0.0018 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.177 0.1979 0.3232
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0417 0.0449 0.5645
Plasmodium vivax subtilisin-like protease 1 0.0391 0.0419 0.9514
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0123 0.0116 0.0137
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0026 0.0006 0.015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Schistosoma mansoni discoidin domain receptor 0.0044 0.0027 0.0021
Mycobacterium tuberculosis Conserved hypothetical protein 0.0103 0.0093 0.2228
Loa Loa (eye worm) hypothetical protein 0.0549 0.0598 0.0595
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0103 0.0093 0.193
Schistosoma mansoni amine oxidase 0.0103 0.0093 0.0087
Leishmania major sir2-family protein-like protein 0.0105 0.0096 0.1084
Schistosoma mansoni serpin 0.0029 0.001 0.0003
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0062 0.0048 0.0067
Loa Loa (eye worm) microfilarial chitinase 0.0062 0.0047 0.0045
Toxoplasma gondii F5/8 type C domain-containing protein 0.0044 0.0027 0.0511
Echinococcus granulosus fibrillin 1 0.0094 0.0083 0.0076
Schistosoma mansoni integrin alpha 0.0805 0.0888 0.0881
Schistosoma mansoni chromatin regulatory protein sir2 0.0105 0.0096 0.0089
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0036 0.0018 0.029
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0007
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0062 0.0048 0.0067
Loa Loa (eye worm) hypothetical protein 0.0062 0.0047 0.0044
Echinococcus multilocularis protein kinase c epsilon type 0.0095 0.0084 0.0097
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Brugia malayi von Willebrand factor type A domain containing protein 0.003 0.001 0.0008
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0076 0.0063 0.1363
Brugia malayi hypothetical protein 0.0026 0.0007 0.0004
Mycobacterium tuberculosis Possible chitinase 0.0062 0.0047 0.1131
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.001 0.0008
Brugia malayi hypothetical protein 0.043 0.0463 0.046
Echinococcus granulosus Estrogen regulated protein EP45 0.0029 0.001 0.0003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0029 0.0022
Schistosoma mansoni hypothetical protein 0.0031 0.0012 0.0006
Echinococcus granulosus Estrogen regulated protein EP45 0.0029 0.001 0.0003
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0024 0.0005 0.0109
Brugia malayi Subtilase family protein 0.0391 0.0419 0.0417
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0008
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0057 0.0041 0.0035
Echinococcus multilocularis fibrillin 2 0.0091 0.008 0.0092
Echinococcus multilocularis serine protease inhibitor 0.0029 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0045 0.0029 0.0026
Echinococcus multilocularis integrin alpha ps 0.0447 0.0483 0.0595
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.024 0.0249 0.0246
Brugia malayi ADAMTS-like protease 0.0025 0.0006 0.0003
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0024 0.0005 0.0002
Brugia malayi BmSERPIN 0.0029 0.001 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2161 0.2421 0.3957
Schistosoma mansoni protein arginine n-methyltransferase 0.0035 0.0017 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Toxoplasma gondii histone lysine-specific demethylase 0.0103 0.0093 0.2109
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0391 0.0419 0.0413
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0036 0.0018 0.0011
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0035 0.0017 0.0016
Onchocerca volvulus 0.0029 0.001 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0027 0.0034
Brugia malayi serpin 0.0029 0.001 0.0007
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0391 0.0419 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0391 0.0419 0.0676
Brugia malayi Suppressor of lurcher protein 1 precursor 0.0026 0.0007 0.0004
Echinococcus multilocularis integrin beta 2 0.2095 0.2346 0.2927
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0046 0.0029 0.0026
Onchocerca volvulus 0.0091 0.008 0.13
Mycobacterium ulcerans polyketide synthase Pks13 0.0036 0.0018 0.0433
Onchocerca volvulus 0.0036 0.0018 0.026
Giardia lamblia Transcriptional regulator, Sir2 family 0.0105 0.0096 0.0235
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0391 0.0419 1
Echinococcus granulosus protein arginine methyltransferase 0.0062 0.0048 0.0041
Plasmodium vivax plasmepsin IV, putative 0.0036 0.0018 0.0182
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0391 0.0419 1
Echinococcus granulosus fibrillin 2 0.0091 0.008 0.0073
Loa Loa (eye worm) hypothetical protein 0.0276 0.0289 0.0286
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0105 0.0096 0.0146
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0091 0.008 0.012
Loa Loa (eye worm) hypothetical protein 0.0049 0.0032 0.0029
Trichomonas vaginalis WD repeat domain, putative 0.021 0.0214 0.034
Onchocerca volvulus 0.003 0.001 0.0129
Plasmodium vivax aspartyl protease, putative 0.0036 0.0018 0.0182
Trypanosoma cruzi UDP-galactopyranose mutase 0.0103 0.0093 0.1051

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 19.6 mg kg-1 Inhibition against writhing induced by Phenylbenzoquinone in male swiss albino mice ChEMBL. 3263504
ED50 (functional) = 19.6 mg kg-1 Inhibition against writhing induced by Phenylbenzoquinone in male swiss albino mice ChEMBL. 3263504
IC50 (functional) = 0.00000005 M Inhibitory activity against prostaglandin biosynthesis in stimulated chondrocyte cell culture ChEMBL. 3263504
Inhibition (functional) = 11.1 % Inhibition against adjuvant-induced paw edema at a dose of 25 mg/kg in male Sprague-Dawley rats. ChEMBL. 3263504
logP (ADMET) = 5.2 Partition coefficient (logP) ChEMBL. 3263504

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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