Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.4678 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.2667 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.2667 | 0.6023 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.2667 | 0.2628 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.2667 | 0.5651 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.1969 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0199 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.1969 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.2667 | 0.6023 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.1969 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.4393 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.1969 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.2667 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0109 | 0.0056 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.2667 | 0.2628 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.2667 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.1916 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.4393 | 0.4363 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.1969 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.2667 | 1 |
Trichomonas vaginalis | sphingomyelinase C 2 precursor, putative | 0.0004 | 0.0053 | 0.0199 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.8867 | 1 |
Trichomonas vaginalis | type IV inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.1969 |
Onchocerca volvulus | 0.0028 | 0.4393 | 1 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.1969 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0584 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.2667 | 0.5 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0525 | 0.1969 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.2667 | 1 |
Trichomonas vaginalis | ocrl type II inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0525 | 0.1969 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.2667 | 0.2966 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.2667 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.1969 |
Trichomonas vaginalis | type II inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0525 | 0.1969 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.1916 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0634 | 0.1257 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.2667 | 1 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.4678 | 1 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.2667 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4678 | 0.465 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0634 | 0.1257 |
Trichomonas vaginalis | skeletal muscle/kidney enriched inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0939 | 0.2042 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.1969 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0634 | 0.1257 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.2667 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.1969 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.1969 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.2667 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4678 | 0.465 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0634 | 0.1257 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.2667 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.2667 | 0.5651 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.092 | 0.1996 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.1969 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.2667 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.1969 |
Trichomonas vaginalis | Phospholipase C precursor, putative | 0.0004 | 0.0053 | 0.0199 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.4393 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.2667 | 1 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0199 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0199 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.