Detailed information for compound 113064

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 810.964 | Formula: C42H66O15
  • H donors: 10 H acceptors: 11 LogP: 1.05 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 4
  • SMILES: OCC1OC(OC2C(O)C(OC(C2O)C)O[C@@H]2CC[C@@]3(C([C@@]2(C)CO)CC[C@]2(C3C=CC3=C4C[C@@](C)(CC[C@]4([C@H](C[C@@]23C)O)CO)C(=O)O)C)C)C(C(C1O)O)O
  • InChi: 1S/C42H66O15/c1-20-28(47)33(57-34-31(50)30(49)29(48)23(17-43)55-34)32(51)35(54-20)56-27-10-11-38(3)24(39(27,4)18-44)9-12-40(5)25(38)8-7-21-22-15-37(2,36(52)53)13-14-42(22,19-45)26(46)16-41(21,40)6/h7-8,20,23-35,43-51H,9-19H2,1-6H3,(H,52,53)/t20?,23?,24?,25?,26-,27+,28?,29?,30?,31?,32?,33?,34?,35?,37-,38+,39+,40-,41-,42-/m1/s1
  • InChiKey: ZZPLELRHPJGMIH-UHDVSCSZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.023 0.0805 0.496
Brugia malayi Nuclear hormone receptor-like 1 0.0164 0.0556 0.0727
Loa Loa (eye worm) hypothetical protein 0.0453 0.1653 0.2155
Mycobacterium ulcerans esterase/lipase LipP 0.0116 0.0372 0.2254
Brugia malayi nuclear receptor NHR-88 0.0078 0.0227 0.0296
Schistosoma mansoni nuclear receptor nhr-48 0.0078 0.0227 0.0623
Mycobacterium leprae putative cytochrome p450 0.0147 0.0492 0.6262
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.023 0.0804 0.315
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0164 0.0553 0.0546
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.023 0.0804 0.315
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0684 0.2527 1
Loa Loa (eye worm) CYP4Cod1 0.023 0.0805 0.1046
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0048 0.0227
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Brugia malayi beta-lactamase 0.0116 0.0372 0.0486
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0021 0.0013 0.0035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus granulosus dnaJ subfamily B 0.091 0.3387 0.7071
Mycobacterium leprae Conserved hypothetical protein 0.0147 0.0492 0.6262
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0021 0.0012 0.0004
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0079 0.0231 0.1411
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Schistosoma mansoni nuclear hormone receptor 0.0078 0.0227 0.0623
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0013 0.0035
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0147 0.0492 0.1759
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Schistosoma mansoni coup transcription factor 0.0164 0.0556 0.1529
Loa Loa (eye worm) glutathione reductase 0.0088 0.0266 0.0341
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0164 0.0556 0.0721
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0079 0.0231 0.0871
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0013 0.0035
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0021 0.0012 0.0017
Loa Loa (eye worm) steroid hormone receptor 0.0164 0.0556 0.0721
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0021 0.0012 0.0004
Plasmodium vivax glutathione reductase, putative 0.0088 0.0266 0.1012
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0142 0.0472 0.1297
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Brugia malayi hypothetical protein 0.0078 0.0227 0.0296
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0078 0.0227 0.0219
Onchocerca volvulus 0.0021 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0976 0.3637 0.4752
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0021 0.0012 0.0009
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0021 0.0012 0.0015
Echinococcus multilocularis lamin dm0 0.0976 0.3637 0.3633
Toxoplasma gondii thioredoxin reductase 0.0088 0.0266 0.1012
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0048 0.166
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.023 0.0804 0.0797
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0019 0.0005 0.0007
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0021 0.0013 0.0035
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.0005
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0147 0.0492 0.3003
Echinococcus granulosus retinol dehydrogenase 11 0.0021 0.0012 0.0009
Brugia malayi MAP kinase sur-1 0.0056 0.0146 0.0191
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0147 0.0492 0.3003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Brugia malayi ecdysone receptor 0.0078 0.0227 0.0296
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0021 0.0013 0.0035
Onchocerca volvulus 0.0504 0.1844 0.5062
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi Dehydrogenases, short chain protein 30 0.0021 0.0012 0.0015
Brugia malayi hypothetical protein 0.0078 0.0227 0.0296
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0142 0.0472 0.183
Schistosoma mansoni cpg binding protein 0.0064 0.0175 0.0481
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Onchocerca volvulus Protein ultraspiracle homolog 0.0164 0.0556 0.1517
Brugia malayi intermediate filament protein 0.0976 0.3637 0.4756
Onchocerca volvulus 0.0021 0.0012 0.0017
Brugia malayi ubiquitin specific protease 14 0.0021 0.0013 0.0017
Echinococcus multilocularis transcription factor Dp 1 0.0082 0.0245 0.0238
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0523 0.1917 0.2501
Brugia malayi Retinol dehydrogenase 12 0.0021 0.0012 0.0015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0116 0.0372 0.1023
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0146 0.0536
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.0005
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0017 0.0022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.0372 0.1433
Schistosoma mansoni retinal dehydrogenase 0.0021 0.0012 0.0032
Echinococcus multilocularis tumor protein p63 0.0681 0.2519 0.2513
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0021 0.0013 0.0011
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0184 0.063 0.0817
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0146 0.0536
Brugia malayi photoreceptor-specific nuclear receptor 0.0164 0.0556 0.0727
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0048 0.0145
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0067 0.0088
Trypanosoma brucei trypanothione reductase 0.0088 0.0266 0.1012
Echinococcus multilocularis lamin 0.0976 0.3637 0.3633
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Loa Loa (eye worm) DR-78 0.0078 0.0227 0.029
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0008
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0116 0.0372 0.132
Leishmania major protein kinase, putative 0.0684 0.2527 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0116 0.0372 0.2254
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0147 0.0492 0.1759
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0021 0.0012 0.0032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.039 0.2365
Brugia malayi MH2 domain containing protein 0.0258 0.091 0.119
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi hypothetical protein 0.0021 0.0013 0.0017
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0021 0.0013 0.0035
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0164 0.0556 0.0727
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0147 0.0492 0.1759
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0164 0.0556 0.0727
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0078 0.0227 0.0623
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0021 0.0013 0.0005
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0147 0.0492 0.3003
Brugia malayi glutathione reductase 0.0088 0.0266 0.0348
Echinococcus multilocularis dnaJ subfamily B 0.091 0.3387 0.3382
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) oxidoreductase 0.0021 0.0012 0.0008
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Trypanosoma brucei protein kinase, putative 0.0056 0.0146 0.0536
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0048 0.0145
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0017 0.0022
Schistosoma mansoni cytochrome P450 0.0147 0.0492 0.1352
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0012 0.0032
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0147 0.0492 0.3003
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0013 0.0005
Echinococcus multilocularis Protein lozenge 0.0063 0.0172 0.0165
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0164 0.0553 0.2153
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0164 0.0556 0.1149
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.023 0.0805 0.1046
Onchocerca volvulus 0.0021 0.0013 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.0013 0.0005
Brugia malayi cytoplasmic intermediate filament protein 0.0523 0.1917 0.2507
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0147 0.0492 0.191
Echinococcus granulosus Nuclear hormone receptor HR96 0.0078 0.0227 0.0459
Brugia malayi nuclear hormone receptor 0.0164 0.0556 0.0727
Plasmodium falciparum protein serine/threonine kinase-1 0.0684 0.2527 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Schistosoma mansoni retinoic acid receptor RXR 0.0164 0.0556 0.1529
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0164 0.0556 0.1529
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.023 0.0804 0.315
Onchocerca volvulus 0.0021 0.0012 0.0017
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0048 0.0145
Loa Loa (eye worm) hypothetical protein 0.0678 0.2505 0.3271
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.0372 0.1433
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0019 0.0005 0.0007
Trypanosoma cruzi cytochrome P450, putative 0.023 0.0805 0.3155
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0684 0.2527 1
Entamoeba histolytica hypothetical protein 0.0021 0.0013 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.023 0.0804 0.315
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0021 0.0013 0.0011
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Plasmodium falciparum ubiquitin specific protease, putative 0.0021 0.0013 0.0005
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0169 0.0575 0.2239
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0021 0.0013 0.0005
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.0005
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0142 0.0472 0.0611
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0048 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis penicillin-binding protein, putative 0.0116 0.0372 0.1433
Loa Loa (eye worm) hypothetical protein 0.0164 0.0556 0.0721
Onchocerca volvulus 0.0116 0.0372 0.101
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0142 0.0472 0.2963
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0223 0.0779 0.281
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.0005
Echinococcus multilocularis steroid dehydrogenase 0.0021 0.0012 0.0004
Schistosoma mansoni survival motor neuron protein 0.0261 0.0923 0.2536
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0142 0.0472 0.183
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0116 0.0372 0.132
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0021 0.0012 0.0017
Schistosoma mansoni lamin 0.0976 0.3637 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0078 0.0227 0.0296
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0147 0.0492 0.3003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0021 0.0012 0.0015
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.0392 0.1512
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0684 0.2527 1
Onchocerca volvulus 0.0976 0.3637 1
Schistosoma mansoni cpg binding protein 0.0068 0.0189 0.0519
Schistosoma mansoni cellular tumor antigen P53 0.01 0.0311 0.0854
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0164 0.0553 0.2153
Leishmania major protein kinase, putative 0.0169 0.0575 0.2239
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0147 0.0492 0.191
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0147 0.0492 0.1759
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0048 0.0145
Mycobacterium tuberculosis Probable reductase 0.0201 0.0694 0.2498
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0008
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0021 0.0013 0.0035
Echinococcus multilocularis oxidoreductase 0.0021 0.0012 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0079 0.0231 0.0871
Schistosoma mansoni single-minded 0.0606 0.2232 0.6137
Brugia malayi exodeoxyribonuclease III family protein 0.0079 0.0231 0.0302
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0021 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Loa Loa (eye worm) hypothetical protein 0.0052 0.013 0.0163
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0121 0.039 0.1504
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0021 0.0013 0.0011
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0048 0.0132
Onchocerca volvulus 0.0116 0.0372 0.101
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0021 0.0013 0.0011
Trichomonas vaginalis esterase, putative 0.0116 0.0372 0.1433
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0159 0.0535 0.6826
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.0005
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0146 0.0536
Leishmania major protein kinase, putative 0.0173 0.059 0.2299
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.039 0.2365
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.1167 0.4592
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0116 0.0372 0.0486
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0201 0.0694 0.8892
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0021 0.0013 0.0011
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0021 0.0013 0.0035
Loa Loa (eye worm) hypothetical protein 0.0164 0.0556 0.0721
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0164 0.0556 0.1517
Loa Loa (eye worm) hypothetical protein 0.0116 0.0372 0.048
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.001
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0261 0.0923 0.1206
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0021 0.0013 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0021 0.0012 0.0017
Leishmania major cytochrome p450-like protein 0.0147 0.0492 0.191
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0021 0.0013 0.0005
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0147 0.0492 0.3003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0164 0.0556 0.0727
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0078 0.0227 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0164 0.0556 0.0727
Echinococcus multilocularis nuclear receptor nhr 48 0.0078 0.0227 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0164 0.0556 0.0727
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0164 0.0556 0.0721
Loa Loa (eye worm) hypothetical protein 0.0083 0.0245 0.0314
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0504 0.1844 0.2406
Loa Loa (eye worm) cytochrome P450 family protein 0.023 0.0805 0.1046
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0079 0.0231 0.0467
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.1167 0.4592
Brugia malayi ecdysteroid receptor 0.0164 0.0556 0.0727
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0021 0.0013 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi Nuclear hormone receptor E75 0.0078 0.0227 0.0296
Schistosoma mansoni intermediate filament proteins 0.0976 0.3637 1
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0164 0.0553 0.2153
Brugia malayi hypothetical protein 0.043 0.1565 0.2047
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0164 0.0553 0.2153
Echinococcus granulosus tumor protein p63 0.0681 0.2519 0.5254
Echinococcus granulosus survival motor neuron protein 1 0.1279 0.4787 1
Echinococcus granulosus steroid dehydrogenase 0.0021 0.0012 0.0009
Echinococcus multilocularis transfer RNA-Lys 0.0442 0.1611 0.1605
Schistosoma mansoni thyroid hormone receptor 0.0164 0.0556 0.1529
Schistosoma mansoni thyroid hormone receptor 0.0164 0.0556 0.1529
Echinococcus granulosus lamin 0.0976 0.3637 0.7594
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0147 0.0492 0.3003
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0201 0.0694 0.2498
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0021 0.0013 0.0005
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0142 0.0472 0.183
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0008
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0164 0.0556 0.0549
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0142 0.0472 0.0465
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0021 0.0012 0.0032
Schistosoma mansoni peptidase 0.0027 0.0034 0.0094
Brugia malayi Nuclear hormone receptor-like 1 0.0087 0.0262 0.0342
Echinococcus multilocularis thyroid hormone receptor alpha 0.0164 0.0556 0.0549
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0048 0.0145
Brugia malayi hypothetical protein 0.2033 0.7648 1
Echinococcus granulosus ecdysone induced protein 78C 0.0164 0.0556 0.1149
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0147 0.0492 0.3003
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.023 0.0804 0.1666
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.023 0.0804 0.315
Leishmania major hypothetical protein, conserved 0.0116 0.0372 0.1433
Giardia lamblia Hypothetical protein 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.001
Brugia malayi nuclear receptor NHR-67 0.0078 0.0227 0.0296
Trypanosoma cruzi trypanothione reductase, putative 0.0088 0.0266 0.1012
Mycobacterium ulcerans putative regulatory protein 0.0442 0.1611 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0223 0.0779 0.281
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Loa Loa (eye worm) nuclear hormone receptor 0.0078 0.0227 0.029
Loa Loa (eye worm) hypothetical protein 0.0958 0.357 0.4664
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0164 0.0556 0.0727
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0684 0.2527 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0078 0.0227 0.0459
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0008
Onchocerca volvulus 0.0021 0.0012 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0048 0.0145
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0048 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0146 0.0139
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0048 0.0145
Schistosoma mansoni steroid hormone receptor ad4bp 0.0164 0.0556 0.1529
Trichomonas vaginalis adenylate cyclase, putative 0.0164 0.0553 0.2153
Leishmania major trypanothione reductase 0.0088 0.0266 0.1012
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0012 0.0009
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Brugia malayi hypothetical protein 0.0021 0.0012 0.0015
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0021 0.0012 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.0372 0.1433
Schistosoma mansoni zinc finger protein 0.0078 0.0227 0.0623
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.023 0.0804 0.221
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0223 0.0779 0.281
Echinococcus granulosus lamin dm0 0.0976 0.3637 0.7594
Schistosoma mansoni nuclear hormone receptor 0.0078 0.0227 0.0623
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0021 0.0013 0.0005
Mycobacterium ulcerans hypothetical protein 0.0116 0.0372 0.2254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi cytochrome P450 0.0147 0.0492 0.0643
Echinococcus multilocularis retinol dehydrogenase 11 0.0021 0.0012 0.0004
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Leishmania major cytochrome p450-like protein 0.0147 0.0492 0.191
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0147 0.0492 0.3003
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0684 0.2527 0.3299
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.0553 0.2153
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0183 0.0626 0.171
Schistosoma mansoni hypothetical protein 0.043 0.1565 0.4304
Onchocerca volvulus 0.0116 0.0372 0.101
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0012 0.0004
Brugia malayi CXXC zinc finger family protein 0.0064 0.0175 0.0229
Toxoplasma gondii aldehyde dehydrogenase 0.0121 0.039 0.1504
Echinococcus granulosus cytochrome P450 2K1 0.0147 0.0492 0.1014
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.0013 0.0005
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0136 0.0447 0.1228
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0121 0.039 0.1072
Echinococcus multilocularis conserved hypothetical protein 0.0021 0.0012 0.0004
Loa Loa (eye worm) hypothetical protein 0.0116 0.0372 0.048
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0147 0.0492 0.1759
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0021 0.0013 0.0005
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0146 0.0536
Plasmodium vivax serine/threonine kinase-1, putative 0.0684 0.2527 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0013 0.0011
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0471 0.172 0.3584
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0147 0.0492 0.1759
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0147 0.0492 0.1759
Giardia lamblia DUB-1 0.0021 0.0013 0.0005
Brugia malayi Cytochrome P450 family protein 0.0388 0.1406 0.1839
Schistosoma mansoni carbonyl reductase 0.0021 0.0012 0.0032
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0164 0.0556 0.0549
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Giardia lamblia Fructose-bisphosphate aldolase 0.0325 0.1167 0.4592
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0147 0.0492 0.1759
Trichomonas vaginalis guanylate cyclase, putative 0.0164 0.0553 0.2153
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0087 0.0262 0.0255
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Brugia malayi nuclear receptor NHR-88 0.0164 0.0556 0.0727
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Brugia malayi Protein kinase domain containing protein 0.0684 0.2527 0.3304
Brugia malayi Nuclear hormone receptor-like 1 0.0087 0.0262 0.0342
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0169 0.0575 0.2239
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0021 0.0013 0.0005
Echinococcus multilocularis retinol dehydrogenase 11 0.0021 0.0012 0.0004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) transcription factor SMAD2 0.0258 0.091 0.1184
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0079 0.0231 0.0871
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Loa Loa (eye worm) CXXC zinc finger family protein 0.0064 0.0175 0.0222
Brugia malayi oxidoreductase 0.0021 0.0012 0.0015
Trichomonas vaginalis ap endonuclease, putative 0.0079 0.0231 0.0871
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0164 0.0556 0.1149
Loa Loa (eye worm) intermediate filament protein 0.0976 0.3637 0.4752
Brugia malayi N-terminal motif family protein 0.0184 0.063 0.0824
Brugia malayi conserved hypotetical protein 0.0078 0.0227 0.0296
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0012 0.0032
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0147 0.0492 0.1759
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0048 0.0145
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.0005
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0021 0.0013 0.0005
Echinococcus granulosus retinol dehydrogenase 11 0.0021 0.0012 0.0009
Echinococcus multilocularis ecdysone induced protein 78C 0.0164 0.0556 0.0549
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0159 0.0535 0.1918
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Brugia malayi nuclear receptor RXR 0.0087 0.0262 0.0342
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0021 0.0013 0.0005
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0147 0.0492 0.1759
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0012 0.0032
Toxoplasma gondii ABC1 family protein 0.0116 0.0372 0.1433
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Probable lipase LipE 0.0116 0.0372 0.132
Echinococcus granulosus ubiquitin specific protease 41 0.023 0.0804 0.1666
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0048 0.0145
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0021 0.0012 0.0004
Schistosoma mansoni cpg binding protein 0.0068 0.0189 0.0519
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0684 0.2527 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0164 0.0556 0.0721
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.0005
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0021 0.0012 0.0017
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0021 0.0013 0.0005
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0012 0.0032
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0048 0.0145
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0164 0.0553 0.2153
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0048 0.0145
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0146 0.0402
Echinococcus granulosus single minded 2 0.0442 0.1611 0.3356
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0021 0.0012 0.0004
Mycobacterium tuberculosis Conserved protein 0.0116 0.0372 0.132
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0147 0.0492 0.3003
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0164 0.0553 0.1142
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0013 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0146 0.0536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.023 0.0804 0.1666
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0147 0.0492 0.3003
Loa Loa (eye worm) hypothetical protein 0.0087 0.0262 0.0336
Brugia malayi bHLH-PAS transcription factor 0.0442 0.1611 0.2107
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0146 0.0291
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0021 0.0013 0.0035
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0116 0.0372 0.1023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0048 0.0145
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0021 0.0013 0.0035
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0147 0.0492 0.1759
Brugia malayi hypothetical protein 0.0087 0.0262 0.0342
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0164 0.0556 0.0721
Brugia malayi hypothetical protein 0.0019 0.0005 0.0007
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0048 0.0227
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Entamoeba histolytica hypothetical protein 0.043 0.1565 1
Onchocerca volvulus 0.0021 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0116 0.0372 0.048
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0079 0.0231 1
Plasmodium vivax ubiquitin specific protease, putative 0.0021 0.0013 0.0005
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0146 0.0536
Loa Loa (eye worm) hypothetical protein 0.2033 0.7648 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0146 0.0536
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.043 0.1565 0.326
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0147 0.0492 0.3003
Brugia malayi Nuclear hormone receptor E75 0.0078 0.0227 0.0296
Loa Loa (eye worm) hypothetical protein 0.023 0.0804 0.1045
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0164 0.0556 0.0727
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0164 0.0556 0.0721
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0021 0.0013 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.0553 0.2153
Loa Loa (eye worm) MH2 domain-containing protein 0.0258 0.091 0.1184
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0048 0.0085
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0325 0.1167 0.7433
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0012 0.0032
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0079 0.0231 0.0871
Schistosoma mansoni hypothetical protein 0.0147 0.0492 0.1352
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0164 0.0556 0.1149
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) cytochrome P450 0.0147 0.0492 0.0637
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0164 0.0556 0.1529
Onchocerca volvulus 0.0021 0.0012 0.0017
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0147 0.0492 0.3003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0012 0.0009
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0021 0.0013 0.0035
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0048 0.0145
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0048 0.0145
Brugia malayi Intermediate filament tail domain containing protein 0.0976 0.3637 0.4756
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0021 0.0013 0.0035
Loa Loa (eye worm) hypothetical protein 0.0087 0.0262 0.0336
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0164 0.0556 0.0727
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0164 0.0556 0.0727
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0164 0.0556 0.1529
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0021 0.0013 0.0005
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0021 0.0013 0.0035
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi beta-lactamase family protein 0.0116 0.0372 0.0486
Entamoeba histolytica hypothetical protein 0.043 0.1565 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0116 0.0372 0.132
Leishmania major protein kinase, putative 0.0684 0.2527 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.023 0.0804 0.5099
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0147 0.0492 0.3003
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0021 0.0012 0.0017
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0147 0.0492 0.3003
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0021 0.0013 0.0035
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0121 0.039 0.1385
Trypanosoma cruzi cytochrome P450, putative 0.023 0.0805 0.3155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.1167 0.4592
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0021 0.0013 0.0011
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0021 0.0013 0.0005
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0183 0.0626 0.0812
Schistosoma mansoni hypothetical protein 0.091 0.3387 0.9312
Loa Loa (eye worm) histone methyltransferase 0.002 0.0007 0.0003
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0164 0.0556 0.1149
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0201 0.0694 0.2498
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0142 0.0472 0.183
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Schistosoma mansoni nuclear receptor 0.0078 0.0227 0.0623
Echinococcus multilocularis ubiquitin specific protease 41 0.023 0.0804 0.0797
Leishmania major cytochrome p450-like protein 0.023 0.0805 0.3155
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) dehydrogenase 0.0021 0.0012 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Mycobacterium ulcerans beta-lactamase 0.0116 0.0372 0.2254
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0048 0.0063
Schistosoma mansoni carbonyl reductase 0.0021 0.0012 0.0032
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0159 0.0535 0.3274
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0164 0.0556 0.1529
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Loa Loa (eye worm) hypothetical protein 0.0087 0.0262 0.0336
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0021 0.0012 0.0017
Brugia malayi nuclear hormone receptor 0.0078 0.0227 0.0296
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0048 0.0145
Loa Loa (eye worm) oxidoreductase 0.0021 0.0012 0.0008
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0078 0.0227 0.0609
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0021 0.0012 0.0004
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0164 0.0553 0.2153
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0012 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0164 0.0556 0.0727
Brugia malayi nuclear receptor RXR 0.0078 0.0227 0.0296
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0012 0.0009
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0006 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0147 0.0492 0.1759
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0021 0.0012 0.0008
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0021 0.0013 0.0035
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0147 0.0492 0.3003
Schistosoma mansoni lozenge 0.0063 0.0172 0.0473
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.013 0.0163
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0164 0.0556 0.1529
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0078 0.0227 0.0219
Brugia malayi hypothetical protein 0.0087 0.0262 0.0342
Toxoplasma gondii ubiquitin-specific protease USP4 0.0021 0.0013 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0147 0.0492 0.191
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0146 0.0291
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0164 0.0556 0.0727
Brugia malayi beta-lactamase family protein 0.0116 0.0372 0.0486
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0008
Echinococcus multilocularis expressed protein 0.0021 0.0013 0.0005
Schistosoma mansoni hypothetical protein 0.0021 0.0013 0.0035
Mycobacterium leprae Possible regulatory protein 0.0164 0.0553 0.7061
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Echinococcus multilocularis beta LACTamase domain containing family member 0.0116 0.0372 0.0365
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0164 0.0556 0.0549
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0036 0.0067 0.0081
Brugia malayi Thioredoxin reductase 0.0088 0.0266 0.0348
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis ubiquitin specific protease, putative 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus multilocularis 0.0678 0.2505 0.25
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0048 0.166
Loa Loa (eye worm) runx1 0.0063 0.0172 0.0218
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Onchocerca volvulus Bile acid receptor homolog 0.0164 0.0556 0.1517
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0684 0.2527 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0201 0.0694 0.2498
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Schistosoma mansoni ap endonuclease 0.0079 0.0231 0.0634
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Echinococcus multilocularis cpg binding protein 0.0068 0.0189 0.0182
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus granulosus transcription factor Dp 1 0.0082 0.0245 0.0497
Echinococcus granulosus cpg binding protein 0.0068 0.0189 0.0379
Mycobacterium tuberculosis Probable dehydrogenase 0.0201 0.0694 0.2498
Brugia malayi steroid hormone receptor 0.0164 0.0556 0.0727
Brugia malayi tailless protein 0.0078 0.0227 0.0296
Brugia malayi dehydrogenases, short chain protein 2 0.0021 0.0012 0.0015
Loa Loa (eye worm) hypothetical protein 0.01 0.0311 0.04
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Echinococcus multilocularis dual specificity protein kinase clk2 0.0684 0.2527 0.2522
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0012 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0146 0.0536
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0146 0.0139
Mycobacterium tuberculosis Conserved protein 0.0116 0.0372 0.132
Loa Loa (eye worm) hypoxia-induced factor 1 0.185 0.6954 0.9092
Toxoplasma gondii hypothetical protein 0.0021 0.0013 0.0005
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) oxidoreductase 0.0021 0.0012 0.0008
Toxoplasma gondii cytochrome p450 superfamily protein 0.0147 0.0492 0.191
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0048 0.0145
Brugia malayi dehydrogenases, short chain protein 9 0.0021 0.0012 0.0015
Plasmodium falciparum thioredoxin reductase 0.003 0.0048 0.0145
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Brugia malayi PAS domain containing protein 0.0606 0.2232 0.2919
Loa Loa (eye worm) beta-lactamase 0.0116 0.0372 0.048
Plasmodium falciparum thioredoxin reductase 0.0088 0.0266 0.1012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0164 0.0553 1
Echinococcus multilocularis steroid dehydrogenase 0.0021 0.0012 0.0004
Echinococcus multilocularis 0.0147 0.0492 0.0485
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0048 0.0145
Brugia malayi hypothetical protein 0.1279 0.4787 0.626
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0684 0.2527 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0021 0.0012 0.0017
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0021 0.0013 0.0011
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0078 0.0227 0.0219
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0147 0.0492 0.1759
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.0372 0.1433
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0021 0.0013 0.0011
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0021 0.0013 0.0011
Trichomonas vaginalis penicillin-binding protein, putative 0.0116 0.0372 0.1433
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0048 0.0145
Brugia malayi follicle stimulating hormone receptor 0.0967 0.3603 0.4711
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0164 0.0556 0.1149
Treponema pallidum exodeoxyribonuclease (exoA) 0.0079 0.0231 0.1634
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0048 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.0553 0.2153
Brugia malayi hypothetical protein 0.0021 0.0012 0.0015
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0021 0.0013 0.0017
Echinococcus multilocularis aryl hydrocarbon receptor 0.0183 0.0626 0.0619
Loa Loa (eye worm) hypothetical protein 0.0087 0.0262 0.0336
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0164 0.0553 0.0717
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0021 0.0013 0.0035
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Loa Loa (eye worm) hypothetical protein 0.0164 0.0556 0.0721
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0021 0.0012 0.0032
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0021 0.0013 0.0005
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0147 0.0492 0.191
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Brugia malayi hypothetical protein 0.0019 0.0005 0.0007
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0021 0.0013 0.0005
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0021 0.0013 0.0011
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.001
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0021 0.0013 0.0005
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.023 0.0804 0.0797
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0079 0.0231 0.0295
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0147 0.0492 0.3003
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0164 0.0556 0.0721
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0008
Loa Loa (eye worm) oxidoreductase 0.0021 0.0012 0.0008
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0079 0.0231 0.0871
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0012 0.0004
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0223 0.0779 1
Trypanosoma brucei cytochrome P450, putative 0.023 0.0805 0.3155
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0021 0.0013 0.0005
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.0048 0.0145
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0021 0.0013 0.0005
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0147 0.0492 0.3003
Echinococcus granulosus nuclear receptor nhr 48 0.0078 0.0227 0.0459
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0164 0.0556 0.0721
Trypanosoma brucei hypothetical protein, conserved 0.0116 0.0372 0.1433
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0012 0.0009
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0121 0.039 0.0383
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0019 0.0005 0.0007
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.001
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.0013 0.0005
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Schistosoma mansoni RAR-like nuclear receptor 0.0164 0.0556 0.1529
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0164 0.0556 0.1149
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0078 0.0227 0.0219
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0087 0.0262 0.0533
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0147 0.0492 0.1759
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0021 0.0013 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0164 0.0556 0.0549
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0116 0.0372 0.048
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0078 0.0227 0.0459
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0048 0.0041
Echinococcus granulosus hypothetical protein 0.0021 0.0012 0.0009
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.0013 0.0005
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0021 0.0013 0.0005
Schistosoma mansoni aryl hydrocarbon receptor 0.0606 0.2232 0.6137
Loa Loa (eye worm) hypothetical protein 0.0164 0.0556 0.0721
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0021 0.0012 0.0017
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0146 0.0536
Loa Loa (eye worm) dehydrogenase 0.0021 0.0012 0.0008
Onchocerca volvulus 0.0261 0.0923 0.2525
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0201 0.0694 0.2498
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Toxoplasma gondii exonuclease III APE 0.0079 0.0231 0.0871
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0142 0.0472 0.0617
Echinococcus granulosus Nuclear hormone receptor HR96 0.0078 0.0227 0.0459
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0169 0.0575 0.2239
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Schistosoma mansoni hypothetical protein 0.0036 0.0067 0.0185
Echinococcus multilocularis survival motor neuron protein 1 0.1279 0.4787 0.4784
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0021 0.0013 0.0021
Schistosoma mansoni nuclear hormone receptor 0.0164 0.0556 0.1529
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0147 0.0492 0.1759
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0079 0.0231 0.0803
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0684 0.2527 0.6947
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0164 0.0556 0.0721
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0021 0.0013 0.0008
Schistosoma mansoni transcription factor LCR-F1 0.043 0.1565 0.4304
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0684 0.2527 0.6947
Brugia malayi Cytochrome P450 family protein 0.0147 0.0492 0.0643
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) oxidoreductase 0.0021 0.0012 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus granulosus thioredoxin glutathione reductase 0.0088 0.0268 0.0545
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.013 0.017
Echinococcus multilocularis retinol dehydrogenase 13 0.0021 0.0012 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.039 0.2365
Brugia malayi hypoxia-induced factor 1 0.185 0.6954 0.9093
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0012 0.0032
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0078 0.0227 0.029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.1167 0.4592
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0088 0.0268 0.0261
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0048 0.0145
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0021 0.0013 0.0008
Entamoeba histolytica hypothetical protein 0.043 0.1565 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0147 0.0492 0.191
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Entamoeba histolytica hypothetical protein 0.043 0.1565 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.0005
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0021 0.0013 0.001
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0021 0.0013 0.0035
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0021 0.0013 0.0035
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0013 0.0005
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Brugia malayi nuclear hormone receptor family member nhr-6 0.0078 0.0227 0.0296
Brugia malayi Dehydrogenases, short chain protein 2 0.0021 0.0012 0.0015
Onchocerca volvulus 0.0976 0.3637 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0078 0.0227 0.0609
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0021 0.0013 0.0011
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0021 0.0013 0.0035
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0164 0.0556 0.1517
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0147 0.0492 0.3003
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0164 0.0556 0.1529
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0121 0.039 0.08
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.023 0.0804 0.221
Mycobacterium tuberculosis Possible penicillin-binding protein 0.074 0.2742 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0078 0.0227 0.029
Trichomonas vaginalis ap endonuclease, putative 0.0079 0.0231 0.0871
Echinococcus granulosus oxidoreductase 0.0021 0.0012 0.0009
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0012 0.0032
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0164 0.0556 0.0549
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0021 0.0013 0.0011
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Plasmodium falciparum ubiquitin specific protease, putative 0.0021 0.0013 0.0005
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.023 0.0804 0.315
Mycobacterium ulcerans lipase LipD 0.0116 0.0372 0.2254
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0088 0.0266 0.0932
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0147 0.0492 0.1759
Loa Loa (eye worm) hypothetical protein 0.0164 0.0556 0.0721
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0147 0.0492 0.1759
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0164 0.0556 0.0727
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0021 0.0013 0.0035
Brugia malayi Cytochrome P450 family protein 0.023 0.0805 0.1053
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0169 0.0575 0.2239
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Conserved protein 0.0116 0.0372 0.132
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.043 0.1565 0.1559
Onchocerca volvulus 0.0442 0.1611 0.4422
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0013 0.0005
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0021 0.0013 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0967 0.3603 0.4707
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0164 0.0553 0.2153
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0147 0.0492 0.1759
Echinococcus granulosus dual specificity protein kinase clk2 0.0684 0.2527 0.5271
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0021 0.0013 0.0011
Trichomonas vaginalis ubiquitin specific protease, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0164 0.0556 0.0721
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0048 0.0227
Schistosoma mansoni hypothetical protein 0.0261 0.0923 0.2536
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.1167 0.4592
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0087 0.0262 0.0336
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi nuclear hormone receptor family member odr-7 0.0078 0.0227 0.0296
Trichomonas vaginalis guanylate cyclase, putative 0.0164 0.0553 0.2153
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Loa Loa (eye worm) oxidoreductase 0.0021 0.0012 0.0008
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0079 0.0231 0.0871
Loa Loa (eye worm) hypothetical protein 0.1279 0.4787 0.6257
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0021 0.0012 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0164 0.0556 0.0727
Echinococcus granulosus aryl hydrocarbon receptor 0.0183 0.0626 0.1295
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0064 0.0175 0.0467
Loa Loa (eye worm) hypothetical protein 0.0087 0.0262 0.0336
Loa Loa (eye worm) hypothetical protein 0.0164 0.0556 0.0721
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0012 0.0032
Onchocerca volvulus 0.0078 0.0227 0.0609
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0147 0.0492 0.3003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.1167 0.4592
Echinococcus granulosus FTZ F1 alpha 0.0164 0.0556 0.1149
Loa Loa (eye worm) cytochrome P450 family protein 0.0388 0.1406 0.1833
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.001
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0048 0.0145
Onchocerca volvulus 0.0021 0.0012 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0012 0.0004
Loa Loa (eye worm) hypothetical protein 0.0504 0.1844 0.2406
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0087 0.0262 0.072
Trichomonas vaginalis conserved hypothetical protein 0.023 0.0804 0.315
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Echinococcus granulosus hypothetical protein 0.0021 0.0012 0.0009
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0079 0.0231 0.0224
Onchocerca volvulus 0.0021 0.0012 0.0017
Mycobacterium tuberculosis Probable lipase LipD 0.0116 0.0372 0.132
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.1167 0.4592
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0079 0.0231 0.0871
Echinococcus granulosus intermediate filament protein 0.0976 0.3637 0.7594
Trichomonas vaginalis ubiquitin specific protease, putative 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Plasmodium falciparum glutathione reductase 0.003 0.0048 0.0145
Loa Loa (eye worm) hypothetical protein 0.0453 0.1653 0.2155
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Echinococcus multilocularis FTZ F1 alpha 0.0164 0.0556 0.0549
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) oxidoreductase 0.0021 0.0012 0.0008
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.001
Mycobacterium leprae conserved hypothetical protein 0.0116 0.0372 0.4699
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0048 0.0145
Schistosoma mansoni lamin 0.0976 0.3637 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0147 0.0492 0.1759
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0146 0.0536
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0048 0.0145
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.0372 0.1433
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Schistosoma mansoni aldehyde dehydrogenase 0.0121 0.039 0.1072
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0008
Treponema pallidum fructose-bisphosphate aldolase 0.0325 0.1167 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.001
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Plasmodium falciparum glutathione reductase 0.0088 0.0266 0.1012
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0013 0.0005
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0684 0.2527 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.0372 0.048
Mycobacterium leprae Probable lipase LipE 0.0116 0.0372 0.4699
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0147 0.0492 0.1759
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Brugia malayi Steroid receptor seven-up type 2 0.0164 0.0556 0.0727
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0021 0.0013 0.0005
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0078 0.0227 0.0609
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0142 0.0472 0.0972
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0019 0.0005 0.0014
Echinococcus granulosus WW domain containing oxidoreductase 0.0021 0.0012 0.0009
Brugia malayi Cytochrome P450 family protein 0.023 0.0805 0.1053
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0184 0.063 0.172
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0164 0.0556 0.1149
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0146 0.0536
Brugia malayi hypothetical protein 0.0504 0.1844 0.2411
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0078 0.0227 0.0623
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0012 0.0032
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0164 0.0556 0.0549
Mycobacterium tuberculosis Probable esterase LipL 0.0116 0.0372 0.132
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0146 0.0536
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0325 0.1167 0.7433
Loa Loa (eye worm) oxidoreductase 0.0021 0.0012 0.0008
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0021 0.0013 0.0005
Echinococcus granulosus beta LACTamase domain containing family member 0.0116 0.0372 0.0763
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0078 0.0227 0.0459
Loa Loa (eye worm) oxidoreductase 0.0021 0.0012 0.0008
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0021 0.0013 0.0011
Echinococcus multilocularis musashi 0.0976 0.3637 0.3633
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Onchocerca volvulus Sepiapterin reductase homolog 0.0021 0.0012 0.0017
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0021 0.0012 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Plasmodium vivax thioredoxin reductase, putative 0.0088 0.0266 0.1012
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0048 0.0145
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0021 0.0012 0.0009
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0146 0.0185
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0021 0.0013 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0012 0.0015
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0087 0.0262 0.072
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0021 0.0012 0.0009
Echinococcus granulosus ubiquitin specific peptidase c family 0.0021 0.0013 0.0011
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Giardia lamblia Kinase, CMGC CLK 0.0684 0.2527 1
Loa Loa (eye worm) hypothetical protein 0.0471 0.172 0.2244
Mycobacterium tuberculosis Probable hydrolase 0.0116 0.0372 0.132
Plasmodium vivax hypothetical protein, conserved 0.0116 0.0372 0.1433
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0976 0.3637 0.4752
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0013 0.0008
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0012 0.0004
Schistosoma mansoni ap endonuclease 0.0079 0.0231 0.0634
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.013 0.017
Loa Loa (eye worm) thioredoxin reductase 0.0088 0.0266 0.0341
Schistosoma mansoni nuclear receptor 0.0078 0.0227 0.0623
Loa Loa (eye worm) hypothetical protein 0.0116 0.0372 0.048
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.1167 0.4592
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0164 0.0553 0.2153
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.029
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0021 0.0013 0.0005
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0013 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0146 0.0536
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Echinococcus granulosus hypothetical protein 0.0678 0.2505 0.5226
Echinococcus multilocularis transient receptor potential cation channel 0.0021 0.0012 0.0004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0021 0.0013 0.0005
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.023 0.0804 0.315
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0013 0.0017
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0021 0.0013 0.0005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.023 0.0804 0.1051
Brugia malayi orphan nuclear receptor NR2E1 0.0078 0.0227 0.0296
Schistosoma mansoni carbonyl reductase 0.0021 0.0012 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0021 0.0013 0.0005
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0079 0.0231 0.137
Onchocerca volvulus 0.01 0.0311 0.0841
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0471 0.172 0.1714
Loa Loa (eye worm) hypothetical protein 0.0116 0.0372 0.048
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0021 0.0012 0.0017

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 1.4 % In vitro inhibitory effect on D-Galactosamine induced cytotoxicity in primary cultured rat hepatocytes at 0.3 microg/mL ChEMBL. No reference
Inhibition (functional) = 1.4 % In vitro inhibitory effect on D-Galactosamine induced cytotoxicity in primary cultured rat hepatocytes at 3 microg/mL ChEMBL. No reference
Inhibition (functional) = 1.5 % In vitro inhibitory effect on D-Galactosamine induced cytotoxicity in primary cultured rat hepatocytes at 1 microg/mL ChEMBL. No reference
Inhibition (functional) = 3.8 % In vitro inhibitory effect on D-Galactosamine induced cytotoxicity in primary cultured rat hepatocytes at 10 microg/mL ChEMBL. No reference
Inhibition (functional) = 4.5 % In vitro inhibitory effect on D-Galactosamine induced cytotoxicity in primary cultured rat hepatocytes at 30 microg/mL ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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