Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0236 | 0.0236 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | AKH receptor | 0.0066 | 0.0389 | 0.0374 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0389 | 0.0374 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0158 | 0.084 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | opsin-like receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.0828 | 0.0828 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0035 | 0.0074 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | g protein coupled receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0143 | 0.0128 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0236 | 0.0236 |
Schistosoma mansoni | amine GPCR | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0158 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0042 | 0.0042 |
Echinococcus granulosus | acetylcholinesterase | 0.129 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.129 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0035 | 0.0074 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0164 | 0.0164 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Plasmodium vivax | glutathione reductase, putative | 0.0061 | 0.0347 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0061 | 0.0347 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | neuropeptide F receptor | 0.0066 | 0.0389 | 0.0374 |
Schistosoma mansoni | adenoreceptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0021 | 0.0035 | 0.0125 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0158 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0143 | 0.0143 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0021 | 0.0035 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0158 | 0.0158 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0328 | 0.0328 |
Brugia malayi | GnHR receptor homolog | 0.0066 | 0.0389 | 0.0374 |
Brugia malayi | Carboxylesterase family protein | 0.0218 | 0.1581 | 0.1568 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0066 | 0.0389 | 0.1623 |
Schistosoma mansoni | biogenic amine receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.0828 | 0.0814 |
Schistosoma mansoni | amine GPCR | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | sex peptide receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0158 | 0.084 |
Echinococcus multilocularis | g protein coupled receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0158 | 0.0158 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0021 | 0.0035 | 0.0074 |
Echinococcus multilocularis | g protein coupled receptor | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0158 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0145 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.1297 | 0.1297 |
Brugia malayi | Carboxylesterase family protein | 0.0218 | 0.1581 | 0.1568 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0021 | 0.0035 | 0.0074 |
Brugia malayi | G-protein coupled receptor | 0.0066 | 0.0389 | 0.0374 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0021 | 0.0035 | 0.0125 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0158 | 0.0158 |
Brugia malayi | ORL1-like opioid receptor | 0.0066 | 0.0389 | 0.0374 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0218 | 0.1581 | 0.1581 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0218 | 0.1581 | 0.92 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0158 | 0.0158 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0035 | 0.0074 |
Brugia malayi | RE15519p | 0.0066 | 0.0389 | 0.0374 |
Loa Loa (eye worm) | carboxylesterase | 0.0218 | 0.1581 | 0.1581 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0019 | 0.0019 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Schistosoma mansoni | neuropeptide receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0019 | 0.0019 |
Schistosoma mansoni | neuropeptide receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | opsin-like receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Brugia malayi | beta-lactamase | 0.0037 | 0.0158 | 0.0143 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0218 | 0.1581 | 0.92 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0235 | 0.1717 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0218 | 0.1581 | 0.1581 |
Plasmodium falciparum | thioredoxin reductase | 0.0021 | 0.0035 | 0.0588 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0021 | 0.0035 | 0.0074 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0389 | 0.0374 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0236 | 0.0236 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0021 | 0.0035 | 0.0074 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0158 | 0.0913 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0218 | 0.1581 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0021 | 0.0035 | 0.0588 |
Echinococcus granulosus | neuropeptide receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0218 | 0.1581 | 0.1581 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0389 | 0.0374 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0066 | 0.0389 | 0.0374 |
Brugia malayi | Dopamine receptor | 0.0066 | 0.0389 | 0.0374 |
Echinococcus multilocularis | fmrfamide receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0066 | 0.0389 | 0.0374 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0389 | 0.0374 |
Schistosoma mansoni | gliotactin | 0.0218 | 0.1581 | 0.1581 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0158 | 0.0143 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0158 | 0.0913 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0236 | 0.0236 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0021 | 0.0035 | 0.0115 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0066 | 0.0389 | 0.0374 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0015 | 0.0015 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0005 | 0.0005 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0066 | 0.0389 | 0.1623 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0158 | 0.0913 |
Schistosoma mansoni | opsin-like receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0061 | 0.0347 | 0.0347 |
Schistosoma mansoni | amine GPCR | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0143 | 0.0143 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0413 | 0.0413 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0021 | 0.0035 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.129 | 1 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0021 | 0.0035 | 0.0125 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0021 | 0.0035 | 0.0588 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0015 | 0.0015 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0218 | 0.1581 | 0.1581 |
Schistosoma mansoni | biogenic amine receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.1581 | 0.1581 |
Brugia malayi | Serotonin receptor | 0.0066 | 0.0389 | 0.0374 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0328 | 0.0328 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | fmrfamide receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | sex peptide receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0389 | 0.0374 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.1581 | 0.1581 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0021 | 0.0035 | 0.0115 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0158 | 0.0158 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0389 | 0.0374 |
Echinococcus multilocularis | neuroligin | 0.0218 | 0.1581 | 0.1581 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0182 | 0.0182 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Toxoplasma gondii | thioredoxin reductase | 0.0061 | 0.0347 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | Dopamine receptor protein 1 | 0.0066 | 0.0389 | 0.0374 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0158 | 0.054 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0158 | 0.0913 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.0828 | 0.0828 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0158 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0218 | 0.1581 | 1 | |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0218 | 0.1581 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.0163 | 0.0149 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0269 | 0.0255 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0158 | 0.084 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0066 | 0.0389 | 0.0374 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0218 | 0.1581 | 0.1581 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0158 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.1581 | 0.1581 |
Onchocerca volvulus | 0.0218 | 0.1581 | 1 | |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0061 | 0.0347 | 0.1254 |
Brugia malayi | G protein-coupled receptor | 0.0066 | 0.0389 | 0.0374 |
Echinococcus multilocularis | neuropeptide receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | allatostatin A receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | Carboxylesterase family protein | 0.0218 | 0.1581 | 0.1568 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0035 | 0.0074 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0158 | 0.0143 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0356 | 0.2663 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0158 | 0.084 |
Echinococcus multilocularis | fmrfamide receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0389 | 0.0374 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0021 | 0.0035 | 0.0035 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0218 | 0.1581 | 0.1581 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0158 | 0.0158 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0019 | 0.0019 |
Schistosoma mansoni | neuropeptide receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | orexin receptor type 2 | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0158 | 0.0158 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0158 | 0.0913 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0021 | 0.0035 | 0.0074 |
Echinococcus multilocularis | acetylcholinesterase | 0.129 | 1 | 1 |
Brugia malayi | larval opioid receptor | 0.0066 | 0.0389 | 0.0374 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0066 | 0.0389 | 0.0389 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0158 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | amine GPCR | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0218 | 0.1581 | 0.1581 |
Brugia malayi | Thioredoxin reductase | 0.0061 | 0.0347 | 0.0333 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0158 | 0.054 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0145 | 0.0145 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0158 | 0.084 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.129 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Trypanosoma brucei | trypanothione reductase | 0.0061 | 0.0347 | 0.1254 |
Echinococcus granulosus | acetylcholinesterase | 0.129 | 1 | 1 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0236 | 0.0236 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0158 | 0.0913 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0158 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0218 | 0.1581 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0218 | 0.1581 | 0.1581 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0158 | 0.0158 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0021 | 0.0035 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0158 | 0.084 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0021 | 0.0035 | 0.0588 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0158 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0197 | 0.0197 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0035 | 0.0074 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0158 | 0.084 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | carboxylesterase | 0.0218 | 0.1581 | 0.1581 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0218 | 0.1581 | 0.1581 |
Echinococcus granulosus | neuropeptide s receptor | 0.0066 | 0.0389 | 0.0389 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0158 | 0.054 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0061 | 0.0347 | 0.1952 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0269 | 0.0269 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0356 | 0.2663 | 0.2652 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0021 | 0.0035 | 0.0125 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0158 | 0.4304 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0021 | 0.0035 | 0.0074 |
Echinococcus granulosus | carboxylesterase 5A | 0.129 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0066 | 0.0389 | 0.0374 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0356 | 0.2663 | 1 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | carboxylesterase | 0.129 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0218 | 0.1581 | 0.1568 |
Echinococcus granulosus | serotonin receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0158 | 0.0143 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.129 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0389 | 0.0374 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0021 | 0.0035 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0236 | 0.0236 |
Echinococcus multilocularis | carboxylesterase 5A | 0.129 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0269 | 0.0255 |
Echinococcus granulosus | neuroligin | 0.0218 | 0.1581 | 0.1581 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0066 | 0.0389 | 0.0389 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0021 | 0.0035 | 0.0588 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0218 | 0.1581 | 0.1581 |
Brugia malayi | glutathione reductase | 0.0061 | 0.0347 | 0.0333 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0021 | 0.0035 | 0.0115 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0021 | 0.0035 | 0.0035 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0021 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | neuropeptide receptor | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.1581 | 0.1581 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | Serotonin receptor | 0.0512 | 0.3889 | 0.3879 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0158 | 0.0158 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0021 | 0.0035 | 0.0588 |
Brugia malayi | follicle stimulating hormone receptor | 0.0066 | 0.0389 | 0.0374 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0236 | 0.0222 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | putative neuropeptide receptor | 0.0066 | 0.0389 | 0.0374 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.1581 | 0.1581 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0218 | 0.1581 | 0.92 |
Brugia malayi | Melatonin receptor type 1A | 0.0066 | 0.0389 | 0.0374 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | somatostatin receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | g protein coupled receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | Bromodomain containing protein | 0.0073 | 0.0446 | 0.0431 |
Brugia malayi | Dopamine receptor protein 2 | 0.0066 | 0.0389 | 0.0374 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0066 | 0.0389 | 0.0389 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0061 | 0.0347 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0218 | 0.1581 | 0.1581 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0158 | 0.0158 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0236 | 0.0236 |
Echinococcus multilocularis | serotonin receptor | 0.0066 | 0.0389 | 0.0389 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0021 | 0.0035 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0061 | 0.0347 | 0.0347 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0028 | 0.0028 |
Echinococcus granulosus | somatostatin receptor | 0.0066 | 0.0389 | 0.0389 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0021 | 0.0035 | 0.0588 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | neuropeptide receptor | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0218 | 0.1581 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | myosin xvIII | 0.0066 | 0.0389 | 0.0389 |
Echinococcus multilocularis | allatostatin A receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | G-protein coupled receptor | 0.0066 | 0.0389 | 0.0374 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.006 | 0.0045 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0066 | 0.0389 | 0.0374 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0021 | 0.0035 | 0.0125 |
Brugia malayi | hypothetical protein | 0.0218 | 0.1581 | 0.1568 |
Treponema pallidum | NADH oxidase | 0.0021 | 0.0035 | 1 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0066 | 0.0389 | 0.0374 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Loa Loa (eye worm) | hypothetical protein | 0.129 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0015 | 0.0015 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Echinococcus granulosus | neuropeptides capa receptor | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0218 | 0.1581 | 1 | |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Brugia malayi | sulfakinin receptor protein | 0.0066 | 0.0389 | 0.0374 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0066 | 0.0389 | 0.0389 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0158 | 0.054 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0066 | 0.0389 | 0.0374 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | g-protein coupled receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | g protein coupled receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0269 | 0.0269 |
Loa Loa (eye worm) | hypothetical protein | 0.0356 | 0.2663 | 0.2663 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0028 | 0.0028 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0066 | 0.0389 | 0.0389 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0356 | 0.2663 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0066 | 0.0389 | 0.0389 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0021 | 0.0035 | 0.0588 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0158 | 0.0913 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0158 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | amine GPCR | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0158 | 0.084 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0389 | 0.0374 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0015 | 0.0015 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0158 | 0.4304 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.1581 | 0.1581 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0066 | 0.0389 | 0.0389 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0035 | 0.0074 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0158 | 0.084 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0158 | 0.0158 |
Echinococcus granulosus | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0158 | 0.084 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0035 | 0.0074 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0021 | 0.0035 | 0.002 |
Leishmania major | trypanothione reductase | 0.0061 | 0.0347 | 0.1254 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0021 | 0.0035 | 0.0074 |
Echinococcus multilocularis | acetylcholinesterase | 0.129 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0218 | 0.1581 | 1 | |
Echinococcus multilocularis | serotonin receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | histamine h1 receptor | 0.0066 | 0.0389 | 0.0389 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.0356 | 0.0356 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.1581 | 0.1581 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0021 | 0.0035 | 0.0074 |
Brugia malayi | neuropeptide F receptor | 0.0066 | 0.0389 | 0.0374 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0158 | 0.0158 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0021 | 0.0035 | 0.0115 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0061 | 0.0347 | 0.0347 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0158 | 0.0913 |
Plasmodium falciparum | glutathione reductase | 0.0061 | 0.0347 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0061 | 0.0347 | 0.0347 |
Schistosoma mansoni | acetylcholinesterase | 0.0218 | 0.1581 | 0.1581 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0042 | 0.0042 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0158 | 0.0913 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.0389 | 0.0389 |
Schistosoma mansoni | biogenic amine receptor | 0.0066 | 0.0389 | 0.0389 |
Onchocerca volvulus | 0.0066 | 0.0389 | 0.1623 | |
Brugia malayi | hypothetical protein | 0.0066 | 0.0389 | 0.0374 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0066 | 0.0389 | 0.0389 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0035 | 0.0074 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0042 | 0.0042 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | = 0.4 uM | Cytotoxicity against human MCF7 cells | ChEMBL. | 20356752 |
GI50 (functional) | = 1.7 uM | Cytotoxicity against human NCI-H460 cells | ChEMBL. | 20356752 |
GI50 (functional) | = 1.9 uM | Cytotoxicity against human K562 cells | ChEMBL. | 20356752 |
GI50 (ADMET) | = 2.2 uM | Cytotoxicity against BALB mouse 3T3 cells | ChEMBL. | 20356752 |
GI50 (functional) | = 2.5 uM | Cytotoxicity against human M14 cells | ChEMBL. | 20356752 |
GI50 (functional) | = 3.8 uM | Cytotoxicity against human HT-29 cells | ChEMBL. | 20356752 |
GI50 (functional) | = 4.6 uM | Cytotoxicity against human DU145 cells | ChEMBL. | 20356752 |
IC50 (functional) | = 22.9 uM | Antitrypanosomal activity against Trypanosoma cruzi tulahuen C4 trypomastigotes infected in african green monkey Vero cells assessed as CPRG cleavage after 120 hrs by microplate reader | ChEMBL. | 20356752 |
MIC (functional) | = 20.8 uM | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 7 days by microplate alamar blue assay | ChEMBL. | 20356752 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.