Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.1847 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.7052 | 0.6385 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.1847 | 0.5 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.1847 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.7052 | 0.6385 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.7052 | 0.6385 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.1847 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.1847 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.1847 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.1847 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.1847 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 1 |
Brugia malayi | hypothetical protein | 0.0037 | 0.7052 | 0.6385 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.1847 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.1847 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.1847 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.7052 | 0.6385 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.7052 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.7052 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.1847 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.7052 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.1847 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.1847 | 0.5 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.1847 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.7052 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.1847 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.