Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.3936 | 0.3936 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0072 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.1937 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.1937 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.9664 | 0.9664 |
Brugia malayi | hypothetical protein | 0.0029 | 0.1937 | 0.1937 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.7327 | 0.7327 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.9664 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.7327 | 0.7327 |
Echinococcus multilocularis | tar DNA binding protein | 0.0072 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0049 | 0.0049 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.9664 | 0.9664 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0072 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.1937 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.007 | 0.9664 | 0.9664 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.007 | 0.9664 | 0.9664 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.9664 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.1937 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 1 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.007 | 0.9664 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0072 | 1 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.1937 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.7327 | 0.7327 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.7327 | 0.7327 |
Echinococcus granulosus | tar DNA binding protein | 0.0072 | 1 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.007 | 0.9664 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.3936 | 0.3936 |
Brugia malayi | TAR-binding protein | 0.0072 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.3936 | 0.3936 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.9664 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.1937 | 0.1937 |
Loa Loa (eye worm) | TAR-binding protein | 0.0072 | 1 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.1937 | 0.5 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.007 | 0.9664 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.