Detailed information for compound 1134308

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 413.493 | Formula: C20H23N5O3S
  • H donors: 3 H acceptors: 4 LogP: 2.48 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)NCc1n[nH]c(c1)c1sc(nc1N1CCC(CC1)O)c1ccccc1
  • InChi: 1S/C20H23N5O3S/c1-28-20(27)21-12-14-11-16(24-23-14)17-18(25-9-7-15(26)8-10-25)22-19(29-17)13-5-3-2-4-6-13/h2-6,11,15,26H,7-10,12H2,1H3,(H,21,27)(H,23,24)
  • InChiKey: GFUMDRBVYNGSBP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis neutral sphingomyelinase 0.0008 0.0004 0.0005
Echinococcus granulosus bloom syndrome protein 0.0027 0.0173 0.0277
Schistosoma mansoni hypothetical protein 0.0696 0.6227 0.6225
Plasmodium vivax JmjC domain containing protein 0.0011 0.0025 0.032
Schistosoma mansoni terminal deoxycytidyl transferase 0.0202 0.1755 0.1752
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0225 0.2899
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.001 0.0023 0.0084
Schistosoma mansoni cpg binding protein 0.0032 0.0221 0.0218
Echinococcus granulosus traf and tnf receptor associated protein 0.0008 0.0004 0.0006
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0004 0.0004
Mycobacterium ulcerans beta-lactamase 0.0038 0.0276 0.0254
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.001 0.0016 0.0025
Schistosoma mansoni aldehyde dehydrogenase 0.001 0.0023 0.0019
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0162 0.0158
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0022
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0276 0.0254
Trypanosoma brucei hypothetical protein, conserved 0.0063 0.0496 0.1804
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0024 0.0039
Plasmodium falciparum metacaspase-like protein 0.0026 0.0162 0.2295
Trypanosoma cruzi DNA damage repair protein, putative 0.0063 0.0496 0.1793
Entamoeba histolytica hypothetical protein 0.0108 0.0909 0.5182
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0023
Leishmania major DNA polymerase eta, putative 0.0173 0.1491 0.5417
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0004 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0162 0.0158
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0024 0.0024
Echinococcus multilocularis peregrin 0.004 0.0295 0.0398
Loa Loa (eye worm) hypothetical protein 0.0056 0.0436 0.0436
Echinococcus multilocularis zinc finger protein 0.001 0.0016 0.0021
Brugia malayi Calcitonin receptor-like protein seb-1 0.0146 0.1252 0.1252
Brugia malayi jmjC domain containing protein 0.0107 0.0896 0.0896
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0024
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0413 0.0409
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0024 0.0033
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.0598 0.0598
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0024 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0231 0.2016 0.7331
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0276 0.0372
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0011 0.0026 0.0095
Schistosoma mansoni aldehyde dehydrogenase 0.0187 0.1621 0.1617
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0162 0.0576
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0011 0.0025 0.0077
Loa Loa (eye worm) hypothetical protein 0.01 0.0833 0.0833
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0008 0.0004 0.0013
Trichomonas vaginalis glutaminase, putative 0.1114 1 1
Loa Loa (eye worm) MBCTL1 0.0061 0.0479 0.0479
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.1248 0.1245
Trichomonas vaginalis ran, putative 0.0021 0.0115 0.0112
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.003 0.003
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0182 0.1122
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0024 0.0092
Brugia malayi Cell death protein 3 precursor 0.0026 0.0162 0.0162
Echinococcus multilocularis PHD finger protein rhinoceros 0.0033 0.0225 0.0303
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.003 0.0184
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0162 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0009 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0229 0.0225
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0318 0.2805 0.2803
Onchocerca volvulus 0.0038 0.0276 0.1203
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0024 0.0024
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0187 0.1621 0.2185
Trypanosoma brucei DNA polymerase kappa, putative 0.0231 0.2016 0.7331
Trypanosoma brucei DNA polymerase kappa, putative 0.0209 0.182 0.6617
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0033 0.0225 0.0221
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.001 0.0023 0.0069
Schistosoma mansoni coup transcription factor 0.001 0.0024 0.0021
Schistosoma mansoni phd/f-box containing protein 0.0011 0.0025 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0024 0.0024
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0182 0.0661
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.001 0.0023 0.0023
Brugia malayi Bloom's syndrome protein homolog 0.0027 0.0173 0.0173
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.0413 0.0409
Brugia malayi beta-lactamase family protein 0.0038 0.0276 0.0276
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.001 0.0023 0.003
Brugia malayi jmjC domain containing protein 0.0011 0.0025 0.0025
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0004 0.0021
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.001 0.0023 0.0069
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0191 0.2737
Plasmodium vivax exodeoxyribonuclease III, putative 0.0008 0.0004 0.0047
Schistosoma mansoni protein phosphatase 2C 0.0011 0.0025 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0276 0.099
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0009 0.0014
Entamoeba histolytica deoxycytidyl transferase, putative 0.0202 0.1755 1
Trypanosoma brucei Metacaspase-4 0.0026 0.0162 0.0588
Trichomonas vaginalis dullard protein, putative 0.0038 0.027 0.0266
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0011 0.0025 0.0153
Trypanosoma brucei DNA polymerase eta, putative 0.0312 0.275 1
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.001 0.0023 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0108 0.0909 0.0906
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0063 0.0496 0.3062
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0024
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0134 0.0475
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0038 0.027 0.1537
Toxoplasma gondii PHD-finger domain-containing protein 0.0011 0.0026 0.0161
Brugia malayi ImpB/MucB/SamB family protein 0.0202 0.1755 0.1755
Trypanosoma brucei DNA polymerase kappa, putative 0.0146 0.1253 0.4557
Echinococcus multilocularis 0.0038 0.027 0.0364
Loa Loa (eye worm) hypothetical protein 0.0011 0.003 0.003
Echinococcus granulosus caspase 0.0026 0.0162 0.026
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0008 0.0004 0.0013
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0225 0.1387
Brugia malayi Latrophilin receptor protein 2 0.0046 0.0348 0.0348
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0219 0.1907 0.3063
Echinococcus granulosus lysine specific demethylase 6a 0.0011 0.0025 0.004
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0061 0.0479 0.0647
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0024
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.001 0.0023 0.0036
Leishmania major hypothetical protein, conserved 0.0011 0.0025 0.0077
Brugia malayi hypothetical protein 0.0108 0.0909 0.0909
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0004 0.0052
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0094 0.0775 0.4784
Plasmodium vivax DNA repair protein REV1, putative 0.0063 0.0496 0.64
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0276 0.0272
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0008 0.0004 0.0021
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0059 0.0056
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.001 0.0023 0.003
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0115 0.0614
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0004 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0231 0.2016 0.7328
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.0598 0.096
Brugia malayi mbt repeat family protein 0.0053 0.0413 0.0413
Leishmania major aldehyde dehydrogenase, putative 0.001 0.0023 0.0069
Trichomonas vaginalis dullard protein, putative 0.0038 0.027 0.0266
Trypanosoma brucei DNA polymerase IV, putative 0.0231 0.2016 0.7331
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.027 0.0969
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0059 0.0339
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0229 0.0309
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0108 0.0909 0.1461
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.001 0.0023 0.0129
Plasmodium falciparum JmjC domain-containing protein, putative 0.0011 0.0025 0.0352
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0021
Echinococcus multilocularis cpg binding protein 0.0032 0.0221 0.0298
Loa Loa (eye worm) hypothetical protein 0.0038 0.0276 0.0276
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0038 0.027 0.027
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0004 0.0052
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.001 0.0023 0.0069
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0038 0.027 0.0433
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0004 0.0047
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0173 0.1491 0.9203
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0024 0.0024
Plasmodium falciparum importin beta, putative 0.0028 0.0182 0.2579
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0316 0.0508
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0024 0.0024
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.001 0.0023 0.0023
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0046 0.0348 0.0469
Loa Loa (eye worm) hypothetical protein 0.0038 0.0276 0.0276
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.003 0.0184
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.001 0.0023 0.0089
Brugia malayi PHD-finger family protein 0.0033 0.0225 0.0225
Schistosoma mansoni nuclear hormone receptor 0.001 0.0024 0.0021
Toxoplasma gondii exonuclease III APE 0.0041 0.0297 0.183
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0297 0.1066
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0026 0.0041
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0022
Treponema pallidum gamma-glutamyl phosphate reductase 0.001 0.0023 0.0276
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0094 0.0775 1
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0026 0.0162 0.0162
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0061 0.0479 0.077
Loa Loa (eye worm) acetyltransferase 0.0318 0.2805 0.2805
Echinococcus multilocularis phd:f box containing protein 0.0011 0.0025 0.0033
Echinococcus granulosus dnaJ subfamily B 0.0435 0.386 0.62
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0162 0.0158
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0038 0.027 0.0266
Trypanosoma brucei unspecified product 0.0139 0.1188 0.4321
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0162
Onchocerca volvulus 0.001 0.0024 0.0092
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.0041 0.0055
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0024 0.0021
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0202 0.1755 0.1755
Brugia malayi Probable ClpP-like protease 0.0084 0.069 0.069
Schistosoma mansoni hypothetical protein 0.0046 0.0348 0.0344
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0024 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0231 0.2016 0.7331
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0024 0.0092
Echinococcus granulosus importin subunit beta 1 0.0028 0.0182 0.0292
Brugia malayi acetyltransferase, GNAT family protein 0.0318 0.2805 0.2805
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0084 0.069 0.8898
Loa Loa (eye worm) hypothetical protein 0.0008 0.0004 0.0004
Schistosoma mansoni thyroid hormone receptor 0.001 0.0024 0.0021
Echinococcus granulosus caspase 2 0.0026 0.0162 0.026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0162
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0024 0.0024
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0046 0.0348 0.0469
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0038 0.027 0.0266
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.1248 0.1245
Echinococcus multilocularis peptidase Clp (S14 family) 0.0055 0.0428 0.0577
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0008 0.0004 0.0021
Schistosoma mansoni zinc finger protein 0.001 0.0016 0.0012
Schistosoma mansoni ap endonuclease 0.0041 0.0297 0.0293
Schistosoma mansoni aldehyde dehydrogenase 0.0187 0.1621 0.1617
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0021
Mycobacterium ulcerans DNA polymerase IV 0.0231 0.2016 0.1998
Loa Loa (eye worm) PHD-finger family protein 0.0033 0.0225 0.0225
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0209 0.182 0.8501
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.1248 0.1684
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0041 0.0297 0.4106
Trypanosoma brucei metacaspase MCA2 0.0026 0.0162 0.0588
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0297 0.04
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.001 0.0023 0.003
Brugia malayi jmjC domain containing protein 0.0011 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.01 0.0833 0.083
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.001 0.0023 0.0036
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.001 0.0023 0.0082
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0038 0.027 0.1664
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0229 0.0225
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0276 0.0272
Plasmodium vivax importin-beta 2, putative 0.0028 0.0182 0.2345
Trichomonas vaginalis esterase, putative 0.0038 0.0276 0.0272
Loa Loa (eye worm) hypothetical protein 0.0012 0.0042 0.0042
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0276 0.0276
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0209 0.182 0.6612
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0187 0.1621 0.2603
Echinococcus granulosus JmjC domain containing protein 4 0.0011 0.0025 0.004
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0229 0.1413
Brugia malayi aldehyde dehydrogenase 0.001 0.0023 0.0023
Trypanosoma cruzi DNA polymerase eta, putative 0.0173 0.1491 0.5417
Brugia malayi polk-prov protein 0.0092 0.0757 0.0757
Giardia lamblia DNA damage repair protein 0.0063 0.0496 0.2712
Brugia malayi PHD-finger family protein 0.001 0.0016 0.0016
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0025 0.0025
Trichomonas vaginalis DNA helicase recq1, putative 0.0027 0.0173 0.0169
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0053 0.0413 0.1809
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0021
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0038 0.027 0.0266
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0146 0.1252 0.1252
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0059 0.0203
Echinococcus granulosus histone acetyltransferase MYST2 0.0061 0.0479 0.077
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0024 0.0024
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0084 0.069 0.5
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0276 0.0272
Trypanosoma cruzi DNA polymerase kappa, putative 0.0231 0.2016 0.7328
Loa Loa (eye worm) hypothetical protein 0.0092 0.0757 0.0757
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0024 0.0024
Echinococcus multilocularis traf and tnf receptor associated protein 0.0008 0.0004 0.0005
Brugia malayi Aldehyde dehydrogenase protein 4 0.001 0.0023 0.0023
Brugia malayi jmjC domain containing protein 0.0041 0.0303 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus geminin 0.0696 0.6227 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0061 0.0479 0.0647
Trichomonas vaginalis DNA helicase recq, putative 0.0027 0.0173 0.0169
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.1248 0.1684
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0162 0.0158
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0297 0.1613
Onchocerca volvulus Alhambra homolog 0.0033 0.0225 0.0978
Schistosoma mansoni blooms syndrome DNA helicase 0.0021 0.0121 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0024 0.0024
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0024 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0097 0.0807 0.4597
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0146 0.1248 0.1248
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0318 0.2805 0.3783
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0162 0.0998
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0055 0.0428 0.1986
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.001 0.0023 0.0069
Schistosoma mansoni myelin transcription factor 1 myt1 0.0061 0.0479 0.0476
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0162 0.2086
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0297 0.4207
Trypanosoma brucei DNA polymerase kappa, putative 0.0231 0.2016 0.7331
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0108 0.0909 0.1226
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.001 0.0023 0.0069
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0276 0.3555
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0024 0.0024
Schistosoma mansoni bromodomain containing protein 0.001 0.0016 0.0012
Echinococcus multilocularis dna polymerase eta 0.0312 0.275 0.3709
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0061 0.0479 0.0479
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0024 0.0033
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0206 0.0206
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0202 0.1755 0.2819
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0011 0.0025 0.009
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.007 0.0561 0.3462
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0011 0.003 0.004
Mycobacterium tuberculosis Conserved protein 0.0038 0.0276 0.1273
Mycobacterium ulcerans aldehyde dehydrogenase 0.0187 0.1621 0.1602
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.001 0.0023 0.0139
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0024 0.0033
Schistosoma mansoni jumonji domain containing protein 0.0085 0.0698 0.0694
Loa Loa (eye worm) hypothetical protein 0.0008 0.0004 0.0004
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.001 0.0023 0.0019
Entamoeba histolytica hypothetical protein 0.0108 0.0909 0.5182
Echinococcus multilocularis JmjC domain containing protein 4 0.0011 0.0025 0.0033
Leishmania major importin beta-1 subunit, putative 0.0023 0.0134 0.0475
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0244 0.214 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0598 0.2164
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.0413 0.0556
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0297 0.0297
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0115 0.1634
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0115 0.0711
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0297 0.1371
Brugia malayi CXXC zinc finger family protein 0.0031 0.0206 0.0206
Echinococcus granulosus histone acetyltransferase KAT2B 0.0309 0.2725 0.4376
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.0598 0.0806
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0024 0.0039
Entamoeba histolytica protein kinase, putative 0.0097 0.0807 0.4597
Onchocerca volvulus 0.0031 0.0206 0.0893
Mycobacterium tuberculosis Conserved hypothetical protein 0.0202 0.1755 0.8198
Echinococcus granulosus PHD finger protein rhinoceros 0.0033 0.0225 0.0361
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0024 0.0033
Onchocerca volvulus Huntingtin homolog 0.0132 0.112 0.4938
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0162 0.0158
Echinococcus multilocularis GPCR, family 2 0.0046 0.0348 0.0469
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0024 0.0021
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0276 0.1002
Schistosoma mansoni hypothetical protein 0.0298 0.2622 0.262
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0115 0.0115
Trypanosoma brucei metacaspase MCA3 0.0026 0.0162 0.0588
Schistosoma mansoni transcription factor LCR-F1 0.0108 0.0909 0.0906
Schistosoma mansoni aldehyde dehydrogenase 0.001 0.0023 0.0019
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0132 0.112 0.112
Brugia malayi nuclear hormone receptor 0.001 0.0024 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0276 0.0272
Brugia malayi Importin beta-1 subunit 0.0028 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0038 0.0276 0.0276
Schistosoma mansoni hypothetical protein 0.0046 0.0348 0.0344
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0026 0.0035
Entamoeba histolytica hypothetical protein 0.0108 0.0909 0.5182
Trypanosoma brucei hypothetical protein, conserved 0.0063 0.0496 0.1804
Mycobacterium ulcerans glutaminase 0.1114 1 1
Mycobacterium leprae Probable lipase LipE 0.0038 0.0276 0.3791
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0046 0.0348 0.0559
Loa Loa (eye worm) hypothetical protein 0.0008 0.0004 0.0004
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.001 0.0023 0.0082
Schistosoma mansoni hypothetical protein 0.001 0.0023 0.0019
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0276 0.0254
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0038 0.027 0.348
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0534 0.3293
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0008 0.0004 0.0021
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0276 0.1273
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.034 0.0459
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0024 0.0021
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0097 0.0807 0.2933
Trypanosoma cruzi hypothetical protein, conserved 0.0063 0.0496 0.1793
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0333 0.294 0.2937
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0231 0.2016 0.2014
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0828 0.7415 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0202 0.1755 0.2367
Trypanosoma brucei DNA damage repair protein, putative 0.0063 0.0496 0.1804
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0004 0.0004
Echinococcus granulosus neutral sphingomyelinase 0.0008 0.0004 0.0006
Schistosoma mansoni ran 0.0021 0.0115 0.0112
Loa Loa (eye worm) hypothetical protein 0.0312 0.275 0.275
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0059 0.0203
Loa Loa (eye worm) hypothetical protein 0.0084 0.069 0.069
Echinococcus multilocularis dnaJ subfamily B 0.0435 0.386 0.5206
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.001 0.0023 0.0069
Schistosoma mansoni caspase-3 (C14 family) 0.0026 0.0162 0.0158
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0084 0.069 0.0669
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.001 0.0007
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0187 0.1621 0.5887
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0024 0.0021
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0026 0.0162 0.026
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0084 0.069 0.0669
Echinococcus multilocularis deoxyribonuclease 1 2 0.0008 0.0004 0.0005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0024 0.0039
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0146 0.1252 0.1252
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0021
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.001 0.0023 0.0139
Leishmania major metacaspase, putative 0.0026 0.0162 0.0576
Giardia lamblia DINP protein human, muc B family 0.0209 0.182 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0187 0.1621 0.1602
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0303 0.0299
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0187 0.1621 0.7568
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0023
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0097 0.0807 0.2924
Onchocerca volvulus 0.0053 0.0413 0.1809
Trypanosoma cruzi metacaspase, putative 0.0026 0.0162 0.0576
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0011 0.003 0.004
Loa Loa (eye worm) aldehyde dehydrogenase 0.001 0.0023 0.0023
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0146 0.1252 0.1252
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0024
Schistosoma mansoni importin beta-1 0.0028 0.0182 0.0178
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0105 0.0102
Loa Loa (eye worm) hypothetical protein 0.0038 0.0276 0.0276
Brugia malayi RNA, U transporter 1 0.0079 0.0647 0.0647
Loa Loa (eye worm) glutaminase 0.1114 1 1
Schistosoma mansoni ran 0.0021 0.0115 0.0112
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0008 0.0004 0.0005
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0084 0.069 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0115 0.0419
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0182 0.0661
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0276 0.1273
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.0598 0.3407
Giardia lamblia Sgs1 DNA helicase, putative 0.0011 0.003 0.0145
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0297 0.169
Schistosoma mansoni ap endonuclease 0.0041 0.0297 0.0293
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0024 0.0021
Trichomonas vaginalis DNA polymerase eta, putative 0.0231 0.2016 0.2014
Echinococcus multilocularis dna polymerase kappa 0.0231 0.2016 0.2719
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.0413 0.0556
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0229 0.0368
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.1248 0.1245
Toxoplasma gondii aldehyde dehydrogenase 0.0187 0.1621 1
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0413 0.0409
Schistosoma mansoni hypothetical protein 0.0046 0.0348 0.0344
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0004 0.0004
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0598 0.2174
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0038 0.027 0.0266
Trypanosoma brucei metacaspase 5, putative 0.0026 0.0162 0.0588
Trichomonas vaginalis bromodomain-containing protein, putative 0.0094 0.0775 0.0772
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0022
Giardia lamblia Histone acetyltransferase GCN5 0.0086 0.0705 0.386
Entamoeba histolytica acetyltransferase, GNAT family 0.0086 0.0705 0.4016
Loa Loa (eye worm) hypothetical protein 0.0038 0.027 0.027
Echinococcus granulosus zinc finger protein 0.001 0.0016 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.1248 0.2005
Onchocerca volvulus 0.0038 0.0276 0.1203
Echinococcus multilocularis geminin 0.0696 0.6227 0.8397
Echinococcus granulosus phd:f box containing protein 0.0011 0.0025 0.004
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0276 0.0443
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0004 0.0006
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0134 0.013
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0011 0.003 0.003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0297 0.1066
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0162 0.0158
Giardia lamblia PHD finger protein 15 0.0033 0.0225 0.1218
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.001 0.0023 0.0089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0024 0.0024
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0225 0.1387
Brugia malayi CCR4 0.0008 0.0004 0.0004
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0276 0.3791
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.1248 0.2005
Brugia malayi Bromodomain containing protein 0.001 0.0016 0.0016
Entamoeba histolytica protein kinase, putative 0.0097 0.0807 0.4597
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0115 0.0155
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0011 0.0026 0.0161
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0011 0.003 0.0048
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0227 0.1981 0.1981
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0162 0.0158
Trypanosoma brucei metacaspase 0.0026 0.0162 0.0588
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.001 0.0023 0.0069
Trypanosoma brucei unspecified product 0.0224 0.1952 0.7096
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.0413 0.0663
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0024 0.0033
Loa Loa (eye worm) hypothetical protein 0.0033 0.0229 0.0229
Entamoeba histolytica hypothetical protein 0.0023 0.0134 0.0764
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0004 0.0004
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0004 0.0013
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0046 0.0348 0.0559
Leishmania major hypothetical protein, conserved 0.0038 0.0276 0.099
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0011 0.003 0.0048
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0526 0.0522
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.001 0.0023 0.0019
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0094 0.0775 0.0772
Trypanosoma brucei chrX additional, unordered contigs 0.0063 0.0496 0.1804
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0115 0.1486
Echinococcus multilocularis bloom syndrome protein 0.0027 0.0173 0.0233
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0297 0.1078
Echinococcus granulosus lysine specific demethylase 5A 0.0041 0.0303 0.0486
Plasmodium falciparum histone acetyltransferase GCN5 0.0086 0.0705 1
Loa Loa (eye worm) beta-lactamase 0.0038 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0061 0.0479 0.0479
Toxoplasma gondii ABC1 family protein 0.0038 0.0276 0.17
Echinococcus granulosus cpg binding protein 0.0032 0.0221 0.0355
Echinococcus granulosus dna polymerase eta 0.0312 0.275 0.4417
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0013 0.0043 0.0608
Schistosoma mansoni hypothetical protein 0.0046 0.0348 0.0344
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0024 0.0024
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0038 0.027 0.0364
Trypanosoma brucei DNA polymerase IV, putative 0.0231 0.2016 0.7331
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.001 0.0023 0.0069
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0024 0.0143 0.2031
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.001 0.0023 0.0089
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0004 0.0013
Mycobacterium ulcerans hypothetical protein 0.0038 0.0276 0.0254
Loa Loa (eye worm) hypothetical protein 0.0135 0.1153 0.1153
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0115 0.0185
Echinococcus granulosus caspase 8 0.0026 0.0162 0.026
Trypanosoma brucei aldehyde dehydrogenase, putative 0.001 0.0023 0.0082
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.001 0.0023 0.0069
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0038 0.027 0.0266
Echinococcus granulosus betaine aldehyde dehydrogenase 0.001 0.0023 0.0036
Schistosoma mansoni hypothetical protein 0.0435 0.386 0.3858
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0097 0.0807 0.2924
Trypanosoma cruzi metacaspase, putative 0.0026 0.0162 0.0576
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0276 0.1273
Leishmania major hypothetical protein, conserved 0.0038 0.027 0.0969
Trichomonas vaginalis dullard protein, putative 0.0038 0.027 0.0266
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0024 0.0024
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.001 0.0023 0.0129
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0146 0.1248 0.1248
Loa Loa (eye worm) latrophilin receptor protein 2 0.0046 0.0348 0.0348
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0024 0.0033
Echinococcus granulosus dual specificity 0.0097 0.0807 0.1296
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0026 0.0162 0.0218
Echinococcus multilocularis dual specificity 0.0097 0.0807 0.1088
Plasmodium vivax SET domain protein, putative 0.0033 0.0229 0.2954
Loa Loa (eye worm) hypothetical protein 0.0046 0.0348 0.0348
Brugia malayi Pre-SET motif family protein 0.0033 0.0229 0.0229
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.001 0.0023 0.0089
Mycobacterium ulcerans lipase LipD 0.0038 0.0276 0.0254
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0008 0.0004 0.0006
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0024 0.0039
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0297 0.0476
Brugia malayi jmjC domain containing protein 0.0011 0.0025 0.0025
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0084 0.069 0.5
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0024 0.0033
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.001 0.0023 0.0139
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.001 0.0023 0.0129
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0276 0.0276
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0008 0.0004 0.0052
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.001 0.0023 0.0089
Leishmania major aldehyde dehydrogenase, putative 0.001 0.0023 0.0069
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0107 0.0896 0.1209
Echinococcus granulosus synaptojanin 1 0.0008 0.0004 0.0006
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0053 0.0413 0.0413
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.001 0.0023 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0231 0.2016 0.7331
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.0413 0.0663
Entamoeba histolytica hypothetical protein 0.0108 0.0909 0.5182
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0162 0.0576
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0024 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0757 0.2754
Brugia malayi jmjC domain containing protein 0.0011 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0011 0.0026 0.0022
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0055 0.0428 0.1986
Trypanosoma brucei DNA polymerase kappa, putative 0.0231 0.2016 0.7331
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.001 0.0023 0.0069
Loa Loa (eye worm) hypothetical protein 0.0037 0.0266 0.0266
Schistosoma mansoni DNA polymerase eta 0.0312 0.275 0.2748
Mycobacterium ulcerans hypothetical protein 0.0063 0.0496 0.0475
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0162 0.0158
Schistosoma mansoni hypothetical protein 0.0037 0.0266 0.0262
Schistosoma mansoni DNA helicase recq1 0.0011 0.003 0.0026
Trypanosoma brucei unspecified product 0.0139 0.1188 0.4321
Echinococcus multilocularis synaptojanin 1 0.0008 0.0004 0.0005
Plasmodium falciparum DNA repair protein REV1, putative 0.0063 0.0496 0.704
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.001 0.0023 0.0139
Leishmania major DNA polymerase kappa, putative 0.0063 0.0496 0.1793
Onchocerca volvulus 0.0258 0.2264 1
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.001 0.0023 0.0069
Loa Loa (eye worm) hypothetical protein 0.0038 0.0276 0.0276
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0303 0.0299
Echinococcus multilocularis caspase 2 0.0026 0.0162 0.0218
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0084 0.069 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0024 0.0024
Trypanosoma brucei DNA polymerase IV, putative 0.0224 0.1952 0.7096
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0297 0.0293
Brugia malayi Protein kinase domain containing protein 0.0097 0.0807 0.0807
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.001 0.0023 0.0089
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0018 0.0094 0.1211
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0011 0.0025 0.0021
Schistosoma mansoni glutaminase 0.1114 1 1
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0084 0.069 1
Trypanosoma cruzi DNA damage repair protein, putative 0.0063 0.0496 0.1793
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.001 0.0023 0.0036
Mycobacterium ulcerans DNA polymerase IV 0.0231 0.2016 0.1998
Schistosoma mansoni cpg binding protein 0.0031 0.0206 0.0202
Echinococcus granulosus peptidase Clp S14 family 0.0055 0.0428 0.0687
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0276 0.1273
Schistosoma mansoni jumonji domain containing protein 0.0011 0.0025 0.0021
Brugia malayi Pre-SET motif family protein 0.0227 0.1981 0.1981
Loa Loa (eye worm) hypothetical protein 0.0033 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0024
Brugia malayi ecdysteroid receptor 0.001 0.0024 0.0024
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0024 0.0021
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0004 0.0013
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0038 0.027 0.1465
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.001 0.0023 0.0023
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.001 0.0016 0.0021
Schistosoma mansoni DNA helicase recq5 0.0011 0.003 0.0026
Echinococcus multilocularis lysine specific demethylase 5A 0.004 0.0287 0.0387
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0024
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.001 0.0023 0.0082
Brugia malayi Bromodomain containing protein 0.004 0.0295 0.0295
Echinococcus granulosus jumonji domain containing 1A 0.0011 0.0025 0.004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0024 0.0024
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0024 0.0021
Echinococcus multilocularis jumonji domain containing 1A 0.0011 0.0025 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0229 0.0225
Brugia malayi glutaminase DH11.1 0.1114 1 1
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.001 0.0023 0.003
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0026 0.0026
Schistosoma mansoni aldehyde dehydrogenase 0.001 0.0023 0.0019
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.001 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0025
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0022
Toxoplasma gondii hypothetical protein 0.0029 0.0191 0.1181
Echinococcus multilocularis snurportin 1 0.0298 0.2622 0.3536
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0024 0.0024
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0162 0.0998
Trypanosoma brucei DNA polymerase kappa, putative 0.0231 0.2016 0.7331
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.001 0.0023 0.0129
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0038 0.027 0.0981
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0297 0.0275
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0115 0.0115
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0024 0.0039
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0024 0.0039
Schistosoma mansoni cpg binding protein 0.0032 0.0221 0.0218
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0084 0.069 0.4256
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0134 0.013
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0162 0.0998
Brugia malayi nuclear receptor NHR-88 0.001 0.0024 0.0024
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0084 0.069 0.4256
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.0598 0.0598
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0004 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0043 0.0553
Echinococcus granulosus FTZ F1 alpha 0.001 0.0024 0.0039
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0094 0.0775 0.4784
Mycobacterium tuberculosis Conserved protein 0.0038 0.0276 0.1273
Trypanosoma brucei DNA polymerase kappa, putative 0.0146 0.1253 0.4557
Brugia malayi steroid hormone receptor 0.001 0.0024 0.0024
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.0041 0.0065
Trypanosoma cruzi metacaspase, putative 0.0026 0.0162 0.0576
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0115 0.0406
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0162 0.0158
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0004 0.0004
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0297 0.0297
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0229 0.0225
Trypanosoma brucei DNA polymerase kappa, putative 0.0231 0.2016 0.7331
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0316 0.0427
Loa Loa (eye worm) hypothetical protein 0.0096 0.0802 0.0802
Trypanosoma cruzi DNA polymerase kappa, putative 0.0231 0.2016 0.7328
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0276 0.099
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0011 0.003 0.0424
Trypanosoma brucei DNA polymerase kappa, putative 0.0231 0.2016 0.7331
Entamoeba histolytica Ran family GTPase 0.0021 0.0115 0.0656
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0011 0.0025 0.0077
Leishmania major GTP-binding protein, putative 0.0021 0.0115 0.0406
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0212 0.0341
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0011 0.0026 0.0095
Brugia malayi ImpB/MucB/SamB family protein 0.0312 0.275 0.275
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0121 0.0121
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0191 0.247
Schistosoma mansoni peptidase Clp (S14 family) 0.0084 0.069 0.0686
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.001 0.0023 0.0089
Brugia malayi AF-10 protein 0.0011 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0025
Plasmodium falciparum phd finger protein, putative 0.0033 0.0225 0.3189
Echinococcus granulosus GPCR family 2 0.0046 0.0348 0.0559
Echinococcus granulosus histone acetyltransferase KAT2B 0.0094 0.0775 0.1245
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.001 0.0023 0.0019
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0024 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0024 0.0024
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.0598 0.2164
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0024
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0004 0.0004
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0024 0.0033
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0229 0.0309
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0008 0.0004 0.0052
Trypanosoma cruzi DNA polymerase kappa, putative 0.0231 0.2016 0.7328
Schistosoma mansoni aldehyde dehydrogenase 0.001 0.0023 0.0019
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.001 0.0023 0.0069
Echinococcus granulosus CTD small phosphatase protein like 0.0038 0.027 0.0433
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0025 0.0025
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0011 0.0025 0.0153
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0084 0.069 0.093
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.001 0.0023 0.0069
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0297 0.4269
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0038 0.027 0.348
Trypanosoma cruzi metacaspase, putative 0.0026 0.0162 0.0576
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0219 0.1907 0.2572
Schistosoma mansoni hypothetical protein 0.0696 0.6227 0.6225
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0024 0.0024
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0022
Echinococcus granulosus jumonji domain containing protein 0.0045 0.034 0.0547
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0024 0.0021
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0092 0.0568
Loa Loa (eye worm) hypothetical protein 0.0028 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0008 0.0004 0.0004
Brugia malayi beta-lactamase 0.0038 0.0276 0.0276
Brugia malayi PHD-finger family protein 0.0012 0.0042 0.0042
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0539 0.0539
Onchocerca volvulus Cell death protein 3 homolog 0.0026 0.0162 0.07
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0025 0.0025
Echinococcus multilocularis lysine specific demethylase 6a 0.0011 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0016
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0024
Mycobacterium tuberculosis Conserved protein 0.0038 0.0276 0.1273
Leishmania major DNA polymerase kappa, putative 0.0209 0.182 0.6612
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0162 0.0158
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0297 0.1066
Plasmodium falciparum DNase I-like protein, putative 0.0008 0.0004 0.0052
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0084 0.069 0.1108
Schistosoma mansoni phosphatidylserine receptor 0.0011 0.0025 0.0021
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0276 0.0272
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0162 0.0158
Trypanosoma brucei RNA editing exonuclease 2 0.0008 0.0004 0.0013
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0022
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0055 0.0428 0.6074
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0038 0.027 0.0266
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0004 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0807 0.0803
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0024 0.0092
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0008 0.0004 0.0013
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.003 0.003
Giardia lamblia Alcohol dehydrogenase 0.001 0.0023 0.0104
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0059 0.0216
Trypanosoma brucei aldehyde dehydrogenase, putative 0.001 0.0023 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0024 0.0024
Trypanosoma cruzi DNA polymerase eta, putative 0.0312 0.275 1
Schistosoma mansoni DNA polymerase IV / kappa 0.0063 0.0496 0.0493
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0162 0.0158
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.001 0.0023 0.003
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0134 0.013
Loa Loa (eye worm) RecQ helicase 0.0027 0.0173 0.0173
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0191 0.2717
Schistosoma mansoni hypothetical protein 0.0033 0.0225 0.0221
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0008 0.0004 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0024 0.0033
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0021
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0303 0.0303
Schistosoma mansoni aldehyde dehydrogenase 0.001 0.0023 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0024 0.0024
Leishmania major DNA polymerase eta, putative 0.0312 0.275 1
Echinococcus multilocularis caspase 0.0026 0.0162 0.0218
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0097 0.0807 0.0807
Brugia malayi hypothetical protein 0.0132 0.112 0.112
Plasmodium vivax metacaspase 1, putative 0.0026 0.0162 0.2086
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0115 0.0406
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0029 0.0191 0.2531
Brugia malayi beta-lactamase family protein 0.0038 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0016
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0276 0.1273
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0063 0.0496 0.1793
Brugia malayi mbt repeat family protein 0.0053 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0096 0.0802 0.0802
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0182 0.0245
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.001 0.0007
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.0413 0.0413
Echinococcus multilocularis caspase 8 0.0026 0.0162 0.0218
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0004 0.0004
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.2622 0.2622
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0024 0.0024
Schistosoma mansoni bromodomain containing protein 0.001 0.0016 0.0012
Leishmania major DNA damage repair protein, putative 0.0063 0.0496 0.1793
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0757 0.2754
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0297 0.3825
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0008 0.0004 0.0013
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0004 0.0004
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0038 0.027 0.3827
Trypanosoma brucei DNA polymerase kappa, putative 0.0146 0.1253 0.4557
Onchocerca volvulus Huntingtin homolog 0.0132 0.112 0.4938
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0276 0.0272
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0162 0.0158
Leishmania major aldehyde dehydrogenase, putative 0.001 0.0023 0.0069
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0026 0.0162 0.0158
Echinococcus granulosus peregrin 0.004 0.0295 0.0474
Entamoeba histolytica hypothetical protein 0.0097 0.0807 0.4597
Schistosoma mansoni thyroid hormone receptor 0.001 0.0024 0.0021
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0107 0.0896 0.144
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.001 0.0023 0.0089
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0276 0.0272
Echinococcus granulosus snurportin 1 0.0298 0.2622 0.4211
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0276 0.1273
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.0132 0.112 0.112
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0046 0.0348 0.0348
Echinococcus granulosus dna polymerase kappa 0.0231 0.2016 0.3238
Brugia malayi latrophilin 2 splice variant baaae 0.01 0.0833 0.0833
Trichomonas vaginalis set domain proteins, putative 0.0258 0.2264 0.2261
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0297 0.0293
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0276 0.1273
Mycobacterium ulcerans aldehyde dehydrogenase 0.0187 0.1621 0.1602
Onchocerca volvulus 0.0038 0.0276 0.1203
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0162 0.0158
Plasmodium vivax SET domain containing protein 0.001 0.0017 0.0217
Plasmodium falciparum metacaspase 1 0.0026 0.0162 0.2295
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0097 0.0807 0.2924
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0009 0.0012
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.0598 0.0595
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0202 0.1755 0.1752
Onchocerca volvulus 0.0033 0.0229 0.0997
Trypanosoma brucei DNA damage repair protein, putative 0.0063 0.0496 0.1804
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0598 0.2164
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0084 0.069 0.9787

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) > 64 ug ml-1 Antibacterial activity against tol C pump knockout Escherichia coli CAG12184 ChEMBL. 20356737

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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