Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0131 | 0.0131 |
Onchocerca volvulus | 0.0041 | 0.0387 | 0.1317 | |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0135 | 0.0396 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0387 | 0.1099 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.009 | 0.0103 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0387 | 0.5414 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0003 | 0.0003 |
Mycobacterium leprae | TWO COMPONENT SENSOR HISTIDINE KINASE PRRB | 0.0014 | 0.0048 | 0.0278 |
Brugia malayi | PHD-finger family protein | 0.0027 | 0.0209 | 0.0614 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0014 | 0.0048 | 0.0141 |
Trypanosoma brucei | heat shock protein, putative | 0.0068 | 0.0715 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0086 | 0.0124 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0065 | 0.0681 | 0.1999 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.007 | 0.0205 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0048 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0098 | 0.0289 |
Schistosoma mansoni | phd/f-box containing protein | 0.0016 | 0.0079 | 0.009 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.009 | 0.0103 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0448 | 0.0511 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0003 | 0.0003 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0066 | 0.0195 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0387 | 0.0441 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0098 | 0.0163 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0099 | 0.1106 | 0.126 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0003 | 0.001 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0143 | 0.0143 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0635 | 0.1865 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0058 | 0.0589 | 0.0671 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0021 | 0.0131 | 0.015 |
Onchocerca volvulus | 0.0021 | 0.0131 | 0.0447 | |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0041 | 0.0387 | 0.1138 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0003 | 0.0004 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0173 | 0.0508 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0003 | 0.0004 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0099 | 0.1106 | 0.3249 |
Loa Loa (eye worm) | endoplasmin | 0.0068 | 0.0715 | 0.2101 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0079 | 0.0472 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0305 | 0.3647 | 1 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0039 | 0.0354 | 0.0354 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0305 | 0.3647 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0079 | 0.0233 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0014 | 0.0048 | 0.0669 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.3647 | 1 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0016 | 0.0079 | 0.0079 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0131 | 0.0386 |
Echinococcus granulosus | tumor protein p63 | 0.0694 | 0.8456 | 0.9634 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0014 | 0.0048 | 0.0141 |
Echinococcus multilocularis | muscleblind protein | 0.0156 | 0.1804 | 0.1804 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0016 | 0.0079 | 0.1109 |
Echinococcus granulosus | tar DNA binding protein | 0.0215 | 0.254 | 0.2894 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0135 | 0.0153 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.027 | 0.3776 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0016 | 0.0079 | 0.1109 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0068 | 0.0715 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0003 | 0.001 |
Mycobacterium leprae | Probable two-component sensor kinase | 0.0014 | 0.0048 | 0.0278 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0215 | 0.254 | 0.7461 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0405 | 0.0405 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0405 | 0.1109 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0387 | 0.0441 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.3647 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.027 | 0.0794 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0475 | 0.1395 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0387 | 0.1099 |
Brugia malayi | Probable DNA topoisomerase II | 0.0014 | 0.0048 | 0.0141 |
Trichomonas vaginalis | set domain proteins, putative | 0.0248 | 0.294 | 0.8063 |
Mycobacterium ulcerans | lipase LipD | 0.0041 | 0.0387 | 0.1138 |
Schistosoma mansoni | tar DNA-binding protein | 0.0215 | 0.254 | 0.2894 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0014 | 0.0048 | 0.0669 |
Echinococcus multilocularis | expressed conserved protein | 0.0093 | 0.1032 | 0.1032 |
Schistosoma mansoni | endoplasmin | 0.0068 | 0.0715 | 0.0815 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0003 | 0.0004 |
Schistosoma mansoni | tar DNA-binding protein | 0.0215 | 0.254 | 0.2894 |
Mycobacterium ulcerans | two component sensory transduction histidine kinase MtrB | 0.0014 | 0.0048 | 0.0141 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0039 | 0.0354 | 0.0971 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.002 | 0.0124 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0354 | 0.104 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0173 | 0.0508 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.007 | 0.0973 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0386 | 0.0439 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0003 | 0.001 |
Plasmodium vivax | heat shock protein 90, putative | 0.0028 | 0.0221 | 0.3084 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0427 | 0.5152 | 0.5152 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0065 | 0.0681 | 0.0775 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0066 | 0.0195 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0149 | 0.1719 | 0.5047 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0405 | 0.0461 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0039 | 0.0354 | 0.0403 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.007 | 0.007 |
Brugia malayi | TAR-binding protein | 0.0215 | 0.254 | 0.7461 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0016 | 0.0079 | 0.009 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.006 | 0.0617 | 0.1812 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0039 | 0.0354 | 0.0354 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0003 | 0.001 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Schistosoma mansoni | endoplasmin | 0.0068 | 0.0715 | 0.0815 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.006 | 0.0617 | 0.8524 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0014 | 0.0048 | 0.0669 |
Echinococcus granulosus | phd:f box containing protein | 0.0016 | 0.0079 | 0.009 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.004 | 0.0372 | 0.5199 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0173 | 0.0475 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0056 | 0.0567 | 0.1666 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.3647 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0066 | 0.0066 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.0068 | 0.0952 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0006 | 0.0017 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0041 | 0.0387 | 0.1099 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0098 | 0.0289 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0248 | 0.0282 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0173 | 0.1876 |
Trypanosoma brucei | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0014 | 0.0048 | 0.0669 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0016 | 0.0079 | 0.009 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.007 | 0.0973 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.0688 | 0.0784 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0003 | 0.0004 |
Echinococcus granulosus | heat shock protein 90 | 0.0068 | 0.0715 | 0.0815 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1106 | 0.3249 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0354 | 0.0971 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.018 | 0.0205 |
Onchocerca volvulus | 0.0021 | 0.0131 | 0.0447 | |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.007 | 0.0973 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0098 | 0.0289 |
Schistosoma mansoni | lipoxygenase | 0.0058 | 0.0589 | 0.0671 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0028 | 0.0221 | 0.0221 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0066 | 0.0076 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0003 | 0.001 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0247 | 0.0282 |
Mycobacterium ulcerans | two component regulator - sensor kinase | 0.0014 | 0.0048 | 0.0141 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0239 | 0.2829 | 0.2829 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0635 | 0.0724 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0016 | 0.0079 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0479 | 0.0546 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0387 | 0.1062 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0014 | 0.0048 | 0.0131 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.006 | 0.0617 | 0.1842 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0003 | 0.001 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0016 | 0.0079 | 0.009 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0173 | 0.1876 |
Trypanosoma cruzi | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0014 | 0.0048 | 0.0669 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0173 | 0.0508 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0014 | 0.0048 | 0.0669 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0173 | 0.0508 |
Mycobacterium ulcerans | beta-lactamase | 0.0041 | 0.0387 | 0.1138 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.076 | 0.2232 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0014 | 0.0048 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0405 | 0.1188 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0173 | 0.0508 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0003 | 0.001 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0003 | 0.0011 |
Schistosoma mansoni | hypothetical protein | 0.0427 | 0.5152 | 0.587 |
Echinococcus multilocularis | tumor protein p63 | 0.0694 | 0.8456 | 0.8456 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0003 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0173 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0387 | 0.1138 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0068 | 0.0715 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0448 | 0.0448 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0014 | 0.0048 | 0.0669 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0173 | 0.0508 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0405 | 0.1188 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0021 | 0.0131 | 0.1836 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0014 | 0.0048 | 0.0669 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0028 | 0.0221 | 0.3084 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0448 | 0.0511 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0286 | 0.084 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0386 | 0.0439 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0003 | 0.001 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0068 | 0.0715 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Trichomonas vaginalis | sensory transduction histidine kinase, putative | 0.0014 | 0.0048 | 0.0131 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.018 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0098 | 0.0289 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0448 | 0.0511 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0173 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.001 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0635 | 0.1865 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0101 | 0.1125 | 0.1282 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.0636 | 0.1867 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0003 | 0.001 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0003 | 0.001 |
Onchocerca volvulus | 0.0102 | 0.1133 | 0.3853 | |
Brugia malayi | hypothetical protein | 0.0239 | 0.2829 | 0.8309 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0003 | 0.001 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0014 | 0.0048 | 0.0131 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.007 | 0.007 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0041 | 0.0387 | 0.1138 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0635 | 0.8876 |
Echinococcus multilocularis | RUN | 0.0021 | 0.0131 | 0.0131 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0003 | 0.0004 |
Plasmodium falciparum | heat shock protein 90 | 0.0068 | 0.0715 | 1 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0039 | 0.0354 | 0.0971 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0387 | 0.1062 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0003 | 0.0004 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0003 | 0.0004 |
Schistosoma mansoni | loxhd1 | 0.0021 | 0.0131 | 0.015 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0068 | 0.0078 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0028 | 0.0221 | 0.0251 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0003 | 0.0004 |
Schistosoma mansoni | protein phosphatase 2C | 0.0016 | 0.0079 | 0.009 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0003 | 0.0003 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0387 | 0.5414 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.007 | 0.0973 |
Onchocerca volvulus | 0.0041 | 0.0387 | 0.1317 | |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0066 | 0.0195 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0014 | 0.0048 | 0.0048 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0479 | 0.0479 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0003 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1804 | 0.5297 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0066 | 0.0195 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0061 | 0.0636 | 0.0636 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.0014 | 0.0048 | 0.0055 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0014 | 0.0048 | 0.0669 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0041 | 0.0387 | 0.1099 |
Echinococcus granulosus | replication factor c subunit 1 | 0.001 | 0.00000034704 | 0.00000039539 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0173 | 0.0508 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0054 | 0.0545 | 0.1608 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0003 | 0.001 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.009 | 0.009 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0264 | 0.3137 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0003 | 0.0003 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0149 | 0.1719 | 0.5408 |
Brugia malayi | heat shock protein 90 | 0.0068 | 0.0715 | 0.2101 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0016 | 0.0079 | 0.1109 |
Echinococcus granulosus | heat shock protein 90 | 0.0054 | 0.0545 | 0.0621 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0448 | 0.0448 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0041 | 0.0387 | 0.1099 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.027 | 0.027 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0292 | 0.0333 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.0292 | 0.0333 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0014 | 0.0048 | 0.0669 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0405 | 0.0461 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0003 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0098 | 0.0289 |
Trichomonas vaginalis | endoplasmin, putative | 0.0042 | 0.0391 | 0.1073 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0048 | 0.0141 |
Mycobacterium leprae | Probable two component sensor kinase MprB | 0.0014 | 0.0048 | 0.0278 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0068 | 0.0952 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0016 | 0.0079 | 0.1109 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0014 | 0.0048 | 0.0141 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0039 | 0.0354 | 0.4948 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0003 | 0.0004 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0003 | 0.0004 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0448 | 0.1316 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0003 | 0.0003 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0054 | 0.0545 | 0.7614 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0066 | 0.0076 |
Mycobacterium ulcerans | two component sensor histidine kinase DevS | 0.0014 | 0.0048 | 0.0141 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0098 | 0.1373 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.0387 | 0.1138 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0014 | 0.0048 | 0.0669 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.009 | 0.0103 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0068 | 0.0303 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | DNA gyrase subunit B | 0.0014 | 0.0048 | 0.0141 |
Schistosoma mansoni | DNA topoisomerase II | 0.0014 | 0.0048 | 0.0055 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0079 | 0.0233 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0041 | 0.0387 | 0.1099 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0066 | 0.0066 |
Schistosoma mansoni | tar DNA-binding protein | 0.0215 | 0.254 | 0.2894 |
Echinococcus multilocularis | tar DNA binding protein | 0.0215 | 0.254 | 0.254 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0099 | 0.1106 | 0.1106 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0131 | 0.015 |
Brugia malayi | kinase, mitochondrial precursor | 0.0014 | 0.0048 | 0.0141 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0086 | 0.0124 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.007 | 0.0327 |
Mycobacterium ulcerans | putative regultory protein | 0.0014 | 0.0048 | 0.0141 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Mycobacterium ulcerans | two component system membrane associated sensor kinase | 0.0014 | 0.0048 | 0.0141 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0003 | 0.001 |
Onchocerca volvulus | 0.0024 | 0.0173 | 0.0589 | |
Mycobacterium tuberculosis | Probable hydrolase | 0.0041 | 0.0387 | 0.1099 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0356 | 0.1046 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0003 | 0.001 |
Brugia malayi | Hsp90 protein | 0.0028 | 0.0221 | 0.0648 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0643 | 0.0733 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.001 | 0.00000034704 | 0.00000095168 |
Loa Loa (eye worm) | glutaminase 2 | 0.0285 | 0.3405 | 1 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.00000034704 | 0.00000095168 |
Mycobacterium leprae | Probable lipase LipE | 0.0041 | 0.0387 | 0.2254 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0054 | 0.0545 | 0.317 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0066 | 0.0076 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0131 | 0.0131 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0098 | 0.0289 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.018 | 0.0205 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0028 | 0.0221 | 0.3084 |
Leishmania major | heat shock protein, putative | 0.0028 | 0.0221 | 0.2588 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0039 | 0.0354 | 0.0403 |
Echinococcus granulosus | RUN | 0.0021 | 0.0131 | 0.015 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.0014 | 0.0048 | 0.0669 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.027 | 0.0308 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0003 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1804 | 0.5297 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0014 | 0.0048 | 0.0048 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0387 | 0.1062 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0041 | 0.0387 | 0.1138 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0003 | 0.0004 |
Brugia malayi | Pre-SET motif family protein | 0.0218 | 0.2569 | 0.7546 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0014 | 0.0048 | 0.0669 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0173 | 0.0508 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0041 | 0.0387 | 0.0441 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0475 | 0.1395 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0142 | 0.1634 | 0.1861 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0143 | 0.0162 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0014 | 0.0048 | 0.0163 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0131 | 0.015 |
Brugia malayi | Muscleblind-like protein | 0.0156 | 0.1804 | 0.5298 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0173 | 0.0475 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0016 | 0.0079 | 0.1109 |
Schistosoma mansoni | heat shock protein | 0.0068 | 0.0715 | 0.0815 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Plasmodium vivax | heat shock protein 86, putative | 0.0068 | 0.0715 | 1 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.0014 | 0.0048 | 0.0131 |
Schistosoma mansoni | lipoxygenase | 0.0021 | 0.0131 | 0.015 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.3647 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.007 | 0.0079 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0292 | 0.0333 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.0635 | 0.0724 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0479 | 0.0546 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0003 | 0.001 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0066 | 0.0076 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0068 | 0.0715 | 0.1962 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0068 | 0.0715 | 0.1962 |
Onchocerca volvulus | 0.001 | 0.0003 | 0.0011 | |
Echinococcus granulosus | dnaJ subfamily B | 0.0427 | 0.5152 | 0.587 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0387 | 0.1062 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.3647 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0475 | 0.1395 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0448 | 0.1316 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0173 | 0.0508 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0003 | 0.0011 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0012 | 0.0028 | 0.0083 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.0387 | 0.5414 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.3647 | 1 |
Trichomonas vaginalis | two component sensor and regulator histidine kinase bacteria, putative | 0.0014 | 0.0048 | 0.0131 |
Echinococcus granulosus | endoplasmin | 0.0054 | 0.0545 | 0.0621 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0028 | 0.0221 | 0.3084 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0098 | 1 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0016 | 0.0079 | 0.0079 |
Plasmodium vivax | endoplasmin, putative | 0.0068 | 0.0715 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0387 | 0.1062 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.006 | 0.0617 | 0.0703 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0014 | 0.0048 | 0.0669 |
Trypanosoma brucei | developmentally regulated phosphoprotein | 0.0014 | 0.0048 | 0.0669 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.001 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0239 | 0.2829 | 0.3223 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0014 | 0.0048 | 0.0131 |
Loa Loa (eye worm) | glutaminase | 0.0285 | 0.3405 | 1 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0014 | 0.0048 | 0.0669 |
Brugia malayi | beta-lactamase | 0.0041 | 0.0387 | 0.1138 |
Schistosoma mansoni | tar DNA-binding protein | 0.0215 | 0.254 | 0.2894 |
Brugia malayi | glutaminase DH11.1 | 0.0285 | 0.3405 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0041 | 0.0387 | 0.1062 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0028 | 0.0221 | 0.0648 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0003 | 0.0004 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0173 | 0.0508 |
Schistosoma mansoni | jumonji domain containing protein | 0.0016 | 0.0079 | 0.009 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0003 | 0.001 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0098 | 0.0287 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.3647 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0068 | 0.0715 | 1 |
Onchocerca volvulus | 0.0248 | 0.294 | 1 | |
Echinococcus granulosus | microtubule associated protein 2 | 0.072 | 0.8777 | 1 |
Mycobacterium leprae | PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 | 0.0014 | 0.0048 | 0.0278 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0098 | 0.1373 |
Wolbachia endosymbiont of Brugia malayi | signal transduction histidine kinase and receiver | 0.0014 | 0.0048 | 0.0878 |
Echinococcus granulosus | heat shock protein | 0.0068 | 0.0715 | 0.0815 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0079 | 0.0233 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0387 | 0.1099 |
Loa Loa (eye worm) | doublecortin family protein | 0.0021 | 0.0131 | 0.0386 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0039 | 0.0354 | 0.0971 |
Trichomonas vaginalis | heat shock protein, putative | 0.0028 | 0.0221 | 0.0605 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0016 | 0.0079 | 0.009 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0386 | 0.0439 |
Mycobacterium ulcerans | two component sensor histidine kinase SenX3 | 0.0014 | 0.0048 | 0.0141 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0173 | 0.0508 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0173 | 0.0508 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0003 | 0.0004 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0016 | 0.0079 | 0.009 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0173 | 0.1007 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0014 | 0.0048 | 0.0048 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0247 | 0.0727 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0039 | 0.0354 | 0.4948 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0405 | 0.1188 |
Mycobacterium ulcerans | two component sensor kinase MprB | 0.0014 | 0.0048 | 0.0141 |
Echinococcus multilocularis | heat shock protein 90 | 0.0054 | 0.0545 | 0.0545 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.006 | 0.0617 | 0.1812 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0099 | 0.1106 | 0.3033 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0039 | 0.0354 | 0.0403 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0286 | 0.084 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0003 | 0.001 |
Schistosoma mansoni | heat shock protein | 0.0028 | 0.0221 | 0.0251 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0215 | 0.254 | 0.7461 |
Mycobacterium ulcerans | two component sensor histidine kinase TrcS | 0.0014 | 0.0048 | 0.0141 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0014 | 0.0048 | 0.0669 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0003 | 0.001 |
Echinococcus multilocularis | heat shock protein | 0.0068 | 0.0715 | 0.0715 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.007 | 0.007 |
Trypanosoma brucei | heat shock protein, putative | 0.0068 | 0.0715 | 1 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0016 | 0.0079 | 0.1109 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0041 | 0.0387 | 0.1099 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0006 | 0.0007 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0387 | 0.1138 |
Echinococcus multilocularis | endoplasmin | 0.0054 | 0.0545 | 0.0545 |
Echinococcus multilocularis | heat shock protein 90 | 0.0068 | 0.0715 | 0.0715 |
Schistosoma mansoni | jumonji domain containing protein | 0.0061 | 0.0636 | 0.0724 |
Wolbachia endosymbiont of Brugia malayi | membrane associated signal transduction histidine kinase | 0.0014 | 0.0048 | 0.0878 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0061 | 0.0636 | 0.0636 |
Trichomonas vaginalis | heat shock protein, putative | 0.0054 | 0.0545 | 0.1494 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0039 | 0.0354 | 0.0971 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0355 | 0.1043 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0079 | 0.0233 |
Onchocerca volvulus | 0.0032 | 0.027 | 0.0919 | |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0475 | 0.1395 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0326 | 0.0371 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0068 | 0.0715 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0131 | 0.015 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0014 | 0.0048 | 0.0131 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0068 | 0.0715 | 1 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0039 | 0.0354 | 0.104 |
Mycobacterium ulcerans | two component system response phosphate sensor kinase, PhoR | 0.0014 | 0.0048 | 0.0141 |
Trichomonas vaginalis | sensor histidine kinase, putative | 0.0014 | 0.0048 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.001 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0068 | 0.0715 | 0.1962 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0003 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0387 | 0.1138 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0173 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.001 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0387 | 0.1138 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.001 | 0.00000034704 | 0.00000039539 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0305 | 0.3647 | 1 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0068 | 0.0952 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0041 | 0.0387 | 0.0387 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.007 | 0.0205 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0068 | 0.0715 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.001 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0131 | 0.0386 |
Loa Loa (eye worm) | TAR-binding protein | 0.0215 | 0.254 | 0.7461 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0054 | 0.0545 | 1 |
Schistosoma mansoni | heat shock protein | 0.0068 | 0.0715 | 0.0815 |
Trichomonas vaginalis | heat shock protein, putative | 0.0068 | 0.0715 | 0.1962 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.027 | 0.3776 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0028 | 0.0221 | 0.3084 |
Trichomonas vaginalis | heat shock protein, putative | 0.0054 | 0.0545 | 0.1494 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0003 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0523 | 0.1537 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.072 | 0.8777 | 0.8777 |
Onchocerca volvulus | 0.0049 | 0.0479 | 0.163 | |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0014 | 0.0048 | 0.0055 |
Loa Loa (eye worm) | RNA binding protein | 0.0215 | 0.254 | 0.7461 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0405 | 0.0405 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0079 | 0.0233 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.0014 | 0.0048 | 0.0878 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0143 | 0.0162 |
Plasmodium falciparum | DNA gyrase subunit B | 0.0014 | 0.0048 | 0.0669 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0016 | 0.007 | 0.0071 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0039 | 0.0354 | 0.0403 |
Trypanosoma cruzi | heat shock protein, putative | 0.0028 | 0.0221 | 0.3084 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.027 | 0.0308 |
Onchocerca volvulus | 0.0011 | 0.0014 | 0.0047 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0635 | 0.1865 |
Onchocerca volvulus | 0.003 | 0.0247 | 0.0842 | |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.007 | 0.0079 |
Giardia lamblia | Pms1-like protein | 0.0014 | 0.0048 | 0.0131 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0028 | 0.0221 | 0.3084 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0218 | 0.2569 | 0.7546 |
Mycobacterium ulcerans | sensor kinase from two component regulatory system | 0.0014 | 0.0048 | 0.0141 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.007 | 0.007 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0068 | 0.0715 | 1 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0039 | 0.0354 | 0.0354 |
Loa Loa (eye worm) | beta-lactamase | 0.0041 | 0.0387 | 0.1138 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0131 | 0.0386 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0003 | 0.0004 |
Onchocerca volvulus | 0.0041 | 0.0387 | 0.1317 | |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0247 | 0.0727 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1133 | 0.3327 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0173 | 0.1007 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0003 | 0.001 |
Plasmodium falciparum | DNA topoisomerase VI, b subunit, putative | 0.0014 | 0.0048 | 0.0669 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0003 | 0.0004 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0003 | 0.0004 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0054 | 0.0545 | 0.7614 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.006 | 0.0617 | 0.0703 |
Echinococcus multilocularis | phd:f box containing protein | 0.0016 | 0.0079 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0066 | 0.0076 |
Plasmodium vivax | JmjC domain containing protein | 0.0016 | 0.0079 | 0.1109 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0386 | 0.1133 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0079 | 0.0233 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0068 | 0.0715 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.007 | 0.0973 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0173 | 0.0405 |
Toxoplasma gondii | ABC1 family protein | 0.0041 | 0.0387 | 0.5414 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0131 | 0.015 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0479 | 0.1407 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.001 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0003 | 0.0004 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0079 | 0.0233 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0086 | 0.0124 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0054 | 0.0545 | 0.7443 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0028 | 0.0221 | 0.0605 |
Trichomonas vaginalis | heat shock protein, putative | 0.0042 | 0.0391 | 0.1073 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0448 | 0.0511 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0039 | 0.0354 | 0.4948 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0003 | 0.0004 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0387 | 0.5414 |
Mycobacterium ulcerans | glutaminase | 0.0285 | 0.3405 | 1 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.006 | 0.0617 | 0.0617 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0387 | 0.1138 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0086 | 0.0124 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0003 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0387 | 0.1138 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0068 | 0.0715 | 0.2101 |
Brugia malayi | RNA binding protein | 0.0215 | 0.254 | 0.7461 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0039 | 0.0354 | 0.0403 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0149 | 0.1719 | 1 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.007 | 0.0205 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0156 | 0.1804 | 0.1804 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0058 | 0.0589 | 0.0589 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.001 | 0.00000034704 | 0.00000095168 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0068 | 0.0078 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.002 | 0.0124 | 0.0142 |
Mycobacterium leprae | conserved hypothetical protein | 0.0041 | 0.0387 | 0.2254 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0054 | 0.0545 | 0.1494 |
Schistosoma mansoni | polycystin 1-related | 0.0021 | 0.0131 | 0.015 |
Brugia malayi | jmjC domain containing protein | 0.0065 | 0.0681 | 0.1999 |
Trypanosoma brucei | heat shock protein, putative | 0.0068 | 0.0715 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.006 | 0.0617 | 0.1812 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.006 | 0.0623 | 0.8701 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0079 | 0.0233 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0387 | 0.5085 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0079 | 0.0233 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | Pyruvate dehydrogenase lipoamide kinase | 0.0014 | 0.0048 | 0.0055 |
Mycobacterium ulcerans | two component sensor histidine kinase PrrB | 0.0014 | 0.0048 | 0.0141 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0305 | 0.3647 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0054 | 0.0545 | 0.1494 |
Brugia malayi | Bromodomain containing protein | 0.0077 | 0.0834 | 0.2451 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0003 | 0.001 |
Treponema pallidum | chemotaxis histidine kinase (cheA) | 0.0014 | 0.0048 | 0.0131 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0131 | 0.015 |
Echinococcus granulosus | muscleblind protein | 0.0156 | 0.1804 | 0.2055 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.007 | 0.0973 |
Trypanosoma brucei | heat shock protein, putative | 0.0068 | 0.0715 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0239 | 0.2829 | 0.8309 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.0292 | 0.0292 |
Plasmodium vivax | heat shock protein, putative | 0.0028 | 0.0221 | 0.3084 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0048 | 0.0141 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0068 | 0.0715 | 1 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0054 | 0.0545 | 0.0621 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.0173 | 0.0475 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0014 | 0.0048 | 0.487 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0049 | 0.0483 | 0.0483 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0003 | 0.001 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0003 | 0.001 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.00000034704 | 0.00000095168 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0049 | 0.0483 | 0.055 |
Treponema pallidum | heat shock protein 90 | 0.0054 | 0.0545 | 0.1494 |
Plasmodium vivax | hypothetical protein, conserved | 0.0014 | 0.0048 | 0.0669 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0066 | 0.0076 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0003 | 0.0003 |
Toxoplasma gondii | ATPase, AAA family protein | 0.001 | 0.00000034704 | 0.0000048504 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0068 | 0.0715 | 1 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0028 | 0.0221 | 0.075 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0041 | 0.0387 | 0.1138 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0014 | 0.0048 | 0.487 |
Trypanosoma brucei | heat shock protein, putative | 0.0068 | 0.0715 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.0635 | 0.1901 |
Plasmodium falciparum | endoplasmin, putative | 0.0042 | 0.0391 | 0.547 |
Leishmania major | heat shock protein 83-1 | 0.0068 | 0.0715 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0131 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0483 | 0.1419 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0065 | 0.0681 | 0.0775 |
Trypanosoma brucei | heat shock protein, putative | 0.0068 | 0.0715 | 1 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0014 | 0.0048 | 0.487 |
Schistosoma mansoni | microtubule-associated protein tau | 0.072 | 0.8777 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.007 | 0.0973 |
Trypanosoma cruzi | developmentally regulated phosphoprotein, putative | 0.0014 | 0.0048 | 0.0669 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0065 | 0.0677 | 0.0771 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0061 | 0.0636 | 0.0724 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0014 | 0.0048 | 0.0131 |
Echinococcus granulosus | expressed conserved protein | 0.0093 | 0.1032 | 0.1175 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.007 | 0.0973 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0054 | 0.0545 | 0.16 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0003 | 0.001 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0326 | 0.0326 |
Schistosoma mansoni | tar DNA-binding protein | 0.0215 | 0.254 | 0.2894 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0041 | 0.0387 | 0.1099 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0066 | 0.0066 |
Brugia malayi | Endoplasmin precursor | 0.0068 | 0.0715 | 0.2101 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0102 | 0.1133 | 0.1291 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0049 | 0.0483 | 0.055 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0014 | 0.0048 | 0.0163 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0066 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0431 | 0.1265 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0386 | 0.0439 |
Brugia malayi | Doublecortin family protein | 0.0021 | 0.0131 | 0.0386 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0173 | 0.1876 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0006 | 0.0006 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0286 | 0.0326 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0635 | 0.0724 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0003 | 0.0004 |
Trichomonas vaginalis | glutaminase, putative | 0.0285 | 0.3405 | 0.9337 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0003 | 0.001 |
Giardia lamblia | Grp94/Hsp90 | 0.0054 | 0.0545 | 0.1494 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0021 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0387 | 0.1138 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.001 | 0.00000034704 | 0.00000034704 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.0635 | 0.8796 |
Trichomonas vaginalis | mismatch repair protein Mlh1C (mutL homolog) | 0.0014 | 0.0048 | 0.0131 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.3647 | 1 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0021 | 0.0131 | 0.1836 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0049 | 0.0483 | 0.055 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0405 | 0.0461 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0039 | 0.0354 | 0.4586 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0079 | 0.0233 |
Trypanosoma brucei | heat shock protein, putative | 0.0068 | 0.0715 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0065 | 0.0681 | 0.0775 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0003 | 0.0004 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0643 | 0.0643 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0142 | 0.1634 | 0.1634 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0014 | 0.0048 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.001 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0387 | 0.1138 |
Schistosoma mansoni | glutaminase | 0.0285 | 0.3405 | 0.3879 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0448 | 0.0511 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (ADMET) | < 10 mg/kg/day | Toxicity in iv bid dosed CD-1 mouse after 5 days | ChEMBL. | 21855338 |
CL (ADMET) | = 31.6 ml/min.kg | Plasma clearance in BALB/c mouse at 2 mg/kg, iv by LC/MS/MS | ChEMBL. | 21855338 |
F (ADMET) | = 1.6 % | Oral bioavailability in BALB/c mouse at 10 mg/kg by LC/MS/MS | ChEMBL. | 21855338 |
IC50 (ADMET) | > 250 uM | Cytotoxicity against human A549 cells after 48 hrs by MTS assay | ChEMBL. | 21855338 |
Inhibition (ADMET) | = -8 % | Inhibition of CYP1A2 at 10 uM | ChEMBL. | 21855338 |
Inhibition (ADMET) | = 10 % | Inhibition of CYP2D6 at 10 uM | ChEMBL. | 21855338 |
Inhibition (ADMET) | = 15 % | Inhibition of CYP2C9 at 10 uM | ChEMBL. | 21855338 |
Inhibition (ADMET) | = 25 % | Inhibition of CYP2C19 at 10 uM | ChEMBL. | 21855338 |
Inhibition (ADMET) | = 27 % | Inhibition of CYP3A4 at 10 uM | ChEMBL. | 21855338 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.