Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.042 | 0.0566 |
Echinococcus granulosus | lamin | 0.0027 | 0.0764 | 0.0604 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.004 | 0.1581 | 0.1436 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0019 | 0.028 | 0.0113 |
Schistosoma mansoni | nuclear receptor | 0.0019 | 0.028 | 0.0113 |
Onchocerca volvulus | Bile acid receptor homolog | 0.004 | 0.1581 | 1 |
Brugia malayi | conserved hypotetical protein | 0.0019 | 0.028 | 0.0378 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0326 | 0.0145 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.004 | 0.1581 | 0.2132 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.004 | 0.1581 | 0.2132 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.017 | 0.0229 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.004 | 0.1581 | 0.2132 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.014 | 0.772 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.014 | 0.772 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0019 | 0.028 | 0.0113 |
Schistosoma mansoni | nuclear hormone receptor | 0.0019 | 0.028 | 0.0113 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0326 | 0.0043 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0798 | 0.2272 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0019 | 0.028 | 0.0113 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0326 | 0.044 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.004 | 0.1581 | 0.2132 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.004 | 0.1581 | 0.1436 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0798 | 0.2272 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.017 | 0.0229 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.1389 | 0.1873 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0126 | 0.6856 | 0.8837 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0326 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.004 | 0.1581 | 0.2132 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.004 | 0.1581 | 0.2132 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0019 | 0.028 | 0.0113 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.004 | 0.1581 | 0.1436 |
Brugia malayi | steroid hormone receptor | 0.004 | 0.1581 | 0.2132 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0764 | 0.0604 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.004 | 0.1581 | 0.1436 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0103 | 0.5447 | 0.7344 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0764 | 0.0604 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0764 | 0.103 |
Plasmodium falciparum | glutathione reductase | 0.0055 | 0.2511 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.244 | 0.3289 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0103 | 0.5447 | 0.5369 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0798 | 0.2272 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1581 | 0.2132 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0798 | 0.2272 |
Brugia malayi | hypothetical protein | 0.0039 | 0.1507 | 0.2031 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0055 | 0.2511 | 0.2382 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0326 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0734 | 0.0989 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0019 | 0.0294 | 0.5 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0019 | 0.028 | 0.0378 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0021 | 0.042 | 0.0254 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.004 | 0.1581 | 0.1436 |
Brugia malayi | TAR-binding protein | 0.0135 | 0.7417 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.042 | 0.0566 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.004 | 0.1581 | 0.1436 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.244 | 0.3289 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0125 | 0.6834 | 0.9214 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.042 | 0.0566 |
Schistosoma mansoni | lamin | 0.0027 | 0.0764 | 0.0604 |
Brugia malayi | nuclear receptor NHR-67 | 0.0019 | 0.028 | 0.0378 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0019 | 0.028 | 0.0113 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.004 | 0.1581 | 0.2132 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.004 | 0.1581 | 0.2132 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0103 | 0.5447 | 0.7344 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.244 | 0.3289 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1581 | 0.2132 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0326 | 0.0145 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0019 | 0.028 | 0.0378 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0326 | 0.0145 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0021 | 0.042 | 0.0254 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0019 | 0.028 | 0.0113 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0326 | 0.016 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.004 | 0.1581 | 0.2132 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0764 | 0.103 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0019 | 0.0294 | 0.0127 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0019 | 0.028 | 0.0113 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0764 | 0.0604 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.004 | 0.1581 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0019 | 0.028 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1581 | 0.2132 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0019 | 0.028 | 0.0113 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.004 | 0.1581 | 0.2132 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0021 | 0.042 | 0.0254 |
Brugia malayi | hypothetical protein | 0.0021 | 0.042 | 0.0566 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.004 | 0.1581 | 0.1436 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.004 | 0.1581 | 0.1436 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0764 | 0.103 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.5447 | 0.5369 |
Brugia malayi | glutathione reductase | 0.0055 | 0.2511 | 0.3385 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0019 | 0.028 | 0.0378 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.1507 | 0.136 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 1 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0326 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.1507 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.004 | 0.1581 | 0.1436 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.1507 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0126 | 0.6856 | 0.8837 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.017 | 0.0229 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0019 | 0.028 | 0.0113 |
Leishmania major | trypanothione reductase | 0.0055 | 0.2511 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.004 | 0.1581 | 0.2132 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0019 | 0.028 | 0.0378 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0326 | 0.0145 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.004 | 0.1581 | 0.2132 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.004 | 0.1581 | 0.1436 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1581 | 0.2132 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0019 | 0.028 | 0.0378 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.042 | 0.0566 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0798 | 0.2272 |
Brugia malayi | nuclear receptor RXR | 0.0019 | 0.028 | 0.0378 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0103 | 0.5447 | 0.5369 |
Brugia malayi | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Loa Loa (eye worm) | glutathione reductase | 0.0055 | 0.2511 | 0.3385 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0019 | 0.028 | 0.0113 |
Brugia malayi | nuclear receptor RXR | 0.0021 | 0.042 | 0.0566 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0126 | 0.6856 | 0.8837 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0798 | 0.1076 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0019 | 0.028 | 0.0113 |
Mycobacterium tuberculosis | Probable reductase | 0.0126 | 0.6856 | 0.8837 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.004 | 0.1581 | 0.2132 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0326 | 0.0145 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0019 | 0.028 | 0.0378 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0055 | 0.2511 | 0.3385 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.004 | 0.1581 | 0.1436 |
Echinococcus granulosus | FTZ F1 alpha | 0.004 | 0.1581 | 0.1436 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0326 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1581 | 0.2132 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.1507 | 0.136 |
Brugia malayi | ecdysteroid receptor | 0.004 | 0.1581 | 0.2132 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.1507 | 1 |
Brugia malayi | ecdysone receptor | 0.0019 | 0.028 | 0.0378 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0019 | 0.0294 | 0.0127 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.7417 | 0.7372 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0326 | 0.0145 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.004 | 0.1581 | 0.1436 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0019 | 0.028 | 0.0113 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.004 | 0.1581 | 0.1436 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0203 | 0.0273 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0764 | 0.0604 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0326 | 0.0145 |
Loa Loa (eye worm) | RNA binding protein | 0.0135 | 0.7417 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.004 | 0.1581 | 0.1436 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.004 | 0.1581 | 0.2132 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.7417 | 0.7372 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.042 | 0.0254 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.1507 | 0.136 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.004 | 0.1581 | 0.1436 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.004 | 0.1581 | 0.2132 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0326 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0326 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.7417 | 0.7372 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.014 | 0.772 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0764 | 0.0604 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0126 | 0.6856 | 0.8837 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.1507 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0103 | 0.5447 | 0.5369 |
Schistosoma mansoni | coup transcription factor | 0.004 | 0.1581 | 0.1436 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0019 | 0.028 | 0.0113 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0798 | 0.2272 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0019 | 0.0294 | 0.0127 |
Brugia malayi | nuclear hormone receptor | 0.004 | 0.1581 | 0.2132 |
Loa Loa (eye worm) | DR-78 | 0.0019 | 0.028 | 0.0378 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.004 | 0.1581 | 0.1436 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Plasmodium vivax | glutathione reductase, putative | 0.0055 | 0.2511 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0126 | 0.6856 | 0.8837 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0019 | 0.028 | 0.0113 |
Brugia malayi | RNA binding protein | 0.0135 | 0.7417 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0135 | 0.7417 | 0.7372 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.7417 | 0.7372 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.004 | 0.1581 | 0.1436 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.004 | 0.1581 | 0.2132 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.004 | 0.1581 | 0.1436 |
Brugia malayi | nuclear hormone receptor | 0.0019 | 0.028 | 0.0378 |
Brugia malayi | MH2 domain containing protein | 0.0125 | 0.6834 | 0.9214 |
Onchocerca volvulus | 0.004 | 0.1581 | 1 | |
Echinococcus multilocularis | geminin | 0.0177 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0135 | 0.7417 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0055 | 0.2511 | 0.2382 |
Brugia malayi | Thioredoxin reductase | 0.0055 | 0.2511 | 0.3385 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.004 | 0.1581 | 0.1436 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.014 | 0.772 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0019 | 0.028 | 0.0378 |
Echinococcus granulosus | tar DNA binding protein | 0.0135 | 0.7417 | 0.7372 |
Schistosoma mansoni | nuclear hormone receptor | 0.0019 | 0.028 | 0.0113 |
Brugia malayi | tailless protein | 0.0019 | 0.028 | 0.0378 |
Brugia malayi | nuclear receptor NHR-88 | 0.0019 | 0.028 | 0.0378 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0764 | 0.0604 |
Toxoplasma gondii | thioredoxin reductase | 0.0055 | 0.2511 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0798 | 0.2272 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1581 | 0.2132 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0019 | 0.028 | 0.0378 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.004 | 0.1581 | 0.1436 |
Echinococcus multilocularis | FTZ F1 alpha | 0.004 | 0.1581 | 0.1436 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0055 | 0.2511 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.004 | 0.1581 | 0.2132 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0125 | 0.6834 | 0.9214 |
Plasmodium falciparum | thioredoxin reductase | 0.0055 | 0.2511 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0019 | 0.0294 | 0.0397 |
Schistosoma mansoni | thyroid hormone receptor | 0.004 | 0.1581 | 0.1436 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0326 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0019 | 0.028 | 0.0378 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.1389 | 0.124 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.004 | 0.1581 | 0.2132 |
Brugia malayi | hypothetical protein | 0.0021 | 0.042 | 0.0566 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1389 | 0.1873 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0798 | 0.1076 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.028 | 0.0113 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0055 | 0.2511 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.004 | 0.1581 | 1 |
Schistosoma mansoni | lamin | 0.0027 | 0.0764 | 0.0604 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0326 | 0.016 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.5447 | 0.5369 |
Brugia malayi | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.244 | 0.3289 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0021 | 0.042 | 0.0566 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.7417 | 0.7372 |
Schistosoma mansoni | nuclear hormone receptor | 0.004 | 0.1581 | 0.1436 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0798 | 0.2272 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.004 | 0.1581 | 0.2132 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.004 | 0.1581 | 0.1436 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.004 | 0.1581 | 0.2132 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.004 | 0.1581 | 0.2132 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1581 | 0.2132 |
Loa Loa (eye worm) | TAR-binding protein | 0.0135 | 0.7417 | 1 |
Onchocerca volvulus | 0.0027 | 0.0764 | 0.3717 | |
Brugia malayi | RNA recognition motif domain containing protein | 0.0135 | 0.7417 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.017 | 0.0229 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.004 | 0.1581 | 0.1436 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1581 | 0.2132 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.042 | 0.0566 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.004 | 0.1581 | 0.1436 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0055 | 0.2511 | 0.2985 |
Loa Loa (eye worm) | steroid hormone receptor | 0.004 | 0.1581 | 0.2132 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.004 | 0.1581 | 0.2132 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.004 | 0.1581 | 0.1436 |
Schistosoma mansoni | thyroid hormone receptor | 0.004 | 0.1581 | 0.1436 |
Brugia malayi | nuclear receptor NHR-88 | 0.004 | 0.1581 | 0.2132 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0019 | 0.028 | 0.0113 |
Trypanosoma brucei | trypanothione reductase | 0.0055 | 0.2511 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0326 | 0.016 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.042 | 0.0566 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.042 | 0.0566 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0326 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0764 | 0.103 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.5447 | 0.5369 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.004 | 0.1581 | 0.1436 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0764 | 0.103 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.004 | 0.1581 | 0.2132 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0103 | 0.5447 | 0.5369 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.1507 | 0.136 |
Onchocerca volvulus | 0.0027 | 0.0764 | 0.3717 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0378 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 1.86 | Inhibition of CHK1 (unknown origin) assessed as inhibition of CDC25 phosphorylation after 30 min by DELFIA assay | ChEMBL. | No reference |
IC50 (binding) | = 72 uM | Inhibition of CHK1 by DELFIA | ChEMBL. | 20561787 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.