Detailed information for compound 113712

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 368.36 | Formula: C18H21N2NaO5
  • H donors: 1 H acceptors: 5 LogP: 2.76 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@@H]([C@H]1C(=O)N2[C@@H]1OC(=C2C(=O)[O-])C(C)(C)C)CCc1ccncc1.[Na+]
  • InChi: 1S/C18H22N2O5.Na/c1-18(2,3)14-13(17(23)24)20-15(22)12(16(20)25-14)11(21)5-4-10-6-8-19-9-7-10;/h6-9,11-12,16,21H,4-5H2,1-3H3,(H,23,24);/q;+1/p-1/t11-,12+,16-;/m1./s1
  • InChiKey: PDXKWYXOEVMXCT-FLHZUECGSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis tar DNA binding protein 0.0061 0.004 0.005
Onchocerca volvulus 0.0023 0.0003 0.0036
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Echinococcus granulosus Coagulation factor 5 8 type C terminal 0.0044 0.0023 0.0023
Onchocerca volvulus 0.0029 0.0009 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0009 0.0009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.6322 0.6105 1
Loa Loa (eye worm) DEAH box polypeptide 35 0.0033 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Echinococcus granulosus protein arginine N methyltransferase 7 0.0053 0.0032 0.0032
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0025 0.0004 0.0001
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0044 0.0023 0.0038
Brugia malayi Disintegrin family protein 0.0037 0.0016 0.0016
Entamoeba histolytica hypothetical protein 0.0147 0.0123 0.1789
Mycobacterium ulcerans NAD-dependent deacetylase 0.0108 0.0085 0.194
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0029 0.0009 0.0009
Plasmodium falciparum plasmepsin III 0.0038 0.0017 0.0408
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0009 0.0009
Schistosoma mansoni microtubule-associated protein tau 0.0673 0.0632 0.0632
Echinococcus multilocularis serine:threonine protein kinase N2 0.0087 0.0065 0.0081
Mycobacterium leprae conserved hypothetical protein 0.0113 0.009 0.2036
Brugia malayi G-protein coupled receptor 0.0029 0.0009 0.0009
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0029 0.0009 0.0009
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0108 0.0085 0.0225
Echinococcus multilocularis NMDA receptor 0.0031 0.001 0.0013
Echinococcus multilocularis integrin alpha ps 0.0097 0.0074 0.0093
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0455 0.0421 1
Brugia malayi TAR-binding protein 0.0061 0.004 0.004
Schistosoma mansoni biogenic amine receptor 0.0029 0.0009 0.0009
Echinococcus multilocularis somatostatin receptor 0.0029 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Brugia malayi hypothetical protein 0.0029 0.0009 0.0009
Onchocerca volvulus 0.0029 0.0009 0.0123
Leishmania major silent information regulator 2, putative 0.0732 0.069 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Schistosoma mansoni chromatin regulatory protein sir2 0.0732 0.069 0.069
Toxoplasma gondii subtilisin SUB10 0.0455 0.0421 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.009 0.009
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.067 0.0629 0.0629
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.2059 0.1975 0.3235
Onchocerca volvulus 0.0029 0.0009 0.0123
Onchocerca volvulus 0.0038 0.0017 0.024
Brugia malayi serpin (BmSERPIN) 0.0023 0.0003 0.0003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Brugia malayi Furin-like cysteine rich region family protein 0.0648 0.0608 0.0608
Schistosoma mansoni integrin alpha 0.0449 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0025 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0014
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0029 0.0009 0.0009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.6322 0.6105 1
Brugia malayi serpin 0.0023 0.0003 0.0003
Loa Loa (eye worm) DPY-31 protein 0.0026 0.0006 0.0006
Echinococcus multilocularis microtubule associated protein 2 0.0673 0.0632 0.079
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0113 0.009 0.1268
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.009 0.009
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0455 0.0421 1
Brugia malayi Eukaryotic aspartyl protease family protein 0.0038 0.0017 0.0017
Brugia malayi Calcium binding EGF domain containing protein 0.0035 0.0014 0.0014
Onchocerca volvulus 0.0035 0.0014 0.0197
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Echinococcus granulosus methyltransferase protein 5 0.0053 0.0032 0.0032
Echinococcus multilocularis disintegrin and metalloproteinase 0.0037 0.0016 0.002
Schistosoma mansoni adenoreceptor 0.0029 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0455 0.0421 0.069
Giardia lamblia hypothetical protein 0.0059 0.0038 0.0096
Echinococcus granulosus integrin alpha 3 0.0345 0.0314 0.0314
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0009 0.0011
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0116 0.0093 0.0093
Schistosoma mansoni dock 0.0044 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0147 0.0123 0.0123
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0029 0.0009 0.0011
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0009 0.0009
Echinococcus granulosus Estrogen regulated protein EP45 0.0023 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Brugia malayi CUB domain containing protein 0.0026 0.0006 0.0006
Plasmodium vivax plasmepsin IV, putative 0.0038 0.0017 0.0408
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0031 0.001 0.0013
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0732 0.069 0.0862
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2514 0.2416 0.3957
Brugia malayi CUB domain containing protein 0.0026 0.0006 0.0006
Brugia malayi hypothetical protein 0.0029 0.0009 0.0009
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0108 0.0085 0.0106
Brugia malayi putative neuropeptide receptor 0.0029 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0199 0.0174 0.0174
Schistosoma mansoni hypothetical protein 0.0035 0.0015 0.0015
Schistosoma mansoni biogenic amine receptor 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.402 0.3875 0.3875
Echinococcus granulosus c-Jun N-terminal kinases 0.023 0.0203 0.0203
Schistosoma mansoni hypothetical protein 0.0026 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Plasmodium vivax aspartyl protease, putative 0.0038 0.0017 0.0408
Trichomonas vaginalis conserved hypothetical protein 0.0455 0.0421 0.069
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0094 0.0072 0.1708
Loa Loa (eye worm) TK/EGFR protein kinase 0.0648 0.0608 0.0608
Onchocerca volvulus 0.0029 0.0009 0.0123
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Echinococcus granulosus g protein coupled receptor 0.0029 0.0009 0.0009
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0053 0.0032 0.0032
Echinococcus granulosus neuropeptide receptor 0.0029 0.0009 0.0009
Echinococcus granulosus c4b binding protein beta chain 0.0035 0.0014 0.0014
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1432 0.1368 0.1368
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0023 0.0547
Onchocerca volvulus 0.0026 0.0006 0.008
Loa Loa (eye worm) hypothetical protein 0.0079 0.0057 0.0057
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0053 0.0032 0.0403
Trichomonas vaginalis conserved hypothetical protein 0.2059 0.1975 0.3235
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0074 0.0053 0.0719
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0017 0.0017
Brugia malayi G protein-coupled receptor F59B2.13 0.0029 0.0009 0.0009
Leishmania major arginine N-methyltransferase-like protein 0.0094 0.0072 0.0986
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0732 0.069 1
Trypanosoma brucei SIR2-like protein 4, putative 0.0108 0.0085 0.1179
Toxoplasma gondii subtilisin SUB5 0.0455 0.0421 1
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0026 0.0006 0.0006
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0025 0.0032
Plasmodium vivax aspartyl proteinase, putative 0.0038 0.0017 0.0408
Echinococcus multilocularis dro:myosuppressin receptor 0.0029 0.0009 0.0011
Loa Loa (eye worm) glutamate receptor 1 0.0031 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0026 0.0006 0.0006
Brugia malayi Carm1-pending protein 0.0053 0.0032 0.0032
Echinococcus multilocularis 0.8284 0.8006 1
Echinococcus granulosus fibrillin 1 0.0081 0.006 0.006
Loa Loa (eye worm) hypothetical protein 1.0343 1 1
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0108 0.0085 0.2023
Mycobacterium tuberculosis Probable hydrolase 0.0113 0.009 0.1268
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0082 0.006 0.0826
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.0042 0.0042
Echinococcus granulosus sex peptide receptor 0.0029 0.0009 0.0009
Brugia malayi transcriptional regulator, Sir2 family protein 0.0732 0.069 0.069
Plasmodium falciparum subtilisin-like protease 3 0.0455 0.0421 1
Giardia lamblia Hypothetical protein 0.0732 0.069 0.1874
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0009 0.0009
Schistosoma mansoni protein kinase 0.0127 0.0103 0.0103
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2514 0.2416 0.3957
Schistosoma mansoni hypothetical protein 0.0053 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0023
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.0085 0.014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0009 0.0011
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0114 0.0142
Giardia lamblia Sirtuin type 2 0.0108 0.0085 0.0225
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Toxoplasma gondii rhoptry neck protein RON1 0.0035 0.0014 0.0334
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0009 0.0009
Brugia malayi RNA binding protein 0.0061 0.004 0.004
Toxoplasma gondii SWIRM domain-containing protein 0.0059 0.0038 0.09
Loa Loa (eye worm) hypothetical protein 0.0038 0.0017 0.0017
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0038 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0038 0.0062
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.0042 0.0042
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.004 0.004
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0029 0.0009 0.0009
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Brugia malayi serpin 0.0023 0.0003 0.0003
Brugia malayi Tachykinin-like peptides receptor 99D 0.0029 0.0009 0.0009
Onchocerca volvulus 0.0029 0.0009 0.0123
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0029 0.0009 0.0009
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0025 0.0583
Brugia malayi BmSERPIN 0.0023 0.0003 0.0003
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0732 0.069 0.069
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.0085 0.014
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0053 0.0032 0.004
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0009 0.0009
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0053 0.0032 0.004
Loa Loa (eye worm) CUB domain-containing protein 0.0026 0.0006 0.0006
Schistosoma mansoni neuropeptide f receptor 76f 0.0029 0.0009 0.0009
Echinococcus multilocularis epidermal growth factor receptor 0.0648 0.0608 0.076
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0622 0.0584 0.0584
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0094 0.0072 0.0072
Schistosoma mansoni neuropeptide receptor 0.0029 0.0009 0.0009
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0036 0.0847
Echinococcus multilocularis glutamate receptor 2 0.0046 0.0025 0.0032
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0029 0.0009 0.0009
Echinococcus multilocularis protein kinase c epsilon type 0.0095 0.0072 0.009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Brugia malayi hypothetical protein 0.0147 0.0123 0.0123
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.6322 0.6105 0.7626
Echinococcus multilocularis GPCR, family 2 0.0063 0.0042 0.0052
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0009 0.0009
Chlamydia trachomatis protoporphyrinogen oxidase 0.0142 0.0118 1
Onchocerca volvulus 0.0023 0.0003 0.0036
Schistosoma mansoni discoidin domain receptor 0.0044 0.0023 0.0023
Echinococcus granulosus furin 1.0343 1 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0025 0.0025
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0077 0.0055 0.1207
Onchocerca volvulus 0.0029 0.0009 0.0123
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0009 0.0009
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0029 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Echinococcus granulosus somatostatin receptor 0.0029 0.0009 0.0009
Toxoplasma gondii subtilisin SUB12 0.0455 0.0421 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0009 0.0009
Plasmodium vivax histone acetyltransferase GCN5, putative 0.005 0.0029 0.0678
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.009 0.0147
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0017 0.0017
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0077 0.0055 0.0055
Brugia malayi Kringle domain containing protein 0.0031 0.0011 0.0011
Echinococcus granulosus g-protein coupled receptor 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0142 0.0118 0.0118
Brugia malayi hypothetical protein 0.0035 0.0014 0.0014
Brugia malayi EGF-like domain containing protein 0.0079 0.0057 0.0057
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.0042 0.0042
Trichomonas vaginalis hypothetical protein 0.2059 0.1975 0.3235
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0026 0.0006 0.0006
Echinococcus multilocularis chromatin regulatory protein sir2 0.0732 0.069 0.0862
Entamoeba histolytica hypothetical protein 0.0035 0.0015 0.0211
Echinococcus granulosus chromatin regulatory protein sir2 0.0732 0.069 0.069
Echinococcus granulosus adam 0.0195 0.017 0.017
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0142 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0014
Leishmania major UDP-galactopyranose mutase 0.0142 0.0118 0.1662
Brugia malayi hypothetical protein 0.0029 0.0009 0.0009
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0108 0.0085 0.1179
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0029 0.0009 0.0009
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0455 0.0421 1
Schistosoma mansoni amine GPCR 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.2059 0.1975 0.3235
Onchocerca volvulus 0.0175 0.015 0.2098
Echinococcus multilocularis integrin alpha 3 0.0345 0.0314 0.0393
Onchocerca volvulus 0.0023 0.0003 0.0036
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0074 0.0053 0.0053
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0113 0.009 0.009
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0029 0.0009 0.0009
Echinococcus granulosus discoidin domain containing receptor 2 0.0044 0.0023 0.0023
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0029 0.0009 0.0009
Giardia lamblia High cysteine membrane protein Group 2 0.3809 0.367 1
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0699 0.0658 0.0822
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0455 0.0421 0.0526
Brugia malayi Subtilase family protein 0.0455 0.0421 0.0421
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0053 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Echinococcus granulosus serine:threonine protein kinase N2 0.0077 0.0056 0.0056
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0147 0.0123 0.1737
Echinococcus multilocularis serotonin receptor 0.0029 0.0009 0.0011
Echinococcus multilocularis CUB 0.0026 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0009 0.0009
Brugia malayi beta-lactamase family protein 0.0113 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0108 0.0085 0.0085
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0037 0.0016 0.002
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 1.0343 1 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0077 0.0055 0.0755
Loa Loa (eye worm) CUB domain-containing protein 0.0026 0.0006 0.0006
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0035 0.0014 0.0014
Brugia malayi protein kinase C II. 0.0095 0.0072 0.0072
Trichomonas vaginalis hypothetical protein 0.0044 0.0023 0.0038
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0108 0.0085 0.1179
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0025 0.0025
Schistosoma mansoni serine protease inhibitors serpins 0.0023 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0035 0.0015 0.0211
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Mycobacterium tuberculosis Conserved hypothetical protein 0.0142 0.0118 0.1693
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0061 0.004 0.0856
Loa Loa (eye worm) proprotein convertase 2 0.2514 0.2416 0.2416
Brugia malayi GCC2 and GCC3 family protein 0.0044 0.0023 0.0023
Onchocerca volvulus 0.0035 0.0014 0.0197
Loa Loa (eye worm) serpin 0.0023 0.0003 0.0003
Echinococcus granulosus cubilin 0.0026 0.0006 0.0006
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0009 0.0011
Onchocerca volvulus 0.0072 0.0051 0.071
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Echinococcus granulosus fibrillin 2 0.0079 0.0057 0.0057
Schistosoma mansoni site-1 peptidase (S08 family) 0.0455 0.0421 0.0421
Echinococcus multilocularis discoidin domain containing receptor 2 0.0044 0.0023 0.0029
Leishmania major arginine N-methyltransferase, type I 0.0053 0.0032 0.0403
Brugia malayi Lectin C-type domain containing protein 0.0026 0.0006 0.0006
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0138 0.0114 0.0114
Mycobacterium tuberculosis Possible oxidoreductase 0.0142 0.0118 0.1693
Loa Loa (eye worm) zinc metalloproteinase toh-2 0.0026 0.0006 0.0006
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0077 0.0055 0.076
Schistosoma mansoni hypothetical protein 0.0026 0.0006 0.0006
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0258 0.0231 0.0289
Trichomonas vaginalis esterase, putative 0.0113 0.009 0.0147
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0094 0.0072 0.0072
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0113 0.009 0.1268
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0053 0.0032 0.0032
Schistosoma mansoni btb and poz domain-containing protein 0.0044 0.0023 0.0023
Onchocerca volvulus 0.0029 0.0009 0.0123
Echinococcus granulosus protein arginine methyltransferase 0.0094 0.0072 0.0072
Brugia malayi hypothetical protein 0.0038 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0113 0.009 0.2046
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0053 0.0032 0.0403
Schistosoma mansoni hypothetical protein 0.0397 0.0365 0.0365
Echinococcus multilocularis protoporphyrinogen oxidase 0.0142 0.0118 0.0148
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0481 0.0446 0.6449
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Schistosoma mansoni glutamate receptor kainate 0.0031 0.001 0.001
Plasmodium falciparum plasmepsin X 0.0038 0.0017 0.0408
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0094 0.0072 0.0118
Onchocerca volvulus 0.0023 0.0003 0.0036
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0455 0.0421 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0032 0.0032
Brugia malayi Sex muscle abnormal protein 5 0.0126 0.0103 0.0103
Echinococcus granulosus SWI:SNF complex subunit SMARCC2 0.0059 0.0038 0.0038
Schistosoma mansoni glutamate receptor AMPA 0.0031 0.001 0.001
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0026 0.0006 0.0006
Onchocerca volvulus 0.0026 0.0006 0.008
Echinococcus multilocularis Furin 1 0.2514 0.2416 0.3017
Schistosoma mansoni glutamate receptor AMPA 0.0031 0.001 0.001
Echinococcus multilocularis C type lectin domian containing protein 0.0035 0.0014 0.0018
Brugia malayi Zinc metalloproteinase toh-2 precursor 0.0026 0.0006 0.0006
Mycobacterium leprae Probable lipase LipE 0.0113 0.009 0.2036
Loa Loa (eye worm) aspartyl protease 6 0.0038 0.0017 0.0017
Toxoplasma gondii PA14 domain-containing protein 0.0044 0.0023 0.0547
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Mycobacterium ulcerans fatty acid synthase Fas 0.0025 0.0005 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0009 0.0009
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.0025 0.0356
Echinococcus granulosus protein arginine N methyltransferase 8 0.0094 0.0072 0.0072
Onchocerca volvulus 0.0029 0.0009 0.0123
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.0085 0.014
Echinococcus granulosus neuropeptide receptor 0.0029 0.0009 0.0009
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.067 0.0629 0.0786
Echinococcus multilocularis growth factor receptor bound protein 2 0.0126 0.0103 0.0129
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0142 0.0118 0.2807
Brugia malayi Serpin protein 6 0.0023 0.0003 0.0003
Echinococcus granulosus beta LACTamase domain containing family member 0.0113 0.009 0.009
Giardia lamblia Neurogenic locus notch-like protein 0.0079 0.0057 0.0149
Loa Loa (eye worm) hypothetical protein 0.0699 0.0658 0.0658
Schistosoma mansoni serine protease inhibitors serpins 0.0023 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Echinococcus multilocularis protein jagged 2 0.0079 0.0057 0.0071
Plasmodium vivax apical sushi protein, putative 0.0035 0.0014 0.0334
Toxoplasma gondii subtilisin SUB4 0.0455 0.0421 1
Onchocerca volvulus 0.0029 0.0009 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.2059 0.1975 0.3235
Onchocerca volvulus 0.0028 0.0008 0.0106
Onchocerca volvulus 0.0035 0.0014 0.0197
Plasmodium falciparum subtilisin-like protease 1 0.0455 0.0421 1
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0053 0.0032 0.0761
Onchocerca volvulus 0.0148 0.0124 0.1737
Toxoplasma gondii subtilisin SUB1 0.0455 0.0421 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Mycobacterium ulcerans dehydrogenase 0.0142 0.0118 0.2733
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Echinococcus granulosus CUB 0.0026 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Trypanosoma cruzi UDP-galactopyranose mutase 0.0142 0.0118 0.1662
Brugia malayi hypothetical protein 0.0035 0.0014 0.0014
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0089 0.0067 0.0067
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.023 0.0203 0.0203
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.009 0.0147
Echinococcus multilocularis protein arginine methyltransferase 0.0094 0.0072 0.009
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0053 0.0032 0.0052
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0079 0.0057 0.1256
Loa Loa (eye worm) hypothetical protein 0.0031 0.0011 0.0011
Brugia malayi follicle stimulating hormone receptor 0.0029 0.0009 0.0009
Echinococcus granulosus g protein coupled receptor 0.0029 0.0009 0.0009
Echinococcus granulosus neuropeptide s receptor 0.0029 0.0009 0.0009
Toxoplasma gondii histone deacetylase SIR2-like 0.0108 0.0085 0.2023
Mycobacterium tuberculosis Possible arabinofuranosyltransferase AftD 0.0044 0.0023 0.0278
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0009 0.0009
Brugia malayi hypothetical protein 0.0029 0.0009 0.0009
Onchocerca volvulus 0.0029 0.0009 0.0123
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0038 0.0017 0.0408
Echinococcus multilocularis Estrogen regulated protein EP45 0.0023 0.0003 0.0003
Onchocerca volvulus 0.0031 0.0011 0.0148
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0142 0.0118 0.2724
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2514 0.2416 0.3957
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0015 0.0015
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0732 0.069 1
Brugia malayi EGF-like domain containing protein 0.0079 0.0057 0.0057
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0009 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0009 0.0011
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0053 0.0032 0.0403
Mycobacterium ulcerans polyketide synthase 0.0082 0.006 0.1333
Toxoplasma gondii aspartyl protease 0.0038 0.0017 0.0408
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Schistosoma mansoni amine oxidase 0.0142 0.0118 0.0118
Echinococcus granulosus C type lectin domian containing protein 0.0035 0.0014 0.0014
Onchocerca volvulus 0.0074 0.0053 0.0737
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0732 0.069 0.113
Leishmania major sir2-family protein-like protein 0.0108 0.0085 0.1179
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0029 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0009 0.0009
Brugia malayi Protein kinase domain containing protein 0.0044 0.0023 0.0023
Echinococcus granulosus hypothetical protein 0.0029 0.0009 0.0009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Toxoplasma gondii serpin (serine proteinase inhibitor) superfamily protein 0.0023 0.0003 0.0062
Plasmodium falciparum cysteine repeat modular protein 1 0.0031 0.0011 0.0251
Mycobacterium leprae Probable polyketide synthase Pks1 0.0082 0.006 0.1322
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0113 0.009 0.009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0009 0.0009
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0061 0.004 0.0845
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0014
Onchocerca volvulus 0.0139 0.0115 0.1607
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0732 0.069 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0079 0.0057 1
Echinococcus granulosus allatostatin A receptor 0.0029 0.0009 0.0009
Mycobacterium ulcerans Sir2-like regulatory protein 0.0108 0.0085 0.194
Toxoplasma gondii type I fatty acid synthase, putative 0.0057 0.0036 0.0844
Echinococcus granulosus cubilin 0.0026 0.0006 0.0006
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0009 0.0009
Echinococcus granulosus g protein coupled receptor 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Onchocerca volvulus 0.0029 0.0009 0.0123
Toxoplasma gondii F5/8 type C domain-containing protein 0.0044 0.0023 0.0547
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Brugia malayi Dopamine receptor protein 1 0.0029 0.0009 0.0009
Echinococcus granulosus tar DNA binding protein 0.0061 0.004 0.004
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0031 0.001 0.001
Onchocerca volvulus 0.0113 0.009 0.1253
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0053 0.0032 0.004
Echinococcus multilocularis neuroendocrine convertase 2 0.6534 0.631 0.7882
Schistosoma mansoni protein arginine n-methyltransferase 0.0053 0.0032 0.0032
Onchocerca volvulus 0.0023 0.0003 0.0036
Echinococcus granulosus tachykinin peptides receptor 99D 0.0029 0.0009 0.0009
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0108 0.0085 0.0085
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0111 0.0088 0.0088
Loa Loa (eye worm) WD40 repeat protein 0.0148 0.0124 0.0124
Toxoplasma gondii aspartyl protease ASP5 0.0387 0.0356 0.8441
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0037 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0455 0.0421 0.069
Schistosoma mansoni hypothetical protein 0.0044 0.0023 0.0023
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.0085 0.014
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Mycobacterium tuberculosis Probable esterase LipL 0.0113 0.009 0.1268
Brugia malayi serpin 0.0023 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Schistosoma mansoni serpin 0.0023 0.0003 0.0003
Echinococcus granulosus alpha 1A adrenergic receptor 0.0029 0.0009 0.0009
Brugia malayi Protein arginine N-methyltransferase 0.0053 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0063 0.0042 0.0042
Giardia lamblia High cysteine protein 0.0079 0.0057 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0455 0.0421 0.069
Brugia malayi ORL1-like opioid receptor 0.0029 0.0009 0.0009
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0147 0.0123 0.1737
Mycobacterium tuberculosis Conserved protein 0.0113 0.009 0.1268
Brugia malayi Nematode astacin protease protein 30 0.0026 0.0006 0.0006
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0131 0.0108 0.0108
Schistosoma mansoni integrin beta subunit 0.1854 0.1777 0.1777
Schistosoma mansoni chromatin regulatory protein sir2 0.0732 0.069 0.069
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Echinococcus multilocularis glutamate receptor 2 0.0031 0.001 0.0013
Loa Loa (eye worm) endoprotease bli-4 1.0343 1 1
Echinococcus multilocularis integrin alpha ps 0.0201 0.0176 0.022
Giardia lamblia Furin precursor putative serine protease 0.2059 0.1975 0.5378
Brugia malayi Glutamate receptor 2 precursor 0.0031 0.001 0.001
Giardia lamblia Tenascin-X 0.0079 0.0057 0.0149
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0004 0.0104
Echinococcus granulosus peptide allatostatin:somatostatin 0.0029 0.0009 0.0009
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0094 0.0072 0.009
Schistosoma mansoni tar DNA-binding protein 0.0061 0.004 0.004
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.005 0.0029 0.0579
Schistosoma mansoni hypothetical protein 0.0097 0.0074 0.0074
Brugia malayi Will die slowly protein 0.0148 0.0124 0.0124
Echinococcus granulosus nmda type glutamate receptor 0.0109 0.0086 0.0086
Plasmodium vivax hypothetical protein, conserved 0.0113 0.009 0.2128
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0014
Echinococcus multilocularis neuropeptide receptor A26 0.0029 0.0009 0.0011
Trichomonas vaginalis hypothetical protein 0.0079 0.0057 0.0094
Giardia lamblia Transcriptional regulator, Sir2 family 0.0108 0.0085 0.0225
Echinococcus multilocularis sex peptide receptor 0.0029 0.0009 0.0011
Brugia malayi CUB domain containing protein 0.0026 0.0006 0.0006
Giardia lamblia Tenascin precursor 0.0079 0.0057 0.0149
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0014
Echinococcus granulosus integrin alpha ps 0.0097 0.0074 0.0074
Giardia lamblia hypothetical protein 0.0079 0.0057 0.0149
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0052 0.0031 0.0728
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0038 0.0017 0.0021
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.6322 0.6105 0.6105
Echinococcus granulosus serine protease inhibitor 0.0023 0.0003 0.0003
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0094 0.0072 0.0118
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0732 0.069 1
Echinococcus granulosus Estrogen regulated protein EP45 0.0023 0.0003 0.0003
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0147 0.0123 0.1737
Schistosoma mansoni SWI/SNF complex-related 0.0059 0.0038 0.0038
Brugia malayi hypothetical protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) TAR-binding protein 0.0061 0.004 0.004
Entamoeba histolytica hypothetical protein 0.0035 0.0015 0.0211
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Brugia malayi neuroendocrine convertase 1 precursor 0.6534 0.631 0.631
Echinococcus granulosus serine protease inhibitor 0.0023 0.0003 0.0003
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.009 0.0147
Brugia malayi SWIRM domain containing protein 0.0059 0.0038 0.0038
Mycobacterium ulcerans polyketide synthase Pks9 0.005 0.0029 0.0591
Brugia malayi aspartic protease BmAsp-1, identical 0.0038 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0031 0.0011 0.0011
Brugia malayi serpin precursor 0.0023 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0072 0.0051 0.0051
Schistosoma mansoni growth factor receptor-bound protein 0.0126 0.0103 0.0103
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0009 0.0009
Echinococcus granulosus G protein coupled receptor 139 0.0029 0.0009 0.0009
Onchocerca volvulus 0.0029 0.0009 0.0123
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0077 0.0055 0.076
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0053 0.0032 0.0761
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0038 0.0017 0.0408
Loa Loa (eye worm) hypothetical protein 0.0455 0.0421 0.0421
Loa Loa (eye worm) glutamate receptor 2 0.0031 0.001 0.001
Schistosoma mansoni chromatin regulatory protein sir2 0.0732 0.069 0.069
Schistosoma mansoni c4b-binding protein beta chain 0.0035 0.0014 0.0014
Toxoplasma gondii histone deacetylase SIR2 0.0108 0.0085 0.2023
Onchocerca volvulus 0.0029 0.0009 0.0123
Onchocerca volvulus 0.0759 0.0715 1
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.026 0.0233 0.0233
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.005 0.0029 0.0047
Brugia malayi hypothetical protein 0.0038 0.0017 0.0017
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0029 0.0009 0.0009
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0455 0.0421 0.6195
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.009 0.1244
Brugia malayi Glutamate receptor 1 precursor 0.0031 0.001 0.001
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.0055 0.1218
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Loa Loa (eye worm) hypothetical protein 0.0079 0.0057 0.0057
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0732 0.069 0.113
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0142 0.0118 0.2807
Plasmodium falciparum protoporphyrinogen oxidase 0.0142 0.0118 0.2807
Echinococcus multilocularis adam 0.0195 0.017 0.0212
Loa Loa (eye worm) hypothetical protein 0.0113 0.009 0.009
Echinococcus granulosus adam 17 protease 0.0037 0.0016 0.0016
Brugia malayi hypothetical protein 0.0484 0.045 0.045
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0029 0.0009 0.0009
Mycobacterium leprae Possible secreted protease 0.0455 0.0421 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.0057 0.0057
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0108 0.0085 0.1179
Echinococcus granulosus glutamate receptor subunit protein glur 0.0031 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0063 0.0042 0.0042
Plasmodium falciparum plasmepsin V 0.0425 0.0392 0.931
Schistosoma mansoni neuropeptide receptor 0.0029 0.0009 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0009 0.0011
Loa Loa (eye worm) apoptosis regulator protein 0.0053 0.0032 0.0032
Brugia malayi hypothetical protein 0.0035 0.0014 0.0014
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0079 0.0057 0.0094
Schistosoma mansoni amine GPCR 0.0029 0.0009 0.0009
Brugia malayi zinc metalloproteinase toh-2 precursor 0.0026 0.0006 0.0006
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0144 0.012 0.2847
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0029 0.0009 0.0009
Toxoplasma gondii protease inhibitor PI1 0.0023 0.0003 0.0062
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.009 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Loa Loa (eye worm) TK/ROR protein kinase 0.0031 0.0011 0.0011
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0079 0.0057 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0051 0.0051
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.0085 0.0085
Plasmodium vivax plasmepsin V, putative 0.0425 0.0392 0.931
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0481 0.0446 0.6449
Echinococcus multilocularis c Jun NH2 terminal kinase 0.023 0.0203 0.0254
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0082 0.006 0.1333
Brugia malayi Protein kinase domain containing protein 0.0072 0.0051 0.0051
Loa Loa (eye worm) RNA binding protein 0.0061 0.004 0.004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0015 0.0018
Echinococcus granulosus neuropeptide FF receptor 2 0.0029 0.0009 0.0009
Loa Loa (eye worm) transcriptional regulator 0.0108 0.0085 0.0085
Brugia malayi Nematode astacin protease protein 30 0.0026 0.0006 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0009 0.0011
Brugia malayi hypothetical protein 0.0035 0.0014 0.0014
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0455 0.0421 0.0421
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0142 0.0118 0.2733
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0142 0.0118 0.2807
Plasmodium vivax hypothetical protein, conserved 0.0142 0.0118 0.2807
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.0055 0.1218
Trichomonas vaginalis conserved hypothetical protein 0.2059 0.1975 0.3235
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0053 0.0032 0.0465
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Echinococcus granulosus histone acetyltransferase KAT2B 0.0164 0.0139 0.0139
Toxoplasma gondii subtilisin SUB2 0.0455 0.0421 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0009 0.0009
Schistosoma mansoni serine protease inhibitors serpins 0.0023 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0017 0.0017
Brugia malayi Suppressor of lurcher protein 1 precursor 0.0026 0.0006 0.0006
Schistosoma mansoni integrin alpha-ps 0.0105 0.0082 0.0082
Schistosoma mansoni serpin 0.0023 0.0003 0.0003
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0038 0.0017 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.2059 0.1975 0.3235
Echinococcus granulosus epidermal growth factor receptor 0.0648 0.0608 0.0608
Mycobacterium ulcerans lipase LipD 0.0113 0.009 0.2046
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0082 0.006 0.1333
Brugia malayi hypothetical protein 0.0029 0.0009 0.0009
Brugia malayi hypothetical protein 0.0026 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Schistosoma mansoni biogenic amine receptor 0.0029 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0072 0.0051 0.0051
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0077 0.0055 0.1207
Loa Loa (eye worm) angiogenesis inhibito 0.0025 0.0004 0.0004
Toxoplasma gondii F5/8 type C domain-containing protein 0.0044 0.0023 0.0547
Toxoplasma gondii ABC1 family protein 0.0113 0.009 0.2128
Trypanosoma brucei subtilisin peptidase 0.0455 0.0421 0.6082
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0009 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0017 0.0017
Schistosoma mansoni neuropeptide receptor 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0042 0.0021 0.0021
Brugia malayi hypothetical protein 0.0035 0.0015 0.0015
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0026 0.0006 0.0006
Echinococcus granulosus GPCR family 2 0.0063 0.0042 0.0042
Toxoplasma gondii kringle domain-containing protein 0.0031 0.0011 0.0251
Brugia malayi neuropeptide F receptor 0.0029 0.0009 0.0009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Loa Loa (eye worm) TK/ALK protein kinase 0.0072 0.0051 0.0051
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.0085 0.0085
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0082 0.006 0.1322
Schistosoma mansoni hypothetical protein 0.0063 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0079 0.0057 0.0057
Brugia malayi celfurPC protein 0.8284 0.8006 0.8006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Schistosoma mansoni opsin-like receptor 0.0029 0.0009 0.0009
Mycobacterium ulcerans oxidoreductase 0.0142 0.0118 0.2733
Mycobacterium ulcerans thioesterase 0.0066 0.0045 0.0974
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0029 0.0009 0.0009
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.0042 0.0052
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0455 0.0421 1
Brugia malayi Latrophilin receptor protein 2 0.0063 0.0042 0.0042
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0108 0.0085 0.1179
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Echinococcus multilocularis fibrillin 1 0.0081 0.006 0.0074
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0053 0.0032 0.0403
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0009 0.0011
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0009 0.0011
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0009 0.0009
Echinococcus multilocularis neuropilin (nrp) and tolloid (tll) 0.0026 0.0006 0.0007
Brugia malayi Stress-activated protein kinase jnk-1 0.023 0.0203 0.0203
Brugia malayi NAD-dependent deacetylase SIRT1 0.0108 0.0085 0.0085
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0004 0.0104
Schistosoma mansoni dihydroceramide desaturase 0.0037 0.0016 0.0016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0009 0.0011
Echinococcus multilocularis discoidin domain receptor 0.0044 0.0023 0.0029
Loa Loa (eye worm) serpin 0.0023 0.0003 0.0003
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0089 0.0067 0.0083
Echinococcus granulosus lysine specific histone demethylase 1A 0.0142 0.0118 0.0118
Schistosoma mansoni opsin-like receptor 0.0029 0.0009 0.0009
Toxoplasma gondii subtilisin SUB6 0.0455 0.0421 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0113 0.009 0.1268
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0111 0.0088 0.0088
Entamoeba histolytica hypothetical protein 0.0035 0.0015 0.0211
Echinococcus granulosus lysine specific histone demethylase 1A 0.0699 0.0658 0.0658
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0114 0.0114
Echinococcus multilocularis beta LACTamase domain containing family member 0.0113 0.009 0.0112
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0031 0.001 0.0013
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2514 0.2416 0.3957
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0009 0.0009
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0699 0.0658 0.0658
Echinococcus multilocularis Estrogen regulated protein EP45 0.0023 0.0003 0.0003
Plasmodium falciparum plasmepsin I 0.0038 0.0017 0.0408
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0025 0.006
Brugia malayi beta-lactamase 0.0113 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Plasmodium vivax subtilisin-like serine protease, putative 0.0455 0.0421 1
Schistosoma mansoni tar DNA-binding protein 0.0061 0.004 0.004
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0025 0.0032
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0142 0.0118 0.2733
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0455 0.0421 0.6195
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0009 0.0011
Echinococcus multilocularis membrane bound transcription factor site 1 0.0455 0.0421 0.0526
Echinococcus granulosus microtubule associated protein 2 0.0673 0.0632 0.0632
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0029 0.0009 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0038 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0344 0.0314 0.0314
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0147 0.0123 0.1789
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Schistosoma mansoni amine GPCR 0.0029 0.0009 0.0009
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0127 0.0103 0.0103
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0046 0.0025 0.0032
Schistosoma mansoni protein kinase 0.0127 0.0103 0.0103
Onchocerca volvulus 0.0023 0.0003 0.0036
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0062 0.0041 0.0545
Echinococcus granulosus glutamate receptor 2 0.0046 0.0025 0.0025
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0045 0.0024 0.03
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Loa Loa (eye worm) hypothetical protein 0.0072 0.0051 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0004 0.0004
Onchocerca volvulus 0.0035 0.0014 0.0197
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0017 0.0017
Mycobacterium ulcerans thioesterase TesA 0.0066 0.0045 0.0974
Brugia malayi hypothetical protein 0.0072 0.0051 0.0051
Schistosoma mansoni tar DNA-binding protein 0.0061 0.004 0.004
Plasmodium falciparum plasmepsin VII 0.0038 0.0017 0.0408
Loa Loa (eye worm) hypothetical protein 0.0113 0.009 0.009
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.0055 0.1218
Brugia malayi astacin protease protein 30 0.0026 0.0006 0.0006
Echinococcus multilocularis tissue type plasminogen activator 0.0031 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0031
Echinococcus multilocularis protein will die slowly 0.0148 0.0124 0.0155
Schistosoma mansoni serine protease inhibitors serpins 0.0023 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0031 0.0011 0.0011
Giardia lamblia High cysteine protein 0.0079 0.0057 0.0149
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0004 0.0104
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.0085 0.0085
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Loa Loa (eye worm) hypothetical protein 0.0199 0.0174 0.0174
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0009 0.0011
Mycobacterium ulcerans monoamine oxidase 0.0142 0.0118 0.2733
Echinococcus granulosus integrin beta 2 0.2338 0.2246 0.2246
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0015 0.0015
Echinococcus granulosus disintegrin and metalloproteinase 0.0037 0.0016 0.0016
Plasmodium vivax NAD-dependent deacetylase, putative 0.0108 0.0085 0.2023
Brugia malayi hypothetical protein 0.0035 0.0014 0.0014
Brugia malayi aspartic protease BmAsp-2, identical 0.0038 0.0017 0.0017
Loa Loa (eye worm) reprolysin 0.0089 0.0067 0.0067
Onchocerca volvulus 0.0029 0.0009 0.0123
Loa Loa (eye worm) hypothetical protein 0.0089 0.0067 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Schistosoma mansoni hypothetical protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) beta-lactamase 0.0113 0.009 0.009
Brugia malayi hypothetical protein 0.0035 0.0014 0.0014
Brugia malayi ADAM-TS Spacer 1 family protein 0.0052 0.0031 0.0031
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0094 0.0072 0.0118
Brugia malayi serpin (BmSERPIN) 0.0023 0.0003 0.0003
Brugia malayi serpin 0.0023 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0455 0.0421 0.0421
Schistosoma mansoni ADAMTS14 peptidase (M12 family) 0.0025 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Brugia malayi CUB domain containing protein 0.0026 0.0006 0.0006
Brugia malayi sulfakinin receptor protein 0.0029 0.0009 0.0009
Trichomonas vaginalis WD repeat domain, putative 0.0148 0.0124 0.0204
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0077 0.0055 0.0755
Schistosoma mansoni neuropeptide receptor 0.0029 0.0009 0.0009
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0009 0.0011
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.005 0.0029 0.0678
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0009 0.0011
Leishmania major hypothetical protein, conserved 0.0113 0.009 0.1244
Schistosoma mansoni hypothetical protein 0.0053 0.0032 0.0032
Brugia malayi AKH receptor 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0014
Brugia malayi hypothetical protein 0.0023 0.0003 0.0003
Schistosoma mansoni serine protease inhibitors serpins 0.0023 0.0003 0.0003
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0108 0.0085 0.1235
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0108 0.0085 0.2023
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0073 0.0051 0.0051
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0116 0.0093 0.1322
Echinococcus multilocularis G-protein coupled receptor, putative 0.0029 0.0009 0.0011
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0079 0.0057 0.0778
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0455 0.0421 0.0421
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2514 0.2416 0.3957
Brugia malayi Integrin alpha pat-2 precursor 0.0449 0.0416 0.0416
Schistosoma mansoni septate junction protein 0.0053 0.0032 0.0032
Schistosoma mansoni alpha-1 adrenergic receptor 0.0029 0.0009 0.0009
Echinococcus granulosus tissue type plasminogen activator 0.0031 0.0011 0.0011
Echinococcus multilocularis neuropeptide FF receptor 2 0.0029 0.0009 0.0011
Schistosoma mansoni cpg binding protein 0.0029 0.0009 0.0009
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0108 0.0085 0.0085
Brugia malayi MH2 domain containing protein 0.0127 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Plasmodium vivax aspartyl protease, putative 0.0038 0.0017 0.0408
Echinococcus multilocularis nmda type glutamate receptor 0.0109 0.0086 0.0108
Mycobacterium ulcerans beta-lactamase 0.0113 0.009 0.2046
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Schistosoma mansoni growth hormone secretagogue receptor 0.0029 0.0009 0.0009
Entamoeba histolytica SWIRM domain protein 0.0059 0.0038 0.0549
Schistosoma mansoni hypothetical protein 0.0063 0.0042 0.0042
Echinococcus granulosus protein will die slowly 0.0148 0.0124 0.0124
Schistosoma mansoni glutamate receptor kainate 0.0031 0.001 0.001
Echinococcus granulosus fmrfamide receptor 0.0029 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0053 0.0032 0.0032
Echinococcus granulosus integrin alpha ps 0.0201 0.0176 0.0176
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.0085 0.0085
Brugia malayi BmSERPIN, truncated 0.0023 0.0003 0.0003
Plasmodium falciparum plasmepsin II 0.0038 0.0017 0.0408
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0009 0.0009
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.0085 0.014
Echinococcus multilocularis serine protease inhibitor 0.0023 0.0003 0.0003
Onchocerca volvulus Putative cubilin 0.0035 0.0014 0.0201
Schistosoma mansoni hypothetical protein 0.0029 0.0009 0.0009
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0031 0.0011 0.0251
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.0042 0.0042
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0009 0.0011
Toxoplasma gondii subtilisin SUB7 0.0455 0.0421 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0014
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0455 0.0421 0.0421
Schistosoma mansoni hypothetical protein 0.2059 0.1975 0.1975
Trichomonas vaginalis conserved hypothetical protein 0.2059 0.1975 0.3235
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.009 0.0147
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0077 0.0055 0.1218
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0168 0.0144 0.018
Mycobacterium ulcerans polyketide synthase 0.0077 0.0055 0.1218
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Schistosoma mansoni glutamate receptor kainate 0.0031 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0148 0.0124 0.0124
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.0365 0.0456
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0109 0.0086 0.0108
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0094 0.0072 0.1708
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0023
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0116 0.0093 0.1322
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0114 0.0142
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Loa Loa (eye worm) serpin 0.0023 0.0003 0.0003
Brugia malayi transcriptional regulator, Sir2 family protein 0.0108 0.0085 0.0085
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1803 0.1727 0.2157
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0719 0.0677 1
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0094 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0038 0.0062
Schistosoma mansoni cpg binding protein 0.0028 0.0008 0.0008
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0455 0.0421 0.6195
Mycobacterium ulcerans hypothetical protein 0.0113 0.009 0.2046
Brugia malayi transcriptional regulator, Sir2 family protein 0.0108 0.0085 0.0085
Schistosoma mansoni growth factor receptor-bound protein 0.0126 0.0103 0.0103
Onchocerca volvulus 0.0029 0.0009 0.0123
Echinococcus multilocularis 0.0142 0.0118 0.0148
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Brugia malayi Integrin beta pat-3 precursor 0.3165 0.3047 0.3047
Trypanosoma cruzi subtilisin peptidase 0.0455 0.0421 0.6082
Trichomonas vaginalis conserved hypothetical protein 0.2059 0.1975 0.3235
Schistosoma mansoni furin-1 (S08 family) 0.4475 0.4316 0.4316
Schistosoma mansoni cathepsin D (A01 family) 0.0038 0.0017 0.0017
Onchocerca volvulus 0.0026 0.0006 0.008
Echinococcus multilocularis serine protease inhibitor 0.0023 0.0003 0.0003
Brugia malayi Probable ATP-dependent helicase DHX35 0.0033 0.0013 0.0013
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Mycobacterium tuberculosis Conserved protein 0.0113 0.009 0.1268
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0019 0.0019
Loa Loa (eye worm) subtilase 0.0455 0.0421 0.0421
Giardia lamblia Tenascin-37 0.0079 0.0057 0.0149
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0042 0.0042
Echinococcus granulosus dnaJ subfamily B 0.0397 0.0365 0.0365
Toxoplasma gondii subtilisin SUB11 0.0455 0.0421 1
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0053 0.0032 0.0403
Onchocerca volvulus 0.0044 0.0023 0.0322
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0142 0.0118 0.2807
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0126 0.0103 0.0103
Echinococcus multilocularis g-protein coupled receptor 0.0029 0.0009 0.0011
Onchocerca volvulus 0.0035 0.0014 0.0197
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0127 0.0103 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.2059 0.1975 0.3235
Leishmania major subtilisin-like serine peptidase 0.0455 0.0421 0.6082
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0108 0.0085 0.1235
Echinococcus granulosus plasminogen activator inhibitor 2 0.0023 0.0003 0.0003
Brugia malayi EGF-like domain containing protein 0.0079 0.0057 0.0057
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0029 0.0009 0.0011
Loa Loa (eye worm) kelch domain-containing protein family protein 0.051 0.0475 0.0475
Schistosoma mansoni tyrosine kinase 0.0648 0.0608 0.0608
Echinococcus granulosus neuroendocrine convertase 2 0.6534 0.631 0.631
Onchocerca volvulus 0.0029 0.0009 0.0123
Brugia malayi hypothetical protein 0.0029 0.0009 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0009 0.0011
Brugia malayi Dopamine receptor 0.0029 0.0009 0.0009
Schistosoma mansoni apoptosis regulator bax 0.0053 0.0032 0.0032
Toxoplasma gondii histone lysine-specific demethylase 0.0142 0.0118 0.2807
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0136 0.0113 0.0113
Echinococcus multilocularis cubilin 0.0026 0.0006 0.0007
Onchocerca volvulus 0.0035 0.0014 0.0197
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0009 0.0009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2514 0.2416 0.3957
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Entamoeba histolytica hypothetical protein, conserved 0.0108 0.0085 0.1235
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0038 0.0017 0.0017
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0108 0.0085 0.0085
Onchocerca volvulus 0.0035 0.0014 0.0197
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0057 0.0036 0.0472
Loa Loa (eye worm) hypothetical protein 0.0699 0.0658 0.0658
Schistosoma mansoni hypothetical protein 0.0344 0.0314 0.0314
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.2059 0.1975 0.3235
Brugia malayi RE15519p 0.0029 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0059 0.0038 0.0549
Brugia malayi proprotein convertase 2 0.6534 0.631 0.631
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0148 0.0124 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0011 0.009
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0009 0.0009
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0017 0.0017
Plasmodium vivax LCCL domain-containing protein 0.0044 0.0023 0.0547
Brugia malayi beta-lactamase family protein 0.0113 0.009 0.009
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0031 0.001 0.001
Brugia malayi putative neuropeptide receptor NPR1 0.0029 0.0009 0.0009
Loa Loa (eye worm) acetyltransferase 0.0168 0.0144 0.0144
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0029 0.0009 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0017 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0009 0.0009
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0009 0.0009
Echinococcus granulosus 7TM GPCR rhodopsin 0.0029 0.0009 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0009 0.0009
Brugia malayi Calcitonin receptor-like protein seb-1 0.0199 0.0174 0.0174
Trypanosoma cruzi UDP-galactopyranose mutase 0.0142 0.0118 0.1662
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0009 0.0009
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0009 0.0011
Echinococcus multilocularis integrin beta 2 0.2338 0.2246 0.2805
Schistosoma mansoni cpg binding protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) fatty acid synthase 0.0079 0.0057 0.0057
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0016
Schistosoma mansoni memapsin-2 (A01 family) 0.0038 0.0017 0.0017
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Echinococcus granulosus glutamate NMDA receptor subunit 0.0258 0.0231 0.0231
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0009 0.0011
Brugia malayi metalloprotease 0.0025 0.0004 0.0004
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0053 0.0032 0.0032
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0113 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0053 0.0032 0.0032
Toxoplasma gondii subtilisin SUB9 0.0455 0.0421 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.0082 0.0082
Schistosoma mansoni myosin xvIII 0.0029 0.0009 0.0009
Brugia malayi neuropeptide F receptor 0.0029 0.0009 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0009 0.0011
Plasmodium vivax subtilisin-like protease 1 0.0455 0.0421 1
Onchocerca volvulus 0.0038 0.0017 0.024
Loa Loa (eye worm) hypothetical protein 0.0113 0.009 0.009
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.005 0.0029 0.0591
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0025 0.0005 0.0008
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0082 0.006 0.1322
Trichomonas vaginalis conserved hypothetical protein 0.0455 0.0421 0.069
Onchocerca volvulus 0.0035 0.0014 0.0197
Plasmodium falciparum plasmepsin IV 0.0038 0.0017 0.0408
Schistosoma mansoni amine GPCR 0.0029 0.0009 0.0009
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.0085 0.014
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0023 0.0547
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.0085 0.014
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.0085 0.014
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0108 0.0085 0.1202
Brugia malayi serpin 0.0023 0.0003 0.0003
Plasmodium vivax aspartyl proteinase, putative 0.0038 0.0017 0.0408
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0029 0.0009 0.0009
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0029 0.0009 0.0123
Plasmodium falciparum subtilisin-like protease 2 0.0455 0.0421 1
Toxoplasma gondii aspartyl protease ASP1 0.0038 0.0017 0.0408
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0108 0.0085 0.0106
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0009 0.0011
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0077 0.0055 0.0755
Mycobacterium tuberculosis Probable lipase LipE 0.0113 0.009 0.1268
Onchocerca volvulus Fatty acid synthase homolog 0.0144 0.012 0.1675
Echinococcus granulosus growth factor receptor bound protein 2 0.0126 0.0103 0.0103
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0031 0.001 0.0013
Brugia malayi hypothetical protein 0.0029 0.0009 0.0009
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0053 0.0032 0.0403
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0009 0.0011
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0009 0.0011
Brugia malayi SWIRM domain containing protein 0.0759 0.0715 0.0715
Loa Loa (eye worm) metalloprotease 0.0025 0.0004 0.0004
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0044 0.0023 0.0038
Echinococcus granulosus Tolloid protein 1 0.0026 0.0006 0.0006
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0019 0.0019
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0114 0.0114
Schistosoma mansoni discoidin domain receptor 0.0044 0.0023 0.0023
Loa Loa (eye worm) transcriptional regulator 0.0108 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0759 0.0715 0.0715
Plasmodium vivax subtilisin-like protease 2, putative 0.0455 0.0421 1
Trichomonas vaginalis conserved hypothetical protein 0.2059 0.1975 0.3235
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0094 0.0072 0.1708
Echinococcus granulosus cpg binding protein 0.0029 0.0009 0.0009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Giardia lamblia Neurogenic locus Notch protein precursor 0.0079 0.0057 0.0149
Schistosoma mansoni opsin-like receptor 0.0029 0.0009 0.0009
Brugia malayi Integrin alpha cytoplasmic region family protein 0.034 0.031 0.031
Toxoplasma gondii type I fatty acid synthase, putative 0.0082 0.006 0.1422
Mycobacterium tuberculosis Conserved protein 0.0113 0.009 0.1268
Plasmodium vivax hypothetical protein, conserved 0.0142 0.0118 0.2807
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0108 0.0085 0.0106
Loa Loa (eye worm) hypothetical protein 0.0072 0.0051 0.0051
Brugia malayi pregnancy-associated plasma protein-A 0.0035 0.0014 0.0014
Toxoplasma gondii bicoid-interacting protein BIN3 0.0053 0.0032 0.0761
Onchocerca volvulus 0.0029 0.0009 0.0123
Brugia malayi hypothetical protein 0.0116 0.0093 0.0093
Echinococcus multilocularis serotonin receptor 0.0029 0.0009 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0114 0.0114
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0009 0.0009
Brugia malayi hypothetical protein 0.0035 0.0014 0.0014
Brugia malayi larval opioid receptor 0.0029 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0026 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Plasmodium vivax LCCL domain-containing protein 0.0044 0.0023 0.0547
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0029 0.0009 0.0009
Loa Loa (eye worm) integrin alpha pat-2 0.0693 0.0652 0.0652
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0023 0.0038
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0168 0.0144 0.0144
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0114 0.0114
Echinococcus granulosus neuropilin nrp and tolloid tll 0.0026 0.0006 0.0006
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0029 0.0009 0.0009
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0142 0.0118 0.2733
Toxoplasma gondii aspartyl protease ASP3 0.0038 0.0017 0.0408
Loa Loa (eye worm) Carm1-pending protein 0.0053 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0031 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.2059 0.1975 0.3235
Toxoplasma gondii hypothetical protein 0.0079 0.0057 0.1356
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0009 0.0009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Echinococcus granulosus dro:myosuppressin receptor 0.0029 0.0009 0.0009
Brugia malayi GnHR receptor homolog 0.0029 0.0009 0.0009
Brugia malayi hypothetical protein 0.0023 0.0003 0.0003
Schistosoma mansoni amine GPCR 0.0029 0.0009 0.0009
Brugia malayi EGF-like domain containing protein 0.0079 0.0057 0.0057
Schistosoma mansoni serine protease inhibitors serpins 0.0023 0.0003 0.0003
Schistosoma mansoni histamine h1 receptor 0.0029 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0136 0.0113 0.0113
Onchocerca volvulus 0.0035 0.0014 0.0197
Echinococcus granulosus serine protease inhibitor 0.0023 0.0003 0.0003
Schistosoma mansoni cathepsin D (A01 family) 0.0038 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0104 0.0082 0.0082
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0082 0.006 0.0826
Mycobacterium ulcerans esterase/lipase LipP 0.0113 0.009 0.2046
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0455 0.0421 0.0421
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Plasmodium vivax aspartyl protease, putative 0.0038 0.0017 0.0408
Echinococcus multilocularis G protein coupled receptor 139 0.0029 0.0009 0.0011
Echinococcus multilocularis c4b binding protein beta chain 0.0035 0.0014 0.0018
Mycobacterium ulcerans polyketide synthase Pks13 0.0116 0.0093 0.2134
Plasmodium falciparum plasmepsin VIII, putative 0.0038 0.0017 0.0408
Brugia malayi serpin 0.0023 0.0003 0.0003
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0089 0.0067 0.0067
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0066 0.0045 0.0963
Mycobacterium tuberculosis Probable lipase LipD 0.0113 0.009 0.1268
Loa Loa (eye worm) hypothetical protein 0.0142 0.0118 0.0118
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0029 0.0009 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.009 0.1244
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0032 0.0012 0.0111
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.2059 0.1975 0.3235
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0013
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0029 0.0009 0.0009
Trypanosoma brucei hypothetical protein, conserved 0.0113 0.009 0.1244
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0038 0.0038
Brugia malayi Pepsin A precursor 0.0038 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0026 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0029 0.0009 0.0009
Schistosoma mansoni amine oxidase 0.0142 0.0118 0.0118
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0026 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) integrin beta-2 0.3165 0.3047 0.3047
Echinococcus granulosus neuropeptide receptor A26 0.0029 0.0009 0.0009
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0053 0.0032 0.0052
Brugia malayi hypothetical protein 0.0029 0.0009 0.0009
Echinococcus multilocularis integrin alpha ps 0.0201 0.0176 0.022
Echinococcus granulosus histone acetyltransferase KAT2B 0.005 0.0029 0.0029
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0455 0.0421 0.6082
Echinococcus granulosus orexin receptor type 2 0.0029 0.0009 0.0009
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0199 0.0174 0.0174
Brugia malayi hypothetical protein 0.0029 0.0009 0.0009
Brugia malayi Reprolysin 0.0052 0.0031 0.0031
Brugia malayi hypothetical protein 0.0025 0.0004 0.0004
Echinococcus multilocularis cpg binding protein 0.0029 0.0009 0.0011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0114 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.2059 0.1975 0.3235
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0009 0.0009
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0025 0.0025
Brugia malayi latrophilin 2 splice variant baaae 0.0136 0.0113 0.0113
Loa Loa (eye worm) acyl carrier protein 0.0037 0.0016 0.0016
Echinococcus multilocularis fibrillin 2 0.0079 0.0057 0.0071
Entamoeba histolytica SWIRM domain protein 0.0059 0.0038 0.0549
Echinococcus granulosus MAM 0.0072 0.0051 0.0051
Echinococcus multilocularis SWI:SNF complex subunit SMARCC2 0.0059 0.0038 0.0047
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0484 0.045 0.045
Brugia malayi Melatonin receptor type 1A 0.0029 0.0009 0.0009
Brugia malayi Angiotensin-converting enzyme family protein 0.0622 0.0584 0.0584
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0481 0.0446 0.6449
Loa Loa (eye worm) hypothetical protein 0.0201 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Plasmodium falciparum plasmepsin VI 0.0038 0.0017 0.0408
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0029 0.0009 0.0009
Giardia lamblia Tenascin-like 0.0079 0.0057 0.0149
Loa Loa (eye worm) hypothetical protein 0.0113 0.009 0.009
Entamoeba histolytica serine protease inhibitor, putative 0.0023 0.0003 0.0038
Onchocerca volvulus 0.0026 0.0006 0.008
Echinococcus multilocularis MAM 0.0072 0.0051 0.0063
Plasmodium falciparum apical sushi protein 0.0035 0.0014 0.0334
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0009 0.0011
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0053 0.0053
Leishmania major hypothetical protein, conserved 0.0031 0.0011 0.009
Loa Loa (eye worm) hypothetical protein 0.0113 0.009 0.009
Echinococcus multilocularis Tolloid protein 1 0.0026 0.0006 0.0007
Brugia malayi Kelch motif family protein 0.051 0.0475 0.0475
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0095 0.0072 0.0072
Onchocerca volvulus 0.0113 0.009 0.1253
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0009 0.0009
Onchocerca volvulus 0.0455 0.0421 0.5888
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.0103 0.0103
Trichomonas vaginalis bromodomain-containing protein, putative 0.005 0.0029 0.0047
Schistosoma mansoni tar DNA-binding protein 0.0061 0.004 0.004
Loa Loa (eye worm) transcriptional regulator 0.0732 0.069 0.069
Echinococcus multilocularis allatostatin A receptor 0.0029 0.0009 0.0011
Loa Loa (eye worm) serpin 0.0023 0.0003 0.0003
Schistosoma mansoni glutamate receptor NMDA 0.0046 0.0025 0.0025
Echinococcus multilocularis Coagulation factor 5 8 type, C terminal 0.0044 0.0023 0.0029
Loa Loa (eye worm) TYRA-2 protein 0.0029 0.0009 0.0009
Brugia malayi G protein-coupled receptor 0.0029 0.0009 0.0009
Onchocerca volvulus 0.0044 0.0023 0.0322
Loa Loa (eye worm) hypothetical protein 0.034 0.031 0.031
Brugia malayi amine oxidase, flavin-containing family protein 0.0201 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0089 0.0067 0.0067
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.0042 0.0052
Loa Loa (eye worm) melatonin receptor type 1A 0.0029 0.0009 0.0009
Echinococcus granulosus membrane bound transcription factor site 1 0.0455 0.0421 0.0421
Plasmodium falciparum plasmepsin IX 0.0038 0.0017 0.0408
Echinococcus multilocularis discoidin domain containing receptor 2 0.0044 0.0023 0.0029
Echinococcus multilocularis discoidin domain containing receptor 2 0.0044 0.0023 0.0029
Echinococcus multilocularis orexin receptor type 2 0.0029 0.0009 0.0011
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0732 0.069 1
Mycobacterium leprae PROBABLE CONSERVED TRANSMEMBRANE PROTEIN 0.0044 0.0023 0.0437
Toxoplasma gondii subtilisin SUB8 0.0455 0.0421 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0017 0.0017
Loa Loa (eye worm) serpin protein 6 0.0023 0.0003 0.0003
Brugia malayi Serotonin receptor 0.0029 0.0009 0.0009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0455 0.0421 0.069
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0046 0.0025 0.0025
Brugia malayi CXXC zinc finger family protein 0.0028 0.0008 0.0008
Brugia malayi hypothetical protein 0.0142 0.0118 0.0118
Echinococcus multilocularis nuclear receptor 2C2 associated protein 0.0044 0.0023 0.0029
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.005 0.0029 0.0678
Onchocerca volvulus Neuropeptide F receptor homolog 0.0029 0.0009 0.0123
Echinococcus granulosus Furin 1 0.2514 0.2416 0.2416
Echinococcus multilocularis geminin 0.0344 0.0314 0.0392
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0082 0.006 0.0826
Schistosoma mansoni ATP-binding cassette transporter 0.0031 0.001 0.001
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0061 0.004 0.0856
Echinococcus granulosus 7tm_1 domain containing protein 0.0029 0.0009 0.0009
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0029 0.0009 0.0011
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0038 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0097 0.0074 0.0074
Brugia malayi Sushi domain 0.0035 0.0014 0.0014
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0009 0.0009
Brugia malayi Serotonin receptor 0.0029 0.0009 0.0009
Entamoeba histolytica PH domain containing protein kinase, putative 0.0077 0.0056 0.0806
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0009 0.0011
Onchocerca volvulus 0.0079 0.0057 0.0799
Loa Loa (eye worm) hypothetical protein 0.0353 0.0322 0.0322
Echinococcus granulosus geminin 0.0344 0.0314 0.0314
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0053 0.0032 0.0052
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0009 0.0009
Brugia malayi Dopamine receptor protein 2 0.0029 0.0009 0.0009
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.2514 0.2416 0.2416
Plasmodium vivax hypothetical protein, conserved 0.0108 0.0085 0.2023
Echinococcus granulosus protein kinase c epsilon type 0.0095 0.0072 0.0072
Trichomonas vaginalis beta-hexosaminidase B, putative 0.0044 0.0023 0.0038
Toxoplasma gondii rhoptry neck protein RON9 0.0035 0.0014 0.0334
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0029 0.0009 0.0011
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.004 0.002 0.0466
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.0085 0.014
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0029 0.0009 0.0011
Echinococcus granulosus discoidin domain containing receptor 2 0.0044 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0455 0.0421 0.6195
Onchocerca volvulus 0.0072 0.0051 0.071
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0017 0.0017
Echinococcus granulosus discoidin domain receptor 0.0044 0.0023 0.0023
Brugia malayi ADAMTS-like protease 0.0052 0.0031 0.0031
Schistosoma mansoni integrin alpha-ps 0.0201 0.0176 0.0176
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0009 0.0009
Brugia malayi CUB domain containing protein 0.0026 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0029 0.0009 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0061 0.004 0.004
Schistosoma mansoni site-1 peptidase (S08 family) 0.0455 0.0421 0.0421
Schistosoma mansoni glutamate receptor NMDA 0.0258 0.0231 0.0231
Loa Loa (eye worm) sirtuin 4 0.0108 0.0085 0.0085
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0025 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0009 0.0009
Brugia malayi acetyltransferase, GNAT family protein 0.0168 0.0144 0.0144
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0053 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0059 0.0038 0.0038
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0031 0.001 0.001
Echinococcus granulosus discoidin domain containing receptor 2 0.0044 0.0023 0.0023
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.004 0.004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0138 0.0114 0.0114
Mycobacterium leprae Polyketide synthase Pks13 0.0116 0.0093 0.2124
Onchocerca volvulus 0.0029 0.0009 0.0123
Echinococcus granulosus serotonin receptor 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Brugia malayi angiogenesis inhibito 0.0052 0.0031 0.0031
Echinococcus multilocularis cubilin 0.0026 0.0006 0.0007
Mycobacterium tuberculosis Probable thioesterase TesA 0.0066 0.0045 0.0603
Onchocerca volvulus 0.0113 0.009 0.1253
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0029 0.0009 0.0009
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0004 0.0104
Toxoplasma gondii F5/8 type C domain-containing protein 0.0044 0.0023 0.0547
Loa Loa (eye worm) hypothetical protein 0.0248 0.0221 0.0221
Brugia malayi G-protein coupled receptor 0.0029 0.0009 0.0009
Onchocerca volvulus 0.0035 0.0014 0.0197
Echinococcus multilocularis neuropeptide s receptor 0.0029 0.0009 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0009 0.0009
Schistosoma mansoni protein kinase 0.0127 0.0103 0.0103
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0009 0.0009

Activities

Activity type Activity value Assay description Source Reference
Relative protection (binding) < 0.1 Protective effect of compound was tested by the inhibition of Proteus vulgaris beta-lactamase relative to clavulanic acid as 1 ChEMBL. No reference
Relative protection (binding) = 0.4 Protective effect tested by the inhibition of Staphylococcus aureus beta-lactamase relative to clavulanic acid ChEMBL. No reference
Relative protection (binding) < 0.1 Protective effect of compound was tested by the inhibition of Proteus vulgaris beta-lactamase relative to clavulanic acid as 1 ChEMBL. No reference
Relative protection (binding) = 0.4 Protective effect tested by the inhibition of Staphylococcus aureus beta-lactamase relative to clavulanic acid ChEMBL. No reference
T1/2 (ADMET) = 13.7 hr T1/2 (phosphate buffer pH 7.0 @ 28 degree C) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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