Detailed information for compound 1137396

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 299.407 | Formula: C19H25NO2
  • H donors: 3 H acceptors: 2 LogP: 3.46 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(N[C@H]([C@@H](c1ccc(cc1)O)O)C)CCc1ccccc1
  • InChi: 1S/C19H25NO2/c1-14(8-9-16-6-4-3-5-7-16)20-15(2)19(22)17-10-12-18(21)13-11-17/h3-7,10-15,19-22H,8-9H2,1-2H3/t14?,15-,19-/m0/s1
  • InChiKey: PTGXAUBQBSGPKF-KDBUZZBASA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi reverse transcriptase 0.0027 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0052 0.0117 0.0117
Trypanosoma brucei hypothetical protein, conserved 0.0116 0.0326 0.0324
Schistosoma mansoni phosphoglucomutase 0.0088 0.0236 0.0236
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0036 0.0036
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0037 0.032
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0021 0.0018
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0103 0.0103
Onchocerca volvulus 0.2707 0.8854 1
Toxoplasma gondii kinase, pfkB family protein 0.0348 0.1092 0.109
Brugia malayi Zinc knuckle family protein 0.0027 0.0036 0.0036
Brugia malayi Ribokinase 0.0348 0.1092 0.1092
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0046 0.5705
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0023 0.0022 0.0178
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0003 0.0003
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0103 0.0103
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.0408 0.0408
Treponema pallidum ribonuclease H (rnhA) 0.0088 0.0236 1
Loa Loa (eye worm) hypothetical protein 0.0348 0.1092 0.1092
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0064
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0089 0.0089
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0063
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0027 0.0036 0.0036
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0148 0.0146
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Schistosoma mansoni single-minded 0.0059 0.0139 0.0139
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.0348 0.1092 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0032 0.0051 0.0051
Trichomonas vaginalis NeSL-1_NeSL reverse transcriptases, putative 0.0027 0.0036 0.0211
Giardia lamblia Ribonuclease H 0.0088 0.0236 0.2062
Leishmania major adenosine kinase-like protein 0.0348 0.1092 0.109
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0027 0.0036 0.0038
Leishmania major ribonuclease H1, putative 0.0088 0.0236 0.0234
Leishmania major hypothetical protein, conserved 0.003 0.0046 0.0044
Leishmania major GTP-binding protein, putative 0.0021 0.0014 0.0011
Mycobacterium ulcerans fructokinase, PfkB 0.0348 0.1092 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0038 0.0036
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0082 0.0082
Trypanosoma cruzi ribokinase, putative 0.0348 0.1092 0.109
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0036 0.0036
Loa Loa (eye worm) acetyltransferase 0.014 0.0408 0.0408
Schistosoma mansoni scy1(yeast) protein kinase-like 0.0027 0.0036 0.0036
Toxoplasma gondii ribonuclease HI protein 0.0088 0.0236 0.0234
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0148 0.0148
Loa Loa (eye worm) cytochrome P450 family protein 0.004 0.0078 0.0078
Brugia malayi cytochrome P450 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0027 0.0036 0.0036
Onchocerca volvulus 0.0043 0.0089 0.0097
Onchocerca volvulus 0.0348 0.1092 0.123
Mycobacterium tuberculosis Adenosine kinase 0.0348 0.1092 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0014 0.0011
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0036 0.0036
Trypanosoma cruzi adenosine kinase, putative 0.0348 0.1092 0.109
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0117 0.0117
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0046 0.5705
Schistosoma mansoni ran 0.0021 0.0014 0.0014
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0003 0.0003
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0014 0.0011
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Brugia malayi hypothetical protein 0.0027 0.0036 0.0036
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0348 0.1092 0.1092
Onchocerca volvulus 0.0027 0.0036 0.0038
Leishmania major adenosine kinase, putative 0.3056 1 1
Mycobacterium ulcerans carbohydrate kinase CbhK 0.0348 0.1092 1
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Echinococcus granulosus Ankyrin 0.0018 0.0004 0.0004
Echinococcus multilocularis RNA directed DNA polymerase 0.0027 0.0036 0.0036
Echinococcus granulosus RNA directed DNA polymerase 0.0027 0.0036 0.0036
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0148 0.0146
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0101 0.028 0.028
Trypanosoma brucei ingi protein (ORF1) 0.0116 0.0326 0.0324
Onchocerca volvulus 0.008 0.0208 0.0231
Schistosoma mansoni hypothetical protein 0.0027 0.0036 0.0036
Mycobacterium tuberculosis Ribokinase RbsK 0.0348 0.1092 1
Mycobacterium tuberculosis Possible maturase 0.0027 0.0036 0.0314
Plasmodium falciparum importin beta, putative 0.0028 0.0038 0.4265
Echinococcus multilocularis ribonuclease H1 0.0088 0.0236 0.0236
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0014 0.0011
Trypanosoma brucei adenosine kinase, putative 0.3056 1 1
Leishmania major cytochrome p450-like protein 0.0028 0.0037 0.0035
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0063 0.0063
Trypanosoma cruzi ribonuclease H1, putative 0.0088 0.0236 0.0234
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0014 0.0014
Echinococcus granulosus jun protein 0.0101 0.028 0.028
Brugia malayi hypothetical protein 0.003 0.0046 0.0046
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0014 0.0011
Trypanosoma brucei SLACS retrotransposable element (part), putative 0.0027 0.0036 0.0034
Echinococcus multilocularis nmda type glutamate receptor 0.0032 0.0051 0.0051
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0348 0.1092 1
Echinococcus granulosus ribonuclease H1 0.0088 0.0236 0.0236
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0148 0.0148
Brugia malayi reverse transcriptase 0.0027 0.0036 0.0036
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0088 0.0236 0.5
Trichomonas vaginalis ribokinase, putative 0.0348 0.1092 1
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0003 0.0003
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0046 0.0044
Leishmania major importin beta-1 subunit, putative 0.0023 0.0021 0.0018
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0037 0.0037
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0116 0.0326 0.0324
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0089 0.0797
Schistosoma mansoni netrin receptor unc5 0.0017 0.0003 0.0003
Plasmodium vivax importin-beta 2, putative 0.0028 0.0038 0.3557
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Leishmania major putative PfkB family sugar kinase 0.0348 0.1092 0.109
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.0408 0.0408
Schistosoma mansoni aryl hydrocarbon receptor 0.0059 0.0139 0.0139
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0103 0.0103
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0027 0.0036 0.0211
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0038 0.0036
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0148 0.125
Echinococcus multilocularis ribokinase 0.0348 0.1092 0.1092
Loa Loa (eye worm) hypothetical protein 0.3056 1 1
Trypanosoma brucei Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative 0.0027 0.0036 0.0034
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0036 0.0036
Trypanosoma brucei ribonuclease H1 0.0088 0.0236 0.0234
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0027 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0197 0.0595 0.0595
Brugia malayi hypothetical protein 0.002 0.0011 0.0011
Brugia malayi Death domain containing protein 0.0017 0.0003 0.0003
Brugia malayi Uncoordinated protein 44 0.0017 0.0003 0.0003
Trichomonas vaginalis ribonuclease H1, putative 0.0088 0.0236 0.2062
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0036 0.0036
Schistosoma mansoni ribokinase 0.0348 0.1092 0.1092
Leishmania major tagatose-6-phosphate kinase-like protein 0.0348 0.1092 0.109
Trypanosoma brucei adenosine kinase, putative 0.3056 1 1
Onchocerca volvulus Ribonuclease H1 homolog 0.0088 0.0236 0.0263
Leishmania major ribokinase, putative 0.0348 0.1092 0.109
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0071 0.0528
Brugia malayi Cytochrome P450 family protein 0.004 0.0078 0.0078
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Echinococcus granulosus adenosine kinase 0.3056 1 1
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.0408 0.0408
Schistosoma mansoni protein kinase 0.0027 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Trichomonas vaginalis reverse transcriptase [C. elegans], putative 0.0027 0.0036 0.0211
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0148 0.0146
Loa Loa (eye worm) hypothetical protein 0.0028 0.0038 0.0038
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0148 0.0148
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0148 0.0146
Schistosoma mansoni hypothetical protein 0.0298 0.0928 0.0928
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0239 0.0239
Brugia malayi RNase H family protein 0.0088 0.0236 0.0236
Echinococcus granulosus death domain containing protein 0.0017 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0082 0.0217 0.0217
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0036 0.0034
Trypanosoma brucei unspecified product 0.0116 0.0326 0.0324
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0027 0.0036 0.0211
Brugia malayi bZIP transcription factor family protein 0.0101 0.028 0.028
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0027 0.0036 0.0211
Giardia lamblia Ribokinase 0.0348 0.1092 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0271 0.0271
Onchocerca volvulus 0.0027 0.0036 0.0038
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0148 0.0148
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0239 0.0239
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0021 0.0064
Trypanosoma cruzi adenosine kinase, putative 0.0348 0.1092 0.109
Brugia malayi hypothetical protein 0.0027 0.0036 0.0036
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.0395 0.0395
Schistosoma mansoni hypothetical protein 0.0062 0.0152 0.0152
Schistosoma mansoni adenosine kinase 0.3056 1 1
Onchocerca volvulus Putative pyridoxal kinase 0.0348 0.1092 0.123
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0014 0.0014
Brugia malayi reverse transcriptase 0.0027 0.0036 0.0036
Brugia malayi RNA, U transporter 1 0.0079 0.0208 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0148 0.0148
Toxoplasma gondii kinase, pfkB family protein 0.3056 1 1
Schistosoma mansoni phosphoglucomutase 0.0088 0.0236 0.0236
Trypanosoma cruzi ribonuclease H1, putative 0.0088 0.0236 0.0234
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0021 0.0064
Brugia malayi RNase H family protein 0.0088 0.0236 0.0236
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0148 0.125
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0027 0.0036 0.0036
Trypanosoma brucei ribokinase, putative 0.0348 0.1092 0.109
Brugia malayi MAP kinase sur-1 0.0062 0.0148 0.0148
Brugia malayi hypoxia-induced factor 1 0.0182 0.0544 0.0544
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0348 0.1092 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0082 0.008
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0038 0.0036
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0018 0.0004 0.0004
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0117 0.0117
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0082 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0103 0.0103
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0038 0.0038
Trichomonas vaginalis reverse transcriptases, putative 0.0027 0.0036 0.0211
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0101 0.028 0.028
Trypanosoma brucei SLACS reverse transcriptase, putative 0.0027 0.0036 0.0034
Entamoeba histolytica fructokinase, putative 0.0348 0.1092 1
Schistosoma mansoni jun-related protein 0.0082 0.0217 0.0217
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0348 0.1092 0.1092
Echinococcus granulosus ribokinase 0.0348 0.1092 0.1092
Trypanosoma brucei protein kinase, putative 0.0062 0.0148 0.0146
Leishmania major tagatose-6-phosphate kinase-like protein 0.0348 0.1092 0.109
Schistosoma mansoni importin beta-1 0.0028 0.0038 0.0038
Brugia malayi RNase H family protein 0.0088 0.0236 0.0236
Schistosoma mansoni phosphoglucomutase 0.0088 0.0236 0.0236
Chlamydia trachomatis glutamine binding protein 0.0023 0.0022 0.5
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0148 0.0146
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0071 0.0528
Echinococcus granulosus KRAB A domain containing protein 0.0027 0.0036 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0046 0.0044
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0148 0.0146
Echinococcus multilocularis jun protein 0.0101 0.028 0.028
Brugia malayi Cytochrome P450 family protein 0.0017 0.0002 0.0002
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0036 0.0036
Echinococcus granulosus single minded 2 0.0043 0.0089 0.0089
Echinococcus multilocularis snurportin 1 0.0298 0.0928 0.0928
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0027 0.0036 0.0036
Trypanosoma brucei RNA helicase, putative 0.1214 0.3939 0.3938
Brugia malayi hypothetical protein 0.008 0.0208 0.0208
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0082 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0348 0.1092 1
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0027 0.0036 0.0036
Trypanosoma brucei ingi protein (ORF1) 0.0116 0.0326 0.0324
Trichomonas vaginalis ribokinase, putative 0.0348 0.1092 1
Schistosoma mansoni hypothetical protein 0.1214 0.3939 0.3939
Trypanosoma brucei ribokinase, putative 0.0348 0.1092 0.109
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0103 0.0103
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0148 0.125
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0037 0.0035
Brugia malayi Cytochrome P450 family protein 0.0028 0.0037 0.0037
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.003 0.0046 0.0046
Echinococcus granulosus importin subunit beta 1 0.0028 0.0038 0.0038
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0021 0.0064
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0023 0.0022 0.0178
Brugia malayi Zinc knuckle family protein 0.0027 0.0036 0.0036
Brugia malayi hypothetical protein 0.0027 0.0036 0.0036
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0003 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0103 0.0103
Entamoeba histolytica kinase, PfkB family 0.0348 0.1092 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Echinococcus multilocularis Ankyrin 0.0018 0.0004 0.0004
Brugia malayi hypothetical protein 0.0027 0.0036 0.0036
Brugia malayi hypothetical protein 0.0197 0.0595 0.0595
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0103 0.0103
Echinococcus granulosus snurportin 1 0.0298 0.0928 0.0928
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0037 0.0037
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0148 0.125
Echinococcus multilocularis 0.0017 0.0002 0.0002
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0003 0.0003
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0036 0.0036
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0046 0.0044
Trichomonas vaginalis reverse transcriptases, putative 0.0027 0.0036 0.0211
Brugia malayi PAS domain containing protein 0.0059 0.0139 0.0139
Loa Loa (eye worm) cytochrome P450 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.0348 0.1092 0.1092
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0023 0.0022 0.5
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0148 0.0146
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0037 0.0035
Echinococcus multilocularis adenosine kinase 0.3056 1 1
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0046 0.4758
Schistosoma mansoni cytochrome P450 0.0017 0.0002 0.0002
Trichomonas vaginalis ribokinase, putative 0.0348 0.1092 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0014 0.0014
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0038 0.0038
Trypanosoma cruzi adenosine kinase, putative 0.3056 1 1
Schistosoma mansoni ran 0.0021 0.0014 0.0014
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0089 0.0089
Loa Loa (eye worm) hypoxia-induced factor 1 0.0182 0.0544 0.0544
Schistosoma mansoni hypothetical protein 0.0035 0.0063 0.0063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0103 0.0103
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0117 0.0117
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0036 0.0036
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0071 1
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0027 0.0036 0.0211
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0003
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0036 0.0036
Onchocerca volvulus Ribokinase homolog 0.0348 0.1092 0.123
Brugia malayi Importin beta-1 subunit 0.0028 0.0038 0.0038
Trypanosoma cruzi adenosine kinase, putative 0.3056 1 1
Brugia malayi Protein kinase domain containing protein 0.0018 0.0005 0.0005
Giardia lamblia Reverse transcriptase/endonuclease 0.0027 0.0036 0.0211
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0037 0.0037
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0082 0.0633
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0046 0.0044
Echinococcus granulosus nmda type glutamate receptor 0.0032 0.0051 0.0051
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0148 0.125
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0348 0.1092 0.1092
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.0928 0.0928
Brugia malayi Cytochrome P450 family protein 0.0028 0.0037 0.0037
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0103 0.0103
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0003 0.0003
Schistosoma mansoni adenosine kinase 0.3056 1 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0082 0.0633
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0037 0.0035
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0148 0.0146
Mycobacterium leprae Probable adenosine kinase adk 0.0348 0.1092 1
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0002 0.0002
Leishmania major adenosine kinase-like protein 0.0348 0.1092 0.109
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0148 0.0148
Entamoeba histolytica ribokinase, putative 0.0348 0.1092 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.