Detailed information for compound 1138845

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 554.63 | Formula: C27H42N2O10
  • H donors: 7 H acceptors: 8 LogP: 0.51 Rotable bonds: 19
    Rule of 5 violations (Lipinski): 3
  • SMILES: OC[C@H]([C@H](C1OC(OCCCCCCCCC(=O)NCc2ccccc2)(CC(C1NC(=O)C)O)C(=O)O)O)O
  • InChi: 1S/C27H42N2O10/c1-18(31)29-23-20(32)15-27(26(36)37,39-25(23)24(35)21(33)17-30)38-14-10-5-3-2-4-9-13-22(34)28-16-19-11-7-6-8-12-19/h6-8,11-12,20-21,23-25,30,32-33,35H,2-5,9-10,13-17H2,1H3,(H,28,34)(H,29,31)(H,36,37)/t20?,21-,23?,24-,25?,27?/m1/s1
  • InChiKey: YIZGJSUCAWBTKH-VEJNWMLKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.0129 0.0207
Schistosoma mansoni hypothetical protein 0.0048 0.0044 0.0044
Mycobacterium ulcerans O-methyltransferase 0.0577 0.0985 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Schistosoma mansoni o-methyltransferase 0.006 0.0065 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0038 0.0026 0.012
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Toxoplasma gondii heat shock protein HSP90 0.0142 0.0211 0.0208
Brugia malayi photoreceptor-specific nuclear receptor 0.0274 0.0445 0.2352
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0076 0.0388
Brugia malayi Methionine aminopeptidase protein type I 0.005 0.0048 0.0241
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0026 0.0005 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0026 0.0072
Entamoeba histolytica cysteine proteinase, putative 0.0073 0.0088 0.1762
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.5644 1 1
Echinococcus granulosus caspase 2 0.0027 0.0005 0.0003
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0107 0.0149 0.0498
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.5644 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Brugia malayi bZIP transcription factor family protein 0.0084 0.0107 0.0558
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0029 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0274 0.0445 0.2349
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Echinococcus granulosus microtubule associated protein 2 0.1481 0.2593 0.8895
Leishmania major hypothetical protein, conserved 0.0107 0.0149 0.0503
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0029 0.0009 0.0009
Toxoplasma gondii Hsp90 domain-containing protein 0.0213 0.0337 0.0334
Leishmania major heat shock protein, putative 0.007 0.0082 0.0273
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0064 0.0206
Schistosoma mansoni hypothetical protein 0.1083 0.1886 0.1886
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0004 0.0001
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0047 0.0235
Schistosoma mansoni hypothetical protein 0.0169 0.0259 0.0259
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0026 0.0075
Plasmodium vivax DNA topoisomerase II, putative 0.0026 0.0005 0.0002
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0026 0.0074
Echinococcus granulosus TRP transient receptor potential channel 0.0107 0.0149 0.0498
Loa Loa (eye worm) glutathione reductase 0.0038 0.0025 0.0119
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0066 0.0212
Mycobacterium tuberculosis Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) 0.0034 0.0018 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0138 0.0203 0.032
Brugia malayi CHE-14 protein 0.0042 0.0033 0.0164
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.2159 0.38 0.3798
Trichomonas vaginalis sensor histidine kinase, putative 0.0026 0.0005 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0138 0.0203 0.032
Plasmodium vivax methionine aminopeptidase 1b, putative 0.005 0.0048 0.0045
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0138 0.0203 0.02
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.0212 0.2114
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Giardia lamblia Cathepsin L precursor 0.0029 0.0009 0.0005
Trypanosoma brucei metacaspase 5, putative 0.0027 0.0005 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0088 0.0134
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0029 0.0009 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0478 0.0763
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0033 0.0099
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0076 0.0385
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Echinococcus multilocularis potassium voltage gated channel protein 0.0107 0.0149 0.0498
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0026 0.0005 0.0001
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0107 0.0149 0.0149
Schistosoma mansoni heat shock protein 0.0142 0.0211 0.0211
Treponema pallidum replicative DNA helicase (dnaB) 0.0386 0.0645 1
Loa Loa (eye worm) hypothetical protein 0.016 0.0243 0.1273
Brugia malayi Blistered cuticle protein 3 0.0026 0.0005 0.0013
Echinococcus granulosus methionyl aminopeptidase 2 0.0047 0.0042 0.0129
Brugia malayi Cathepsin L-like precursor 0.0138 0.0203 0.1066
Echinococcus multilocularis cathepsin b 0.016 0.0243 0.0818
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0203 0.963
Schistosoma mansoni hypothetical protein 0.0041 0.0031 0.0031
Onchocerca volvulus 0.0026 0.0005 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0038 0.0026 0.012
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.2159 0.38 0.3798
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0004 0.0008
Echinococcus granulosus cathepsin b 0.016 0.0243 0.0818
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0107 0.0149 0.078
Plasmodium falciparum methionine aminopeptidase 1b, putative 0.005 0.0048 0.0045
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0044 0.0037 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0038 0.0026 0.0123
Schistosoma mansoni voltage-gated ion channel 0.0107 0.0149 0.0149
Brugia malayi Endoplasmin precursor 0.0142 0.0211 0.1107
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Brugia malayi Hsp90 protein 0.007 0.0082 0.0425
Loa Loa (eye worm) initiation factor 2-associated protein 0.0047 0.0042 0.0207
Trypanosoma cruzi major cysteine proteinase, putative 0.0029 0.0009 0.0262
Plasmodium vivax vivapain-2 0.0138 0.0203 0.02
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0027 0.0005 0.0015
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0107 0.0149 0.078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0203 0.963
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Brugia malayi cathepsin Z-like cysteine proteinase 0.0029 0.0009 0.0036
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0071 0.0071
Onchocerca volvulus Cathepsin L homolog 0.0138 0.0203 0.2678
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0005 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0009 0.0008
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0073 0.0088 0.0088
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0005 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0029 0.0009 0.0008
Giardia lamblia Dipeptidyl-peptidase I precursor 0.2159 0.38 0.3797
Echinococcus granulosus tar DNA binding protein 0.0063 0.0071 0.0228
Chlamydia trachomatis methionine aminopeptidase 0.0034 0.0018 0.0214
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0026 0.0005 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0038 0.0026 0.0123
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0033
Toxoplasma gondii proteasome subunit beta type, putative 0.007 0.0083 0.008
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0026 0.0005 0.0001
Loa Loa (eye worm) steroid hormone receptor 0.0038 0.0026 0.012
Echinococcus granulosus voltage gated potassium channel 0.0107 0.0149 0.0498
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0066 0.0066
Entamoeba histolytica methionine aminopeptidase, putative 0.0047 0.0042 0.0793
Onchocerca volvulus 0.0138 0.0203 0.2678
Echinococcus multilocularis musashi 0.0058 0.0061 0.0195
Giardia lamblia Cathepsin L precursor 0.0029 0.0009 0.0005
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.016 0.0243 0.0243
Loa Loa (eye worm) voltage-gated potassium channel 0.0107 0.0149 0.0778
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0107 0.0149 0.0149
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0038 0.0026 0.012
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0107 0.0149 0.0498
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0009 0.0036
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0107 0.0149 0.0234
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0038 0.0026 0.0072
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0089 0.0291
Leishmania major cathepsin L-like protease 0.0138 0.0203 0.0688
Echinococcus granulosus caspase 8 0.0027 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0034 0.0019 0.0084
Leishmania major mitochondrial DNA topoisomerase II 0.0026 0.0005 0.0006
Echinococcus multilocularis Niemann Pick C1 protein 0.0141 0.0208 0.0701
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0478 0.0763
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0038 0.0026 0.012
Brugia malayi hypothetical protein 0.0236 0.0379 0.1998
Trypanosoma cruzi heat shock protein 85, putative 0.0142 0.0211 0.8676
Onchocerca volvulus 0.0107 0.0149 0.1952
Trypanosoma cruzi metacaspase 5, putative 0.0027 0.0005 0.0099
Brugia malayi Proteasome A-type and B-type family protein 0.007 0.0083 0.0426
Echinococcus multilocularis cathepsin L cysteine protease 0.0138 0.0203 0.0683
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0009 0.0008
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0005 0.0002
Toxoplasma gondii hypothetical protein 0.0107 0.0149 0.0146
Brugia malayi cathepsin Z-like cysteine proteinase 0.0029 0.0009 0.0036
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.5644 1 1
Trypanosoma cruzi metacaspase, putative 0.0027 0.0005 0.0099
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0107 0.0149 0.0498
Loa Loa (eye worm) hypothetical protein 0.0047 0.0042 0.0205
Loa Loa (eye worm) voltage-gated potassium channel 0.0107 0.0149 0.0778
Brugia malayi O-methyltransferase family protein 0.006 0.0065 0.0331
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0107 0.0149 0.0498
Plasmodium falciparum glutathione reductase 0.0038 0.0025 0.0022
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0107 0.0149 0.0149
Schistosoma mansoni hypothetical protein 0.0068 0.0079 0.0079
Giardia lamblia Cathepsin L-like protease 0.0029 0.0009 0.0005
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0033 0.0099
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0073 0.0088 0.0088
Loa Loa (eye worm) twinkle helicase 0.011 0.0154 0.0805
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.0026 0.0123
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.1083 0.1886 0.6464
Brugia malayi Probable ATP-dependent helicase DHX35 0.0064 0.0072 0.0367
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0646
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0026 0.0005 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0005 0.0001
Trypanosoma brucei heat shock protein, putative 0.0142 0.0211 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0063 0.02
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0033
Echinococcus multilocularis potassium large conductance calcium activated 0.0107 0.0149 0.0498
Schistosoma mansoni DNA topoisomerase II 0.0026 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Brugia malayi hypothetical protein 0.0122 0.0176 0.0922
Chlamydia trachomatis recombinase RecA 0.0108 0.015 0.2267
Echinococcus granulosus peroxidasin 0.0026 0.0005 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.0133 0.0442
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0386 0.0645 0.3236
Schistosoma mansoni hypothetical protein 0.0169 0.0259 0.0259
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0026 0.0005 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0138 0.0203 0.032
Echinococcus granulosus endoplasmin 0.012 0.0171 0.0572
Plasmodium falciparum thioredoxin reductase 0.0038 0.0025 0.0022
Echinococcus multilocularis protein patched 0.0042 0.0033 0.0099
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.0379 0.1286
Loa Loa (eye worm) hypothetical protein 0.0122 0.0176 0.0919
Onchocerca volvulus Protein ultraspiracle homolog 0.0038 0.0026 0.028
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0107 0.0149 0.0149
Trypanosoma cruzi DNA repair protein, putative 0.0033 0.0017 0.0595
Plasmodium falciparum serine repeat antigen 1 0.0029 0.0009 0.0006
Trypanosoma cruzi heat shock protein 85, putative 0.0142 0.0211 0.8676
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0029 0.0009 0.0033
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.0129 0.0626
Schistosoma mansoni cathepsin F (C01 family) 0.0138 0.0203 0.0203
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0386 0.0645 1
Entamoeba histolytica heat shock protein 90, putative 0.0142 0.0211 0.4361
Schistosoma mansoni voltage-gated cation channel 0.0107 0.0149 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0029 0.0009 0.0008
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0022 0.006
Leishmania major calcium channel protein, putative,ion transporter, putative 0.1662 0.2915 1
Giardia lamblia Hypothetical protein 0.0029 0.0009 0.0005
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0071 0.036
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.016 0.0243 0.0243
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0203 0.8355
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0029 0.0009 0.0005
Giardia lamblia Cathepsin L precursor 0.0029 0.0009 0.0005
Loa Loa (eye worm) calcium channel 0.0107 0.0149 0.0778
Schistosoma mansoni hypothetical protein 0.0041 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0005 0.0001
Onchocerca volvulus 0.0138 0.0203 0.2678
Giardia lamblia Dipeptidyl-peptidase I precursor 0.2159 0.38 0.3797
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0084 0.0107 0.0354
Plasmodium falciparum serine repeat antigen 7 0.0029 0.0009 0.0006
Brugia malayi kinase, mitochondrial precursor 0.0026 0.0005 0.0013
Echinococcus multilocularis endoplasmin 0.012 0.0171 0.0572
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.5644 1 1
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0071 0.0071
Echinococcus multilocularis ryanodine receptor 44f 0.0107 0.0149 0.0498
Plasmodium falciparum heat shock protein 90, putative 0.0066 0.0076 0.0073
Entamoeba histolytica cysteine protease, putative 0.0029 0.0009 0.0101
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Trypanosoma cruzi DNA topoisomerase II, putative 0.0026 0.0005 0.0076
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0029 0.0009 0.0101
Schistosoma mansoni heat shock protein 0.0142 0.0211 0.0211
Mycobacterium ulcerans methionine aminopeptidase MapB 0.0034 0.0018 0.014
Giardia lamblia Cysteine protease 0.0029 0.0009 0.0005
Schistosoma mansoni survival motor neuron protein 0.0048 0.0044 0.0044
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0069 0.0081 0.3274
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0107 0.0149 0.0149
Echinococcus multilocularis transient receptor potential gamma protein 0.0107 0.0149 0.0498
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0009 0.0036
Brugia malayi Steroid receptor seven-up type 2 0.0038 0.0026 0.0123
Brugia malayi MH2 domain containing protein 0.0119 0.017 0.0892
Onchocerca volvulus Methionine aminopeptidase 2 homolog 0.0047 0.0042 0.0502
Echinococcus multilocularis calcium activated potassium channel 0.0107 0.0149 0.0498
Echinococcus multilocularis expressed conserved protein 0.0092 0.0123 0.0406
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0107 0.0149 0.0498
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0107 0.0149 0.0498
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0026 0.0005 0.0088
Loa Loa (eye worm) hypothetical protein 0.0108 0.015 0.0779
Brugia malayi O-methyltransferase family protein 0.006 0.0065 0.0331
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.018
Plasmodium vivax unspecified product 0.0073 0.0088 0.0085
Plasmodium falciparum serine repeat antigen 9 0.0029 0.0009 0.0006
Trypanosoma cruzi heat shock protein 90, putative 0.0076 0.0093 0.3772
Trypanosoma brucei Metacaspase-4 0.0027 0.0005 0.0114
Entamoeba histolytica cysteine proteinase, putative 0.0073 0.0088 0.1762
Brugia malayi initiation factor 2-associated protein. 0.0047 0.0042 0.021
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0047 0.0042 0.1629
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0009 0.0008
Brugia malayi ion channel NompC 0.0107 0.0149 0.078
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0026 0.0075
Brugia malayi Bromodomain containing protein 0.0075 0.0092 0.0473
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0112 0.0539
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0038 0.0026 0.0072
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0005 0.0013
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0076 0.0076
Toxoplasma gondii methionine aminopeptidase 0.0034 0.0018 0.0016
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0005 0.001
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0107 0.0149 0.0498
Loa Loa (eye worm) hypothetical protein 0.0236 0.0379 0.1995
Trypanosoma cruzi major cysteine proteinase, putative 0.0029 0.0009 0.0262
Giardia lamblia Proteasome subunit beta type 5 precursor 0.007 0.0083 0.0078
Entamoeba histolytica 90 kDa heat shock protein, putative 0.007 0.0082 0.1648
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0034 0.0018 0.0018
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0005 0.001
Trypanosoma brucei Heat shock protein 83, putative 0.0142 0.0211 1
Plasmodium falciparum heat shock protein 90 0.0142 0.0211 0.0208
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0013 0.0058
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0076 0.3028
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0029 0.0009 0.0101
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0026 0.0005 0.0001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0029 0.0009 0.0009
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0004 0.0005
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0005 0.001
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0071 0.0363
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0203 0.963
Trypanosoma cruzi cysteine protease, putative 0.0073 0.0088 0.3543
Onchocerca volvulus 0.0038 0.0026 0.028
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0107 0.0149 0.0149
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3109 0.5489 0.9172
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.007 0.0083 0.0126
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0038 0.0026 0.0026
Schistosoma mansoni cathepsin C 0.0029 0.0009 0.0009
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0107 0.0149 0.0149
Echinococcus granulosus transient receptor potential cation channel 0.0107 0.0149 0.0498
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0138 0.0203 0.0683
Loa Loa (eye worm) hypothetical protein 0.0071 0.0084 0.043
Toxoplasma gondii cathepsin CPL 0.0138 0.0203 0.02
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0047 0.0042 0.0061
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0203 0.963
Echinococcus granulosus potassium large conductance calcium activated 0.0107 0.0149 0.0498
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0071 0.0071
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0005 0.0001
Schistosoma mansoni o-methyltransferase 0.006 0.0065 0.0065
Giardia lamblia Cathepsin B precursor 0.0029 0.0009 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0088 0.0134
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0112 0.0179
Loa Loa (eye worm) endoplasmin 0.0142 0.0211 0.1104
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.012
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0107 0.0149 0.0498
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0038 0.0026 0.012
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.012 0.0171 0.0278
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0026 0.0005 0.0013
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.005 0.0048 0.1872
Loa Loa (eye worm) hypothetical protein 0.0043 0.0034 0.0165
Schistosoma mansoni hypothetical protein 0.1083 0.1886 0.1886
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0034 0.0018 0.0048
Plasmodium falciparum heat shock protein 90, putative 0.0213 0.0337 0.0334
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0107 0.0149 0.0498
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Echinococcus multilocularis hyperpolarization activated cyclic 0.0107 0.0149 0.0498
Loa Loa (eye worm) heat shock protein 90 0.0142 0.0211 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0005 0.0001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0029 0.0009 0.0009
Trypanosoma brucei metallo- peptidase, Clan MG, Family M24 0.005 0.0048 0.2158
Trypanosoma cruzi metacaspase 5, putative 0.0027 0.0005 0.0099
Giardia lamblia Grp94/Hsp90 0.012 0.0171 0.0167
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.0129 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0033 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0203 0.963
Plasmodium vivax SET domain protein, putative 0.003 0.0011 0.0008
Onchocerca volvulus 0.0066 0.0075 0.0953
Plasmodium falciparum serine repeat antigen 6 0.0029 0.0009 0.0006
Plasmodium vivax heat shock protein, putative 0.0213 0.0337 0.0334
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Giardia lamblia Cathepsin B precursor 0.0029 0.0009 0.0005
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0138 0.0203 0.02
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0107 0.0149 0.0498
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0038 0.0026 0.0072
Brugia malayi fibroinase precursor 0.0029 0.0009 0.0036
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0089 0.0291
Echinococcus granulosus Niemann Pick C1 protein 0.0141 0.0208 0.0701
Toxoplasma gondii hypothetical protein 0.0107 0.0149 0.0146
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0478 0.0763
Trypanosoma brucei trypanothione reductase 0.0038 0.0025 0.1079
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0108 0.015 0.2267
Entamoeba histolytica cysteine protease, putative 0.0029 0.0009 0.0101
Echinococcus granulosus transient receptor potential cation channel 0.0107 0.0149 0.0498
Echinococcus multilocularis hyperpolarization activated cyclic 0.0107 0.0149 0.0498
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0066 0.0335
Echinococcus granulosus transient receptor potential cation channel 0.0107 0.0149 0.0498
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0107 0.0149 0.078
Entamoeba histolytica cysteine protease, putative 0.0029 0.0009 0.0101
Echinococcus multilocularis cathepsin b 0.016 0.0243 0.0818
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.012 0.0171 0.2595
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Echinococcus multilocularis transfer RNA-Gly 0.0107 0.0149 0.0498
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.016 0.0243 0.0243
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0026 0.0005 0.0013
Trypanosoma brucei heat shock protein, putative 0.0142 0.0211 1
Mycobacterium tuberculosis Probable catechol-O-methyltransferase 0.0517 0.0878 0.1461
Plasmodium falciparum serine repeat antigen 8 0.0029 0.0009 0.0006
Echinococcus multilocularis two pore calcium channel protein 1 0.0107 0.0149 0.0498
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0044 0.0037 0.018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0038 0.0026 0.0123
Brugia malayi Flap endonuclease-1 0.0026 0.0004 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0009 0.0008
Toxoplasma gondii heat shock protein 90, putative 0.0142 0.0211 0.0208
Echinococcus multilocularis cysteine protease 0.0138 0.0203 0.0683
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0088 0.4084
Trichomonas vaginalis DNA topoisomerase II, putative 0.0026 0.0005 0.0001
Echinococcus granulosus heat shock protein 90 0.0116 0.0164 0.0549
Schistosoma mansoni cathepsin s 0.0044 0.0037 0.0037
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0107 0.0149 0.0778
Schistosoma mansoni transient receptor potential channel 0.0107 0.0149 0.0149
Onchocerca volvulus Huntingtin homolog 0.0122 0.0176 0.231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Echinococcus multilocularis transient receptor potential cation channel 0.0107 0.0149 0.0498
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Plasmodium vivax proteasome subunit beta type-5, putative 0.007 0.0083 0.008
Echinococcus granulosus FTZ F1 alpha 0.0038 0.0026 0.0072
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.0124
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0061 0.0312
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0038 0.0026 0.012
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0029 0.0009 0.0009
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0029 0.0009 0.0006
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0029 0.0009 0.0006
Echinococcus granulosus ryanodine receptor 44f 0.0107 0.0149 0.0498
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0107 0.0149 0.0778
Schistosoma mansoni vesicular amine transporter 0.0107 0.0149 0.0149
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.007 0.0083 0.3325
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0107 0.0149 0.078
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0026 0.0005 0.0076
Schistosoma mansoni bromodomain containing protein 0.0063 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Echinococcus multilocularis Protein lozenge 0.0056 0.0057 0.018
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Entamoeba histolytica cysteine proteinase, putative 0.0073 0.0088 0.1762
Brugia malayi Cathepsin L-like precursor 0.0138 0.0203 0.1066
Echinococcus multilocularis heat shock protein 90 0.0116 0.0164 0.0549
Onchocerca volvulus Cathepsin L homolog 0.0029 0.0009 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0026 0.0026
Brugia malayi O-methyltransferase family protein 0.006 0.0065 0.0331
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0061 0.0309
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.007 0.0083 0.0083
Leishmania major cathepsin L-like protease 0.0138 0.0203 0.0688
Brugia malayi cation channel family protein 0.0107 0.0149 0.078
Echinococcus granulosus cathepsin L cysteine protease 0.0073 0.0088 0.0287
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0029 0.0009 0.0033
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.1083 0.1886 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0026 0.0005 0.0002
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0038 0.0026 0.0026
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0025 0.0936
Loa Loa (eye worm) hypothetical protein 0.006 0.0065 0.0328
Brugia malayi RNA binding protein 0.0063 0.0071 0.0363
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Plasmodium vivax methionine aminopeptidase 2, putative 0.0047 0.0042 0.0039
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0076 0.0244
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Brugia malayi hypothetical protein 0.0025 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0036 0.0022 0.0373
Leishmania major developmentally regulated phosphoprotein-like protein 0.0026 0.0005 0.0006
Brugia malayi cathepsin F-like cysteine proteinase 0.0044 0.0037 0.0182
Trypanosoma brucei heat shock protein, putative 0.0142 0.0211 1
Trypanosoma cruzi heat shock protein 90, putative 0.0116 0.0164 0.673
Mycobacterium ulcerans heat shock protein 90 0.012 0.0171 0.1696
Giardia lamblia Heat shock protein HSP 90-alpha 0.0142 0.0211 0.0207
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.0133 0.0442
Onchocerca volvulus 0.0138 0.0203 0.2678
Toxoplasma gondii heat shock protein 75, putative 0.007 0.0082 0.008
Leishmania major cathepsin L-like protease 0.0138 0.0203 0.0688
Loa Loa (eye worm) cysteine protease 0.0138 0.0203 0.1064
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.0478 1
Schistosoma mansoni endoplasmin 0.0142 0.0211 0.0211
Wolbachia endosymbiont of Brugia malayi methionine aminopeptidase 0.0034 0.0018 0.0214
Schistosoma mansoni pyruvate dehydrogenase 0.0026 0.0005 0.0005
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0107 0.0149 0.0498
Schistosoma mansoni methionyl aminopeptidase 2 (M24 family) 0.0047 0.0042 0.0042
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.0212 0.1047
Schistosoma mansoni transient receptor potential channel 0.0107 0.0149 0.0149
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0047 0.0042 0.1629
Schistosoma mansoni Replicative DNA helicase 0.0386 0.0645 0.0645
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.012
Toxoplasma gondii DNA topoisomerase 2, putative 0.0026 0.0005 0.0002
Schistosoma mansoni o-methyltransferase 0.006 0.0065 0.0065
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0107 0.0149 0.0498
Brugia malayi Pre-SET motif family protein 0.003 0.0011 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0009 0.0008
Entamoeba histolytica heat shock protein 90, putative 0.0142 0.0211 0.4361
Brugia malayi Cathepsin L-like precursor 0.0094 0.0125 0.0649
Echinococcus multilocularis two pore calcium channel protein 2 0.0107 0.0149 0.0498
Onchocerca volvulus 0.0026 0.0005 0.0001
Loa Loa (eye worm) DEAH box polypeptide 35 0.0064 0.0072 0.0364
Schistosoma mansoni hypothetical protein 0.0107 0.0149 0.0149
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0005 0.0001
Brugia malayi Pre-SET motif family protein 0.0208 0.0328 0.173
Echinococcus multilocularis transient receptor potential cation channel 0.0107 0.0149 0.0498
Echinococcus multilocularis heat shock protein 0.0142 0.0211 0.0709
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0047 0.0042 0.0061
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0107 0.0149 0.0149
Onchocerca volvulus Cathepsin F homolog 0.0138 0.0203 0.2678
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.012 0.0171 0.0577
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0138 0.0203 0.032
Trypanosoma brucei metacaspase 0.0027 0.0005 0.0114
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0107 0.0149 0.0498
Trypanosoma cruzi metacaspase, putative 0.0027 0.0005 0.0099
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0203 0.8355
Toxoplasma gondii transporter, cation channel family protein 0.0107 0.0149 0.0146
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0038 0.0026 0.0026
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0112 0.0179
Brugia malayi Cathepsin L-like precursor 0.0138 0.0203 0.1066
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0019 0.0087
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0005 0.0001
Echinococcus multilocularis short transient receptor potential channel 6 0.0107 0.0149 0.0498
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0026 0.0005 0.0002
Plasmodium vivax methionine aminopeptidase 1a, putative 0.0034 0.0018 0.0016
Onchocerca volvulus 0.0138 0.0203 0.2678
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.007 0.0083 0.1652
Echinococcus multilocularis methionyl aminopeptidase 2 0.0047 0.0042 0.0129
Schistosoma mansoni o-methyltransferase 0.006 0.0065 0.0065
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0107 0.0149 0.0149
Giardia lamblia Hypothetical protein 0.0029 0.0009 0.0005
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0107 0.0149 0.0498
Echinococcus multilocularis shaker cognate 0.0107 0.0149 0.0498
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0038 0.0026 0.0072
Entamoeba histolytica cysteine proteinase, putative 0.0094 0.0125 0.2537
Plasmodium vivax vivapain-1 0.0073 0.0088 0.0085
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Brugia malayi Cathepsin L-like precursor 0.0138 0.0203 0.1066
Brugia malayi cathepsin L-like precursor 0.0094 0.0125 0.0649
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0107 0.0149 0.0498
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0038 0.0026 0.0123
Entamoeba histolytica cysteine protease, putative 0.0029 0.0009 0.0101
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0005 0.0002
Echinococcus granulosus potassium voltage gated channel protein 0.0107 0.0149 0.0498
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0005 0.0002
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0033 0.0161
Onchocerca volvulus 0.0138 0.0203 0.2678
Echinococcus granulosus cysteine protease 0.0073 0.0088 0.0287
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0088 0.0454
Echinococcus multilocularis thyroid hormone receptor alpha 0.0038 0.0026 0.0072
Schistosoma mansoni calcium-activated potassium channel 0.0107 0.0149 0.0149
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0073 0.0088 0.0088
Giardia lamblia Cysteine protease 0.0029 0.0009 0.0005
Toxoplasma gondii preprocathepsin c precursor, putative 0.5644 1 1
Giardia lamblia Cathepsin B precursor 0.0069 0.0081 0.0077
Loa Loa (eye worm) runx1 0.0056 0.0057 0.0287
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0033
Brugia malayi Cathepsin L-like cysteine proteinase 0.0094 0.0125 0.0649
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0107 0.0149 0.078
Brugia malayi Probable DNA topoisomerase II 0.0026 0.0005 0.0013
Schistosoma mansoni thyroid hormone receptor 0.0038 0.0026 0.0026
Entamoeba histolytica hypothetical protein 0.0029 0.0009 0.0101
Giardia lamblia Cathepsin B precursor 0.0029 0.0009 0.0005
Leishmania major DNA topoisomerase ii 0.0026 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0098 0.0133 0.0692
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0088 0.4084
Onchocerca volvulus 0.0237 0.038 0.5058
Echinococcus granulosus ecdysone induced protein 78C 0.0038 0.0026 0.0072
Trypanosoma brucei methionine aminopeptidase, putative 0.005 0.0048 0.2158
Leishmania major cathepsin L-like protease 0.0138 0.0203 0.0688
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0478 0.0763
Entamoeba histolytica cysteine proteinase, putative 0.0138 0.0203 0.4198
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0004 0.0062
Schistosoma mansoni patched 1 0.0042 0.0033 0.0033
Echinococcus granulosus potassium voltage gated channel protein 0.0107 0.0149 0.0498
Giardia lamblia Cathepsin B precursor 0.0069 0.0081 0.0077
Schistosoma mansoni hypothetical protein 0.0052 0.005 0.005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0011 0.0011
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0107 0.0149 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0038 0.0026 0.0123
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.0133 0.272
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0107 0.0149 0.078
Trypanosoma brucei metacaspase MCA3 0.0027 0.0005 0.0114
Schistosoma mansoni peroxidasin 0.0026 0.0005 0.0005
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0138 0.0203 0.0683
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0107 0.0149 0.7043
Giardia lamblia Fructose-bisphosphate aldolase 0.0292 0.0478 0.0474
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0038 0.0026 0.0072
Trichomonas vaginalis set domain proteins, putative 0.0237 0.0379 0.0604
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0029 0.0009 0.0008
Toxoplasma gondii cathepsin CPC1 0.5644 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Loa Loa (eye worm) hypothetical protein 0.0577 0.0985 0.5217
Onchocerca volvulus 0.0026 0.0005 0.0001
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0107 0.0149 0.0498
Toxoplasma gondii thioredoxin reductase 0.0038 0.0025 0.0022
Trypanosoma cruzi cysteine proteinase, putative 0.0073 0.0088 0.3543
Schistosoma mansoni cathepsin B (C01 family) 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.007 0.0082 0.1048
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0107 0.0149 0.0498
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Schistosoma mansoni hypothetical protein 0.0041 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0138 0.0203 0.1064
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0107 0.0149 0.0149
Trypanosoma brucei developmentally regulated phosphoprotein 0.0026 0.0005 0.0088
Echinococcus granulosus potassium voltage gated channel protein 0.0107 0.0149 0.0498
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0107 0.0149 0.0498
Echinococcus multilocularis transient receptor potential cation channel 0.0107 0.0149 0.0498
Echinococcus granulosus short transient receptor potential channel 6 0.0107 0.0149 0.0498
Onchocerca volvulus Cell death protein 3 homolog 0.0027 0.0005 0.0007
Plasmodium vivax DNA gyrase subunit B, putative 0.0026 0.0005 0.0002
Echinococcus multilocularis sodium leak channel non selective protein 0.0107 0.0149 0.0498
Leishmania major trypanothione reductase 0.0038 0.0025 0.0077
Onchocerca volvulus 0.0029 0.0009 0.006
Echinococcus multilocularis proteasome (prosome, macropain) 0.007 0.0083 0.0269
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Toxoplasma gondii cathepsin CPC2 0.2159 0.38 0.3798
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.0379 0.1286
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Wolbachia endosymbiont of Brugia malayi O-methyltransferase 0.006 0.0065 0.0936
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0034 0.0018 0.0018
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.018
Mycobacterium ulcerans proteasome PrcB 0.007 0.0083 0.0794
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0009 0.0008
Onchocerca volvulus Peroxidase homolog 0.0026 0.0005 0.0001
Trypanosoma brucei heat shock protein, putative 0.0142 0.0211 1
Giardia lamblia Cathepsin L-like protease 0.0029 0.0009 0.0005
Echinococcus multilocularis voltage dependent calcium channel 0.0107 0.0149 0.0498
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0029 0.0009 0.0033
Echinococcus multilocularis cathepsin L cysteine protease 0.0138 0.0203 0.0683
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0038 0.0026 0.0072
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0026 0.0005 0.0002
Trypanosoma brucei cysteine peptidase C (CPC) 0.0069 0.0081 0.3774
Plasmodium falciparum serine repeat antigen 4 0.0029 0.0009 0.0006
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0005 0.0001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0107 0.0149 0.0146
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0041 0.0031 0.0147
Trypanosoma brucei proteasome subunit beta type-5, putative 0.007 0.0083 0.3832
Onchocerca volvulus Bile acid receptor homolog 0.0038 0.0026 0.028
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0094 0.0125 0.5074
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0107 0.0149 0.0498
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0005 0.0001
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0107 0.0149 0.078
Trypanosoma cruzi Heat shock protein 83, putative 0.0142 0.0211 0.8676
Echinococcus multilocularis voltage dependent calcium channel 0.0107 0.0149 0.0498
Brugia malayi indoleamine 2,3-dioxygenase 0.1083 0.1886 1
Brugia malayi Cathepsin L-like precursor 0.0138 0.0203 0.1066
Onchocerca volvulus 0.003 0.0011 0.0087
Leishmania major hypothetical protein, unknown function 0.0107 0.0149 0.0503
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0107 0.0149 0.611
Brugia malayi hypothetical protein 0.0066 0.0075 0.0387
Echinococcus granulosus cathepsin l1 0.0094 0.0125 0.0413
Loa Loa (eye worm) hypothetical protein 0.0082 0.0103 0.0533
Trichomonas vaginalis heat shock protein, putative 0.0066 0.0076 0.0115
Loa Loa (eye worm) cathepsin B 0.0069 0.0081 0.0417
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0203 0.963
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0026 0.0005 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.0026 0.0123
Echinococcus multilocularis protein dispatched 1 0.0048 0.0044 0.0136
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0073 0.0088 0.3543
Echinococcus granulosus expressed conserved protein 0.0092 0.0123 0.0406
Brugia malayi Cathepsin L-like precursor 0.0094 0.0125 0.0649
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0061 0.0309
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0107 0.0149 0.0149
Schistosoma mansoni peroxidasin 0.0026 0.0005 0.0005
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0107 0.0149 0.1952
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0038 0.0026 0.0123
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0026 0.0072
Echinococcus multilocularis cysteine protease 0.0138 0.0203 0.0683
Mycobacterium leprae proteasome (beta subunit) PrcB 0.007 0.0083 0.0393
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0005 0.0001
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0107 0.0149 0.0498
Leishmania major cathepsin L-like protease 0.0138 0.0203 0.0688
Echinococcus granulosus hyperpolarization activated cyclic 0.0107 0.0149 0.0498
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0138 0.0203 0.032
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.1083 0.1886 0.6464
Schistosoma mansoni caspase-3 (C14 family) 0.0027 0.0005 0.0005
Trypanosoma cruzi heat shock protein 85, putative 0.0116 0.0164 0.673
Echinococcus granulosus voltage dependent calcium channel 0.0107 0.0149 0.0498
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0033 0.0099
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0047 0.0042 0.0061
Plasmodium vivax unspecified product 0.0044 0.0037 0.0034
Leishmania major hypothetical protein, conserved 0.0026 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Schistosoma mansoni lozenge 0.0056 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0107 0.0149 0.0498
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0138 0.0203 0.032
Giardia lamblia Methionine aminopeptidase 0.0047 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0013
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0026 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Onchocerca volvulus 0.006 0.0065 0.0809
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0107 0.0149 0.078
Trichomonas vaginalis heat shock protein, putative 0.012 0.0171 0.0268
Plasmodium vivax heat shock protein 86, putative 0.0142 0.0211 0.0208
Plasmodium falciparum serine repeat antigen 3 0.0029 0.0009 0.0006
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.016 0.0243 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0033 0.0161
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Echinococcus granulosus short transient receptor potential channel 6 0.0108 0.015 0.0499
Schistosoma mansoni 60S ribosomal protein L21 0.0107 0.0149 0.0149
Echinococcus multilocularis microtubule associated protein 2 0.1481 0.2593 0.8895
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0026 0.0074
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) 0.0034 0.0018 0.0069
Echinococcus multilocularis geminin 0.0169 0.0259 0.0876
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0076 0.1501
Toxoplasma gondii transporter, cation channel family protein 0.0107 0.0149 0.0146
Trypanosoma brucei heat shock protein, putative 0.0142 0.0211 1
Giardia lamblia Cathepsin B precursor 0.0029 0.0009 0.0005
Echinococcus multilocularis lamin dm0 0.0058 0.0061 0.0195
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0009 0.0008
Trypanosoma cruzi cysteine proteinase, putative 0.0073 0.0088 0.3543
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0005 0.0002
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0076 0.3028
Giardia lamblia Heat shock protein HSP 90-alpha 0.0116 0.0164 0.016
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0027 0.0005 0.0003
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0044 0.022
Trypanosoma cruzi cruzipain precursor, putative 0.0138 0.0203 0.8355
Echinococcus granulosus cathepsin b 0.016 0.0243 0.0818
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0009 0.0008
Schistosoma mansoni cathepsin F (C01 family) 0.0138 0.0203 0.0203
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0042 0.0042
Onchocerca volvulus 0.0138 0.0203 0.2678
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0033
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0013 0.0055
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0047 0.0042 0.1877
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0112 0.0179
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0038 0.0026 0.0072
Plasmodium vivax glutathione reductase, putative 0.0038 0.0025 0.0022
Trichomonas vaginalis receptor histidine kinase, putative 0.0026 0.0005 0.0001
Schistosoma mansoni lamin 0.0058 0.0061 0.0061
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.0037 0.1411
Echinococcus multilocularis heat shock protein 90 0.0142 0.0211 0.0709
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.0125 0.0194
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Echinococcus granulosus shaker cognate 0.0107 0.0149 0.0498
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0112 0.0179
Echinococcus multilocularis potassium voltage gated channel protein 0.0107 0.0149 0.0498
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0022 0.006
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.017 0.0889
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.5644 1 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Trichomonas vaginalis heat shock protein, putative 0.0092 0.0122 0.019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0203 0.963
Giardia lamblia Cysteine protease 0.0029 0.0009 0.0005
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0203 0.8355
Trichomonas vaginalis endoplasmin, putative 0.0092 0.0122 0.019
Echinococcus multilocularis jun protein 0.0084 0.0107 0.0354
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0064 0.0206
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0107 0.0149 0.0498
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Echinococcus multilocularis voltage gated potassium channel 0.0107 0.0149 0.0498
Schistosoma mansoni caspase-7 (C14 family) 0.0027 0.0005 0.0005
Schistosoma mansoni caspase-7 (C14 family) 0.0027 0.0005 0.0005
Brugia malayi Cell death protein 3 precursor 0.0027 0.0005 0.0015
Trichomonas vaginalis heat shock protein, putative 0.012 0.0171 0.0268
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) 0.0034 0.0018 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0038 0.0026 0.0123
Giardia lamblia Cathepsin L precursor 0.0029 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.015 0.0499
Mycobacterium leprae Conserved hypothetical protein 0.1139 0.1984 1
Toxoplasma gondii methionine aminopeptidase 2, putative 0.0047 0.0042 0.0039
Echinococcus granulosus potassium voltage gated channel protein 0.0107 0.0149 0.0498
Plasmodium falciparum cysteine proteinase falcipain 3 0.0138 0.0203 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0029 0.0009 0.0008
Echinococcus granulosus sodium leak channel non selective protein 0.0107 0.0149 0.0498
Brugia malayi nuclear receptor NHR-88 0.0038 0.0026 0.0123
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0009 0.0008
Echinococcus granulosus cathepsin l1 0.0138 0.0203 0.0683
Brugia malayi cathepsin B-like cysteine proteinase 0.016 0.0243 0.1275
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0025 0.0119
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0011 0.0023
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.0478 1
Entamoeba histolytica cysteine proteinase 2 0.0073 0.0088 0.1762
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.0026 0.0123
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0138 0.0203 0.1064
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.3513 0.6209 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0047 0.0233
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.0036 0.0022 0.0022
Schistosoma mansoni coup transcription factor 0.0038 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0029 0.0009 0.0006
Plasmodium vivax metacaspase 1, putative 0.0027 0.0005 0.0002
Onchocerca volvulus 0.0048 0.0044 0.0528
Brugia malayi cathepsin L precursor 0.0029 0.0009 0.0036
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Brugia malayi glutathione reductase 0.0038 0.0025 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0203 0.963
Brugia malayi cation channel family protein 0.0107 0.0149 0.078
Echinococcus granulosus intermediate filament protein 0.0058 0.0061 0.0195
Giardia lamblia Cathepsin L precursor 0.0029 0.0009 0.0005
Leishmania major cathepsin L-like protease 0.0138 0.0203 0.0688
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0107 0.0149 0.0498
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0005 0.001
Brugia malayi Papain family cysteine protease containing protein 0.0138 0.0203 0.1066
Echinococcus granulosus jun protein 0.0084 0.0107 0.0354
Entamoeba histolytica cysteine proteinase 1, putative 0.0073 0.0088 0.1762
Schistosoma mansoni intermediate filament proteins 0.0058 0.0061 0.0061
Schistosoma mansoni endoplasmin 0.0142 0.0211 0.0211
Brugia malayi Bromodomain containing protein 0.0038 0.0026 0.0126
Echinococcus multilocularis caspase 8 0.0027 0.0005 0.0003
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0107 0.0149 0.078
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0107 0.0149 0.078
Onchocerca volvulus 0.0138 0.0203 0.2678
Echinococcus granulosus calcium activated potassium channel 0.0107 0.0149 0.0498
Loa Loa (eye worm) hypothetical protein 0.0443 0.0746 0.3945
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0026 0.0005 0.0002
Echinococcus multilocularis voltage gated potassium channel 0.0107 0.0149 0.0498
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.0212 0.0347
Echinococcus multilocularis ecdysone induced protein 78C 0.0038 0.0026 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0005 0.0001
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.3387 0.5985 1
Brugia malayi hypothetical protein 0.0026 0.0005 0.0013
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Echinococcus multilocularis FTZ F1 alpha 0.0038 0.0026 0.0072
Leishmania major proteasome beta 5 subunit, putative 0.007 0.0083 0.0274
Brugia malayi O-methyltransferase 0.006 0.0065 0.0331
Mycobacterium tuberculosis Probable methyltransferase 0.006 0.0065 0.01
Schistosoma mansoni RAR-like nuclear receptor 0.0038 0.0026 0.0026
Loa Loa (eye worm) fibroinase 0.0138 0.0203 0.1064
Brugia malayi Cathepsin L-like precursor 0.0138 0.0203 0.1066
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Onchocerca volvulus 0.006 0.0065 0.0809
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0107 0.0149 0.078
Loa Loa (eye worm) voltage-dependent calcium channel 0.0107 0.0149 0.0778
Mycobacterium ulcerans recombinase A 0.0108 0.015 0.1482
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0478 0.0763
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0107 0.0149 0.0498
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Echinococcus granulosus geminin 0.0169 0.0259 0.0876
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Brugia malayi Peroxidasin 0.0026 0.0005 0.0013
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Echinococcus granulosus hyperpolarization activated cyclic 0.0107 0.0149 0.0498
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0107 0.0149 0.0149
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0026 0.0005 0.0076
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0107 0.0149 0.078
Trichomonas vaginalis heat shock protein, putative 0.0116 0.0164 0.0258
Echinococcus granulosus sodium channel protein 0.1662 0.2915 1
Trypanosoma cruzi heat shock protein 90, putative 0.0142 0.0211 0.8676
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Treponema pallidum fructose-bisphosphate aldolase 0.0292 0.0478 0.7386
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.005 0.0048 0.0149
Giardia lamblia Encystation-specific protease 0.2159 0.38 0.3797
Schistosoma mansoni retinoic acid receptor RXR 0.0038 0.0026 0.0026
Trypanosoma brucei DNA topoisomerase ii 0.0026 0.0005 0.0088
Plasmodium falciparum proteasome subunit beta type-5 0.007 0.0083 0.008
Schistosoma mansoni hypothetical protein 0.0034 0.0019 0.0019
Echinococcus granulosus two pore calcium channel protein 1 0.0107 0.0149 0.0498
Mycobacterium ulcerans methionine aminopeptidase 0.0034 0.0018 0.014
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Trypanosoma brucei methionine aminopeptidase, type I, putative 0.005 0.0048 0.2158
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0107 0.0149 0.7043
Schistosoma mansoni voltage-dependent calcium channel 0.0107 0.0149 0.0149
Schistosoma mansoni two-pore calcium channel 0.0107 0.0149 0.0149
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Plasmodium falciparum methionine aminopeptidase 1a, putative 0.0034 0.0018 0.0016
Mycobacterium leprae PROBABLE METHYLTRANSFERASE 0.006 0.0065 0.0303
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0112 0.0179
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0038 0.0026 0.0026
Loa Loa (eye worm) ctsf protein 0.0138 0.0203 0.1064
Trypanosoma cruzi heat shock protein, putative 0.007 0.0082 0.3317
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0138 0.0203 0.032
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0029 0.0009 0.0009
Echinococcus granulosus transient receptor potential cation channel 0.0107 0.0149 0.0498
Echinococcus multilocularis lamin 0.0058 0.0061 0.0195
Echinococcus granulosus transient receptor potential cation channel 0.0107 0.0149 0.0498
Entamoeba histolytica cysteine protease, putative 0.0029 0.0009 0.0101
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0025 0.0022
Plasmodium falciparum serine repeat antigen 5 0.0029 0.0009 0.0006
Mycobacterium tuberculosis Probable reductase 0.0086 0.0112 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.0026 0.0123
Trypanosoma brucei heat shock protein 90, putative 0.0142 0.0211 1
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0027 0.0005 0.0005
Trypanosoma cruzi heat shock protein 85, putative 0.0142 0.0211 0.8676
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0025 0.0034
Chlamydia trachomatis replicative DNA helicase 0.0386 0.0645 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0107 0.0149 0.0149
Brugia malayi small heat shock protein 0.0577 0.0985 0.5219
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.0136 0.0136
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.0133 0.0694
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0138 0.0203 0.1064
Echinococcus multilocularis potassium voltage gated channel protein 0.0107 0.0149 0.0498
Entamoeba histolytica hypothetical protein 0.0036 0.0022 0.0373
Plasmodium falciparum methionine aminopeptidase 2 0.0047 0.0042 0.0039
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0029 0.0009 0.0036
Brugia malayi nuclear hormone receptor 0.0038 0.0026 0.0123
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.015 0.0499
Echinococcus granulosus voltage gated potassium channel 0.0107 0.0149 0.0498
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0107 0.0149 0.0149
Echinococcus granulosus heat shock protein 0.0142 0.0211 0.0709
Trypanosoma brucei metacaspase MCA2 0.0027 0.0005 0.0114
Toxoplasma gondii methionine aminopeptidase 0.005 0.0048 0.0045
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0107 0.0149 0.0778
Brugia malayi Cyclic-nucleotide gated cation channel 0.0107 0.0149 0.078
Onchocerca volvulus 0.0058 0.0061 0.076
Brugia malayi ecdysteroid receptor 0.0038 0.0026 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0005 0.0001
Loa Loa (eye worm) ryanodine receptor 0.0107 0.0149 0.0778
Plasmodium falciparum endoplasmin, putative 0.0092 0.0122 0.0119
Schistosoma mansoni ryanodine receptor related 0.0107 0.0149 0.0149
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.017 0.0889
Toxoplasma gondii transporter, cation channel family protein 0.0107 0.0149 0.0146
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0005 0.0001
Brugia malayi steroid hormone receptor 0.0038 0.0026 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0029 0.0009 0.0008
Brugia malayi Thioredoxin reductase 0.0038 0.0025 0.0122
Onchocerca volvulus 0.0443 0.0746 1
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0107 0.0149 0.078
Echinococcus granulosus cathepsin L 0.0073 0.0088 0.0287
Loa Loa (eye worm) hypothetical protein 0.0052 0.005 0.0251
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.007 0.0083 0.013
Entamoeba histolytica DNA topoisomerase II, putative 0.0026 0.0005 0.0007
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0008 0.0012
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0026 0.0005 0.0001
Treponema pallidum heat shock protein 90 0.012 0.0171 0.2595
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0033 0.0017 0.0685
Giardia lamblia Cathepsin L precursor 0.0029 0.0009 0.0005
Schistosoma mansoni heat shock protein 0.007 0.0082 0.0082
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.1662 0.2915 1
Toxoplasma gondii cathepsin B 0.0069 0.0081 0.0078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0138 0.0203 0.032
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0038 0.0026 0.012
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.007 0.0082 0.0268
Echinococcus multilocularis peroxidasin 0.0026 0.0005 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.015 0.0499
Brugia malayi Cathepsin L-like precursor 0.0044 0.0037 0.0182
Entamoeba histolytica cysteine protease, putative 0.0029 0.0009 0.0101
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0026 0.0072
Trichomonas vaginalis receptor histidine kinase, putative 0.0026 0.0005 0.0001
Echinococcus multilocularis cathepsin L 0.0029 0.0009 0.0016
Brugia malayi TAR-binding protein 0.0063 0.0071 0.0363
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.016 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.012
Leishmania major metacaspase, putative 0.0027 0.0005 0.0008
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0108 0.015 0.0734
Brugia malayi jmjC domain containing protein 0.0061 0.0066 0.0338
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Leishmania major methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 0.005 0.0048 0.0154
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0026 0.0005 0.0001
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0029 0.0009 0.0009
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0116 0.0164 0.0549
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0038 0.0026 0.0026
Echinococcus granulosus proteasome prosome macropain 0.007 0.0083 0.0269
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0386 0.0645 0.6534
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0107 0.0149 0.0498
Echinococcus granulosus cathepsin L 0.0029 0.0009 0.0016
Schistosoma mansoni cathepsin S (C01 family) 0.0029 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0203 0.963
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0038 0.0026 0.0072
Echinococcus granulosus hypothetical protein 0.0107 0.0149 0.0498
Plasmodium falciparum DNA gyrase subunit B 0.0026 0.0005 0.0002
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.005 0.0048 0.1872
Onchocerca volvulus Cathepsin L homolog 0.0138 0.0203 0.2678
Brugia malayi voltage-dependent calcium channel 0.0107 0.0149 0.078
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0038 0.0026 0.0072
Echinococcus multilocularis conserved hypothetical protein 0.0107 0.0149 0.0498
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0107 0.0149 0.078
Echinococcus granulosus caspase 0.0027 0.0005 0.0003
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0022 0.0022
Onchocerca volvulus Peroxidase homolog 0.0026 0.0005 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0478 0.0763
Plasmodium falciparum DNA topoisomerase 2 0.0026 0.0005 0.0002
Echinococcus granulosus lamin dm0 0.0058 0.0061 0.0195
Loa Loa (eye worm) O-methyltransferase 0.006 0.0065 0.0328
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0026 0.0005 0.0001
Echinococcus granulosus transient receptor potential gamma protein 0.0107 0.0149 0.0498
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0478 0.0763
Treponema pallidum recombinase A 0.0108 0.015 0.2267
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0071 0.0071
Trypanosoma brucei heat shock protein, putative 0.0142 0.0211 1
Loa Loa (eye worm) hypothetical protein 0.0443 0.0746 0.3945
Loa Loa (eye worm) voltage-gated calcium channel 0.0107 0.0149 0.0778
Plasmodium vivax unspecified product 0.0029 0.0009 0.0006
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0107 0.0149 0.0498
Entamoeba histolytica cysteine proteinase, putative 0.0138 0.0203 0.4198
Brugia malayi cathepsin F-like cysteine proteinase 0.0029 0.0009 0.0036
Leishmania major cathepsin L-like protease 0.0138 0.0203 0.0688
Echinococcus granulosus voltage gated hydrogen channel 1 0.0107 0.0149 0.0498
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0107 0.0149 0.0149
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.012 0.0171 0.084
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0107 0.0149 0.0498
Trypanosoma cruzi cruzipain precursor, putative 0.0044 0.0037 0.1411
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.0125 0.0194
Echinococcus multilocularis cathepsin L 0.0073 0.0088 0.0287
Brugia malayi Transient-receptor-potential like protein 0.0107 0.0149 0.078
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0013
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0029 0.0009 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0138 0.0203 0.032
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0029 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0122 0.0176 0.0919
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0004 0.0071
Plasmodium vivax serine-repeat antigen (SERA) 0.0029 0.0009 0.0006
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.081 0.14 0.4796
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0011 0.0008
Leishmania major cysteine peptidase A (CPA) 0.0138 0.0203 0.0688
Trypanosoma brucei methionine aminopeptidase 2, putative 0.0047 0.0042 0.1877
Leishmania major cathepsin L-like protease 0.0138 0.0203 0.0688
Loa Loa (eye worm) methionine aminopeptidase type I 0.005 0.0048 0.0238
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0107 0.0149 0.0498
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0005 0.0001
Echinococcus multilocularis caspase 2 0.0027 0.0005 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0107 0.0149 0.0498
Plasmodium vivax endoplasmin, putative 0.0142 0.0211 0.0208
Trypanosoma brucei heat shock protein 84, putative 0.007 0.0082 0.3823
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.007 0.0083 0.3325
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.012
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0016
Treponema pallidum methionine aminopeptidase (map) 0.0034 0.0018 0.0214
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0042 0.0127
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Trypanosoma brucei heat shock protein, putative 0.0142 0.0211 1
Loa Loa (eye worm) ion channel NompC 0.0107 0.0149 0.0778
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0203 0.963
Giardia lamblia Cathepsin B precursor 0.0069 0.0081 0.0077
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0009 0.0036
Loa Loa (eye worm) hypothetical protein 0.0058 0.0061 0.0309
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.0026 0.0123
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0076 0.0244
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0107 0.0149 0.0498
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0107 0.0149 0.0149
Echinococcus granulosus two pore calcium channel protein 2 0.0107 0.0149 0.0498
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0107 0.0149 0.0498
Trypanosoma cruzi DNA repair protein, putative 0.0033 0.0017 0.0595
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0047 0.0235
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Trypanosoma cruzi DNA topoisomerase II, putative 0.0026 0.0005 0.0076
Trypanosoma cruzi metacaspase, putative 0.0027 0.0005 0.0099
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0646
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Echinococcus granulosus methionyl aminopeptidase 1 M24 family 0.005 0.0048 0.0149
Loa Loa (eye worm) RNA binding protein 0.0063 0.0071 0.036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0138 0.0203 0.032
Loa Loa (eye worm) heat shock protein 75 0.007 0.0082 0.0422
Plasmodium falciparum serine repeat antigen 2 0.0029 0.0009 0.0006
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0004 0.0001
Trypanosoma brucei heat shock protein, putative 0.0142 0.0211 1
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0088 0.3543
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0107 0.0149 0.0498
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Brugia malayi cathepsin L-like cysteine proteinase 0.0029 0.0009 0.0036
Mycobacterium tuberculosis Methionine aminopeptidase MapB (map) (peptidase M) 0.0034 0.0018 0.0023
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0076 0.349
Entamoeba histolytica cysteine proteinase, putative 0.0073 0.0088 0.1762
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.007 0.0082 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0071 0.036
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0088 0.0454
Schistosoma mansoni thyroid hormone receptor 0.0038 0.0026 0.0026
Brugia malayi olfactory channel protein osm-9 0.0108 0.015 0.0782
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0026 0.0005 0.0076
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0107 0.0149 0.078
Plasmodium falciparum metacaspase-like protein 0.0027 0.0005 0.0002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0029 0.0009 0.0009
Onchocerca volvulus 0.0094 0.0125 0.1616
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.007 0.0083 0.0423
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0005 0.0001
Schistosoma mansoni transient receptor potential channel 4 0.0107 0.0149 0.0149
Trypanosoma cruzi metacaspase, putative 0.0027 0.0005 0.0099
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0138 0.0203 0.032
Loa Loa (eye worm) hypothetical protein 0.0064 0.0072 0.0364
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0107 0.0149 0.611
Entamoeba histolytica hypothetical protein 0.0036 0.0022 0.0373
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0022 0.0061
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0005 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.0026 0.0123
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.012
Onchocerca volvulus Huntingtin homolog 0.0122 0.0176 0.231
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0005 0.0013
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0005 0.0013
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0069 0.0081 0.0269
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Echinococcus granulosus cathepsin L cysteine proteinase 0.0138 0.0203 0.0683
Schistosoma mansoni microtubule-associated protein tau 0.1481 0.2593 0.2593
Schistosoma mansoni steroid hormone receptor ad4bp 0.0038 0.0026 0.0026
Plasmodium vivax vivapain-3 0.0073 0.0088 0.0085
Leishmania major methionine aminopeptidase 2, putative 0.0047 0.0042 0.0134
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0005 0.0001
Plasmodium vivax serine-repeat antigen (SERA) 0.0029 0.0009 0.0006
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0022 0.0061
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0011 0.0011
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0107 0.0149 0.1952
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0005 0.0001
Echinococcus multilocularis transient receptor potential cation channel 0.0107 0.0149 0.0498
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0107 0.0149 0.0234
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.018
Echinococcus granulosus cathepsin l cysteine peptidase 0.0138 0.0203 0.0683
Plasmodium vivax vivapain-2 0.0138 0.0203 0.02
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0026 0.0072
Giardia lamblia Cathepsin B precursor 0.0029 0.0009 0.0005
Plasmodium vivax heat shock protein 90, putative 0.007 0.0082 0.008
Echinococcus granulosus voltage dependent calcium channel 0.0107 0.0149 0.0498
Echinococcus multilocularis sodium channel protein 0.1662 0.2915 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Schistosoma mansoni hypothetical protein 0.0041 0.0031 0.0031
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0066 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0005 0.0001
Echinococcus granulosus potassium voltage gated channel protein 0.0107 0.0149 0.0498
Echinococcus granulosus lamin 0.0058 0.0061 0.0195
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0027 0.0005 0.0003
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0071 0.0228
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Giardia lamblia Cysteine protease 0.0029 0.0009 0.0005
Mycobacterium ulcerans methyltransferase 0.006 0.0065 0.0611
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0107 0.0149 0.0149
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0069 0.0081 0.0081
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0203 0.8355
Brugia malayi hypothetical protein 0.0107 0.0149 0.078
Plasmodium falciparum cysteine proteinase falcipain 1 0.0073 0.0088 0.0085
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.0328 0.1728
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0005 0.0002
Brugia malayi jmjC domain containing protein 0.0059 0.0063 0.032
Plasmodium falciparum metacaspase 1 0.0027 0.0005 0.0002
Schistosoma mansoni lamin 0.0058 0.0061 0.0061
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0038 0.0026 0.028
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0069 0.0081 0.0124
Entamoeba histolytica cysteine protease, putative 0.0138 0.0203 0.4198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0084 0.0107 0.0354
Loa Loa (eye worm) hypothetical protein 0.0107 0.0149 0.0778
Onchocerca volvulus 0.0058 0.0061 0.076
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0029 0.0009 0.0008
Echinococcus granulosus heat shock protein 90 0.0142 0.0211 0.0709
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0063 0.02
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0063 0.02
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0478 0.0763
Brugia malayi intermediate filament protein 0.0058 0.0061 0.0312
Plasmodium falciparum flap endonuclease 1 0.0026 0.0004 0.0001
Brugia malayi heat shock protein 90 0.0142 0.0211 0.1107
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0047 0.0233
Loa Loa (eye worm) hypothetical protein 0.0028 0.0008 0.0026
Trichomonas vaginalis heat shock protein, putative 0.0142 0.0211 0.0333
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0076 0.0249
Entamoeba histolytica hypothetical protein 0.0036 0.0022 0.0373
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0026 0.0005 0.0088
Brugia malayi hypothetical protein 0.0443 0.0746 0.3947
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0009 0.0017
Schistosoma mansoni transient receptor potential channel 0.0108 0.015 0.015
Schistosoma mansoni jun-related protein 0.0068 0.0079 0.0079
Echinococcus multilocularis short transient receptor potential channel 6 0.0108 0.015 0.0499
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0047 0.0042 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0029 0.0009 0.0008
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Echinococcus multilocularis potassium voltage gated channel protein 0.0107 0.0149 0.0498
Schistosoma mansoni cathepsin F (C01 family) 0.0094 0.0125 0.0125
Entamoeba histolytica cysteine protease, putative 0.0073 0.0088 0.1762
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Trypanosoma brucei heat shock protein 90, putative 0.0142 0.0211 1
Brugia malayi hypothetical protein 0.0036 0.0022 0.0104
Loa Loa (eye worm) hypothetical protein 0.0057 0.0059 0.0299
Leishmania major heat shock protein 83-1 0.0142 0.0211 0.0714
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0138 0.0203 0.032
Toxoplasma gondii methionine aminopeptidase, type i, putative 0.0034 0.0018 0.0016
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0107 0.0149 0.0498
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0042 0.0127
Echinococcus multilocularis caspase 0.0027 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0646
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0203 0.963
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0129 0.0207
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0149 0.0149
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0026 0.0123
Loa Loa (eye worm) TOPoisomerase family member 0.0026 0.0005 0.001

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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