Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | ap endonuclease, putative | 0.0065 | 0.0641 | 0.6704 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Brugia malayi | nuclear receptor RXR | 0.0054 | 0.0472 | 0.0472 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.062 | 0.062 |
Echinococcus granulosus | FTZ F1 alpha | 0.0102 | 0.124 | 0.2276 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0102 | 0.124 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0048 | 0.038 | 0.0697 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0048 | 0.038 | 0.038 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0184 | 0.5 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0142 | 0.1876 | 0.3442 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0065 | 0.0641 | 0.1477 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Brugia malayi | conserved hypotetical protein | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0776 | 0.0776 |
Brugia malayi | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.062 | 0.1137 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.062 | 0.1137 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0224 | 0.0224 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.0296 | 0.0543 |
Loa Loa (eye worm) | hypothetical protein | 0.0651 | 1 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0065 | 0.0641 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Entamoeba histolytica | hypothetical protein | 0.0193 | 0.2687 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.0296 | 0.244 |
Schistosoma mansoni | ap endonuclease | 0.0065 | 0.0641 | 0.1175 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0065 | 0.0641 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.062 | 0.1137 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0102 | 0.124 | 0.124 |
Entamoeba histolytica | hypothetical protein | 0.0193 | 0.2687 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0339 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0102 | 0.124 | 0.124 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0102 | 0.124 | 0.2276 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0065 | 0.0641 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0595 | 0.1092 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0146 | 0.1939 | 0.3558 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0048 | 0.038 | 0.0697 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0054 | 0.0472 | 0.0472 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0142 | 0.1876 | 0.3442 |
Schistosoma mansoni | thyroid hormone receptor | 0.0244 | 0.3505 | 0.6431 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0193 | 0.2687 | 0.493 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0048 | 0.038 | 0.0697 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Echinococcus granulosus | geminin | 0.0366 | 0.5449 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.062 | 0.062 |
Brugia malayi | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | nuclear receptor | 0.0048 | 0.038 | 0.0697 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0048 | 0.038 | 0.0697 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Brugia malayi | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0048 | 0.038 | 0.0697 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0102 | 0.124 | 0.2276 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0054 | 0.0472 | 0.0866 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.062 | 0.062 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0485 | 0.7349 | 0.7349 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0065 | 0.0641 | 0.0641 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0065 | 0.0641 | 0.1175 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0339 | 0.0623 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0102 | 0.124 | 0.2276 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0065 | 0.0641 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0102 | 0.124 | 0.124 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0102 | 0.124 | 0.2276 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0102 | 0.124 | 0.124 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0142 | 0.1874 | 0.3438 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.062 | 0.1137 |
Schistosoma mansoni | ap endonuclease | 0.0065 | 0.0641 | 0.1175 |
Toxoplasma gondii | exonuclease III APE | 0.0065 | 0.0641 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0142 | 0.1876 | 0.3442 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0184 | 0.0184 |
Brugia malayi | nuclear receptor NHR-88 | 0.0102 | 0.124 | 0.124 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0102 | 0.124 | 0.124 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0184 | 0.0338 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0102 | 0.124 | 0.124 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0048 | 0.038 | 0.0697 |
Schistosoma mansoni | hypothetical protein | 0.0366 | 0.5449 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0339 | 0.0623 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0102 | 0.124 | 0.124 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.062 | 0.1137 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0224 | 0.0224 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0102 | 0.124 | 0.124 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0048 | 0.038 | 0.038 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0595 | 0.1092 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0084 | 0.0953 | 0.1749 |
Brugia malayi | nuclear hormone receptor | 0.0102 | 0.124 | 0.124 |
Onchocerca volvulus | 0.0048 | 0.038 | 0.185 | |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0184 | 0.5 |
Brugia malayi | nuclear hormone receptor | 0.0048 | 0.038 | 0.038 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.9005 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0102 | 0.124 | 0.2276 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0054 | 0.0472 | 0.0866 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0184 | 0.0184 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0399 | 0.0731 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.133 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.0296 | 0.1636 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0193 | 0.2687 | 0.493 |
Brugia malayi | nuclear receptor RXR | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0092 | 0.1076 | 0.1975 |
Brugia malayi | RNA binding protein | 0.0063 | 0.062 | 0.062 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0054 | 0.0472 | 0.0866 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0102 | 0.124 | 0.124 |
Entamoeba histolytica | hypothetical protein | 0.0193 | 0.2687 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0366 | 0.5449 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.9005 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0054 | 0.0472 | 0.0866 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0224 | 0.0411 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0102 | 0.124 | 0.124 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0048 | 0.038 | 0.0697 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0048 | 0.038 | 0.038 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0102 | 0.124 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.0337 | 0.499 | 0.9157 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0054 | 0.0472 | 0.0472 |
Loa Loa (eye worm) | acetyltransferase | 0.0146 | 0.1939 | 0.1939 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0102 | 0.124 | 0.124 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0048 | 0.038 | 0.185 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0184 | 0.0338 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0065 | 0.0641 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0102 | 0.124 | 0.124 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0048 | 0.038 | 0.0697 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0339 | 0.0623 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0048 | 0.038 | 0.038 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0065 | 0.0641 | 0.6704 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.9005 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.062 | 0.1137 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.0296 | 0.244 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.062 | 0.062 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0048 | 0.038 | 0.0697 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0102 | 0.124 | 0.2276 |
Onchocerca volvulus | 0.0102 | 0.124 | 1 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0102 | 0.124 | 0.124 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0092 | 0.1076 | 0.1975 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0339 | 0.0339 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0102 | 0.124 | 0.2276 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0048 | 0.038 | 0.185 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0065 | 0.0641 | 0.1642 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0065 | 0.0641 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0065 | 0.0641 | 0.0641 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0339 | 0.0623 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0184 | 0.0184 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0054 | 0.0472 | 0.0472 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0184 | 0.0184 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0184 | 0.0338 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0048 | 0.038 | 0.038 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0048 | 0.038 | 0.0697 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0146 | 0.1939 | 0.1939 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0048 | 0.038 | 0.038 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0079 | 0.0865 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0339 | 0.0623 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.1092 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0102 | 0.124 | 0.124 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0048 | 0.038 | 0.038 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | nuclear hormone receptor | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.2687 | 0.493 |
Brugia malayi | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0084 | 0.0953 | 0.0953 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.0296 | 0.244 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0102 | 0.124 | 0.124 |
Brugia malayi | hypothetical protein | 0.0193 | 0.2687 | 0.2687 |
Echinococcus multilocularis | geminin | 0.0366 | 0.5449 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0244 | 0.3505 | 0.6431 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Schistosoma mansoni | nuclear hormone receptor | 0.0048 | 0.038 | 0.0697 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0048 | 0.038 | 0.0697 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Schistosoma mansoni | coup transcription factor | 0.0102 | 0.124 | 0.2276 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.9005 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0065 | 0.0641 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0102 | 0.124 | 0.2276 |
Echinococcus granulosus | tumor protein p63 | 0.0337 | 0.499 | 0.9157 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0048 | 0.038 | 0.0697 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.1092 |
Brugia malayi | tailless protein | 0.0048 | 0.038 | 0.038 |
Brugia malayi | ecdysteroid receptor | 0.0102 | 0.124 | 0.124 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0102 | 0.124 | 0.124 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0102 | 0.124 | 0.124 |
Brugia malayi | nuclear receptor NHR-67 | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0102 | 0.124 | 0.2276 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.0296 | 0.1636 |
Brugia malayi | nuclear receptor NHR-88 | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | thyroid hormone receptor | 0.0244 | 0.3505 | 0.6431 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0102 | 0.124 | 0.124 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0065 | 0.0641 | 0.1175 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0102 | 0.124 | 0.124 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0102 | 0.124 | 0.2276 |
Onchocerca volvulus | 0.0049 | 0.0399 | 0.2028 | |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0065 | 0.0641 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0048 | 0.038 | 0.0697 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0084 | 0.0953 | 0.1749 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.062 | 0.062 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0084 | 0.0953 | 0.0953 |
Brugia malayi | ecdysone receptor | 0.0048 | 0.038 | 0.038 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0065 | 0.0641 | 0.5 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0184 | 0.0184 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0102 | 0.124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0102 | 0.124 | 0.2276 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0048 | 0.038 | 0.0697 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0595 | 0.9005 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0339 | 0.0623 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0193 | 0.2687 | 0.493 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0102 | 0.124 | 0.2276 |
Brugia malayi | follicle stimulating hormone receptor | 0.0485 | 0.7349 | 0.7349 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0048 | 0.038 | 0.0697 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0102 | 0.124 | 0.2276 |
Onchocerca volvulus | 0.0048 | 0.038 | 0.185 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0102 | 0.124 | 0.124 |
Entamoeba histolytica | hypothetical protein | 0.0193 | 0.2687 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0065 | 0.0641 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0079 | 0.0865 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0229 | 0.3273 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0048 | 0.038 | 0.0697 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.062 | 0.1137 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0102 | 0.124 | 0.2276 |
Brugia malayi | steroid hormone receptor | 0.0102 | 0.124 | 0.124 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0339 | 0.0623 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0146 | 0.1939 | 0.3558 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.0508 | 0.0508 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0184 | 0.0338 |
Schistosoma mansoni | zinc finger protein | 0.0048 | 0.038 | 0.0697 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0048 | 0.038 | 0.0697 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | > 100 uM | Inhibition of Mycobacterium tuberculosis recombinant MbtA expressed in Escherichia coli by ATP/PPi exchange assay | ChEMBL. | 17967002 |
MIC99 (functional) | > 200 uM | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in iron deficient GAST medium | ChEMBL. | 17967002 |
MIC99 (functional) | > 200 uM | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in iron rich GAST medium | ChEMBL. | 17967002 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.