Detailed information for compound 1140184

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 232.239 | Formula: C11H12N4O2
  • H donors: 1 H acceptors: 2 LogP: -0.96 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCc1nc2c3n1CCN=C3C=C(C2=O)N
  • InChi: 1S/C11H12N4O2/c1-17-5-8-14-9-10-7(4-6(12)11(9)16)13-2-3-15(8)10/h4H,2-3,5,12H2,1H3
  • InChiKey: FHHGXPUBRFZSLV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.0132 0.0162
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0737 0.445 1
Entamoeba histolytica hypothetical protein 0.0058 0.0227 0.029
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0029 0.0043 0.0061
Toxoplasma gondii bromodomain-containing protein 0.0028 0.0039 0.0063
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.009 0.0106
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.0044
Schistosoma mansoni DNA polymerase IV / kappa 0.0089 0.0422 0.0547
Brugia malayi Bromodomain containing protein 0.0028 0.0039 0.0044
Trichomonas vaginalis bromodomain containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Onchocerca volvulus 0.0029 0.0043 0.0004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0157 0.0157
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Brugia malayi hypothetical protein 0.1423 0.8718 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0086 0.0402 0.0583
Loa Loa (eye worm) hypothetical protein 0.0128 0.0661 0.0757
Echinococcus granulosus phosphoglycerate kinase 1 0.0737 0.445 0.6469
Schistosoma mansoni chromobox protein 0.0221 0.1239 0.1612
Echinococcus granulosus 6 phosphofructokinase 0.0345 0.2009 0.292
Trypanosoma cruzi small ubiquitin protein, putative 0.0122 0.0626 0.0626
Trichomonas vaginalis bromodomain containing protein, putative 0.0028 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Echinococcus granulosus ubiquitin 0.0058 0.0227 0.0329
Echinococcus granulosus methyl CpG binding domain protein 2 0.0092 0.0438 0.0634
Echinococcus multilocularis zinc finger protein 0.0122 0.0628 0.0911
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0038 0.0099 0.0142
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Schistosoma mansoni jumonji/arid domain-containing protein 0.029 0.1673 0.2176
Entamoeba histolytica phosphofructokinase, putative 0.0345 0.2009 0.2676
Schistosoma mansoni methyl-cpg binding protein mbd 0.0092 0.0438 0.0568
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0128 0.0661 0.1217
Trichomonas vaginalis ubiquitin, putative 0.0058 0.0227 0.029
Brugia malayi hypothetical protein 0.0058 0.0227 0.026
Treponema pallidum ATP-dependent DNA helicase 0.0101 0.0492 0.0294
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.009 0.0106
Trichomonas vaginalis antibiotic synthetase, putative 0.0038 0.0099 0.0117
Entamoeba histolytica acyl-CoA synthetase, putative 0.0128 0.0661 0.087
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0224 0.126 0.126
Schistosoma mansoni cpg binding protein 0.0042 0.0126 0.0163
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0288 0.1658 0.2408
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0081 0.0369 0.0422
Schistosoma mansoni polymyositis/scleroderma autoantigen-related 0.0028 0.0038 0.0048
Plasmodium vivax SET domain containing protein 0.0033 0.0073 0.0139
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0125 0.0643 0.1423
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.009 0.0106
Plasmodium vivax flap endonuclease 1, putative 0.0084 0.0388 0.0848
Trichomonas vaginalis bromodomain containing protein, putative 0.0028 0.0039 0.0038
Brugia malayi acetyltransferase, GNAT family protein 0.0634 0.3811 0.4371
Trypanosoma brucei hypothetical protein, conserved 0.0081 0.0369 0.0366
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0427 0.0766
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0036 0.009 0.0178
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Schistosoma mansoni cpg binding protein 0.003 0.0052 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0082 0.0095
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0048 0.0165 0.0238
Loa Loa (eye worm) hypothetical protein 0.0125 0.0641 0.0734
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0093 0.0445 0.058
Entamoeba histolytica hypothetical protein 0.0036 0.009 0.0106
Plasmodium vivax DNA repair protein REV1, putative 0.0089 0.0422 0.0924
Loa Loa (eye worm) RecQ helicase 0.0326 0.1896 0.2174
Echinococcus multilocularis SAM and MBT domain containing protein 0.0204 0.1134 0.1647
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0061 0.0067
Trichomonas vaginalis penicillin-binding protein, putative 0.0081 0.0369 0.0479
Brugia malayi bromodomain containing protein 0.0028 0.0039 0.0044
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0133 0.069 0.0897
Trichomonas vaginalis chromobox protein, putative 0.0221 0.1239 0.1645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0023 0.0015
Schistosoma mansoni dep domain containing protein 0.0029 0.0043 0.0054
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0103 0.0509 0.0666
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0026 0.002
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0038 0.0103 0.0103
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Leishmania major DNA polymerase kappa, putative 0.0324 0.1879 0.1879
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0427 0.0766
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0084 0.0388 0.0388
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.1103 0.1463
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0041 0.0119 0.0116
Trypanosoma brucei Bromodomain, putative 0.0028 0.0039 0.0036
Brugia malayi PHD-finger family protein 0.0053 0.0194 0.0221
Brugia malayi ATPase, AAA family protein 0.0028 0.0039 0.0044
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0288 0.1658 0.2408
Brugia malayi Bromodomain containing protein 0.0028 0.0039 0.0044
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0113 0.0136
Trypanosoma cruzi DNA polymerase eta, putative 0.0398 0.2344 0.2344
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0345 0.2009 0.2007
Schistosoma mansoni hypothetical protein 0.0099 0.0483 0.0627
Mycobacterium ulcerans acyl-CoA synthetase 0.0038 0.0099 0.0131
Leishmania major hypothetical protein, conserved 0.0081 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.004 0.0114 0.013
Echinococcus granulosus chromobox protein 1 0.0221 0.1239 0.18
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0128 0.0661 0.1412
Trypanosoma brucei Bromodomain factor 1 0.0028 0.0039 0.0036
Schistosoma mansoni regulator of G protein signaling 0.005 0.0175 0.0226
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0074 0.0327 0.0324
Loa Loa (eye worm) flap endonuclease-1 0.0084 0.0388 0.0443
Brugia malayi Bromodomain containing protein 0.0028 0.0039 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.0093 0.0445 0.058
Trichomonas vaginalis ap endonuclease, putative 0.0081 0.0372 0.0483
Plasmodium falciparum acyl-CoA synthetase 0.0096 0.046 0.101
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0123 0.0632 0.0918
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0101 0.0492 0.0492
Trypanosoma cruzi phosphoglycerate kinase, putative 0.027 0.1548 0.1548
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.009 0.0116
Schistosoma mansoni inositol monophosphatase 0.0043 0.0131 0.0169
Loa Loa (eye worm) transcription factor SMAD2 0.0261 0.1488 0.1706
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0028 0.0039 0.0056
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0011 0.0011
Echinococcus granulosus dna polymerase kappa 0.0431 0.255 0.3706
Loa Loa (eye worm) hypothetical protein 0.0398 0.2344 0.2687
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0114 0.0138
Trichomonas vaginalis bromodomain-containing protein, putative 0.0195 0.1082 0.1434
Giardia lamblia Kinase, putative 0.0028 0.0039 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Brugia malayi serine/threonine-protein kinase plk-2 0.0199 0.1103 0.1264
Entamoeba histolytica hypothetical protein 0.0026 0.0026 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0345 0.2009 0.2676
Schistosoma mansoni phd finger protein 0.0028 0.0039 0.005
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0038 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.009 0.0106
Trichomonas vaginalis hypothetical protein 0.0036 0.009 0.0106
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0102
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.0044
Trypanosoma brucei phosphoglycerate kinase 0.0737 0.445 0.4449
Onchocerca volvulus 0.0081 0.0369 0.0379
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0197 0.1094 0.1254
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Brugia malayi M-phase phosphoprotein, mpp8 0.0036 0.009 0.0102
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0038 0.0103 0.0122
Schistosoma mansoni 6-phosphofructokinase 0.0345 0.2009 0.2614
Schistosoma mansoni tar DNA-binding protein 0.0268 0.1531 0.1992
Echinococcus multilocularis lysine specific demethylase 5A 0.0278 0.1598 0.2321
Trichomonas vaginalis DNA helicase recq1, putative 0.0326 0.1896 0.2525
Loa Loa (eye worm) jmjC domain-containing protein 0.029 0.1673 0.1917
Brugia malayi hypothetical protein 0.0034 0.0075 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.005 0.0175 0.0199
Onchocerca volvulus 0.003 0.0052 0.0014
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0043 0.013 0.0268
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Entamoeba histolytica bromodomain-containing protein 0.0028 0.0039 0.0038
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0737 0.445 1
Trypanosoma brucei DNA polymerase IV, putative 0.0431 0.255 0.2547
Schistosoma mansoni cellular tumor antigen P53 0.0165 0.0892 0.116
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0133 0.069 0.1002
Schistosoma mansoni bromodomain containing protein 0.0028 0.0039 0.005
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0199 0.1103 0.1603
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0356 0.208 0.208
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.0327 0.0374
Schistosoma mansoni hypothetical protein 0.1256 0.7682 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0084 0.0388 0.0848
Echinococcus multilocularis 6 phosphofructokinase 0.0345 0.2009 0.292
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0197 0.1094 0.1254
Loa Loa (eye worm) hypothetical protein 0.0097 0.0472 0.054
Giardia lamblia Hypothetical protein 0.0028 0.0039 0.0063
Entamoeba histolytica deoxycytidyl transferase, putative 0.0288 0.1658 0.2205
Schistosoma mansoni DNA helicase recq1 0.0197 0.1094 0.1423
Plasmodium vivax small ubiquitin-related modifier, putative 0.0122 0.0626 0.1385
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.003 0.0053 0.0056
Echinococcus multilocularis survival motor neuron protein 1 0.0486 0.2893 0.4204
Loa Loa (eye worm) hypothetical protein 0.0233 0.1314 0.1506
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0737 0.445 0.5947
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0038 0.0103 0.0122
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.009 0.0106
Plasmodium vivax hypothetical protein, conserved 0.0036 0.009 0.0178
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trypanosoma cruzi Bromodomain, putative 0.0028 0.0039 0.0039
Onchocerca volvulus 0.0038 0.0099 0.0068
Echinococcus multilocularis polycomb protein SCMH1 0.0204 0.1134 0.1647
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0737 0.445 0.5947
Mycobacterium ulcerans acetyl-CoA synthetase 0.0038 0.0099 0.0131
Trypanosoma cruzi Bromodomain, putative 0.0028 0.0039 0.0039
Trypanosoma cruzi Bromodomain, putative 0.0028 0.0039 0.0039
Toxoplasma gondii bromodomain-containing protein 0.0028 0.0039 0.0063
Giardia lamblia Hypothetical protein 0.0028 0.0039 0.0063
Leishmania major DNA polymerase kappa, putative 0.0089 0.0422 0.0422
Brugia malayi hypothetical protein 0.0029 0.0043 0.0048
Echinococcus multilocularis Chromobox protein 3 0.0036 0.009 0.0129
Plasmodium falciparum importin beta, putative 0.0032 0.0064 0.0118
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0345 0.2009 0.4468
Echinococcus multilocularis dnaJ subfamily B 0.0427 0.2521 0.3663
Echinococcus granulosus protein kinase C binding protein 1 0.0028 0.0039 0.0056
Brugia malayi CXXC zinc finger family protein 0.003 0.0052 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.0626 0.0824
Brugia malayi polybromodomain protein 0.0028 0.0039 0.0044
Plasmodium vivax exosome complex exonuclease RRP6, putative 0.0028 0.0038 0.006
Brugia malayi Associated with TFs and helicases family protein 0.0036 0.009 0.0102
Schistosoma mansoni chromobox protein 0.0036 0.009 0.0116
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0064 0.0118
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0124 0.0636 0.0687
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0279 0.1602 0.1602
Schistosoma mansoni tar DNA-binding protein 0.0268 0.1531 0.1992
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0093 0.0445 0.058
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0028 0.0039 0.0036
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0064 0.006
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0038 0.0099 0.0131
Schistosoma mansoni blooms syndrome DNA helicase 0.0226 0.127 0.1652
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0098 0.0098
Brugia malayi AF-10 protein 0.0041 0.0119 0.0135
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0197 0.1094 0.1254
Loa Loa (eye worm) hypothetical protein 0.0097 0.0472 0.054
Leishmania major 4-coumarate:coa ligase-like protein 0.0128 0.0661 0.0661
Echinococcus granulosus importin subunit beta 1 0.0032 0.0064 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0634 0.3811 0.554
Trypanosoma brucei DNA polymerase kappa, putative 0.0234 0.1323 0.132
Mycobacterium ulcerans acyl-CoA synthetase 0.0038 0.0099 0.0131
Plasmodium vivax heterochromatin protein 1, putative 0.0036 0.009 0.0178
Toxoplasma gondii ABC1 family protein 0.0081 0.0369 0.0805
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0038 0.0099 0.0117
Loa Loa (eye worm) hypothetical protein 0.0096 0.046 0.0526
Entamoeba histolytica bromodomain-containing protein 0.0028 0.0039 0.0038
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0081 0.0372 0.0658
Brugia malayi beta-lactamase 0.0081 0.0369 0.0422
Leishmania major DNA polymerase eta, putative 0.0398 0.2344 0.2344
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0039 0.0039
Schistosoma mansoni transcription initiation factor tfiid 0.0028 0.0039 0.005
Brugia malayi phosphofructokinase 0.0345 0.2009 0.2304
Toxoplasma gondii small ubiquitin family modifier, putative 0.0122 0.0626 0.1385
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.0028 0.0039 0.0039
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0011 0.0014
Loa Loa (eye worm) bromodomain containing protein 0.0028 0.0039 0.0044
Leishmania major hypothetical protein, conserved 0.0052 0.019 0.019
Schistosoma mansoni eyes absent homolog 0.0097 0.0472 0.0612
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0081 0.0372 0.0812
Echinococcus granulosus cpg binding protein 0.0042 0.0126 0.0182
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0199 0.1103 0.1264
Brugia malayi Bromodomain containing protein 0.0153 0.0815 0.0934
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0232 0.131 0.1903
Entamoeba histolytica acetyltransferase, GNAT family 0.0167 0.0908 0.1201
Trichomonas vaginalis hypothetical protein 0.0028 0.0039 0.0038
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0038 0.0099 0.0112
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0038 0.0099 0.0131
Trichomonas vaginalis bromodomain containing protein, putative 0.0028 0.0039 0.0038
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0038 0.0099 0.0131
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0081 0.0369 0.0479
Leishmania major acetyl-CoA synthetase, putative 0.0038 0.0099 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0023 0.0015
Trypanosoma brucei AAA ATPase, putative 0.0028 0.0039 0.0036
Leishmania major ATP-dependent phosphofructokinase 0.0345 0.2009 0.2009
Trichomonas vaginalis rotamase, putative 0.0106 0.0524 0.0687
Plasmodium vivax bromodomain protein, putative 0.0028 0.0039 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0082 0.0095
Brugia malayi 3'-5' exonuclease family protein 0.0028 0.0038 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0097 0.0115
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0229 0.129 0.1287
Giardia lamblia Kinase, PLK 0.0199 0.1103 0.246
Plasmodium vivax JmjC domain containing protein 0.0074 0.0327 0.0712
Brugia malayi Valyl-tRNA synthetase 0.0036 0.009 0.0102
Loa Loa (eye worm) hypothetical protein 0.0232 0.131 0.1501
Loa Loa (eye worm) hypothetical protein 0.0081 0.0369 0.0422
Trypanosoma brucei small ubiquitin-related modifier 0.0122 0.0626 0.0623
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Loa Loa (eye worm) MBCTL1 0.0232 0.131 0.1501
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0038 0.0099 0.0131
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0038 0.0099 0.0131
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0011 0.0015
Schistosoma mansoni hypothetical protein 0.0028 0.0039 0.005
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0131 0.0161
Echinococcus granulosus polycomb protein SCMH1 0.0204 0.1134 0.1647
Echinococcus multilocularis bromodomain containing protein 8 0.0028 0.0039 0.0056
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0011 0.0008
Brugia malayi PHD-finger family protein 0.0151 0.0807 0.0924
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0039 0.0063
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0038 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0038 0.0099 0.0112
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0038 0.0103 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0097 0.0115
Brugia malayi Phosphoglycerate kinase 0.027 0.1548 0.1775
Plasmodium falciparum phosphoglycerate kinase 0.0737 0.445 1
Loa Loa (eye worm) PHD-finger family protein 0.0111 0.0558 0.0638
Loa Loa (eye worm) hypothetical protein 0.013 0.0676 0.0774
Schistosoma mansoni zinc finger protein 0.0082 0.0379 0.0491
Loa Loa (eye worm) 6-phosphofructokinase 0.0345 0.2009 0.2304
Echinococcus multilocularis JmjC domain containing protein 4 0.0074 0.0327 0.0474
Entamoeba histolytica Flap nuclease, putative 0.0084 0.0388 0.0504
Loa Loa (eye worm) hypothetical protein 0.0248 0.1407 0.1612
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.009 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.019 0.019
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0081 0.0369 0.0422
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.019 0.0403
Echinococcus granulosus flap endonuclease 1 0.0084 0.0388 0.0562
Mycobacterium ulcerans esterase/lipase LipP 0.0081 0.0369 0.0653
Leishmania major DNA polymerase eta, putative 0.02 0.1108 0.1108
Brugia malayi Bromodomain containing protein 0.0028 0.0039 0.0044
Loa Loa (eye worm) CBP-B 0.0028 0.0039 0.0044
Plasmodium vivax SET domain protein, putative 0.0129 0.0666 0.1474
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0634 0.3811 0.4961
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Echinococcus granulosus jumonji domain containing 1A 0.0074 0.0327 0.0474
Loa Loa (eye worm) hypothetical protein 0.1423 0.8718 1
Entamoeba histolytica phosphoglycerate kinase, putative 0.0737 0.445 0.5947
Schistosoma mansoni flap endonuclease-1 0.0076 0.0338 0.0438
Echinococcus granulosus polybromo 1 0.0028 0.0039 0.0056
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0197 0.1094 0.2439
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0081 0.0369 0.0653
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0103 0.014
Mycobacterium ulcerans acyl-CoA synthetase 0.0128 0.0661 0.1217
Loa Loa (eye worm) hypothetical protein 0.0247 0.1402 0.1607
Brugia malayi mbt repeat family protein 0.0204 0.1134 0.13
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0157 0.0227
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0023 0.0015
Trichomonas vaginalis penicillin-binding protein, putative 0.0081 0.0369 0.0479
Trichomonas vaginalis phosphofructokinase, putative 0.0093 0.0445 0.058
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0038 0.0099 0.0112
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.0044
Mycobacterium ulcerans lipase LipD 0.0081 0.0369 0.0653
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0356 0.208 0.2078
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0636 0.0836
Trichomonas vaginalis lymphoid specific helicase, putative 0.0028 0.0039 0.0038
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0106 0.0524 0.06
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.004 0.0038
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0038 0.0099 0.0138
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.019 0.0403
Plasmodium vivax hypothetical protein, conserved 0.0036 0.009 0.0178
Mycobacterium ulcerans DNA polymerase IV 0.0431 0.255 0.487
Entamoeba histolytica acyl-CoA synthetase, putative 0.0128 0.0661 0.087
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Schistosoma mansoni zinc finger protein 0.0122 0.0628 0.0816
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0082 0.0095
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0038 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.1103 0.1463
Trypanosoma brucei DNA polymerase kappa, putative 0.0431 0.255 0.2547
Trichomonas vaginalis phosphofructokinase, putative 0.0093 0.0445 0.058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0427 0.0766
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0131 0.0189
Brugia malayi polk-prov protein 0.0233 0.1314 0.1506
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0123 0.0632 0.0918
Leishmania major importin beta-1 subunit, putative 0.0026 0.0026 0.0026
Echinococcus multilocularis Bromodomain containing protein 0.0028 0.0039 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0431 0.255 0.2547
Brugia malayi RNA recognition motif domain containing protein 0.0268 0.1531 0.1755
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0028 0.0039 0.0038
Leishmania major hypothetical protein, conserved 0.0082 0.0379 0.0379
Entamoeba histolytica hypothetical protein 0.0036 0.009 0.0106
Trypanosoma cruzi bromodomain factor 2 protein 0.0028 0.0039 0.0039
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0066 0.0066
Loa Loa (eye worm) glutaminase 0.0608 0.3647 0.4182
Echinococcus granulosus Chromobox protein 3 0.0036 0.009 0.0129
Echinococcus granulosus Bromodomain containing protein 0.0028 0.0039 0.0056
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0093 0.0445 0.0976
Schistosoma mansoni hypothetical protein 0.0427 0.2521 0.328
Mycobacterium ulcerans acyl-CoA synthetase 0.0038 0.0099 0.0131
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0029 0.0043 0.0054
Echinococcus multilocularis tar DNA binding protein 0.0268 0.1531 0.2224
Trypanosoma cruzi DNA polymerase kappa, putative 0.0431 0.255 0.255
Echinococcus granulosus fetal alzheimer antigen falz 0.0123 0.0632 0.0918
Onchocerca volvulus 0.0036 0.009 0.0058
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0103 0.0509 0.0505
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0038 0.0103 0.0103
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Onchocerca volvulus 0.1423 0.8718 1
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0106 0.0524 0.06
Brugia malayi TAZ zinc finger family protein 0.0028 0.0039 0.0044
Loa Loa (eye worm) hypothetical protein 0.0074 0.0327 0.0374
Trichomonas vaginalis phosphofructokinase, putative 0.0345 0.2009 0.2676
Echinococcus granulosus bloom syndrome protein 0.0326 0.1896 0.2755
Trichomonas vaginalis hypothetical protein 0.0028 0.0039 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0431 0.255 0.2547
Loa Loa (eye worm) hypothetical protein 0.0165 0.0892 0.1022
Echinococcus granulosus segment polarity protein dishevelled 0.0029 0.0043 0.0061
Schistosoma mansoni hypothetical protein 0.034 0.1983 0.258
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.0044
Echinococcus granulosus survival motor neuron protein 1 0.0486 0.2893 0.4204
Brugia malayi hypothetical protein 0.0029 0.0043 0.0048
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0737 0.445 0.8544
Plasmodium vivax acetyl-CoA synthetase, putative 0.0038 0.0099 0.0197
Entamoeba histolytica bromodomain-containing protein 0.0028 0.0039 0.0038
Entamoeba histolytica hypothetical protein 0.0073 0.0322 0.0416
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.009 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0082 0.0095
Toxoplasma gondii exonuclease III APE 0.0081 0.0372 0.0812
Loa Loa (eye worm) hypothetical protein 0.0235 0.1327 0.1521
Loa Loa (eye worm) hypothetical protein 0.0207 0.1153 0.1321
Brugia malayi AMP-binding enzyme family protein 0.0038 0.0099 0.0112
Chlamydia trachomatis phosphoglycerate kinase 0.0737 0.445 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0268 0.1531 0.1755
Echinococcus granulosus dna polymerase eta 0.0398 0.2344 0.3406
Trichomonas vaginalis ap endonuclease, putative 0.0081 0.0372 0.0483
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0028 0.0039 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0128 0.0661 0.0757
Trypanosoma brucei DNA polymerase kappa, putative 0.0233 0.1314 0.1311
Trichomonas vaginalis chromobox protein, putative 0.0036 0.009 0.0106
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0026 0.002
Schistosoma mansoni sex comb on midleg homolog 0.0204 0.1134 0.1475
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0128 0.0661 0.1217
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0221 0.1238 0.1798
Trypanosoma brucei unspecified product 0.0396 0.2329 0.2326
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0132 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Schistosoma mansoni jumonji/arid domain-containing protein 0.029 0.1673 0.2176
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0131 0.0194
Mycobacterium tuberculosis Conserved hypothetical protein 0.0288 0.1658 0.3144
Entamoeba histolytica serine/threonine protein kinase, putative 0.0199 0.1103 0.1463
Loa Loa (eye worm) BRM protein 0.0028 0.0039 0.0044
Schistosoma mansoni chromobox protein 0.0221 0.1239 0.1612
Echinococcus multilocularis Protein lozenge 0.0178 0.0976 0.1417
Schistosoma mansoni hypothetical protein 0.0367 0.2152 0.28
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0038 0.0099 0.0131
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0737 0.445 0.445
Echinococcus multilocularis bromodomain containing 2 0.0028 0.0039 0.0056
Schistosoma mansoni rotamase 0.0106 0.0524 0.0681
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0096 0.046 0.0829
Toxoplasma gondii propionate-CoA ligase 0.0038 0.0099 0.0197
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0038 0.0103 0.0132
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0074 0.0327 0.0712
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0224 0.126 0.1257
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0038 0.0099 0.0197
Schistosoma mansoni protein phosphatase 2C 0.0074 0.0327 0.0425
Brugia malayi Bromodomain containing protein 0.0028 0.0039 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0099 0.0131
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0157 0.0179
Trichomonas vaginalis rotamase, putative 0.0103 0.0509 0.0666
Echinococcus granulosus lysine specific demethylase 6a 0.0074 0.0327 0.0474
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.0132 0.0162
Schistosoma mansoni hypothetical protein 0.0028 0.0039 0.005
Trichomonas vaginalis phosphofructokinase, putative 0.0093 0.0445 0.058
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0771 0.4662 0.4662
Brugia malayi hypothetical protein 0.0052 0.019 0.0217
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.011 0.0132
Echinococcus multilocularis CREB binding protein 0.0028 0.0039 0.0056
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Leishmania major eukaryotic translation initiation factor-like 0.0038 0.0103 0.0103
Plasmodium vivax bromodomain protein, putative 0.0028 0.0039 0.0063
Plasmodium falciparum flap endonuclease 1 0.0084 0.0388 0.0848
Plasmodium falciparum bromodomain protein, putative 0.0028 0.0039 0.0063
Schistosoma mansoni hypothetical protein 0.0125 0.0641 0.0833
Mycobacterium ulcerans beta-lactamase 0.0081 0.0369 0.0653
Loa Loa (eye worm) PHD-finger family protein 0.0125 0.0641 0.0734
Trichomonas vaginalis DNA polymerase eta, putative 0.0431 0.255 0.3401
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0038 0.0099 0.0096
Toxoplasma gondii phosphofructokinase PFKII 0.0093 0.0445 0.0976
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.003 0.0053 0.0056
Echinococcus granulosus jumonji domain containing protein 0.0173 0.0945 0.1372
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1629 1 1
Schistosoma mansoni hypothetical protein 0.0082 0.0379 0.0491
Brugia malayi Protein cec-1. 0.0036 0.009 0.0102
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0032 0.0066 0.0068
Onchocerca volvulus 0.0038 0.0099 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0431 0.255 0.2547
Loa Loa (eye worm) hypothetical protein 0.0204 0.1134 0.13
Trypanosoma brucei DNA polymerase kappa, putative 0.0431 0.255 0.2547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0082 0.0095
Schistosoma mansoni hypothetical protein 0.0023 0.0011 0.0013
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0038 0.0099 0.0112
Schistosoma mansoni blooms syndrome DNA helicase 0.0101 0.0492 0.0639
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0157 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0524 0.0687
Trichomonas vaginalis chromobox protein, putative 0.0036 0.009 0.0106
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0038 0.0099 0.0131
Leishmania major GTP-binding protein, putative 0.0023 0.0011 0.0011
Brugia malayi Inositol-1 0.0043 0.0131 0.0149
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0029 0.0043 0.0048
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.058 0.3474 0.3983
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0128 0.0661 0.1217
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0128 0.0661 0.1217
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0028 0.0039 0.0038
Echinococcus multilocularis global transcription activator snf2l2 0.0028 0.0039 0.0056
Echinococcus multilocularis segment polarity protein dishevelled 0.0029 0.0043 0.0061
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0011 0.0012
Trypanosoma cruzi DNA damage repair protein, putative 0.0089 0.0422 0.0422
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0038 0.0103 0.0103
Brugia malayi DIX domain containing protein 0.0029 0.0043 0.0048
Plasmodium falciparum bromodomain protein 1 0.0028 0.0039 0.0063
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0028 0.0039 0.005
Echinococcus granulosus Helicase RNase D C terminal HRDC domain 0.0028 0.0038 0.0053
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.0327 0.0374
Echinococcus multilocularis microtubule associated protein 2 0.0715 0.4314 0.6271
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0356 0.208 0.208
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Brugia malayi CHD4 protein 0.0048 0.0165 0.0188
Trypanosoma brucei DNA polymerase IV, putative 0.0396 0.2329 0.2326
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.0194 0.0252
Loa Loa (eye worm) hypothetical protein 0.0737 0.445 0.5104
Entamoeba histolytica acyl-coA synthetase, putative 0.0128 0.0661 0.087
Brugia malayi N-terminal motif family protein 0.058 0.3474 0.3983
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Loa Loa (eye worm) oxidoreductase 0.0038 0.0099 0.0112
Echinococcus multilocularis lysine specific demethylase 6a 0.0074 0.0327 0.0474
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0038 0.0099 0.0131
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0862 0.523 0.7603
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0027 0.0031 0.0045
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0133 0.069 0.1002
Echinococcus multilocularis phd:f box containing protein 0.0074 0.0327 0.0474
Schistosoma mansoni survival motor neuron protein 0.0099 0.0483 0.0627
Leishmania major 4-coumarate:coa ligase-like protein 0.0128 0.0661 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0084 0.0388 0.0385
Giardia lamblia PHD finger protein 15 0.0125 0.0641 0.1418
Echinococcus granulosus CREB binding protein 0.0028 0.0039 0.0056
Echinococcus multilocularis Small ubiquitin modifier 2 0.0122 0.0626 0.0909
Schistosoma mansoni hypothetical protein 0.0028 0.0039 0.005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0431 0.255 0.255
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.0044
Echinococcus granulosus tar DNA binding protein 0.0268 0.1531 0.2224
Loa Loa (eye worm) hypothetical protein 0.0096 0.046 0.0526
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0102
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0771 0.4662 0.466
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.019 0.0187
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0038 0.0099 0.0112
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0038 0.0103 0.0149
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0036 0.009 0.0178
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0132 0.0162
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0369 0.0369
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0125 0.0641 0.0833
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0028 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0124 0.0636 0.0728
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0038 0.0099 0.0112
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0038 0.0103 0.0122
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0157 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0411 0.0535
Echinococcus multilocularis ubiquitin 0.0058 0.0227 0.0329
Trichomonas vaginalis D-aminoacylase, putative 0.0081 0.0369 0.0479
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0023 0.0015
Schistosoma mansoni acetyl-CoA synthetase 0.0038 0.0099 0.0127
Loa Loa (eye worm) hypothetical protein 0.0038 0.0099 0.0112
Trypanosoma cruzi hypothetical protein, conserved 0.0089 0.0422 0.0422
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.027 0.1548 0.1548
Loa Loa (eye worm) hypothetical protein 0.0381 0.2239 0.2567
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trichomonas vaginalis phosphofructokinase, putative 0.0345 0.2009 0.2676
Loa Loa (eye worm) hypothetical protein 0.0128 0.0661 0.0757
Entamoeba histolytica recQ family helicase, putative 0.0224 0.126 0.1673
Onchocerca volvulus 0.0099 0.0483 0.0511
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0099 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.009 0.0106
Trichomonas vaginalis glutaminase, putative 0.0608 0.3647 0.487
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.0431 0.255 0.255
Trypanosoma brucei hypothetical protein, conserved 0.0089 0.0422 0.0418
Trypanosoma brucei ribosomal RNA processing protein 6 0.0028 0.0038 0.0035
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0048 0.0165 0.0213
Brugia malayi hypothetical protein 0.013 0.0676 0.0774
Entamoeba histolytica recQ family helicase, putative 0.0097 0.0468 0.0612
Brugia malayi polybromodomain protein 0.0028 0.0039 0.0044
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0157 0.0157
Mycobacterium ulcerans hypothetical protein 0.0128 0.0661 0.1217
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0197 0.1094 0.2439
Trichomonas vaginalis chromobox protein, putative 0.0133 0.0694 0.0915
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0129 0.0666 0.0865
Plasmodium vivax phosphoglycerate kinase, putative 0.0737 0.445 1
Echinococcus multilocularis polybromo 1 0.0028 0.0039 0.0056
Entamoeba histolytica hypothetical protein 0.0036 0.009 0.0106
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0081 0.0372 0.0483
Echinococcus granulosus chromobox protein 2 0.0036 0.009 0.0129
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0288 0.1658 0.2157
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Schistosoma mansoni ran 0.0023 0.0011 0.0013
Leishmania major eukaryotic translation initiation factor-like protein 0.0038 0.0103 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0197 0.1094 0.1589
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis phosphofructokinase, putative 0.0093 0.0445 0.058
Mycobacterium ulcerans hypothetical protein 0.0081 0.0369 0.0653
Trichomonas vaginalis chromobox protein, putative 0.0221 0.1239 0.1645
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0369 0.0369
Onchocerca volvulus Huntingtin homolog 0.013 0.0676 0.0733
Mycobacterium ulcerans hypothetical protein 0.0089 0.0422 0.0755
Brugia malayi BRM protein 0.0028 0.0039 0.0044
Schistosoma mansoni lozenge 0.0178 0.0976 0.1269
Onchocerca volvulus 0.0058 0.0227 0.0217
Toxoplasma gondii hypothetical protein 0.0028 0.0039 0.0063
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.005 0.0175 0.0199
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0131 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0431 0.255 0.2547
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.009 0.0106
Brugia malayi beta-lactamase family protein 0.0081 0.0369 0.0422
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0066 0.0066
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0893 0.5422 0.6218
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0081 0.0372 0.0425
Trypanosoma cruzi ribosomal RNA processing protein 6, putative 0.0028 0.0038 0.0038
Mycobacterium tuberculosis Conserved protein 0.0081 0.0369 0.0653
Loa Loa (eye worm) helicase 0.0036 0.009 0.0102
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0036 0.0087 0.0107
Trichomonas vaginalis DNA helicase recq, putative 0.0224 0.126 0.1673
Brugia malayi jmjC domain containing protein 0.0536 0.3199 0.3669
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis flap endonuclease-1, putative 0.0084 0.0388 0.0504
Echinococcus multilocularis tumor protein p63 0.1127 0.6879 1
Leishmania major exosome subunit rrp6p homologue, putative 0.0028 0.0038 0.0038
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0011 0.0015
Trichomonas vaginalis chromobox protein, putative 0.0133 0.0694 0.0915
Loa Loa (eye worm) hypothetical protein 0.0029 0.0043 0.0048
Echinococcus granulosus JmjC domain containing protein 4 0.0074 0.0327 0.0474
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Toxoplasma gondii PHD-finger domain-containing protein 0.0125 0.0641 0.1418
Leishmania major phosphoglycerate kinase B, cytosolic 0.0737 0.445 0.445
Trypanosoma cruzi polo-like protein kinase, putative 0.0199 0.1103 0.1103
Giardia lamblia GTOR 0.0047 0.0157 0.0328
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0478 0.0625
Echinococcus granulosus regulator of G protein signaling 7 0.005 0.0175 0.0252
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0066 0.0062
Toxoplasma gondii bromodomain-containing protein 0.0028 0.0039 0.0063
Brugia malayi jmjC domain containing protein 0.0074 0.0327 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trypanosoma brucei hypothetical protein, conserved 0.0089 0.0422 0.0418
Loa Loa (eye worm) beta-lactamase 0.0081 0.0369 0.0422
Mycobacterium tuberculosis Probable hydrolase 0.0081 0.0369 0.0653
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0128 0.0661 0.0757
Loa Loa (eye worm) 3'-5' exonuclease 0.0028 0.0038 0.0042
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0737 0.445 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0167 0.0908 0.2019
Brugia malayi Bromodomain containing protein 0.0421 0.2487 0.2852
Schistosoma mansoni hypothetical protein 0.0041 0.0119 0.0153
Echinococcus granulosus chromobox protein 1 0.0221 0.1239 0.18
Toxoplasma gondii 6-phosphofructokinase 0.0093 0.0445 0.0976
Trichomonas vaginalis Heterochromatin protein, putative 0.0036 0.009 0.0106
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.0327 0.0374
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0131 0.027
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0096 0.046 0.0038
Trichomonas vaginalis DNA helicase recq, putative 0.0326 0.1896 0.2525
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0038 0.0099 0.0131
Loa Loa (eye worm) heterochromatin protein 1 0.0221 0.1239 0.1421
Mycobacterium ulcerans hypothetical protein 0.0028 0.0038 0.0013
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0157 0.0179
Onchocerca volvulus 0.0097 0.0469 0.0495
Giardia lamblia DINP protein human, muc B family 0.0324 0.1879 0.4207
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.009 0.0178
Trichomonas vaginalis phosphofructokinase, putative 0.0345 0.2009 0.2676
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0221
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0322 0.0417
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0038 0.0099 0.0138
Mycobacterium tuberculosis Probable lipase LipD 0.0081 0.0369 0.0653
Brugia malayi exodeoxyribonuclease III family protein 0.0081 0.0372 0.0425
Echinococcus multilocularis bloom syndrome protein 0.0326 0.1896 0.2755
Leishmania major DNA damage repair protein, putative 0.0089 0.0422 0.0422
Plasmodium vivax 6-phosphofructokinase, putative 0.0093 0.0445 0.0976
Plasmodium vivax acyl-CoA synthetase, putative 0.0096 0.046 0.101
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.082 0.4968 0.7222
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0093 0.0445 0.0976
Onchocerca volvulus 0.0128 0.0661 0.0716
Brugia malayi Flap endonuclease-1 0.0084 0.0388 0.0443
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0165 0.0891 0.1158
Trypanosoma cruzi bromodomain-containing protein 3 0.0028 0.0039 0.0039
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0132 0.0162
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0221 0.1238 0.161
Schistosoma mansoni glutaminase 0.0608 0.3647 0.4747
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Brugia malayi Ubiquitin-like protein SMT3 0.0122 0.0626 0.0717
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Echinococcus granulosus regulator of G protein signaling 7 0.005 0.0175 0.0252
Entamoeba histolytica dual specificity protein phosphatase, putative 0.1223 0.7476 1
Trypanosoma brucei chrX additional, unordered contigs 0.0089 0.0422 0.0418
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0133 0.0694 0.0754
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.019 0.0403
Echinococcus granulosus microtubule associated protein 2 0.0715 0.4314 0.6271
Brugia malayi Pre-SET motif family protein 0.0129 0.0666 0.0762
Schistosoma mansoni inositol monophosphatase 0.0043 0.0131 0.0169
Schistosoma mansoni ap endonuclease 0.0081 0.0372 0.0482
Echinococcus granulosus Chromo domain 0.0036 0.009 0.0129
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0036 0.009 0.0102
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0157 0.0154
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0132 0.0162
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0103 0.0509 0.0509
Mycobacterium ulcerans acyl-CoA synthetase 0.0038 0.0099 0.0131
Trypanosoma cruzi hypothetical protein, conserved 0.0089 0.0422 0.0422
Onchocerca volvulus Serine\/threonine kinase homolog 0.0199 0.1103 0.1226
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0098 0.0098
Echinococcus multilocularis regulator of G protein signaling 7 0.005 0.0175 0.0252
Mycobacterium ulcerans glutaminase 0.0608 0.3647 0.699
Brugia malayi RNA, U transporter 1 0.0091 0.0429 0.0491
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0197 0.1094 0.1589
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0032 0.0066 0.0122
Entamoeba histolytica recQ family DNA helicase 0.0101 0.0492 0.0643
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0038 0.0103 0.0147
Plasmodium vivax 6-phosphofructokinase, putative 0.0093 0.0445 0.0976
Schistosoma mansoni kinase 0.0101 0.0495 0.0642
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0038 0.0099 0.0099
Mycobacterium ulcerans hypothetical protein 0.0858 0.5204 1
Entamoeba histolytica hypothetical protein 0.0028 0.0039 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0131 0.0189
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0157 0.0157
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0081 0.0372 0.0369
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0345 0.2009 0.3824
Toxoplasma gondii PHD-finger domain-containing protein 0.0125 0.0641 0.1418
Loa Loa (eye worm) hypothetical protein 0.0058 0.0227 0.026
Plasmodium falciparum JmjC domain-containing protein, putative 0.0074 0.0327 0.0712
Loa Loa (eye worm) hypothetical protein 0.0029 0.0043 0.0048
Echinococcus granulosus endonuclease exonuclease phosphatase 0.082 0.4968 0.7222
Trypanosoma cruzi polo-like protein kinase, putative 0.0199 0.1103 0.1103
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0038 0.0099 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0082 0.0095
Loa Loa (eye worm) hypothetical protein 0.0101 0.0492 0.0563
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0081 0.0369 0.0653
Toxoplasma gondii 3'-5' exonuclease domain-containing protein 0.0028 0.0038 0.006
Loa Loa (eye worm) bromodomain containing protein 0.011 0.0553 0.0633
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0011 0.0011
Echinococcus granulosus transcription factor Dp 1 0.0206 0.1148 0.1667
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0132 0.0162
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0028 0.0039 0.0063
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0232 0.131 0.1501
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0102
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0099 0.0131
Echinococcus granulosus zinc finger protein 0.0122 0.0628 0.0911
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0131 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Echinococcus granulosus PHD finger protein rhinoceros 0.0125 0.0641 0.093
Trypanosoma cruzi phosphoglycerate kinase, putative 0.027 0.1548 0.1548
Trichomonas vaginalis D-aminoacylase, putative 0.0081 0.0369 0.0479
Trichomonas vaginalis D-aminoacylase, putative 0.0081 0.0369 0.0479
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0197 0.1094 0.1589
Plasmodium vivax bromodomain protein, putative 0.0028 0.0039 0.0063
Plasmodium vivax hypothetical protein, conserved 0.0125 0.0641 0.1418
Trypanosoma brucei DNA polymerase kappa, putative 0.0233 0.1314 0.1311
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0052 0.0058
Schistosoma mansoni cpg binding protein 0.0042 0.0126 0.0163
Entamoeba histolytica bromodomain-containing protein 0.0028 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0483 0.0553
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0103 0.0509 0.0509
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.058 0.3474 0.3957
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0023 0.0015
Echinococcus granulosus lysine specific demethylase 5A 0.029 0.1673 0.243
Brugia malayi AMP-binding enzyme family protein 0.0128 0.0661 0.0757
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0356 0.208 0.3023
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0737 0.445 1
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0356 0.208 0.2385
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Schistosoma mansoni DNA polymerase eta 0.0398 0.2344 0.305
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0229 0.129 0.129
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0204 0.1134 0.1261
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0203 0.1128 0.2515
Echinococcus multilocularis protein kinase C binding protein 1 0.0028 0.0039 0.0056
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0133 0.069 0.0791
Leishmania major hypothetical protein, conserved 0.0028 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.0044
Leishmania major phosphoglycerate kinase C, glycosomal 0.0737 0.445 0.445
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0036 0.009 0.0129
Echinococcus multilocularis cpg binding protein 0.0042 0.0126 0.0182
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0356 0.208 0.2385
Echinococcus multilocularis 0.0028 0.0039 0.0056
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0322 0.0466
Mycobacterium leprae Probable lipase LipE 0.0081 0.0369 0.075
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0431 0.255 0.3401
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0133 0.069 0.1002
Loa Loa (eye worm) 6-phosphofructokinase 0.0345 0.2009 0.2304
Echinococcus multilocularis jumonji domain containing protein 0.0173 0.0945 0.1372
Trypanosoma brucei DNA damage repair protein, putative 0.0089 0.0422 0.0418
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0038 0.0099 0.0096
Schistosoma mansoni bromodomain containing protein 0.004 0.0114 0.0147
Brugia malayi translation initiation factor 4E 0.0038 0.0103 0.0116
Entamoeba histolytica phosphofructokinase, putative 0.0345 0.2009 0.2676
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.0028 0.0039 0.0039
Echinococcus multilocularis dna polymerase kappa 0.0431 0.255 0.3706
Trypanosoma cruzi Bromodomain factor 1 0.0028 0.0039 0.0039
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0129 0.0666 0.0966
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Brugia malayi Heterochromatin protein 1 0.0221 0.1239 0.1421
Echinococcus granulosus histone acetyltransferase MYST2 0.0232 0.131 0.1903
Echinococcus granulosus bromodomain containing protein 8 0.0028 0.0039 0.0056
Schistosoma mansoni sex comb on midleg homolog 0.0204 0.1134 0.1475
Entamoeba histolytica ankyrin repeat protein, putative 0.0028 0.0039 0.0038
Schistosoma mansoni hypothetical protein 0.0073 0.0322 0.0417
Schistosoma mansoni importin beta-1 0.0032 0.0064 0.0081
Echinococcus granulosus Small ubiquitin modifier 2 0.0122 0.0626 0.0909
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.009 0.0106
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.009 0.0178
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.019 0.019
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0084 0.0388 0.0388
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0038 0.0103 0.0122
Loa Loa (eye worm) hypothetical protein 0.0096 0.046 0.0526
Toxoplasma gondii hypothetical protein 0.0029 0.0043 0.0071
Loa Loa (eye worm) acetyltransferase 0.0634 0.3811 0.4371
Giardia lamblia Sentrin 0.0122 0.0626 0.1385
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0081 0.0372 0.0372
Leishmania major acetyl-CoA synthetase, putative 0.0038 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0128 0.0661 0.0757
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0074 0.0327 0.0425
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0038 0.0103 0.0206
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0195 0.1082 0.1434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0023 0.0015
Echinococcus granulosus histone lysine methyltransferase setb 0.0221 0.1238 0.1798
Loa Loa (eye worm) hypothetical protein 0.0081 0.0369 0.0422
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0129 0.0666 0.1474
Echinococcus multilocularis Helicase RNase D C terminal, HRDC domain 0.0028 0.0038 0.0053
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Mycobacterium tuberculosis Conserved protein 0.0081 0.0369 0.0653
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.019 0.0403
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0345 0.2009 0.4015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0097 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0038 0.0036
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0041 0.0119 0.0242
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0028 0.0039 0.0063
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0031 0.0045
Trichomonas vaginalis bromodomain containing protein, putative 0.0028 0.0039 0.0038
Leishmania major hypothetical protein, conserved 0.0028 0.0039 0.0039
Schistosoma mansoni bromodomain containing 0.0028 0.0039 0.005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0101 0.0492 0.1082
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.1103 0.1463
Trichomonas vaginalis set domain proteins, putative 0.1016 0.6189 0.8275
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Entamoeba histolytica hypothetical protein 0.0073 0.0322 0.0416
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Schistosoma mansoni phosphoglycerate kinase 0.0737 0.445 0.5793
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0028 0.0039 0.0038
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0322 0.0466
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0194 0.1071 0.1556
Plasmodium falciparum heterochromatin protein 1 0.0036 0.009 0.0178
Mycobacterium ulcerans acyl-CoA synthetase 0.0128 0.0661 0.1217
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0771 0.4662 0.4662
Schistosoma mansoni methyl-cpg binding protein mbd 0.0092 0.0438 0.0568
Loa Loa (eye worm) mbt repeat family protein 0.0204 0.1134 0.13
Mycobacterium ulcerans 6-phosphofructokinase 0.0345 0.2009 0.3824
Loa Loa (eye worm) hypothetical protein 0.0221 0.1238 0.1419
Brugia malayi MH2 domain containing protein 0.0261 0.1488 0.1706
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0195 0.1082 0.2412
Onchocerca volvulus Huntingtin homolog 0.013 0.0676 0.0733
Echinococcus multilocularis histone acetyltransferase MYST2 0.0232 0.131 0.1903
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0128 0.0661 0.1217
Brugia malayi hypothetical protein 0.0073 0.0322 0.0368
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0036 0.009 0.0178
Brugia malayi 6-phosphofructokinase 0.0345 0.2009 0.2304
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Echinococcus multilocularis beta LACTamase domain containing family member 0.0081 0.0369 0.0534
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0197 0.1094 0.1589
Echinococcus granulosus dnaJ subfamily B 0.0427 0.2521 0.3663
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0157 0.0203
Schistosoma mansoni polybromo-1 0.0028 0.0039 0.005
Onchocerca volvulus 0.0165 0.0891 0.0981
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0029 0.0043 0.0004
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0098 0.0094
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0011 0.0012
Mycobacterium ulcerans phosphoglycerate kinase 0.0737 0.445 0.8544
Echinococcus multilocularis dna polymerase eta 0.0398 0.2344 0.3406
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.009 0.0106
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0038 0.0103 0.0147
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0356 0.208 0.208
Mycobacterium ulcerans acyl-CoA synthetase 0.0038 0.0099 0.0131
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0195 0.1082 0.2412
Loa Loa (eye worm) hypothetical protein 0.0081 0.0369 0.0422
Toxoplasma gondii bromodomain-containing protein 0.0028 0.0039 0.0063
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.034 0.1983 0.2273
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0157 0.0154
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0157 0.0195
Schistosoma mansoni ap endonuclease 0.0081 0.0372 0.0482
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0081 0.0372 0.0539
Giardia lamblia Flap structure-specific endonuclease 0.0084 0.0388 0.0848
Mycobacterium ulcerans acyl-CoA synthetase 0.0038 0.0099 0.0131
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0097 0.0468 0.1028
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0324 0.1879 0.3572
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0204 0.1134 0.1475
Brugia malayi jmjC domain containing protein 0.0074 0.0327 0.0374
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.027 0.1548 0.1548
Echinococcus multilocularis PH interacting protein 0.0028 0.0039 0.0056
Onchocerca volvulus 0.0036 0.009 0.0058
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.027 0.1548 0.1548
Loa Loa (eye worm) hypothetical protein 0.0081 0.0369 0.0422
Mycobacterium ulcerans acyl-CoA synthetase 0.0038 0.0099 0.0131
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0737 0.445 0.445
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Brugia malayi Bromodomain containing protein 0.0028 0.0039 0.0044
Entamoeba histolytica bromodomain-containing protein 0.0028 0.0039 0.0038
Trypanosoma brucei DNA polymerase eta, putative 0.0398 0.2344 0.2341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.013 0.0676 0.0774
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0081 0.0372 0.0658
Loa Loa (eye worm) hypothetical protein 0.0672 0.4046 0.464
Plasmodium vivax hypothetical protein, conserved 0.0081 0.0369 0.0805
Toxoplasma gondii ImpB/MucB/SamB family protein 0.02 0.1108 0.247
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0081 0.0369 0.0653
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0048 0.0165 0.0238
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0157 0.0195
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.1103 0.1463
Loa Loa (eye worm) inositol-1 0.0043 0.0131 0.0149
Brugia malayi RNA binding protein 0.0268 0.1531 0.1755
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0339 0.1974 0.2869
Plasmodium falciparum DNA repair protein REV1, putative 0.0089 0.0422 0.0924
Schistosoma mansoni dishevelled 0.0029 0.0043 0.0054
Brugia malayi glutaminase DH11.1 0.0608 0.3647 0.4182
Schistosoma mansoni chromobox protein 0.0036 0.009 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.004 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0036 0.009 0.0129
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0356 0.208 0.2772
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Schistosoma mansoni hypothetical protein 0.0028 0.0039 0.005
Loa Loa (eye worm) runx1 0.0178 0.0976 0.1118
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0128 0.0661 0.1217
Onchocerca volvulus 0.0081 0.0369 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Plasmodium falciparum bromodomain protein 2, putative 0.0028 0.0039 0.0063
Echinococcus granulosus histone acetyltransferase KAT2B 0.0195 0.1082 0.1571
Trypanosoma cruzi DNA damage repair protein, putative 0.0089 0.0422 0.0422
Echinococcus multilocularis chromobox protein 1 0.0221 0.1239 0.18
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0081 0.0369 0.0479
Mycobacterium ulcerans acyl-CoA synthetase 0.0038 0.0099 0.0131
Echinococcus multilocularis chromobox protein 1 0.0221 0.1239 0.18
Trypanosoma brucei DNA polymerase kappa, putative 0.0431 0.255 0.2547
Brugia malayi SET domain containing protein 0.0042 0.0124 0.014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0102
Brugia malayi mbt repeat family protein 0.0204 0.1134 0.13
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0038 0.0099 0.0138
Giardia lamblia Phosphoglycerate kinase 0.0737 0.445 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0604 0.3624 0.5267
Leishmania major small ubiquitin protein, putative 0.0122 0.0626 0.0626
Loa Loa (eye worm) jmjC domain-containing protein 0.0257 0.1467 0.1681
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0038 0.0099 0.0131
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0229 0.129 0.129
Mycobacterium tuberculosis Probable esterase LipL 0.0081 0.0369 0.0653
Schistosoma mansoni DNA helicase recq5 0.0197 0.1094 0.1423
Trypanosoma cruzi DNA polymerase kappa, putative 0.0431 0.255 0.255
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Echinococcus granulosus Pleckstrin G protein interacting region 0.0029 0.0043 0.0061
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.009 0.0116
Onchocerca volvulus 0.0081 0.0369 0.0379
Loa Loa (eye worm) phosphofructokinase 0.0345 0.2009 0.2304
Trichomonas vaginalis bromodomain containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Echinococcus granulosus PH interacting protein 0.0028 0.0039 0.0056
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0128 0.0661 0.1217
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0227 0.029
Schistosoma mansoni jumonji domain containing protein 0.0452 0.2677 0.3484
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trypanosoma brucei polo-like protein kinase 0.0199 0.1103 0.1101
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0194 0.1071 0.1556
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0092 0.0438 0.0634
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0128 0.0661 0.1412
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0478 0.0625
Brugia malayi Pre-SET motif family protein 0.0893 0.5422 0.6218
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0028 0.0039 0.0056
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0074 0.0327 0.0327
Schistosoma mansoni phosphatidylserine receptor 0.0074 0.0327 0.0425
Brugia malayi 6-phosphofructokinase 0.0345 0.2009 0.2304
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Echinococcus multilocularis segment polarity protein dishevelled 0.0029 0.0043 0.0061
Onchocerca volvulus 0.0204 0.1134 0.1261
Echinococcus granulosus SAM and MBT domain containing protein 0.0204 0.1134 0.1647
Leishmania major hypothetical protein, conserved 0.0074 0.0327 0.0327
Schistosoma mansoni CREB-binding protein 2 0.0028 0.0039 0.005
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0026 0.002
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0074 0.0327 0.0327
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Loa Loa (eye worm) TAR-binding protein 0.0268 0.1531 0.1755
Echinococcus multilocularis phosphoglycerate kinase 1 0.0737 0.445 0.6469
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.0044
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0199 0.1104 0.2461
Onchocerca volvulus 0.0038 0.0099 0.0068
Brugia malayi jmjC domain containing protein 0.0074 0.0327 0.0374
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0081 0.0372 0.0372
Schistosoma mansoni hypothetical protein 0.0036 0.009 0.0116
Plasmodium falciparum phd finger protein, putative 0.0125 0.0641 0.1418
Trichomonas vaginalis esterase, putative 0.0081 0.0369 0.0479
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0038 0.0099 0.0142
Toxoplasma gondii hypothetical protein 0.0263 0.15 0.3353
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0026 0.0026
Trypanosoma cruzi ISWI complex protein 0.0082 0.0379 0.0379
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0288 0.1658 0.19
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0086 0.0402 0.0583
Echinococcus multilocularis peregrin 0.0153 0.0815 0.1183
Brugia malayi regulator of G-protein signaling egl-10 0.005 0.0175 0.0199
Schistosoma mansoni z-protein (S1r protein) 0.005 0.0175 0.0226
Schistosoma mansoni dishevelled 0.0029 0.0043 0.0054
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Brugia malayi Importin beta-1 subunit 0.0032 0.0064 0.0072
Echinococcus granulosus Bromodomain containing protein 0.0028 0.0039 0.0056
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Schistosoma mansoni hypothetical protein 0.0367 0.2152 0.28
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0028 0.0039 0.0038
Brugia malayi hypothetical protein 0.0097 0.0472 0.054
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0103 0.0509 0.0509
Mycobacterium tuberculosis Conserved hypothetical alanine rich protein 0.0028 0.0038 0.0013
Trypanosoma cruzi Bromodomain, putative 0.0028 0.0039 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0023 0.0015
Echinococcus multilocularis jumonji domain containing 1A 0.0074 0.0327 0.0474
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0345 0.2009 0.2009
Brugia malayi PHD-finger family protein 0.0125 0.0641 0.0734
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0517 0.3082 0.5898
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Schistosoma mansoni terminal deoxycytidyl transferase 0.0288 0.1658 0.2157
Loa Loa (eye worm) hypothetical protein 0.0096 0.046 0.0526
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0093 0.0445 0.0976
Trypanosoma brucei phosphoglycerate kinase 0.0737 0.445 0.4449
Trypanosoma brucei ISWI complex protein 0.0082 0.0379 0.0376
Entamoeba histolytica hypothetical protein 0.0073 0.0322 0.0416
Toxoplasma gondii bromodomain-containing protein 0.0028 0.0039 0.0063
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0028 0.0039 0.0063
Brugia malayi Phosphoglycerate kinase 0.0737 0.445 0.5104
Loa Loa (eye worm) hypothetical protein 0.0097 0.0469 0.0537
Giardia lamblia Sgs1 DNA helicase, putative 0.0197 0.1094 0.2439
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0157 0.0195
Schistosoma mansoni 6-phosphofructokinase 0.0345 0.2009 0.2614
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.1103 0.1463
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0157 0.0195
Mycobacterium tuberculosis Probable lipase LipE 0.0081 0.0369 0.0653
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0224 0.126 0.126
Schistosoma mansoni tar DNA-binding protein 0.0268 0.1531 0.1992
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1629 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0636 0.0836
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0081 0.0372 0.0812
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0195 0.1082 0.2412
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0055 0.0058
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0041 0.0119 0.0116
Brugia malayi Bromodomain containing protein 0.0028 0.0039 0.0044
Brugia malayi Bromodomain containing protein 0.0222 0.1245 0.1427
Echinococcus multilocularis geminin 0.0367 0.2152 0.3127
Brugia malayi ImpB/MucB/SamB family protein 0.0398 0.2344 0.2687
Brugia malayi jmjC domain containing protein 0.0074 0.0327 0.0374
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.1103 0.1463
Schistosoma mansoni phd/f-box containing protein 0.0074 0.0327 0.0425
Echinococcus multilocularis Bromodomain containing protein 0.0028 0.0039 0.0056
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0064 0.0091
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.009 0.0116
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0038 0.0099 0.0131
Echinococcus granulosus peregrin 0.0153 0.0815 0.1183
Mycobacterium ulcerans DNA polymerase IV 0.0431 0.255 0.487
Echinococcus multilocularis chromobox protein 2 0.0036 0.009 0.0129
Schistosoma mansoni hypothetical protein 0.0111 0.0558 0.0725
Brugia malayi Bloom's syndrome protein homolog 0.0326 0.1896 0.2174
Echinococcus multilocularis snurportin 1 0.034 0.1983 0.2881
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0096 0.046 0.0829
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0339 0.1974 0.2869
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0486 0.2893 0.3317
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0038 0.0099 0.0112
Echinococcus granulosus tumor protein p63 0.1127 0.6879 1
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0038 0.0099 0.0197
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0082 0.016
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0101 0.0492 0.0492
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0131 0.0131
Onchocerca volvulus 0.1016 0.6189 0.7085
Trypanosoma brucei phosphoglycerate kinase 0.027 0.1548 0.1546
Brugia malayi AMP-binding enzyme family protein 0.0038 0.0099 0.0112
Loa Loa (eye worm) hypothetical protein 0.1423 0.8718 1
Brugia malayi hypothetical protein 0.0486 0.2893 0.3317
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.027 0.1548 0.1548
Schistosoma mansoni microtubule-associated protein tau 0.0715 0.4314 0.5615
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0064 0.0072
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0028 0.0039 0.0038
Brugia malayi ImpB/MucB/SamB family protein 0.0288 0.1658 0.19
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0199 0.1103 0.1603
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0028 0.0039 0.005
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0093 0.0445 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0031 0.0027
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0324 0.1879 0.1879
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0093 0.0445 0.0976
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.03 0.173 0.3872
Trypanosoma brucei DNA polymerase kappa, putative 0.0234 0.1323 0.132
Trypanosoma cruzi small ubiquitin protein, putative 0.0122 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0081 0.0369 0.0422
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0356 0.208 0.3023
Echinococcus multilocularis regulator of G protein signaling 7 0.005 0.0175 0.0252
Loa Loa (eye worm) glutaminase 2 0.0608 0.3647 0.4182
Onchocerca volvulus 0.0038 0.0099 0.0068
Echinococcus granulosus phd:f box containing protein 0.0074 0.0327 0.0474
Schistosoma mansoni tar DNA-binding protein 0.0268 0.1531 0.1992
Brugia malayi F/Y-rich N-terminus family protein 0.0065 0.0269 0.0307
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.1103 0.1463
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trypanosoma brucei phosphoglycerate kinase, putative 0.027 0.1548 0.1546
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0199 0.1103 0.1103
Loa Loa (eye worm) translation initiation factor 4E 0.0038 0.0103 0.0116
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0081 0.0372 0.0372
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.009 0.0106
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0038 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0113 0.0136
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0123 0.0632 0.0822
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0038 0.0099 0.0131
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.1223 0.7476 1
Trypanosoma cruzi ISWI complex protein 0.0082 0.0379 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0038 0.0036
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0356 0.208 0.2707
Trypanosoma brucei DNA polymerase kappa, putative 0.0431 0.255 0.2547
Trypanosoma brucei DNA damage repair protein, putative 0.0089 0.0422 0.0418
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.1103 0.1435
Echinococcus multilocularis expressed protein 0.0106 0.0524 0.076
Brugia malayi jmjC domain containing protein 0.029 0.1673 0.1917
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0081 0.0372 0.0539
Loa Loa (eye worm) MH2 domain-containing protein 0.0261 0.1488 0.1706
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0081 0.0372 0.0698
Echinococcus granulosus expressed protein 0.0413 0.2433 0.3536
Echinococcus granulosus beta LACTamase domain containing family member 0.0081 0.0369 0.0534
Echinococcus multilocularis Chromo domain 0.0036 0.009 0.0129
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.009 0.0106
Trypanosoma brucei DNA polymerase kappa, putative 0.0234 0.1323 0.132
Trichomonas vaginalis chromobox protein, putative 0.0036 0.009 0.0106
Loa Loa (eye worm) SMO-1 protein 0.0122 0.0626 0.0717
Trypanosoma cruzi DNA polymerase eta, putative 0.02 0.1108 0.1108
Trypanosoma brucei DNA polymerase kappa, putative 0.0431 0.255 0.2547
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0131 0.0161
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0038 0.0099 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Mycobacterium leprae conserved hypothetical protein 0.0081 0.0369 0.075
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0066 0.0066
Leishmania major 4-coumarate:coa ligase-like protein 0.0128 0.0661 0.0661
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trypanosoma brucei DNA polymerase IV, putative 0.0431 0.255 0.2547
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0411 0.0535
Loa Loa (eye worm) hypothetical protein 0.0081 0.0369 0.0422
Entamoeba histolytica ubiquitin like protein 0.0122 0.0626 0.0824
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0157 0.0227
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1629 1 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.019 0.0217
Schistosoma mansoni bromodomain containing protein 0.0358 0.2094 0.2725
Loa Loa (eye worm) DIX domain-containing protein 0.0029 0.0043 0.0048
Giardia lamblia DNA damage repair protein 0.0089 0.0422 0.0924
Brugia malayi TAR-binding protein 0.0268 0.1531 0.1755
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0038 0.0099 0.0197
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0536 0.3199 0.465
Echinococcus granulosus segment polarity protein dishevelled 0.0029 0.0043 0.0061
Plasmodium falciparum small ubiquitin-related modifier 0.0122 0.0626 0.1385
Trypanosoma brucei unspecified product 0.0199 0.1101 0.1098
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0081 0.0372 0.0812
Toxoplasma gondii PHD-finger domain-containing protein 0.0041 0.0119 0.0242
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0133 0.069 0.1002
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0131 0.0128
Trypanosoma brucei Bromodomain, putative 0.0028 0.0039 0.0036
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0089 0.0422 0.0924
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0232 0.131 0.1903
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Onchocerca volvulus Alhambra homolog 0.0125 0.0641 0.0693
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0197 0.1094 0.2439
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0132 0.0162
Brugia malayi beta-lactamase family protein 0.0081 0.0369 0.0422
Loa Loa (eye worm) RNA binding protein 0.0268 0.1531 0.1755
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.029 0.0376
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0038 0.0099 0.0131
Echinococcus multilocularis flap endonuclease 1 0.0084 0.0388 0.0562
Plasmodium vivax importin-beta 2, putative 0.0032 0.0064 0.0118
Onchocerca volvulus 0.0165 0.0892 0.0982
Echinococcus granulosus global transcription activator snf2l2 0.0028 0.0039 0.0056
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0536 0.3199 0.465
Toxoplasma gondii histone lysine methyltransferase SET1 0.0089 0.0422 0.0925
Trypanosoma brucei unspecified product 0.0199 0.1101 0.1098
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0064 0.006
Mycobacterium tuberculosis Conserved protein 0.0081 0.0369 0.0653
Echinococcus granulosus geminin 0.0367 0.2152 0.3127
Brugia malayi hypothetical protein 0.0036 0.009 0.0102
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0029 0.0043 0.0048
Giardia lamblia Histone acetyltransferase GCN5 0.0167 0.0908 0.2019
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0099 0.0131
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Entamoeba histolytica bromodomain-containing protein 0.0028 0.0039 0.0038
Trichomonas vaginalis phosphofructokinase, putative 0.0093 0.0445 0.058
Schistosoma mansoni myelin transcription factor 1 myt1 0.0232 0.131 0.1704
Schistosoma mansoni phosphoglycerate kinase 0.0737 0.445 0.5793
Entamoeba histolytica exosome component 10, putative 0.0028 0.0038 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0096 0.046 0.0526
Giardia lamblia Transcription regulatory protein SNF2 0.0028 0.0039 0.0063
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0038 0.0103 0.0099
Loa Loa (eye worm) CHromoDomain protein family member 0.0048 0.0165 0.0188
Echinococcus multilocularis transcription factor Dp 1 0.0206 0.1148 0.1667
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0081 0.0369 0.0653
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0039 0.0038
Echinococcus granulosus CREB binding protein 0.0028 0.0039 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0097 0.0115
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0229 0.129 0.129
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0038 0.0103 0.0122
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0133 0.069 0.0791
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0197 0.1094 0.1254
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0131 0.0161
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0221 0.1238 0.161
Loa Loa (eye worm) hypothetical protein 0.0074 0.0327 0.0374
Brugia malayi chromobox protein homolog 3 0.0124 0.0636 0.0728
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0038 0.0099 0.0131
Schistosoma mansoni ran 0.0023 0.0011 0.0013
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0074 0.0327 0.0712
Echinococcus multilocularis PHD finger protein rhinoceros 0.0125 0.0641 0.093
Treponema pallidum phosphoglycerate kinase 0.0737 0.445 1
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0327 0.0425
Trypanosoma brucei DNA polymerase kappa, putative 0.0324 0.1879 0.1876
Plasmodium vivax hypothetical protein, conserved 0.0043 0.013 0.0268
Trypanosoma cruzi Bromodomain, putative 0.0028 0.0039 0.0039
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0427 0.0766
Trichomonas vaginalis antibiotic synthetase, putative 0.0038 0.0099 0.0117
Entamoeba histolytica hypothetical protein 0.0073 0.0322 0.0416
Echinococcus multilocularis expressed protein 0.0413 0.2433 0.3536
Echinococcus granulosus bromodomain containing 2 0.0028 0.0039 0.0056
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.009 0.0106
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0122 0.0626 0.0814
Echinococcus granulosus snurportin 1 0.034 0.1983 0.2881
Schistosoma mansoni helicase 0.0028 0.0039 0.005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0858 0.5204 1
Schistosoma mansoni tar DNA-binding protein 0.0268 0.1531 0.1992
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0028 0.0039 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0097 0.0115
Echinococcus granulosus expressed protein 0.0106 0.0524 0.076
Trypanosoma brucei Bromodomain, putative 0.0028 0.0039 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0082 0.0095
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.0131 0.015
Toxoplasma gondii peptidylprolyl isomerase 0.0103 0.0509 0.112
Entamoeba histolytica phosphofructokinase, putative 0.0345 0.2009 0.2676

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 3 uM Inhibition of human HCT116 cells ChEMBL. 17705462
IC50 (functional) = 3 uM Inhibition of human A431 cells ChEMBL. 17705462

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 17705462

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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