Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.7016 | 0.7016 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0438 | 0.0438 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.4263 | 0.4263 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.7016 | 0.4799 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.7016 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.7016 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.4263 | 0.4263 |
Onchocerca volvulus | 0.0026 | 0.4263 | 0.5 | |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.4263 | 0.4263 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.7016 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.4113 | 0.4113 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0026 | 0.4263 | 0.4263 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.7016 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 1 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.4263 | 0.4001 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.4263 | 0.4001 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.7016 | 0.4799 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.7016 | 0.7016 |
Echinococcus granulosus | lamin | 0.0026 | 0.4263 | 0.4263 |
Onchocerca volvulus | 0.0026 | 0.4263 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0035 | 0.7016 | 0.688 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.4263 | 0.4263 |
Echinococcus multilocularis | lamin | 0.0026 | 0.4263 | 0.4263 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.4263 | 0.4263 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.4263 | 0.4263 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.