Detailed information for compound 1141416

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 310.433 | Formula: C20H26N2O
  • H donors: 0 H acceptors: 0 LogP: 3.49 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CO[C@H]1C[C@]2(CC)CCCN3[C@@H]2c2n1c1ccccc1c2CC3
  • InChi: 1S/C20H26N2O/c1-3-20-10-6-11-21-12-9-15-14-7-4-5-8-16(14)22(17(13-20)23-2)18(15)19(20)21/h4-5,7-8,17,19H,3,6,9-13H2,1-2H3/t17-,19+,20-/m0/s1
  • InChiKey: BVWWUWXMEWKEMC-SXLOBPIMSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus histone acetyltransferase MYST2 0.0063 0.0078 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0034 0.0034
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0026 0.0021 0.0017
Echinococcus multilocularis tensin 0.0027 0.0022 0.0018
Trypanosoma cruzi fatty acid desaturase, putative 0.0057 0.0069 0.0065
Echinococcus multilocularis polycomb protein SCMH1 0.0055 0.0066 0.0062
Schistosoma mansoni formin binding protein and related proteins 0.0026 0.0021 0.0017
Trypanosoma brucei fatty acid desaturase, putative 0.0072 0.0092 0.0088
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Onchocerca volvulus 0.0072 0.0092 0.374
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0061 0.0074 0.007
Schistosoma mansoni tyrosine kinase 0.0034 0.0034 0.003
Schistosoma mansoni myelin transcription factor 1 myt1 0.0063 0.0078 0.0074
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0006 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0021 0.0287
Entamoeba histolytica BAR/SH3 domain containing protein 0.0026 0.0021 0.0374
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0008 0.0004
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0052 0.0048
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.001 0.0256
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0006 0.0235
Brugia malayi Protein kinase domain containing protein 0.0034 0.0034 0.0034
Schistosoma mansoni nck2/grb4 0.0053 0.0062 0.0058
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0043 0.1037
Echinococcus multilocularis SAM and MBT domain containing protein 0.0055 0.0066 0.0062
Schistosoma mansoni C-fyn 0.0026 0.0021 0.0017
Schistosoma mansoni growth factor receptor-bound protein 0.0053 0.0062 0.0058
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0022 0.073
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0061 0.0074 0.007
Onchocerca volvulus 0.0026 0.0021 0.0853
Echinococcus granulosus geminin 0.0362 0.0538 0.0534
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0035 0.0034 0.0034
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0026 0.0021 0.0017
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0035 0.0034 0.0034
Brugia malayi SH2 domain containing protein 0.0034 0.0034 0.0034
Schistosoma mansoni nuclear receptor 0.0016 0.0006 0.0002
Loa Loa (eye worm) SH2 domain-containing protein 0.0027 0.0022 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0035 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Trypanosoma cruzi fatty acid desaturase, putative 0.0072 0.0092 0.0088
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0035 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Brugia malayi nuclear hormone receptor family member nhr-6 0.0016 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0035 0.0034 0.0034
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0034 0.0034 0.003
Echinococcus granulosus Protein patched homolog 1 0.0089 0.0117 0.0113
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0034 0.0034 0.003
Echinococcus multilocularis dihydrofolate reductase 0.0043 0.0046 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0035 0.0034 0.0034
Leishmania major hypothetical protein, conserved 0.0056 0.0067 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0247 0.6291
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0043 0.0046 0.1745
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0035 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0058 0.007 0.007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.001 0.0006
Schistosoma mansoni dynamin-associated protein 0.0026 0.0021 0.0017
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0055 0.0066 0.2672
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0072 0.0068
Entamoeba histolytica protein kinase, putative 0.0026 0.0021 0.0374
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0387 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0034 0.0034
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0043 0.0046 0.1137
Echinococcus granulosus cpg binding protein 0.0034 0.0034 0.003
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0022 0.0399
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0021 0.0021
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0008 0.0004
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0035 0.0034 0.003
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0009 0.0005
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0328 0.0486 0.0482
Echinococcus granulosus c src tyrosine kinase 0.0061 0.0074 0.007
Brugia malayi protein-tyrosine kinase 0.0034 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Echinococcus granulosus tyrosine protein kinase Fyn 0.0061 0.0074 0.007
Onchocerca volvulus Protein ultraspiracle homolog 0.0035 0.0034 0.1372
Leishmania major hypothetical protein, conserved 0.004 0.0043 0.0039
Echinococcus granulosus tyrosine protein kinase Blk 0.0034 0.0034 0.003
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.6503 1 1
Schistosoma mansoni survival motor neuron protein 0.0047 0.0053 0.0049
Schistosoma mansoni tensin-related 0.0027 0.0022 0.0018
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0911 0.1385 0.1382
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0027 0.0022 0.0018
Echinococcus granulosus tyrosine protein kinase Fyn 0.0061 0.0074 0.007
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0105 0.0142 0.3698
Brugia malayi beta-lactamase 0.004 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0027 0.0022 0.0018
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0043 0.0861
Onchocerca volvulus 0.0026 0.0021 0.0853
Schistosoma mansoni vav2 0.0027 0.0022 0.0018
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0027 0.0022 0.0018
Onchocerca volvulus 0.0026 0.0021 0.0853
Brugia malayi Protein kinase domain containing protein 0.0034 0.0034 0.0034
Plasmodium vivax ataxin-2 like protein, putative 0.0056 0.0067 0.3218
Brugia malayi Dihydrofolate reductase 0.0043 0.0046 0.0046
Mycobacterium tuberculosis Conserved protein 0.004 0.0043 0.1037
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0022 0.0399
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0021 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0117 0.2844
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Echinococcus granulosus Niemann Pick C1 protein 0.0295 0.0435 0.0432
Brugia malayi dihydrofolate reductase family protein 0.0043 0.0046 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0035 0.0034 0.0034
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0006 0.0002
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.001 0.001
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Brugia malayi Sex muscle abnormal protein 5 0.0053 0.0062 0.0062
Onchocerca volvulus 0.0027 0.0022 0.0894
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0035 0.0034 0.003
Onchocerca volvulus Glucosylceramidase homolog 0.0173 0.0247 1
Echinococcus granulosus expressed conserved protein 0.0194 0.028 0.0276
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0261 0.6672
Brugia malayi tailless protein 0.0016 0.0006 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0034 0.003
Echinococcus granulosus Niemann Pick C1 protein 0.0207 0.0299 0.0295
Onchocerca volvulus 0.0016 0.0006 0.0235
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0061 0.0074 0.007
Echinococcus granulosus dihydrofolate reductase 0.0043 0.0046 0.0042
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0027 0.0022 0.0018
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0022 0.073
Loa Loa (eye worm) mbt repeat family protein 0.0055 0.0066 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0043 0.0039
Echinococcus granulosus SH2 domain containing adapter protein F 0.0027 0.0022 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0021 0.0017
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0328 0.0486 0.0482
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0011 0.0549
Loa Loa (eye worm) hypothetical protein 0.0035 0.0034 0.0034
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0043 0.0043
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0011 0.0303
Entamoeba histolytica hypothetical protein 0.004 0.0043 0.1135
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0063 0.0078 0.0074
Schistosoma mansoni nuclear receptor 0.0016 0.0006 0.0002
Brugia malayi CXXC zinc finger family protein 0.0032 0.0031 0.0031
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0027 0.0022 0.0022
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0026 0.0021 0.0017
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0105 0.0142 0.0138
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0006 0.0002
Onchocerca volvulus 0.0105 0.0142 0.5742
Onchocerca volvulus 0.0027 0.0022 0.0894
Trypanosoma brucei fructose-1,6-bisphosphatase 0.6503 1 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0155 0.022 0.0216
Onchocerca volvulus 0.004 0.0043 0.1728
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0009
Schistosoma mansoni cpg binding protein 0.0034 0.0034 0.003
Echinococcus granulosus tyrosine protein kinase Fyn 0.0061 0.0074 0.007
Onchocerca volvulus 0.0072 0.0092 0.374
Leishmania major stearic acid desaturase, putative 0.0072 0.0092 0.0088
Loa Loa (eye worm) hypothetical protein 0.0035 0.0034 0.0034
Mycobacterium ulcerans thymidylate synthase 0.0105 0.0142 0.5677
Loa Loa (eye worm) hypothetical protein 0.004 0.0043 0.0043
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0008 0.0004
Echinococcus granulosus tyrosine protein kinase Src42A 0.0027 0.0022 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0247 0.6291
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0034 0.0034
Brugia malayi nuclear receptor RXR 0.0016 0.0006 0.0006
Brugia malayi SH2 domain containing protein 0.0027 0.0022 0.0022
Trichomonas vaginalis p67phox protein, putative 0.0026 0.0021 0.0287
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0035 0.0034 0.003
Brugia malayi cytokine inducible SH2-containing protein 5 0.0027 0.0022 0.0022
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0043 0.0039
Loa Loa (eye worm) hypothetical protein 0.0035 0.0034 0.0034
Brugia malayi SH2 domain containing protein 0.0034 0.0034 0.0034
Mycobacterium ulcerans hypothetical protein 0.0027 0.0022 0.073
Schistosoma mansoni Dab2-interacting protein-like 0.0026 0.0021 0.0017
Onchocerca volvulus 0.0027 0.0022 0.0894
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0043 0.1037
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0034 0.0034
Mycobacterium tuberculosis Hypothetical protein 0.005 0.0057 0.1431
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0043 0.0043
Schistosoma mansoni steroid hormone receptor ad4bp 0.0035 0.0034 0.003
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0022 0.073
Schistosoma mansoni growth factor receptor-bound protein 0.0053 0.0062 0.0058
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0072 0.1818
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Echinococcus granulosus SHC transforming protein 3 0.0027 0.0022 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0193 0.0277 0.0273
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0035 0.0034 0.003
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0147 0.0208 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0263 0.0387 0.0387
Schistosoma mansoni dihydrofolate reductase 0.0043 0.0046 0.0042
Echinococcus multilocularis protein patched 0.0089 0.0117 0.0113
Brugia malayi Src substrate cortactin 0.0026 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0035 0.0034 0.0034
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0043 0.0039
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0043 0.0861
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0027 0.0022 0.0022
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0061 0.0074 0.007
Brugia malayi RhoGAP domain containing protein 0.0027 0.0022 0.0022
Loa Loa (eye worm) SRC-1 0.0061 0.0074 0.0074
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0034 0.0034 0.0812
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0006 0.0235
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0009 0.0005
Echinococcus multilocularis N chimaerin 0.0027 0.0022 0.0018
Brugia malayi Spectrin alpha chain 0.0026 0.0021 0.0021
Echinococcus granulosus Spectrin alpha actinin 0.0026 0.0021 0.0017
Schistosoma mansoni hypothetical protein 0.0018 0.0009 0.0005
Mycobacterium leprae Probable lipase LipE 0.004 0.0043 0.1741
Brugia malayi hypothetical protein 0.0036 0.0036 0.0036
Echinococcus multilocularis tyrosine protein kinase Abl 0.0061 0.0074 0.007
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0076 0.0076
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0034 0.0034
Brugia malayi nuclear hormone receptor 0.0035 0.0034 0.0034
Entamoeba histolytica hypothetical protein 0.0026 0.0021 0.0374
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.001 0.5
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0043 0.0039
Brugia malayi beta-lactamase family protein 0.004 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0027 0.0022 0.0018
Echinococcus multilocularis SH2 motif 0.0027 0.0022 0.0018
Loa Loa (eye worm) fatty acid desaturase 0.0015 0.0004 0.0004
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0009 0.0005
Entamoeba histolytica BAR/SH3 domain containing protein 0.0026 0.0021 0.0374
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0035 0.0034 0.0034
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0034 0.003
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.001 0.5
Echinococcus multilocularis tensin 0.0027 0.0022 0.0018
Onchocerca volvulus 0.0047 0.0053 0.2148
Entamoeba histolytica hypothetical protein 0.004 0.0043 0.1135
Loa Loa (eye worm) hypothetical protein 0.0109 0.0148 0.0148
Echinococcus multilocularis nostrin 0.0026 0.0021 0.0017
Toxoplasma gondii hypothetical protein 0.0053 0.0062 0.0062
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.001 0.5
Plasmodium falciparum stearoyl-CoA desaturase 0.0057 0.0069 0.3327
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0034 0.0034 0.003
Loa Loa (eye worm) thymidylate synthase 0.0105 0.0142 0.0142
Echinococcus granulosus tyrosine protein kinase Src42A 0.0061 0.0074 0.007
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0008 0.0004
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0089 0.0117 0.0117
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0105 0.0142 1
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0021 0.0017
Echinococcus multilocularis 0.0027 0.0022 0.0018
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0193 0.0277 0.0277
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0053 0.0053
Echinococcus multilocularis tyrosine protein kinase Srms 0.0034 0.0034 0.003
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0008 0.0004
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0021 0.0021
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0008 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0247 0.6291
Echinococcus multilocularis dnaJ subfamily B 0.0463 0.0694 0.069
Brugia malayi mbt repeat family protein 0.0055 0.0066 0.0066
Onchocerca volvulus 0.0034 0.0034 0.1365
Echinococcus multilocularis cpg binding protein 0.0034 0.0034 0.003
Schistosoma mansoni niemann-pick C1 (NPC1) 0.021 0.0304 0.03
Echinococcus granulosus tyrosine protein kinase Src64B 0.0061 0.0074 0.007
Loa Loa (eye worm) thyroid receptor interactor 0.0026 0.0021 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0043 0.0039
Schistosoma mansoni SH2A 0.0027 0.0022 0.0018
Loa Loa (eye worm) TK protein kinase 0.0034 0.0034 0.0034
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0034 0.003
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0027 0.0022 0.041
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0027 0.0022 0.0022
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0026 0.0021 0.0853
Onchocerca volvulus 0.0026 0.0021 0.0853
Mycobacterium ulcerans beta-lactamase 0.004 0.0043 0.1592
Echinococcus granulosus survival motor neuron protein 1 0.023 0.0335 0.0332
Loa Loa (eye worm) STAT protein 0.0027 0.0022 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0072 0.2792
Echinococcus granulosus SH2 domain containing protein 7 0.0027 0.0022 0.0018
Mycobacterium tuberculosis Conserved protein 0.004 0.0043 0.1037
Brugia malayi SH2 domain containing protein 0.0027 0.0022 0.0022
Schistosoma mansoni run and tbc1 domain containing 0.0026 0.0021 0.0017
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0021 0.0021
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0061 0.0074 0.007
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0043 0.0039
Loa Loa (eye worm) hypothetical protein 0.004 0.0043 0.0043
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0006 0.0006
Toxoplasma gondii sphingolipid delta 4 desaturase/c-4 hydroxylase protein des2 family protein 0.0015 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0019 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0021 0.0287
Schistosoma mansoni hypothetical protein 0.0085 0.0112 0.0108
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Echinococcus multilocularis SH2 motif 0.0027 0.0022 0.0018
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0066 0.0062
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Toxoplasma gondii fructose-bisphospatase I 0.2418 0.3707 0.3707
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0043 0.1037
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0072 0.0068
Loa Loa (eye worm) hypothetical protein 0.0063 0.0078 0.0078
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0016 0.0006 0.0002
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0061 0.0074 0.007
Echinococcus granulosus tyrosine protein kinase Lyn 0.0061 0.0074 0.007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0072 0.2792
Brugia malayi Fatty acid desaturase family protein 0.0015 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.004 0.0043 0.0043
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0035 0.0034 0.003
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0034 0.0034
Brugia malayi Protein kinase domain containing protein 0.0034 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0035 0.0034 0.0034
Brugia malayi ecdysone receptor 0.0016 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0247 0.6291
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0147 0.0208 0.0208
Toxoplasma gondii ABC1 family protein 0.004 0.0043 0.0043
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0027 0.0022 0.0894
Loa Loa (eye worm) beta-lactamase 0.004 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0021 0.0287
Brugia malayi Fes/CIP4 homology domain containing protein 0.0026 0.0021 0.0021
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0263 0.0387 0.0387
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.001 0.0494
Echinococcus multilocularis sterol regulatory element binding protein 0.0089 0.0117 0.0113
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0147 0.0208 0.0204
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0022 0.073
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0034 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0022 0.073
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0033 0.0029
Schistosoma mansoni ap endonuclease 0.0019 0.001 0.0006
Echinococcus granulosus fch and double sh3 domains protein 2 0.0026 0.0021 0.0017
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0021 0.0021
Onchocerca volvulus 0.0016 0.0006 0.0235
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Brugia malayi hypothetical protein 0.0034 0.0034 0.0034
Onchocerca volvulus Putative cortactin 0.0026 0.0021 0.0853
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0247 0.6291
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0027 0.0022 0.0018
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0061 0.0074 0.007
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0222 0.0323 0.0319
Echinococcus multilocularis expressed protein 0.0026 0.0021 0.0017
Echinococcus granulosus tyrosine kinase 0.0034 0.0034 0.003
Schistosoma mansoni tyrosine kinase 0.0061 0.0074 0.007
Echinococcus granulosus tyrosine kinase 0.0034 0.0034 0.003
Echinococcus multilocularis Spectrin alpha actinin 0.0026 0.0021 0.0017
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0034 0.003
Schistosoma mansoni tyrosine kinase 0.0061 0.0074 0.007
Onchocerca volvulus 0.0027 0.0022 0.0881
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0052 0.0048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.0152
Schistosoma mansoni fructose-16-bisphosphatase-related 0.6503 1 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Schistosoma mansoni tyrosine kinase 0.0034 0.0034 0.003
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0009 0.0009
Loa Loa (eye worm) dihydrofolate reductase 0.0043 0.0046 0.0046
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0193 0.0277 0.0273
Schistosoma mansoni hypothetical protein 0.0085 0.0112 0.0108
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.6503 1 1
Brugia malayi Delta5 fatty acid desaturase 0.0015 0.0004 0.0004
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.007 0.007
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.007 0.007
Echinococcus granulosus SH2 motif 0.0027 0.0022 0.0018
Brugia malayi Fatty acid desaturase family protein 0.0015 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0026 0.0021 0.0017
Echinococcus multilocularis GPCR, family 2 0.0018 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0089 0.0117 0.0117
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0009 0.0009
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0043 0.1592
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0222 0.0323 0.0319
Echinococcus granulosus suppressor of cytokine signaling 7 0.0027 0.0022 0.0018
Entamoeba histolytica hypothetical protein 0.004 0.0043 0.1135
Entamoeba histolytica hypothetical protein 0.004 0.0043 0.1135
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0008 0.0004
Brugia malayi steroid hormone receptor 0.0035 0.0034 0.0034
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0026 0.0021 0.0017
Loa Loa (eye worm) nuclear receptor NHR-67 0.0016 0.0006 0.0006
Schistosoma mansoni tyrosine kinase 0.0061 0.0074 0.007
Brugia malayi acyl-CoA desaturase 0.0057 0.0069 0.0069
Schistosoma mansoni eps8-related protein 0.0026 0.0021 0.0017
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0009 0.0005
Loa Loa (eye worm) DR-78 0.0016 0.0006 0.0006
Schistosoma mansoni adapter molecule crk 0.0053 0.0062 0.0058
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.2418 0.3707 0.3704
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0027 0.0022 0.0018
Echinococcus granulosus growth factor receptor bound protein 2 0.0053 0.0062 0.0058
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0035 0.0034 0.003
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0016 0.0006 0.0002
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0026 0.0021 0.0017
Echinococcus multilocularis growth factor receptor bound protein 2 0.0053 0.0062 0.0058
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0034
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0043 0.0039
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Entamoeba histolytica hypothetical protein 0.0026 0.0021 0.0374
Echinococcus multilocularis protein dispatched 1 0.0101 0.0137 0.0133
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0009
Leishmania major fatty-acid desaturase, putative 0.0072 0.0092 0.0088
Entamoeba histolytica SH2 domain containing protein 0.0027 0.0022 0.041
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0022 0.0022
Entamoeba histolytica hypothetical protein, conserved 0.0026 0.0021 0.0374
Brugia malayi nuclear receptor NHR-88 0.0035 0.0034 0.0034
Toxoplasma gondii exonuclease III APE 0.0019 0.001 0.001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0035 0.0034 0.003
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0016 0.0006 0.0002
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0031 0.0031
Echinococcus multilocularis endophilin A3 0.0026 0.0021 0.0017
Schistosoma mansoni patched 1 0.0089 0.0117 0.0113
Schistosoma mansoni tensin 0.0027 0.0022 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0035 0.0034 0.0034
Brugia malayi photoreceptor-specific nuclear receptor 0.0035 0.0034 0.0034
Trypanosoma brucei conserved protein 0.0026 0.0021 0.0017
Brugia malayi nuclear hormone receptor family member odr-7 0.0016 0.0006 0.0006
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0061 0.0074 0.007
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0043 0.0039
Loa Loa (eye worm) hypothetical protein 0.004 0.0042 0.0042
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0022 0.0022
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0053 0.0062 0.0062
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0026 0.0021 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0261 0.6672
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0027 0.0022 0.0022
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0009 0.0009
Schistosoma mansoni shc transforming protein 0.0027 0.0022 0.0018
Brugia malayi STAT protein, DNA binding domain containing protein 0.0027 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0009
Echinococcus granulosus dnaJ subfamily B 0.0463 0.0694 0.069
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0019 0.0015
Brugia malayi Variant SH3 domain containing protein 0.0053 0.0062 0.0062
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0016 0.0006 0.0006
Onchocerca volvulus 0.0032 0.0031 0.1245
Echinococcus multilocularis NCK adaptor protein 0.0053 0.0062 0.0058
Brugia malayi beta-lactamase family protein 0.004 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0034 0.0034
Echinococcus multilocularis Niemann Pick C1 protein 0.0295 0.0435 0.0432
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Mycobacterium ulcerans hypothetical protein 0.0173 0.0247 1
Brugia malayi Guanylate kinase family protein 0.0026 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.034 0.0505 0.0501
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0027 0.0022 0.0018
Echinococcus granulosus ecdysone induced protein 78C 0.0035 0.0034 0.003
Schistosoma mansoni sorbin 0.0026 0.0021 0.0017
Trypanosoma brucei PAB1-binding protein , putative 0.0056 0.0067 0.0063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0193 0.0277 0.0273
Loa Loa (eye worm) hypothetical protein 0.0035 0.0034 0.0034
Loa Loa (eye worm) SH2 domain-containing protein 0.0027 0.0022 0.0022
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0043 0.0046 0.2052
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0052 0.0048
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0043 0.0861
Brugia malayi Protein kinase domain containing protein 0.0034 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Echinococcus multilocularis signal transduction protein lnk realted 0.0027 0.0022 0.0018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0035 0.0034 0.003
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0053 0.0062 0.0062
Brugia malayi hypothetical protein 0.004 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0021 0.0287
Brugia malayi hypothetical protein 0.0018 0.0009 0.0009
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0147 0.0208 0.0204
Brugia malayi Myosin tail family protein 0.0026 0.0021 0.0021
Echinococcus multilocularis geminin 0.0362 0.0538 0.0534
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0021 0.0287
Plasmodium vivax hypothetical protein, conserved 0.004 0.0043 0.2056
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0067 0.0063
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0026 0.0021 0.0017
Brugia malayi Protein kinase domain containing protein 0.0034 0.0034 0.0034
Schistosoma mansoni sorting nexin 0.0026 0.0021 0.0017
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.0026 0.0021 0.0287
Brugia malayi hypothetical protein 0.023 0.0335 0.0335
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0247 0.6291
Echinococcus multilocularis histone acetyltransferase MYST2 0.0063 0.0078 0.0074
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0008 0.0004
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0026 0.0021 0.0017
Echinococcus multilocularis transfer RNA-Ala 0.0026 0.0021 0.0017
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0022 0.0022
Echinococcus granulosus intersectin 2 0.0026 0.0021 0.0017
Entamoeba histolytica unconventional myosin IB 0.0026 0.0021 0.0374
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.001 0.0006
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0018 0.0009 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0193 0.0277 0.0273
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0155 0.022 0.0216
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.2418 0.3707 0.3704
Brugia malayi hypothetical protein 0.0016 0.0006 0.0006
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0027 0.0022 0.0018
Echinococcus multilocularis expressed conserved protein 0.0194 0.028 0.0276
Loa Loa (eye worm) hypothetical protein 0.0035 0.0034 0.0034
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0193 0.0277 0.0273
Brugia malayi Steroid receptor seven-up type 2 0.0035 0.0034 0.0034
Loa Loa (eye worm) p53BP2 0.0026 0.0021 0.0021
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.001 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0035 0.0034 0.0034
Echinococcus granulosus thyroid hormone receptor alpha 0.0016 0.0006 0.0002
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0147 0.0208 0.0204
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0072 0.0072
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.001 0.0006
Mycobacterium leprae conserved hypothetical protein 0.004 0.0043 0.1741
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0009 0.0009
Schistosoma mansoni suppressor of cytokine signaling 0.0027 0.0022 0.0018
Leishmania major mitochondrial DNA polymerase beta 0.0328 0.0486 0.0482
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0008 0.0113
Echinococcus granulosus fructose 16 bisphosphatase 1 0.6503 1 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Schistosoma mansoni GTPase activating protein 0.0027 0.0022 0.0018
Schistosoma mansoni dreadlocks/dock 0.0026 0.0021 0.0017
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0022 0.0399
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0026 0.0021 0.0017
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0018 0.0009 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0362 0.0538 0.0534
Entamoeba histolytica hypothetical protein 0.0026 0.0021 0.0374
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Schistosoma mansoni apoptosis stimulating of P53 0.0026 0.0021 0.0017
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.001 0.0494
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0006 0.0002
Plasmodium vivax stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative 0.0057 0.0069 0.3327
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0027 0.0022 0.0018
Schistosoma mansoni hypothetical protein 0.0085 0.0112 0.0108
Loa Loa (eye worm) fatty acid desaturase 0.0015 0.0004 0.0004
Brugia malayi SH2 domain containing protein 0.0027 0.0022 0.0022
Loa Loa (eye worm) MBCTL1 0.0063 0.0078 0.0078
Brugia malayi mbt repeat family protein 0.0055 0.0066 0.0066
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0009 0.0005
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0053 0.0062 0.0058
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0072 0.0068
Entamoeba histolytica hypothetical protein 0.0026 0.0021 0.0374
Toxoplasma gondii fructose-bisphospatase II 0.6503 1 1
Brugia malayi protein-tyrosine kinase 0.0026 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0018 0.0009 0.0005
Entamoeba histolytica hypothetical protein 0.0026 0.0021 0.0374
Onchocerca volvulus 0.0055 0.0066 0.2672
Schistosoma mansoni hypothetical protein 0.004 0.0042 0.0038
Echinococcus granulosus NCK adaptor protein 0.0053 0.0062 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0387 1
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0207 0.0299 1
Brugia malayi Peripheral plasma membrane protein CASK 0.0026 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.004 0.0043 0.0043
Echinococcus multilocularis tyrosine protein kinase shark 0.0034 0.0034 0.003
Echinococcus multilocularis tyrosine kinase 0.0034 0.0034 0.003
Brugia malayi thymidylate synthase 0.0105 0.0142 0.0142
Echinococcus multilocularis SH2 domain containing protein 7 0.0027 0.0022 0.0018
Entamoeba histolytica protein kinase, putative 0.0027 0.0022 0.041
Echinococcus granulosus GPCR family 2 0.0018 0.0009 0.0005
Schistosoma mansoni tensin 0.0027 0.0022 0.0018
Loa Loa (eye worm) protein-tyrosine kinase 0.0026 0.0021 0.0021
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0034 0.0034
Schistosoma mansoni nuclear receptor nhr-48 0.0016 0.0006 0.0002
Brugia malayi hypothetical protein 0.0018 0.0009 0.0009
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0035 0.0034 0.003
Onchocerca volvulus 0.0034 0.0034 0.1365
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0011 0.0197
Echinococcus multilocularis thyroid hormone receptor alpha 0.0035 0.0034 0.003
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0027 0.0022 0.0018
Onchocerca volvulus 0.0026 0.0021 0.0853
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0026 0.0021 0.0017
Mycobacterium tuberculosis Conserved hypothetical protein 0.0173 0.0247 0.6514
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.0152
Schistosoma mansoni tensin-related 0.0027 0.0022 0.0018
Loa Loa (eye worm) steroid hormone receptor 0.0035 0.0034 0.0034
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0043 0.1037
Echinococcus granulosus tensin 0.0027 0.0022 0.0018
Echinococcus granulosus epidermal growth factor receptor kinase 0.0026 0.0021 0.0017
Loa Loa (eye worm) acyl-CoA desaturase 0.0057 0.0069 0.0069
Loa Loa (eye worm) guanylate kinase 0.0026 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0018 0.0009 0.0005
Entamoeba histolytica hypothetical protein 0.0026 0.0021 0.0374
Echinococcus granulosus SAM and MBT domain containing protein 0.0055 0.0066 0.0062
Echinococcus multilocularis c src tyrosine kinase 0.0061 0.0074 0.007
Trypanosoma brucei sedoheptulose-1,7-bisphosphatase 0.2418 0.3707 0.3704
Onchocerca volvulus 0.0034 0.0034 0.1365
Echinococcus granulosus expressed conserved protein 0.0027 0.0022 0.0018
Schistosoma mansoni hypothetical protein 0.0085 0.0112 0.0108
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.007 0.007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.0152
Onchocerca volvulus 0.0027 0.0022 0.0894
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0027 0.0022 0.0018
Echinococcus granulosus endophilin A3 0.0026 0.0021 0.0017
Loa Loa (eye worm) hypothetical protein 0.004 0.0043 0.0043
Loa Loa (eye worm) fructose-1,6-bisphosphatase 0.6503 1 1
Loa Loa (eye worm) SH2 domain-containing protein 0.0027 0.0022 0.0022
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0061 0.0074 0.007
Onchocerca volvulus Bile acid receptor homolog 0.0035 0.0034 0.1372
Echinococcus multilocularis SH2 motif 0.0027 0.0022 0.0018
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0035 0.0034 0.003
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0027 0.0022 0.0894
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0008 0.0397
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0034 0.0034
Echinococcus granulosus N chimaerin 0.0027 0.0022 0.0018
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0011 0.0549
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0035 0.0034 0.0034
Onchocerca volvulus 0.0035 0.0034 0.1372
Brugia malayi tRNA modification GTPase TrmE family protein 0.0027 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0009
Schistosoma mansoni signal transduction protein lnk-related 0.0027 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.0335 0.0332
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0022 0.0476
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0009
Loa Loa (eye worm) FAT-3 protein 0.0015 0.0004 0.0004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0027 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0026 0.0021 0.0017
Onchocerca volvulus 0.004 0.0043 0.1728
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.001 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0387 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0035 0.0034 0.1372
Schistosoma mansoni tyrosine kinase 0.0061 0.0074 0.007
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 0.6503 1 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Echinococcus multilocularis thymidylate synthase 0.0105 0.0142 0.0138
Brugia malayi nuclear hormone receptor 0.0016 0.0006 0.0006
Toxoplasma gondii sedoheptulose-1,7-bisphosphatase 0.2418 0.3707 0.3707
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0362 0.0538 0.0534
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0026 0.0021 0.0017
Onchocerca volvulus 0.0027 0.0022 0.0894
Brugia malayi hypothetical protein 0.0027 0.0022 0.0022
Echinococcus granulosus tyrosine protein kinase Srms 0.0034 0.0034 0.003
Mycobacterium ulcerans lipase LipD 0.004 0.0043 0.1592
Brugia malayi isocitrate dehydrogenase 0.0018 0.0008 0.0008
Echinococcus granulosus hypothetical protein 0.0027 0.0022 0.0018
Brugia malayi nuclear receptor RXR 0.0018 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0207 0.0299 0.0299
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0053 0.0062 0.0062
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Echinococcus granulosus sterol regulatory element binding protein 0.0089 0.0117 0.0113
Echinococcus granulosus polycomb protein SCMH1 0.0055 0.0066 0.0062
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0027 0.0022 0.0018
Echinococcus granulosus thymidylate synthase 0.0105 0.0142 0.0138
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0072 0.0068
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0387 1
Chlamydia trachomatis dihydrofolate reductase 0.0043 0.0046 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0193 0.0277 0.0273
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0043 0.0039
Brugia malayi SH2 domain containing protein 0.0027 0.0022 0.0022
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0008 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0008 0.0004
Brugia malayi SRC-1 0.0061 0.0074 0.0074
Schistosoma mansoni tensin 0.0027 0.0022 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0035 0.0034 0.0034
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0193 0.0277 0.0277
Brugia malayi Niemann-Pick C1 protein precursor 0.0207 0.0299 0.0299
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0034 0.0034
Schistosoma mansoni thyroid hormone receptor 0.0035 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.023 0.0335 0.0335
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0147 0.0208 1
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0043 0.0861
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0035 0.0034 0.0034
Brugia malayi nuclear receptor NHR-88 0.0016 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0463 0.0694 0.069
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.001 0.0006
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0035 0.0034 0.003
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0006 0.0002
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0043 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0387 1
Echinococcus granulosus FTZ F1 alpha 0.0035 0.0034 0.003
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0026 0.0021 0.0017
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0026 0.0021 0.0017
Echinococcus granulosus nuclear receptor nhr 48 0.0016 0.0006 0.0002
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0026 0.0021 0.0021
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0008 0.0008
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0061 0.0074 0.007
Brugia malayi SH2 domain containing protein 0.0027 0.0022 0.0022
Schistosoma mansoni RAR-like nuclear receptor 0.0035 0.0034 0.003
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0063 0.0078 0.0078
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0193 0.0277 0.0273
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0034 0.0034 0.003
Onchocerca volvulus 0.0034 0.0034 0.1365
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Mycobacterium ulcerans hypothetical protein 0.004 0.0043 0.1592
Brugia malayi Tyrosine-protein kinase abl-1 0.0061 0.0074 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0034 0.0034
Brugia malayi conserved hypotetical protein 0.0016 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0043 0.1037
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0328 0.0486 0.0482
Echinococcus multilocularis ecdysone induced protein 78C 0.0035 0.0034 0.003
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0061 0.0074 0.007
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0063 0.0078 0.0074
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0034 0.003
Echinococcus granulosus nostrin 0.0026 0.0021 0.0017
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0006 0.0006
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.001 0.001
Toxoplasma gondii LsmAD domain-containing protein 0.0056 0.0067 0.0067
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0061 0.0074 0.007
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0035 0.0034 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0021 0.0287
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0072 0.2792
Schistosoma mansoni suppressor of cytokine signaling 0.0027 0.0022 0.0018
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0034 0.0034
Schistosoma mansoni thyroid hormone receptor 0.0035 0.0034 0.003
Brugia malayi Variant SH3 domain containing protein 0.0053 0.0062 0.0062
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0027 0.0022 0.0018
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0034 0.003
Schistosoma mansoni hypothetical protein 0.0025 0.0019 0.0015
Schistosoma mansoni ap endonuclease 0.0019 0.001 0.0006
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0009 0.0009
Trichomonas vaginalis esterase, putative 0.004 0.0043 0.0861
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0066 0.0062
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0026 0.0021 0.0017
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0155 0.022 0.0216
Loa Loa (eye worm) hypothetical protein 0.0056 0.0067 0.0067
Echinococcus multilocularis tyrosine protein kinase Blk 0.0034 0.0034 0.003
Onchocerca volvulus 0.0034 0.0034 0.1365
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0034 0.003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.0152
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0061 0.0074 0.007
Onchocerca volvulus 0.0015 0.0004 0.0164
Echinococcus multilocularis nuclear receptor nhr 48 0.0016 0.0006 0.0002
Brugia malayi hypothetical protein 0.005 0.0057 0.0057
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0021 0.0021
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0067 0.3218
Echinococcus granulosus tyrosine protein kinase ABL1 0.0034 0.0034 0.003
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0055 0.0066 0.0062
Schistosoma mansoni hypothetical protein 0.0026 0.0021 0.0017
Brugia malayi SH2 domain containing protein 0.0027 0.0022 0.0022
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0027 0.0022 0.0018
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0008 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0021 0.0287
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0087 0.0083
Mycobacterium tuberculosis Conserved protein 0.004 0.0043 0.1037
Schistosoma mansoni coup transcription factor 0.0035 0.0034 0.003
Echinococcus multilocularis FTZ F1 alpha 0.0035 0.0034 0.003
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0061 0.0074 0.007
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0027 0.0022 0.0018
Echinococcus granulosus expressed protein 0.0026 0.0021 0.0017
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.0026 0.0021 0.0017
Schistosoma mansoni hypothetical protein 0.0047 0.0053 0.0049
Brugia malayi orphan nuclear receptor NR2E1 0.0016 0.0006 0.0006
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0027 0.0022 0.0018
Schistosoma mansoni hypothetical protein 0.0027 0.0022 0.0018
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0043 0.1037
Loa Loa (eye worm) hypothetical protein 0.004 0.0043 0.0043
Entamoeba histolytica hypothetical protein 0.0026 0.0021 0.0374
Entamoeba histolytica hypothetical protein, conserved 0.0026 0.0021 0.0374
Echinococcus granulosus src region 0.0026 0.0021 0.0017
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0008 0.0397
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0026 0.0021 0.0017
Leishmania major 0.6503 1 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Onchocerca volvulus 0.004 0.0043 0.1728
Echinococcus granulosus tyrosine protein kinase shark 0.0034 0.0034 0.003
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0067 0.3218
Schistosoma mansoni cpg binding protein 0.0032 0.0031 0.0027
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0022 0.0476
Echinococcus multilocularis Niemann Pick C1 protein 0.0207 0.0299 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0057 0.1252
Schistosoma mansoni cpg binding protein 0.0034 0.0034 0.003
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0042 0.0042
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0072 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0035 0.0034 0.0034
Echinococcus granulosus signal transduction protein lnk realted 0.0027 0.0022 0.0018
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0043 0.0861
Entamoeba histolytica hypothetical protein 0.0026 0.0021 0.0374
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0022 0.073
Onchocerca volvulus 0.0027 0.0022 0.0894
Loa Loa (eye worm) TK/ABL protein kinase 0.0034 0.0034 0.0034
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0043 0.1592
Brugia malayi SH2 domain containing protein 0.0027 0.0022 0.0022
Brugia malayi hypothetical protein 0.0016 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0009
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0006 0.0002
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0052 0.0048
Brugia malayi hypothetical protein 0.0056 0.0067 0.0067
Loa Loa (eye worm) nuclear hormone receptor 0.0016 0.0006 0.0006
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0257 0.0377 1
Brugia malayi Tensin 0.0027 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0018 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0055 0.0066 0.0066
Trypanosoma cruzi fatty acid desaturase, putative 0.0057 0.0069 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0034 0.0034
Brugia malayi CHE-14 protein 0.0089 0.0117 0.0117
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0016 0.0006 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0022 0.0022
Brugia malayi SH3 domain containing protein 0.0026 0.0021 0.0021
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.0067 0.0063
Leishmania major hypothetical protein, conserved 0.0026 0.0021 0.0017
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0247 0.6291
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0022 0.0018
Onchocerca volvulus 0.0034 0.0034 0.1365
Echinococcus multilocularis SHC transforming protein 3 0.0027 0.0022 0.0018
Echinococcus multilocularis intersectin 2 0.0026 0.0021 0.0017
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0026 0.0021 0.0017
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0035 0.0034 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0034 0.0034
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0022 0.0018
Schistosoma mansoni hypothetical protein 0.004 0.0043 0.0039
Echinococcus granulosus suppressor of cytokine signaling 6 0.0027 0.0022 0.0018
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0034 0.0034
Schistosoma mansoni cell polarity protein 0.0026 0.0021 0.0017
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0016 0.0006 0.0002
Schistosoma mansoni zinc finger protein 0.0016 0.0006 0.0002
Brugia malayi ecdysteroid receptor 0.0035 0.0034 0.0034
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0021 0.0021
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0009 0.0009
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0027 0.0022 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0387 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0018 0.0009 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0006 0.0002
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0027 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0043 0.1037
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0016 0.0006 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0022 0.073
Brugia malayi nuclear receptor NHR-67 0.0016 0.0006 0.0006
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.005 0.0057 0.0053
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0067 0.0063
Echinococcus granulosus SH2 motif 0.0027 0.0022 0.0018
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0008 0.0004
Schistosoma mansoni retinoic acid receptor RXR 0.0035 0.0034 0.003

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 15.9 umol Cytotoxicity against human HL60 cells after 48 hrs by MTT assay ChEMBL. 20462230
IC50 (functional) = 22.1 umol Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay ChEMBL. 20462230
IC50 (functional) = 29.3 umol Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay ChEMBL. 20462230
IC50 (functional) = 32.2 umol Cytotoxicity against human SW480 cells after 48 hrs by MTT assay ChEMBL. 20462230
IC50 (functional) > 40 umol Cytotoxicity against human A549 cells after 48 hrs by MTT assay ChEMBL. 20462230

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 20462230

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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