Detailed information for compound 1142381

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 408.921 | Formula: C24H25ClN2O2
  • H donors: 0 H acceptors: 1 LogP: 5.26 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)c1noc(c1)[C@@H]1C2CCC(N2C)C[C@@H]1c1ccc(cc1)Cl
  • InChi: 1S/C24H25ClN2O2/c1-27-18-9-12-22(27)24(20(13-18)15-3-7-17(25)8-4-15)23-14-21(26-29-23)16-5-10-19(28-2)11-6-16/h3-8,10-11,14,18,20,22,24H,9,12-13H2,1-2H3/t18?,20-,22?,24+/m1/s1
  • InChiKey: MZBDCJWEXVZTQQ-XFLMMPOFSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.012 0.0632 0.0981
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0266 0.0413
Brugia malayi TAR-binding protein 0.0266 0.1508 0.2343
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0099 0.0503 0.0782
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0056 0.0241 0.0374
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0127 0.0198
Loa Loa (eye worm) hypothetical protein 0.0072 0.0341 0.0531
Brugia malayi RNA binding protein 0.0266 0.1508 0.2343
Echinococcus multilocularis integrin alpha ps 0.0053 0.0225 0.0225
Schistosoma mansoni hypothetical protein 0.1068 0.6336 0.9844
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.002 0.0028 0.0028
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0028 0.0028
Onchocerca volvulus 0.0183 0.101 0.295
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0028 0.0044
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0471 0.2743 0.2743
Onchocerca volvulus 0.0183 0.101 0.295
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0773 0.1201
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0099 0.0503 0.0782
Echinococcus multilocularis integrin alpha ps 0.011 0.0571 0.0571
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0028 0.0028
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Loa Loa (eye worm) carboxylesterase 0.1085 0.6436 1
Echinococcus multilocularis nAChR subunit 0.0065 0.0297 0.0297
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0055 0.0086
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Onchocerca volvulus 0.012 0.0632 0.1845
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.0105 0.0163
Echinococcus multilocularis muscleblind protein 0.0309 0.1766 0.1766
Brugia malayi nuclear hormone receptor 0.0033 0.0105 0.0163
Echinococcus multilocularis expressed protein 0.002 0.0028 0.0028
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0291 0.1661 0.258
Loa Loa (eye worm) hypothetical protein 0.0076 0.0364 0.0566
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0105 0.0163
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0152 0.082 0.1274
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.012 0.0632 0.0981
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.0105 0.0163
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0115 0.0601 0.0934
Schistosoma mansoni neuroligin 3 (S09 family) 0.0183 0.101 0.1569
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0471 0.2743 0.4262
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.012 0.0632 0.0981
Echinococcus granulosus integrin alpha ps 0.0053 0.0225 0.035
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0364 0.1087
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.002 0.003
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0584 0.3422 0.5317
Schistosoma mansoni ap endonuclease 0.0019 0.002 0.003
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0028 0.0044
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0033 0.0105 0.0105
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0056 0.0241 0.0374
Schistosoma mansoni hypothetical protein 0.0115 0.0601 0.0934
Schistosoma mansoni cpg binding protein 0.0029 0.0082 0.0127
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.0364 0.1226
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.0364 0.1226
Loa Loa (eye worm) hypothetical protein 0.0183 0.101 0.1569
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0052 0.0676
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.002 0.0028 0.0044
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0266 0.0413
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0099 0.0503 0.0782
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0056 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Echinococcus multilocularis glycine receptor subunit alpha 1 0.012 0.0632 0.0632
Onchocerca volvulus 0.012 0.0632 0.1845
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.002 0.0028 0.0044
Loa Loa (eye worm) TAR-binding protein 0.0266 0.1508 0.2343
Plasmodium falciparum transporter, putative 0.0099 0.0503 1
Echinococcus multilocularis GPCR, family 2 0.0115 0.0601 0.0601
Onchocerca volvulus Putative nachr subunit 0.0291 0.1661 0.4852
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.002 0.003
Schistosoma mansoni tar DNA-binding protein 0.0266 0.1508 0.2343
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0115 0.0601 0.0601
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0306 0.0475
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0486 0.283 1
Trichomonas vaginalis glucosylceramidase, putative 0.0358 0.206 0.6439
Loa Loa (eye worm) hypothetical protein 0.0157 0.0851 0.1321
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0291 0.1661 0.1661
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.012 0.0632 0.0981
Echinococcus granulosus expressed protein 0.002 0.0028 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.0105 0.0163
Plasmodium vivax hypothetical protein, conserved 0.0099 0.0503 1
Schistosoma mansoni tar DNA-binding protein 0.0266 0.1508 0.2343
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.0057 0.0252 0.0392
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.012 0.0632 0.0981
Toxoplasma gondii hypothetical protein 0.0099 0.0503 1
Brugia malayi beta-lactamase family protein 0.0076 0.0364 0.0566
Trichomonas vaginalis glucosylceramidase, putative 0.0358 0.206 0.6439
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0104 0.286
Loa Loa (eye worm) hypothetical protein 0.0065 0.0297 0.0462
Loa Loa (eye worm) hypothetical protein 0.0033 0.0105 0.0163
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0309 0.1766 0.2744
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0813 0.0813
Brugia malayi hypothetical protein 0.0056 0.0241 0.0374
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.002 0.0028 0.0044
Echinococcus granulosus tar DNA binding protein 0.0266 0.1508 0.2343
Brugia malayi hypothetical protein 0.002 0.0028 0.0044
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0056 0.0241 0.0241
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0011 0.0017
Schistosoma mansoni hypothetical protein 0.1068 0.6336 0.9844
Loa Loa (eye worm) ACC-1 protein 0.012 0.0632 0.0981
Brugia malayi Carboxylesterase family protein 0.1085 0.6436 1
Loa Loa (eye worm) hypothetical protein 0.0309 0.1766 0.2744
Schistosoma mansoni nAChR subunit 0.012 0.0632 0.0981
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0471 0.2743 0.4262
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0813 0.1263
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.0105 0.0163
Echinococcus granulosus serotonin transporter 0.0584 0.3422 0.5317
Entamoeba histolytica hypothetical protein 0.0037 0.0128 0.39
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0813 0.1263
Brugia malayi Muscleblind-like protein 0.0309 0.1766 0.2744
Echinococcus multilocularis carboxylesterase 5A 0.1085 0.6436 0.6436
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.002 0.0522
Brugia malayi hypothetical protein 0.0056 0.0241 0.0374
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0052 0.1421
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0279 0.0433
Schistosoma mansoni tar DNA-binding protein 0.0266 0.1508 0.2343
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0128 0.0198
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Entamoeba histolytica hypothetical protein 0.0037 0.0128 0.39
Entamoeba histolytica hypothetical protein 0.0037 0.0128 0.39
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.0364 0.0566
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.012 0.0632 0.0981
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1085 0.6436 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0099 0.0503 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.012 0.0632 0.0981
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0033 0.0105 0.0105
Onchocerca volvulus 0.0065 0.0297 0.0868
Loa Loa (eye worm) carboxylesterase 0.0183 0.101 0.1569
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0017
Trichomonas vaginalis glucosylceramidase, putative 0.0358 0.206 0.6439
Schistosoma mansoni integrin alpha-ps 0.011 0.0571 0.0887
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0291 0.1661 0.258
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0291 0.1661 0.1661
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.0105 0.0163
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.012 0.0632 0.0981
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Trichomonas vaginalis ran, putative 0.0024 0.0052 0.0103
Brugia malayi Carboxylesterase family protein 0.0183 0.101 0.1569
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.002 0.0028 0.0044
Loa Loa (eye worm) beta-lactamase 0.0076 0.0364 0.0566
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0065 0.0297 0.0462
Echinococcus granulosus snurportin 1 0.0351 0.2021 0.314
Echinococcus granulosus integrin alpha 3 0.0189 0.1043 0.162
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0067 0.015
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0056 0.0241 0.0374
Schistosoma mansoni gliotactin 0.0183 0.101 0.1569
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0028 0.0044
Echinococcus multilocularis thyroid hormone receptor alpha 0.0033 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0584 0.3422 0.5317
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0183 0.0517
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.012 0.0632 0.0981
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.012 0.0632 0.0981
Schistosoma mansoni hypothetical protein 0.0115 0.0601 0.0934
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.012 0.0632 0.0981
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0147 0.2631
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0128 0.0128
Echinococcus multilocularis serotonin transporter 0.0584 0.3422 0.3422
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0065 0.0297 0.0462
Loa Loa (eye worm) hypothetical protein 0.0115 0.0601 0.0934
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0364 0.5
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.012 0.0632 0.0981
Loa Loa (eye worm) hypothetical protein 0.0033 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.1085 0.6436 1
Loa Loa (eye worm) hypothetical protein 0.0183 0.101 0.1569
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.012 0.0632 0.0981
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0266 0.2491
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.0105 0.0163
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0099 0.0503 0.0782
Echinococcus multilocularis glycine receptor subunit alpha 1 0.012 0.0632 0.0632
Loa Loa (eye worm) hypothetical protein 0.0099 0.0503 0.0782
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Schistosoma mansoni zinc finger protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0099 0.0503 0.0782
Loa Loa (eye worm) hypothetical protein 0.0183 0.101 0.1569
Echinococcus granulosus sodium and chloride dependent glycine 0.0099 0.0503 0.0782
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Brugia malayi G-protein alpha subunit 0.002 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Mycobacterium tuberculosis Conserved protein 0.0076 0.0364 0.1226
Echinococcus multilocularis para nitrobenzyl esterase 0.0183 0.101 0.101
Entamoeba histolytica G protein alpha subunit, putative 0.002 0.0028 0.0316
Loa Loa (eye worm) hypothetical protein 0.0193 0.107 0.1663
Loa Loa (eye worm) hypothetical protein 0.0584 0.3422 0.5317
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0183 0.0285
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0099 0.0503 0.0782
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0028 0.0028
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0364 0.7122
Echinococcus multilocularis geminin 0.1068 0.6336 0.6336
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.0364 0.3479
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0044
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0291 0.1661 0.258
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0471 0.2743 0.4262
Onchocerca volvulus Glucosylceramidase homolog 0.0358 0.206 0.6018
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0306 0.0306
Echinococcus granulosus ecdysone induced protein 78C 0.0033 0.0105 0.0163
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.002 0.0028 0.0044
Echinococcus multilocularis acetylcholinesterase 0.1085 0.6436 0.6436
Echinococcus multilocularis tar DNA binding protein 0.0266 0.1508 0.1508
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.012 0.0632 0.0981
Loa Loa (eye worm) hypothetical protein 0.0039 0.0142 0.0221
Loa Loa (eye worm) hypothetical protein 0.0053 0.0225 0.035
Toxoplasma gondii ABC1 family protein 0.0076 0.0364 0.7122
Plasmodium falciparum importin beta, putative 0.0033 0.0104 0.1757
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0105 0.0163
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0052 0.0676
Loa Loa (eye worm) hypothetical protein 0.0065 0.0297 0.0462
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Onchocerca volvulus 0.0056 0.0241 0.0704
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0351 0.2021 0.314
Brugia malayi hypothetical protein 0.0099 0.0503 0.0782
Schistosoma mansoni integrin alpha-ps 0.0057 0.0252 0.0392
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0584 0.3422 0.5317
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.002 0.5
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.002 0.003
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0183 0.101 0.1569
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0105 0.0163
Schistosoma mansoni nAChR subunit 0.012 0.0632 0.0981
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0266 0.0413
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.012 0.0632 0.0981
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.0105 0.0163
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0028 0.0028
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0266 0.7307
Echinococcus granulosus zinc finger protein 0.0025 0.0059 0.0091
Plasmodium falciparum amino acid transporter, putative 0.0099 0.0503 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.0076 0.0364 0.0566
Loa Loa (eye worm) hypothetical protein 0.0033 0.0104 0.0162
Loa Loa (eye worm) hypothetical protein 0.0065 0.0297 0.0462
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0044
Schistosoma mansoni hypothetical protein 0.0016 0.0001 0.0001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0056 0.0241 0.0374
Toxoplasma gondii hypothetical protein 0.0099 0.0503 1
Schistosoma mansoni nAChR subunit 0.012 0.0632 0.0981
Loa Loa (eye worm) hypothetical protein 0.0099 0.0503 0.0782
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0028 0.0044
Loa Loa (eye worm) ACC-1 protein 0.012 0.0632 0.0981
Schistosoma mansoni neurotransmitter gated ion channel 0.0056 0.0241 0.0374
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0266 0.0878
Loa Loa (eye worm) hypothetical protein 0.0033 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.1085 0.6436 1
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.0105 0.0163
Trichomonas vaginalis glucosylceramidase, putative 0.0358 0.206 0.6439
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0364 0.0566
Loa Loa (eye worm) hypothetical protein 0.0065 0.0297 0.0462
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.002 0.0028 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0377 0.2175 0.6804
Schistosoma mansoni nAChR subunit 0.012 0.0632 0.0981
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.0183 0.101 0.1569
Echinococcus granulosus sodium and chloride dependent glycine 0.0099 0.0503 0.0782
Echinococcus multilocularis ecdysone induced protein 78C 0.0033 0.0105 0.0105
Echinococcus multilocularis muscleblind protein 1 0.0309 0.1766 0.1766
Brugia malayi hypothetical protein 0.0056 0.0241 0.0374
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0183 0.101 0.1569
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0017
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0099 0.0503 0.0782
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0056 0.0241 0.0374
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0291 0.1661 0.1661
Echinococcus granulosus neuroligin 0.0183 0.101 0.1569
Schistosoma mansoni ran 0.0024 0.0052 0.0081
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.012 0.0632 0.0981
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0033 0.0105 0.0163
Brugia malayi latrophilin 2 splice variant baaae 0.0249 0.1408 0.2187
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0067 0.1829
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.012 0.0632 0.0981
Echinococcus granulosus FTZ F1 alpha 0.0033 0.0105 0.0163
Mycobacterium tuberculosis Conserved protein 0.0076 0.0364 0.1226
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0105 0.0105
Echinococcus granulosus GPCR family 2 0.0115 0.0601 0.0934
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0017
Brugia malayi Latrophilin receptor protein 2 0.0115 0.0601 0.0934
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0105 0.0163
Trichomonas vaginalis esterase, putative 0.0076 0.0364 0.1087
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0015 0.0024
Plasmodium vivax amine transporter, putative 0.0099 0.0503 1
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0291 0.1661 0.258
Brugia malayi Cation transporter family protein 0.012 0.0632 0.0981
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0266 0.2491
Loa Loa (eye worm) G protein alpha subunit 3 0.002 0.0028 0.0044
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.002 0.0028 0.0028
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.012 0.0632 0.0981
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0364 0.1087
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0028 0.0044
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0105 0.0163
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.002 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0249 0.1408 0.2187
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0052 0.0081
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Schistosoma mansoni survival motor neuron protein 0.0152 0.082 0.1274
Echinococcus multilocularis glycine receptor subunit beta 0.012 0.0632 0.0632
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0033 0.0052
Echinococcus multilocularis snurportin 1 0.0351 0.2021 0.2021
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0033 0.0105 0.0163
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0266 0.2491
Trichomonas vaginalis glucosylceramidase, putative 0.0545 0.3188 1
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0028 0.0044
Echinococcus granulosus geminin 0.1068 0.6336 0.9844
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Brugia malayi hypothetical protein 0.0056 0.0241 0.0374
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0028 0.0044
Brugia malayi Carboxylesterase family protein 0.0183 0.101 0.1569
Loa Loa (eye worm) hypothetical protein 0.0744 0.4386 0.6815
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0105 0.0105
Echinococcus granulosus acetylcholinesterase 0.1085 0.6436 1
Echinococcus granulosus nAChR subunit 0.012 0.0632 0.0981
Mycobacterium tuberculosis Conserved protein 0.0076 0.0364 0.1226
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Brugia malayi Cation transporter family protein 0.012 0.0632 0.0981
Loa Loa (eye worm) hypothetical protein 0.0065 0.0297 0.0462
Loa Loa (eye worm) hypothetical protein 0.0053 0.0225 0.035
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.012 0.0632 0.0981
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.0105 0.0163
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.002 0.0028 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0105 0.0163
Echinococcus multilocularis tumor protein p63 0.0358 0.2061 0.2061
Plasmodium vivax importin-beta 2, putative 0.0033 0.0104 0.1757
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0183 0.101 0.1569
Loa Loa (eye worm) hypothetical protein 0.0183 0.101 0.1569
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0099 0.0503 0.0782
Onchocerca volvulus 0.0076 0.0364 0.1064
Onchocerca volvulus 0.0052 0.0222 0.0648
Brugia malayi hypothetical protein 0.0017 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0076 0.0364 0.0566
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.0105 0.0163
Schistosoma mansoni hypothetical protein 0.0351 0.2021 0.314
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0291 0.1661 0.258
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.0105 0.0306
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0099 0.0503 0.0782
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0364 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.0105 0.0163
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0364 0.0566
Trichomonas vaginalis glucosylceramidase, putative 0.0545 0.3188 1
Schistosoma mansoni coup transcription factor 0.0033 0.0105 0.0163
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0011 0.0011
Echinococcus granulosus BC026374 protein S09 family 0.0183 0.101 0.1569
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0364 0.1087
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0065 0.0297 0.0462
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.0503 0.0782
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0105 0.0163
Brugia malayi Bromodomain containing protein 0.0043 0.0164 0.0255
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0052 0.0676
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.012 0.0632 0.0632
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0067 0.015
Onchocerca volvulus 0.012 0.0632 0.1845
Trichomonas vaginalis glucosylceramidase, putative 0.0545 0.3188 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0033 0.0105 0.0163
Schistosoma mansoni neurotransmitter gated ion channel 0.0065 0.0297 0.0462
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.012 0.0632 0.0981
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.0105 0.0163
Brugia malayi Importin beta-1 subunit 0.0033 0.0104 0.0162
Brugia malayi Carboxylesterase family protein 0.0183 0.101 0.1569
Echinococcus granulosus glycine receptor subunit alpha 1 0.012 0.0632 0.0981
Schistosoma mansoni bromodomain containing protein 0.007 0.0328 0.0509
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0052 0.0081
Schistosoma mansoni trimeric G-protein alpha o subunit 0.002 0.0028 0.0044
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0028 0.0044
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0037 0.0057
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0364 0.1087
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0365 0.2102 0.3267
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0128 0.0198
Loa Loa (eye worm) hypothetical protein 0.0033 0.0105 0.0163
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0183 0.3384
Brugia malayi ecdysteroid receptor 0.0033 0.0105 0.0163
Brugia malayi hypothetical protein 0.0744 0.4386 0.6815
Brugia malayi hypothetical protein 0.0037 0.0128 0.0198
Echinococcus granulosus nAChR subunit 0.0065 0.0297 0.0462
Brugia malayi Steroid receptor seven-up type 2 0.0033 0.0105 0.0163
Echinococcus granulosus tumor protein p63 0.0358 0.2061 0.3202
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0015 0.0024
Echinococcus granulosus carboxylesterase 5A 0.1085 0.6436 1
Brugia malayi hypothetical protein 0.0017 0.0011 0.0017
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.012 0.0632 0.0981
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0275 0.5289
Loa Loa (eye worm) hypothetical protein 0.0033 0.0105 0.0163
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0471 0.2743 0.2743
Onchocerca volvulus 0.0076 0.0364 0.1064
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0055 0.0055
Mycobacterium ulcerans lipase LipD 0.0076 0.0364 0.3479
Brugia malayi PHD-finger family protein 0.0031 0.0092 0.0142
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0011 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0105 0.0163
Echinococcus multilocularis FTZ F1 alpha 0.0033 0.0105 0.0105
Loa Loa (eye worm) LGC-31 protein 0.012 0.0632 0.0981
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0099 0.0503 0.0782
Leishmania major hypothetical protein, conserved 0.0076 0.0364 1
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0028 0.0044
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0028 0.0028
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.002 0.0028 0.0028
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0033 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0065 0.0297 0.0462
Treponema pallidum sodium- and chloride- dependent transporter 0.0584 0.3422 1
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0099 0.0503 0.0503
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0011 0.0017
Schistosoma mansoni hypothetical protein 0.0053 0.0225 0.035
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0015 0.0015
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0471 0.2743 0.4262
Schistosoma mansoni hypothetical protein 0.0021 0.0033 0.0052
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0011 0.0011
Echinococcus granulosus acetylcholinesterase 0.1085 0.6436 1
Brugia malayi nuclear receptor NHR-88 0.0033 0.0105 0.0163
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0065 0.0297 0.0462
Loa Loa (eye worm) hypothetical protein 0.0033 0.0105 0.0163
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0055 0.0086
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0056 0.0241 0.0374
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.0364 0.0364
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.0105 0.0163
Schistosoma mansoni hypothetical protein 0.0249 0.1408 0.2187
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0624 0.097
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0127 0.0127
Trichomonas vaginalis glucosylceramidase, putative 0.0545 0.3188 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0183 0.101 0.3523
Echinococcus multilocularis glycine receptor subunit beta 0.012 0.0632 0.0632
Mycobacterium ulcerans hypothetical protein 0.0076 0.0364 0.3479
Trichomonas vaginalis glucosylceramidase, putative 0.0545 0.3188 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0065 0.0297 0.0462
Loa Loa (eye worm) hypothetical protein 0.0136 0.0724 0.1125
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0278
Onchocerca volvulus 0.002 0.0028 0.0083
Loa Loa (eye worm) latrophilin receptor protein 2 0.0115 0.0601 0.0934
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0183 0.3384
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0056 0.0241 0.0374
Brugia malayi Cation transporter family protein 0.012 0.0632 0.0981
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.012 0.0632 0.0981
Onchocerca volvulus 0.0183 0.101 0.295
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0044
Schistosoma mansoni importin beta-1 0.0033 0.0104 0.0162
Echinococcus granulosus para nitrobenzyl esterase 0.0183 0.101 0.1569
Schistosoma mansoni hypothetical protein 0.0115 0.0601 0.0934
Schistosoma mansoni BC026374 protein (S09 family) 0.0183 0.101 0.1569
Brugia malayi RNA recognition motif domain containing protein 0.0266 0.1508 0.2343
Brugia malayi RNA, U transporter 1 0.0094 0.047 0.073
Schistosoma mansoni neurotransmitter gated ion channel 0.0056 0.0241 0.0374
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0052 0.2568
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0099 0.0503 1
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0067 0.015
Onchocerca volvulus 0.0099 0.0503 0.147
Loa Loa (eye worm) GABA receptor subunit 0.0065 0.0297 0.0462
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0099 0.0503 0.5
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.012 0.0632 0.0981
Trichomonas vaginalis spcc417.12 protein, putative 0.0183 0.101 0.3125
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.012 0.0632 0.0632
Schistosoma mansoni nAChR subunit 0.012 0.0632 0.0981
Loa Loa (eye worm) acetylcholine receptor protein 0.0056 0.0241 0.0374
Entamoeba histolytica hypothetical protein 0.0065 0.0297 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.012 0.0632 0.0981
Loa Loa (eye worm) serotonin transporter b 0.0584 0.3422 0.5317
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.002 0.0028 0.0028
Schistosoma mansoni zinc finger protein 0.0025 0.0059 0.0091
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0024
Schistosoma mansoni acetylcholine receptor subunit beta 0.0056 0.0241 0.0374
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0056 0.0241 0.0374
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.012 0.0632 0.0981
Trichomonas vaginalis glucosylceramidase, putative 0.0358 0.206 0.6439
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.0364 0.1226
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0183 0.101 0.101
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.012 0.0632 0.0981
Onchocerca volvulus 0.012 0.0632 0.1845
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.012 0.0632 0.0981
Echinococcus multilocularis sodium and chloride dependent glycine 0.0099 0.0503 0.0503
Mycobacterium leprae Probable lipase LipE 0.0076 0.0364 0.5
Schistosoma mansoni sodium/chloride dependent transporter 0.0584 0.3422 0.5317
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0099 0.0503 0.0782
Echinococcus multilocularis neuroligin 0.0183 0.101 0.101
Loa Loa (eye worm) hypothetical protein 0.0033 0.0105 0.0163
Schistosoma mansoni acetylcholinesterase 0.0183 0.101 0.1569
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0028 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0545 0.3188 1
Loa Loa (eye worm) solute carrier family 6 member 4 0.0584 0.3422 0.5317
Loa Loa (eye worm) hypothetical protein 0.0183 0.101 0.1569
Echinococcus multilocularis integrin alpha 3 0.0189 0.1043 0.1043
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.012 0.0632 0.0981
Loa Loa (eye worm) hypothetical protein 0.0291 0.1661 0.258
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.0364 0.1226
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.0503 0.0782
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.0364 0.3479
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.0105 0.0306
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0011 0.0018
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.0104 0.1757
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.0503 0.0782
Trichomonas vaginalis glucosylceramidase, putative 0.0358 0.206 0.6439
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0028 0.0044
Schistosoma mansoni nAChR subunit 0.0056 0.0241 0.0374
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0115 0.0601 0.0934
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0056 0.0241 0.0374
Echinococcus multilocularis cpg binding protein 0.0033 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Schistosoma mansoni sodium-dependent amino acid transporter 0.0099 0.0503 0.0782
Onchocerca volvulus 0.0099 0.0503 0.147
Schistosoma mansoni cpg binding protein 0.0033 0.0104 0.0161
Schistosoma mansoni acetylcholine receptor-related 0.0056 0.0241 0.0374
Onchocerca volvulus 0.012 0.0632 0.1845
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0033 0.0105 0.0163
Brugia malayi MH2 domain containing protein 0.0119 0.0624 0.097
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.0364 0.0566
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0015 0.0024
Echinococcus multilocularis survival motor neuron protein 1 0.0744 0.4386 0.4386
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.002 0.0028 0.0044
Brugia malayi Integrin alpha pat-2 precursor 0.0246 0.1389 0.2158
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0053 0.0225 0.035
Loa Loa (eye worm) carboxylesterase 0.0183 0.101 0.1569
Schistosoma mansoni hypothetical protein 0.0037 0.0128 0.0198
Brugia malayi hypothetical protein 0.0056 0.0241 0.0374
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.012 0.0632 0.0632
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0099 0.0503 0.0782
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0105 0.0163
Brugia malayi nuclear receptor RXR 0.0017 0.0011 0.0017
Onchocerca volvulus 0.0033 0.0105 0.0306
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0183 0.101 0.3125
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0033 0.0105 0.0163
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0056 0.0241 0.0374
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0266 0.0266
Echinococcus multilocularis zinc finger protein 0.0025 0.0059 0.0059
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0065 0.0297 0.0462
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0183 0.3384
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.002 0.0028 0.0044
Onchocerca volvulus 0.002 0.0028 0.0083
Echinococcus granulosus survival motor neuron protein 1 0.0744 0.4386 0.6815
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.012 0.0632 0.0981
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0099 0.0503 0.0503
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0266 0.5098
Schistosoma mansoni nAChR subunit 0.012 0.0632 0.0981
Schistosoma mansoni ap endonuclease 0.0019 0.002 0.003
Echinococcus granulosus cpg binding protein 0.0033 0.0104 0.0161
Brugia malayi Carboxylesterase family protein 0.0183 0.101 0.1569
Entamoeba histolytica hypothetical protein 0.0037 0.0128 0.39
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Loa Loa (eye worm) hypothetical protein 0.0365 0.2102 0.3267
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.0049 0.0201 0.0312
Onchocerca volvulus 0.0076 0.0364 0.1064
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0222 0.0345
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.002 0.0522
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0545 0.3188 0.4953
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.002 0.0028 0.0044
Brugia malayi beta-lactamase 0.0076 0.0364 0.0566
Leishmania major importin beta-1 subunit, putative 0.0027 0.0067 0.1829
Onchocerca volvulus 0.0099 0.0503 0.147
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0147 0.4586
Schistosoma mansoni nAChR subunit 0.0056 0.0241 0.0374
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0105 0.0163
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0052 0.0081
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0099 0.0503 0.0782
Loa Loa (eye worm) integrin alpha pat-2 0.0246 0.1389 0.2158
Brugia malayi Carboxylesterase family protein 0.1085 0.6436 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0183 0.101 0.3523
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.002 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0099 0.0503 0.0782
Brugia malayi hypothetical protein 0.0157 0.0851 0.1321
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0115 0.0601 0.0934
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0364 0.1087
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.012 0.0632 0.0981
Loa Loa (eye worm) hypothetical protein 0.0076 0.0364 0.0566
Loa Loa (eye worm) hypothetical protein 0.0065 0.0297 0.0462
Echinococcus granulosus glycine receptor subunit beta 0.012 0.0632 0.0981
Onchocerca volvulus 0.0584 0.3422 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0033 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0099 0.0503 0.0782
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0056 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0183 0.101 0.1569
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0028 0.0044
Schistosoma mansoni tar DNA-binding protein 0.0266 0.1508 0.2343
Echinococcus multilocularis acetylcholinesterase 0.1085 0.6436 0.6436
Mycobacterium ulcerans beta-lactamase 0.0076 0.0364 0.3479
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.0105 0.0163
Onchocerca volvulus 0.0152 0.082 0.2397
Onchocerca volvulus 0.0157 0.0851 0.2485
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.0364 0.1226
Schistosoma mansoni cpg binding protein 0.0033 0.0104 0.0161
Loa Loa (eye worm) hypothetical protein 0.0099 0.0503 0.0782
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0183 0.0517
Echinococcus multilocularis integrin alpha ps 0.011 0.0571 0.0571
Loa Loa (eye worm) hypothetical protein 0.0099 0.0503 0.0782
Onchocerca volvulus 0.002 0.0028 0.0083
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0471 0.2743 0.4262
Schistosoma mansoni tar DNA-binding protein 0.0266 0.1508 0.2343
Echinococcus granulosus muscleblind protein 0.0309 0.1766 0.2744
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0471 0.2743 0.4262
Echinococcus granulosus glycine receptor subunit alpha 1 0.012 0.0632 0.0981
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.0364 0.1226
Echinococcus multilocularis nAChR subunit 0.012 0.0632 0.0632
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.012 0.0632 0.0981
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.0105 0.0163
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.0105 0.0163
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0147 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0365 0.2102 0.3267
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Onchocerca volvulus 0.0056 0.0241 0.0704
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.002 0.0522
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0624 0.097
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Entamoeba histolytica Ran family GTPase 0.0024 0.0052 0.1178
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0364 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.0105 0.0163
Onchocerca volvulus 0.0065 0.0297 0.0868
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0028 0.0028
Onchocerca volvulus 0.0183 0.101 0.295
Brugia malayi Bromodomain containing protein 0.0082 0.04 0.0621
Loa Loa (eye worm) RNA binding protein 0.0266 0.1508 0.2343
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0028 0.0028
Echinococcus granulosus glycine receptor subunit beta 0.012 0.0632 0.0981
Brugia malayi excitatory GABA receptor EXP-1A 0.012 0.0632 0.0981
Schistosoma mansoni ran 0.0024 0.0052 0.0081
Loa Loa (eye worm) hypothetical protein 0.0584 0.3422 0.5317
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.0364 0.0566
Schistosoma mansoni nAChR subunit 0.012 0.0632 0.0981
Loa Loa (eye worm) hypothetical protein 0.0052 0.0222 0.0345
Schistosoma mansoni hypothetical protein 0.0115 0.0601 0.0934
Echinococcus multilocularis BC026374 protein (S09 family) 0.0183 0.101 0.101
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0044
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0364 1
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0104 0.0104
Echinococcus multilocularis glycine receptor subunit alpha 1 0.012 0.0632 0.0632
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.0105 0.0163
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.002 0.0522
Trichomonas vaginalis glucosylceramidase, putative 0.0377 0.2175 0.6804
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Loa Loa (eye worm) norepinephrine transporter 0.0584 0.3422 0.5317
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Schistosoma mansoni integrin alpha 0.0246 0.1389 0.2158
Loa Loa (eye worm) hypothetical protein 0.0076 0.0364 0.0566
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.0105 0.0163
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0076 0.0364 0.0566
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0365 0.2102 0.3267
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0099 0.0503 0.0782
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0028 0.0044
Echinococcus granulosus importin subunit beta 1 0.0033 0.0104 0.0162
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.002 0.002
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0104 0.286
Echinococcus multilocularis sodium and chloride dependent glycine 0.0099 0.0503 0.0503
Brugia malayi steroid hormone receptor 0.0033 0.0105 0.0163
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0105 0.0163
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0052 0.0052
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0099 0.0503 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0115 0.0601 0.0601
Trichomonas vaginalis glucosylceramidase, putative 0.0358 0.206 0.6439
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0011 0.0018
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0105 0.0163
Entamoeba histolytica hypothetical protein 0.0027 0.0067 0.1712
Brugia malayi hypothetical protein 0.0183 0.101 0.1569
Loa Loa (eye worm) acetylcholinesterase 1 0.1085 0.6436 1
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.002 0.0028 0.0028
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0545 0.3188 0.4953
Loa Loa (eye worm) acetyltransferase 0.0151 0.0813 0.1263
Onchocerca volvulus 0.012 0.0632 0.1845
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.0105 0.0306
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0099 0.0503 0.0503
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.0105 0.0163
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0065 0.0297 0.0462
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.012 0.0632 0.0632
Onchocerca volvulus 0.0183 0.101 0.295
Loa Loa (eye worm) hypothetical protein 0.0056 0.0241 0.0374
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0183 0.101 0.3523
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0052 0.1421
Loa Loa (eye worm) hypothetical protein 0.0099 0.0503 0.0782
Onchocerca volvulus 0.0029 0.0082 0.0239
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.0364 0.1226
Loa Loa (eye worm) hypothetical protein 0.0065 0.0297 0.0462
Echinococcus granulosus glycine receptor subunit alpha 1 0.012 0.0632 0.0981
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0028 0.0044
Brugia malayi beta-lactamase family protein 0.0076 0.0364 0.0566
Schistosoma mansoni sodium/chloride dependent transporter 0.0099 0.0503 0.0782
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0266 0.1508 0.2343
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0099 0.0503 0.0782
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0011 0.0018
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0028 0.0044
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0183 0.101 0.1569
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0471 0.2743 0.4262
Loa Loa (eye worm) hypothetical protein 0.012 0.0632 0.0981
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0052 0.1421
Onchocerca volvulus 0.0056 0.0241 0.0704
Mycobacterium ulcerans carboxylesterase, LipT 0.0183 0.101 1
Echinococcus granulosus integrin alpha ps 0.011 0.0571 0.0887
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.0105 0.0163
Schistosoma mansoni sodium/chloride dependent transporter 0.0099 0.0503 0.0782
Schistosoma mansoni hypothetical protein 0.0152 0.082 0.1274
Leishmania major GTP-binding protein, putative 0.0024 0.0052 0.1421
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0017
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0011 0.0017
Brugia malayi CXXC zinc finger family protein 0.0029 0.0082 0.0127
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0082 0.0127

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.