Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0246 | 0.7359 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0246 | 0.7359 | 1 |
Onchocerca volvulus | 0.028 | 0.8431 | 1 | |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0179 | 0.5237 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0163 | 0.0461 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0163 | 0.0461 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.07 | 0.106 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0046 | 0.1057 | 0.1762 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.0952 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0035 | 0.0711 | 0.0966 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0157 | 0.4544 | 0.4544 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.07 | 0.0952 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0326 | 0.0444 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.07 | 0.106 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0018 | 0.0163 | 0.0461 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.07 | 0.065 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0046 | 0.1057 | 0.1082 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0046 | 0.1057 | 0.1082 |
Trichomonas vaginalis | hypothetical protein | 0.0179 | 0.5237 | 0.6137 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0013 | 0.0015 | 0.002 |
Trypanosoma brucei | metallo-peptidase, Clan MF, Family M17 | 0.0025 | 0.0388 | 0.1097 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0018 | 0.0163 | 0.0311 |
Plasmodium falciparum | glutathione reductase | 0.0051 | 0.1216 | 0.2076 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.07 | 0.07 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0042 | 0.0936 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0023 | 0.0326 | 0.0623 |
Trypanosoma brucei | aminopeptidase, putative | 0.0025 | 0.0388 | 0.1097 |
Echinococcus granulosus | leucine aminopeptidase protein | 0.0125 | 0.3537 | 0.3537 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.07 | 0.106 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0157 | 0.4544 | 0.4544 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.07 | 0.0952 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0163 | 0.0461 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0152 | 0.4406 | 0.4406 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0381 | 0.1078 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0034 | 0.0676 | 0.0676 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0717 | 0.0974 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0051 | 0.1216 | 0.3438 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0018 | 0.0163 | 0.0247 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0163 | 0.0461 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0717 | 0.0717 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.0952 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0018 | 0.0163 | 0.0311 |
Echinococcus multilocularis | leucyl aminopeptidase | 0.0025 | 0.0388 | 0.0388 |
Brugia malayi | Aminopeptidase W07G4.4 in chromosome V | 0.0025 | 0.0388 | 0.0527 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0163 | 0.0461 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0051 | 0.1216 | 0.1652 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0131 | 0.3729 | 0.5068 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0381 | 0.043 |
Brugia malayi | Cytochrome P450 family protein | 0.0035 | 0.0711 | 0.0966 |
Schistosoma mansoni | thyroid hormone receptor | 0.0149 | 0.4303 | 0.4303 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0018 | 0.0163 | 0.0311 |
Chlamydia trachomatis | cytosol aminopeptidase | 0.0125 | 0.3537 | 0.6649 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0117 | 0.3281 | 0.4966 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0117 | 0.3281 | 0.4966 |
Echinococcus granulosus | ankyrin repeat domain containing protein 17 | 0.0025 | 0.0388 | 0.0388 |
Trichomonas vaginalis | set domain proteins, putative | 0.028 | 0.8431 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0117 | 0.3281 | 0.4966 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.07 | 0.1337 |
Mycobacterium ulcerans | leucyl aminopeptidase | 0.0125 | 0.3537 | 0.6754 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0179 | 0.5237 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.3954 | 0.3954 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.0717 | 0.0717 |
Schistosoma mansoni | hypothetical protein | 0.033 | 1 | 1 |
Echinococcus multilocularis | leucyl aminopeptidase | 0.0025 | 0.0388 | 0.0388 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.07 | 0.07 |
Plasmodium falciparum | thioredoxin reductase | 0.0051 | 0.1216 | 0.2076 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.013 | 0.3691 | 0.7048 |
Toxoplasma gondii | thioredoxin reductase | 0.0051 | 0.1216 | 0.2322 |
Brugia malayi | beta-lactamase | 0.0035 | 0.07 | 0.0952 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0381 | 0.0518 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0179 | 0.5237 | 1 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0179 | 0.5237 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.07 | 0.198 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0717 | 0.0974 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0179 | 0.5237 | 1 |
Trypanosoma brucei | metallo-peptidase, Clan MF, Family M17 | 0.0025 | 0.0388 | 0.1097 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0163 | 0.0461 |
Plasmodium vivax | glutathione reductase, putative | 0.0051 | 0.1216 | 0.2076 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0381 | 0.043 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0138 | 0.3954 | 0.3954 |
Wolbachia endosymbiont of Brugia malayi | leucyl aminopeptidase | 0.0125 | 0.3537 | 0.6649 |
Brugia malayi | MH2 domain containing protein | 0.0131 | 0.3729 | 0.5068 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0042 | 0.0936 | 0.1524 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0157 | 0.4544 | 0.6175 |
Leishmania major | cytochrome p450-like protein | 0.0023 | 0.0326 | 0.0923 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0717 | 0.0717 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0051 | 0.1216 | 0.1216 |
Trypanosoma cruzi | cytosolic leucyl aminopeptidase, putative | 0.0125 | 0.3537 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0051 | 0.1216 | 0.1652 |
Loa Loa (eye worm) | glutathione reductase | 0.0051 | 0.1216 | 0.1652 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.0326 | 0.0923 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.07 | 0.1337 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0025 | 0.0388 | 0.0527 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0018 | 0.0163 | 0.0461 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0106 | 0.0144 |
Echinococcus multilocularis | leucine aminopeptidase protein | 0.0125 | 0.3537 | 0.3537 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0717 | 0.0717 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0046 | 0.1057 | 0.2019 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.07 | 0.106 |
Echinococcus granulosus | leucyl aminopeptidase | 0.0025 | 0.0388 | 0.0388 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 | 0.0025 | 0.0388 | 0.1097 |
Toxoplasma gondii | leucyl aminopeptidase LAP | 0.0125 | 0.3537 | 0.6754 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0381 | 0.0518 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0163 | 0.0461 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0381 | 0.043 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0179 | 0.5237 | 0.7928 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.07 | 0.07 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0222 | 0.6606 | 1 |
Echinococcus granulosus | leucyl aminopeptidase | 0.0025 | 0.0388 | 0.0388 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.07 | 0.106 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0381 | 0.0728 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0117 | 0.3281 | 0.4966 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0163 | 0.0461 |
Treponema pallidum | NADH oxidase | 0.0018 | 0.0163 | 0.5 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0018 | 0.0163 | 0.0221 |
Trypanosoma cruzi | metallo-peptidase, Clan MF, Family M17, putative | 0.0125 | 0.3537 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0018 | 0.0163 | 0.0461 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 | 0.0025 | 0.0388 | 0.1097 |
Schistosoma mansoni | PwLAP aminopeptidase (M17 family) | 0.0025 | 0.0388 | 0.0388 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0163 | 0.0461 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0163 | 0.0461 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.07 | 0.1337 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.07 | 0.065 |
Plasmodium vivax | M17 leucyl aminopeptidase, putative | 0.0125 | 0.3537 | 0.6649 |
Trypanosoma cruzi | metallo-peptidase, Clan MF, Family M17 | 0.0025 | 0.0388 | 0.1097 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0117 | 0.3281 | 0.4966 |
Loa Loa (eye worm) | aminopeptidase in chromosome V | 0.0025 | 0.0388 | 0.0527 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.0952 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.07 | 0.106 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.07 | 0.1337 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.07 | 0.0952 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.07 | 0.106 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.013 | 0.3691 | 0.5587 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.07 | 0.106 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0018 | 0.0163 | 0.0163 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0046 | 0.1057 | 0.1057 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0035 | 0.0717 | 0.0717 |
Echinococcus multilocularis | geminin | 0.033 | 1 | 1 |
Leishmania major | cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 | 0.0125 | 0.3537 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0717 | 0.1092 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0381 | 0.1078 |
Mycobacterium leprae | Probable cytosol aminopeptidase PepB | 0.0125 | 0.3537 | 0.6754 |
Leishmania major | trypanothione reductase | 0.0051 | 0.1216 | 0.3438 |
Loa Loa (eye worm) | acetyltransferase | 0.0157 | 0.4544 | 0.6175 |
Brugia malayi | cytosol aminopeptidase | 0.0025 | 0.0388 | 0.0527 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0051 | 0.1216 | 0.2076 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0179 | 0.5237 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0326 | 0.0444 |
Trypanosoma brucei | cytochrome P450, putative | 0.0023 | 0.0326 | 0.0923 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.07 | 0.065 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.07 | 0.065 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.07 | 0.1337 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.07 | 0.106 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.0952 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.07 | 0.07 |
Onchocerca volvulus | 0.0035 | 0.0717 | 0.0021 | |
Loa Loa (eye worm) | aminopeptidase in chromosome III | 0.0025 | 0.0388 | 0.0527 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.07 | 0.065 |
Echinococcus multilocularis | leucyl aminopeptidase | 0.0025 | 0.0388 | 0.0388 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.0326 | 0.0923 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0023 | 0.0326 | 0.0444 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0326 | 0.0444 |
Schistosoma mansoni | hypothetical protein | 0.033 | 1 | 1 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0018 | 0.0163 | 0.0311 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.07 | 0.1337 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.07 | 0.0952 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.07 | 0.198 |
Plasmodium falciparum | M17 leucyl aminopeptidase | 0.0125 | 0.3537 | 0.6649 |
Brugia malayi | glutathione reductase | 0.0051 | 0.1216 | 0.1652 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0013 | 0.0015 | 0.002 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0018 | 0.0163 | 0.0461 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.07 | 0.1337 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0051 | 0.1216 | 0.1216 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.0952 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0018 | 0.0163 | 0.0311 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.07 | 0.065 |
Mycobacterium tuberculosis | Probable aminopeptidase PepB | 0.0125 | 0.3537 | 0.5354 |
Trypanosoma brucei | metallo-peptidase, Clan MF, Family M17 | 0.0125 | 0.3537 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.0952 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0326 | 0.0444 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0042 | 0.0936 | 0.5 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0046 | 0.1057 | 0.2019 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.07 | 0.198 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0138 | 0.3954 | 0.3954 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0179 | 0.5237 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0163 | 0.0461 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0018 | 0.0163 | 0.0461 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0018 | 0.0163 | 0.0163 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.07 | 0.1059 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0717 | 0.0717 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.07 | 0.1337 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.07 | 0.106 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 | 0.0025 | 0.0388 | 0.1097 |
Trypanosoma brucei | trypanothione reductase | 0.0051 | 0.1216 | 0.3438 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.0717 | 0.1369 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0051 | 0.1216 | 0.1841 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.013 | 0.3691 | 0.5587 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0117 | 0.3281 | 0.6265 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.07 | 0.0952 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0717 | 0.0717 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0149 | 0.4303 | 0.4303 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0163 | 0.0461 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.07 | 0.198 |
Brugia malayi | Aminopeptidase ZK353.6 in chromosome III | 0.0025 | 0.0388 | 0.0527 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0381 | 0.1078 |
Schistosoma mansoni | thyroid hormone receptor | 0.0149 | 0.4303 | 0.4303 |
Schistosoma mansoni | leucine aminopeptidase | 0.0025 | 0.0388 | 0.0388 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0117 | 0.3281 | 0.4966 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0381 | 0.1078 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0131 | 0.3729 | 0.5068 |
Trypanosoma cruzi | metallo-peptidase, Clan MF, Family M17 | 0.0025 | 0.0388 | 0.1097 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.013 | 0.3691 | 0.5587 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0018 | 0.0163 | 0.0163 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.