Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0048 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 1 | 1 |
Onchocerca volvulus | 0.0048 | 0 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.0285 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0285 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0285 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0285 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0032 | 0.0032 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0048 | 0 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0032 | 0.0032 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0048 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0285 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0048 | 0 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0285 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0032 | 0.0032 |
Onchocerca volvulus | 0.0048 | 0 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0285 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0285 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0285 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0048 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0048 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0032 | 0.0032 |
Brugia malayi | Carboxylesterase family protein | 0.0285 | 1 | 1 |
Onchocerca volvulus | 0.0048 | 0 | 0.5 | |
Onchocerca volvulus | 0.0048 | 0 | 0.5 | |
Onchocerca volvulus | 0.0048 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.