Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0017 | 0.0008 | 0.0011 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0238 | 0.357 | 0.4465 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0017 | 0.0008 | 0.0011 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0017 | 0.0008 | 0.0023 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0474 | 0.0592 |
Chlamydia trachomatis | insulinase family protease III | 0.0024 | 0.0126 | 0.5 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0637 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0017 | 0.0008 | 0.0023 |
Leishmania major | cytochrome p450-like protein | 0.0033 | 0.026 | 0.0222 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0033 | 0.026 | 0.0433 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0017 | 0.0008 | 0.0023 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0514 | 0.1386 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.026 | 0.0325 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0008 | 0.0023 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0017 | 0.0008 | 0.0011 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0039 | 0.0048 |
Schistosoma mansoni | nardilysin (M16 family) | 0.0024 | 0.0126 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.357 | 0.9623 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0111 | 0.153 | 0.4123 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0033 | 0.026 | 0.0433 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0042 | 0.0402 | 0.0712 |
Onchocerca volvulus | 0.0049 | 0.0514 | 0.2085 | |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.006 | 0.0702 | 0.0879 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0064 | 0.0766 | 0.0958 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0033 | 0.026 | 0.0433 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0033 | 0.026 | 0.0433 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0017 | 0.0008 | 0.0011 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0474 | 0.0592 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.009 | 0.1175 | 0.1141 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0033 | 0.026 | 0.0433 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0474 | 0.0592 |
Brugia malayi | Cytochrome P450 family protein | 0.0033 | 0.026 | 0.07 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0008 | 0.0023 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0126 | 0.1766 | 0.4761 |
Echinococcus multilocularis | 0.0033 | 0.026 | 0.0325 | |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0039 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0008 | 0.0023 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0637 | 1 | 1 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0033 | 0.026 | 0.0222 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0312 | 0.039 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0064 | 0.0766 | 0.5394 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0033 | 0.026 | 0.0433 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0033 | 0.026 | 0.0433 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0581 | 0.1566 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0033 | 0.026 | 0.0433 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0033 | 0.026 | 0.0433 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0017 | 0.0008 | 0.0023 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0033 | 0.026 | 0.0433 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0033 | 0.026 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0312 | 0.0841 |
Leishmania major | cytochrome p450-like protein | 0.0042 | 0.0402 | 0.0365 |
Brugia malayi | MH2 domain containing protein | 0.0126 | 0.1766 | 0.4761 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0053 | 0.0584 | 0.0731 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0766 | 0.1426 |
Schistosoma mansoni | coup transcription factor | 0.0017 | 0.0008 | 0.0011 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0581 | 0.1566 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0017 | 0.0008 | 0.0011 |
Brugia malayi | Cytochrome P450 family protein | 0.0042 | 0.0402 | 0.1083 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0017 | 0.0008 | 0.0011 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0053 | 0.0584 | 0.0731 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0039 | 0.0104 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0474 | 0.0592 |
Brugia malayi | steroid hormone receptor | 0.0017 | 0.0008 | 0.0023 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.009 | 0.1175 | 0.1141 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0042 | 0.0402 | 0.0365 |
Toxoplasma gondii | hypothetical protein | 0.0103 | 0.1387 | 1 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0033 | 0.026 | 0.0433 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0033 | 0.026 | 0.0433 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0017 | 0.0008 | 0.0023 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0017 | 0.0008 | 0.0023 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.0538 | 0.0502 |
Brugia malayi | mbt repeat family protein | 0.0053 | 0.0584 | 0.1575 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0474 | 0.1277 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.0811 | 0.1014 |
Schistosoma mansoni | insulysin unit 3 (M16 family) | 0.0024 | 0.0126 | 0.0158 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0017 | 0.0008 | 0.0011 |
Echinococcus granulosus | geminin | 0.0512 | 0.7995 | 1 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.006 | 0.0702 | 0.0879 |
Echinococcus granulosus | nardilysin | 0.0024 | 0.0126 | 0.0158 |
Loa Loa (eye worm) | cytochrome P450 | 0.0033 | 0.026 | 0.07 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0252 | 0.068 |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.0268 | 0.4051 | 0.5067 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0126 | 0.1766 | 0.4761 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0301 | 0.4591 | 0.457 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0033 | 0.026 | 0.0433 |
Echinococcus granulosus | 3'partial|nardilysin | 0.0024 | 0.0126 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0702 | 0.1893 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0017 | 0.0008 | 0.0011 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0212 | 0.3155 | 0.3947 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0033 | 0.026 | 0.0433 |
Schistosoma mansoni | nardilysin (M16 family) | 0.0024 | 0.0126 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0008 | 0.0023 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.0538 | 0.0502 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0053 | 0.0584 | 0.0731 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0033 | 0.026 | 0.0433 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.009 | 0.1175 | 0.1141 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0039 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.005 | 0.0538 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0017 | 0.0008 | 0.0023 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0909 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0033 | 0.026 | 0.0222 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0033 | 0.026 | 0.0433 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0064 | 0.0766 | 0.1426 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0017 | 0.0008 | 0.0011 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0017 | 0.0008 | 0.0023 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0033 | 0.026 | 0.0433 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.006 | 0.0702 | 0.0879 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0033 | 0.026 | 0.0222 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0033 | 0.026 | 0.0433 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0017 | 0.0008 | 0.0023 |
Brugia malayi | TAR-binding protein | 0.0067 | 0.0811 | 0.2186 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0017 | 0.0008 | 0.0011 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0042 | 0.0402 | 0.1083 |
Brugia malayi | Cytochrome P450 family protein | 0.0111 | 0.153 | 0.4123 |
Schistosoma mansoni | nuclear hormone receptor | 0.0017 | 0.0008 | 0.0011 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0053 | 0.0584 | 0.0731 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0039 | 0.0048 |
Schistosoma mansoni | hypothetical protein | 0.0512 | 0.7995 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0909 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0766 | 0.0958 |
Brugia malayi | hypothetical protein | 0.005 | 0.0538 | 0.1451 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0008 | 0.0023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0017 | 0.0008 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0581 | 0.1566 |
Loa Loa (eye worm) | MBCTL1 | 0.006 | 0.0702 | 0.1893 |
Mycobacterium ulcerans | hypothetical protein | 0.0335 | 0.514 | 1 |
Schistosoma mansoni | cytochrome P450 | 0.0033 | 0.026 | 0.0325 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0093 | 0.0117 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0766 | 0.1426 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0033 | 0.026 | 0.0433 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0017 | 0.0008 | 0.0011 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0053 | 0.0584 | 0.0731 |
Leishmania major | phosphoglycan beta 1,3 galactosyltransferase 5 | 0.0024 | 0.0126 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0008 | 0.0023 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0073 | 0.0909 | 0.1137 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0474 | 0.0592 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0039 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 0.0811 | 0.2186 |
Schistosoma mansoni | thyroid hormone receptor | 0.0017 | 0.0008 | 0.0011 |
Brugia malayi | hypothetical protein | 0.0168 | 0.2434 | 0.6561 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0033 | 0.026 | 0.0433 |
Brugia malayi | mbt repeat family protein | 0.0053 | 0.0584 | 0.1575 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0017 | 0.0008 | 0.0023 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0033 | 0.026 | 0.0433 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0022 | 0.0093 | 0.0117 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0033 | 0.026 | 0.0222 |
Mycobacterium leprae | putative cytochrome p450 | 0.0033 | 0.026 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.005 | 0.0538 | 0.0502 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.0268 | 0.4051 | 0.5067 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0017 | 0.0008 | 0.0011 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0033 | 0.026 | 0.0433 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0033 | 0.026 | 0.0433 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0017 | 0.0008 | 0.0011 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.0811 | 0.1014 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0033 | 0.026 | 0.0433 |
Toxoplasma gondii | rhoptry metalloprotease toxolysin TLN1 | 0.0024 | 0.0126 | 0.065 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0238 | 0.357 | 0.4465 |
Echinococcus multilocularis | geminin | 0.0512 | 0.7995 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 0.0811 | 0.2186 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0017 | 0.0008 | 0.0011 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.009 | 0.1175 | 0.1141 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0017 | 0.0008 | 0.0023 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0042 | 0.0402 | 0.0365 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0474 | 0.0592 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0042 | 0.0402 | 0.1083 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.0811 | 0.1014 |
Schistosoma mansoni | thyroid hormone receptor | 0.0017 | 0.0008 | 0.0011 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0017 | 0.0008 | 0.0011 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0033 | 0.026 | 0.0433 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0033 | 0.026 | 0.1639 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0909 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0017 | 0.0008 | 0.0011 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0064 | 0.0766 | 0.073 |
Toxoplasma gondii | insulysin, putative | 0.0023 | 0.0107 | 0.0506 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0033 | 0.026 | 0.0433 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0017 | 0.0008 | 0.0011 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0033 | 0.026 | 0.0433 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0474 | 0.1277 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0033 | 0.026 | 0.0433 |
Trypanosoma cruzi | peptidase, putative | 0.0024 | 0.0126 | 0.0088 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0017 | 0.0008 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0538 | 0.1451 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0017 | 0.0008 | 0.0011 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.006 | 0.0702 | 0.1893 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0053 | 0.0584 | 0.0731 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0766 | 0.1426 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0033 | 0.026 | 0.0433 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0017 | 0.0008 | 0.0011 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.005 | 0.0538 | 0.3706 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 0.0811 | 0.2186 |
Loa Loa (eye worm) | hypothetical protein | 0.0247 | 0.371 | 1 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0033 | 0.026 | 0.0433 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0017 | 0.0008 | 0.0023 |
Brugia malayi | nuclear hormone receptor | 0.0017 | 0.0008 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0073 | 0.0909 | 0.2449 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0312 | 0.0841 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0033 | 0.026 | 0.0433 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.0811 | 0.1014 |
Brugia malayi | ecdysteroid receptor | 0.0017 | 0.0008 | 0.0023 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0039 | 0.5 |
Schistosoma mansoni | insulysin unit 3 (M16 family) | 0.0024 | 0.0126 | 0.0158 |
Brugia malayi | hypothetical protein | 0.0238 | 0.357 | 0.9623 |
Schistosoma mansoni | hypothetical protein | 0.0512 | 0.7995 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0033 | 0.026 | 0.0433 |
Echinococcus multilocularis | insulin degrading enzyme | 0.0024 | 0.0126 | 0.0158 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0301 | 0.4591 | 0.457 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0073 | 0.0909 | 0.1137 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0109 | 0.1491 | 0.1458 |
Echinococcus granulosus | insulin degrading enzyme | 0.0024 | 0.0126 | 0.0158 |
Echinococcus multilocularis | nardilysin | 0.0024 | 0.0126 | 0.0158 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0017 | 0.0008 | 0.0011 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0017 | 0.0008 | 0.0023 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0033 | 0.026 | 0.0433 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0017 | 0.0008 | 0.0011 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0039 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.0811 | 0.1014 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0017 | 0.0008 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0584 | 0.1575 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0033 | 0.026 | 0.0433 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0514 | 0.0643 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0017 | 0.0008 | 0.0011 |
Trypanosoma cruzi | peptidase, putative | 0.0024 | 0.0126 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.2434 | 0.6561 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 0.0811 | 0.2186 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0033 | 0.026 | 0.0433 |
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 0.0811 | 0.1014 |
Onchocerca volvulus | 0.0053 | 0.0584 | 0.2374 | |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0017 | 0.0008 | 0.0011 |
Brugia malayi | Cytochrome P450 family protein | 0.0042 | 0.0402 | 0.1083 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0053 | 0.0584 | 0.1575 |
Brugia malayi | nuclear receptor NHR-88 | 0.0017 | 0.0008 | 0.0023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0017 | 0.0008 | 0.0023 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0474 | 0.0592 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.005 | 0.0538 | 0.0502 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0039 | 0.0048 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0033 | 0.026 | 0.0433 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0039 | 0.0048 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.0538 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0042 | 0.0402 | 0.1083 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0033 | 0.026 | 0.0222 |
Echinococcus granulosus | FTZ F1 alpha | 0.0017 | 0.0008 | 0.0011 |
Trypanosoma brucei | peptidase, putative | 0.0024 | 0.0126 | 0.0088 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0033 | 0.026 | 0.0325 |
Echinococcus multilocularis | nardilysin | 0.0024 | 0.0126 | 0.0158 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0033 | 0.026 | 0.0433 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0033 | 0.026 | 0.0433 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0581 | 0.1566 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0335 | 0.514 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0325 | 0.498 | 0.6228 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0909 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0017 | 0.0008 | 0.0011 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0017 | 0.0008 | 0.0023 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0017 | 0.0008 | 0.0023 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0017 | 0.0008 | 0.0011 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0017 | 0.0008 | 0.0023 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0766 | 0.0958 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0909 | 0.1137 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.0538 | 1 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.006 | 0.0702 | 0.0879 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.006 | 0.0702 | 0.0879 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0073 | 0.0909 | 0.1137 |
Brugia malayi | insulin-degrading enzyme | 0.0024 | 0.0126 | 0.0341 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0301 | 0.4591 | 0.457 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0033 | 0.026 | 0.0222 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0514 | 0.0643 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0212 | 0.3155 | 0.3947 |
Trypanosoma brucei | cytochrome P450, putative | 0.0042 | 0.0402 | 0.0365 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0022 | 0.0093 | 0.0117 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0017 | 0.0008 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0008 | 0.0023 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0033 | 0.026 | 0.0433 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0017 | 0.0008 | 0.0023 |
Onchocerca volvulus | 0.0168 | 0.2434 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0017 | 0.0008 | 0.0023 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0053 | 0.0584 | 0.0731 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0247 | 0.371 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0017 | 0.0008 | 0.0011 |
Brugia malayi | cytochrome P450 | 0.0033 | 0.026 | 0.07 |
Toxoplasma gondii | sporozoite developmental protein | 0.0024 | 0.0126 | 0.065 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0033 | 0.026 | 0.0433 |
Brugia malayi | RNA binding protein | 0.0067 | 0.0811 | 0.2186 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0064 | 0.0766 | 0.0958 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0053 | 0.0584 | 0.2374 |
Loa Loa (eye worm) | insulin-degrading enzyme | 0.0024 | 0.0126 | 0.0341 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 0.0811 | 0.1014 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0637 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0039 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.