Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.3224 | 0.3224 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.1841 | 0.55 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.1841 | 0.55 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.3348 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.3348 | 0.3348 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.3348 | 0.3348 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.3224 | 0.3224 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.3348 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.3224 | 0.3224 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.3348 | 0.0183 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.3348 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.3348 | 0.0183 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.3224 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.3348 | 0.3348 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.3348 | 1 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.3224 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.3224 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.3348 | 0.0183 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.3348 | 0.3348 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.3348 | 0.0183 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.3224 | 0.3224 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.3348 | 0.3348 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.3348 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.3348 | 0.0183 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.3224 | 1 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.3348 | 0.3348 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.1841 | 0.55 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.3348 | 0.3348 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.3224 | 0.963 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.3224 | 0.963 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.3348 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.1841 | 0.55 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.3224 | 0.5 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.3224 | 0.963 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.3224 | 0.963 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.3348 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.3224 | 0.963 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.3348 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.3348 | 0.0183 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.3224 | 0.963 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.1841 | 0.55 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.