Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.008 | 0.2924 | 0.2924 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Leishmania major | cathepsin L-like protease | 0.008 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0065 | 0.1716 | 0.5868 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.008 | 0.2924 | 0.2924 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.008 | 0.2924 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.008 | 0.2924 | 0.2924 |
Giardia lamblia | Cathepsin B precursor | 0.0065 | 0.1716 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.008 | 0.2924 | 1 |
Echinococcus granulosus | cathepsin b | 0.0169 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.008 | 0.2924 | 1 |
Onchocerca volvulus | 0.008 | 0.2924 | 1 | |
Onchocerca volvulus | 0.008 | 0.2924 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0065 | 0.1716 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Echinococcus multilocularis | cysteine protease | 0.008 | 0.2924 | 0.2924 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0055 | 0.093 | 0.093 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Leishmania major | cathepsin L-like protease | 0.008 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.2924 | 0.2198 |
Loa Loa (eye worm) | cysteine protease | 0.008 | 0.2924 | 0.2198 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.2924 | 1 |
Onchocerca volvulus | 0.008 | 0.2924 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0055 | 0.093 | 0.3182 |
Onchocerca volvulus | 0.008 | 0.2924 | 1 | |
Loa Loa (eye worm) | ctsf protein | 0.008 | 0.2924 | 0.2198 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0065 | 0.1716 | 0.5868 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.008 | 0.2924 | 0.2924 |
Giardia lamblia | Cathepsin B precursor | 0.0065 | 0.1716 | 0.5 |
Onchocerca volvulus | 0.008 | 0.2924 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.008 | 0.2924 | 0.2924 |
Onchocerca volvulus | Cathepsin L homolog | 0.008 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0169 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.008 | 0.2924 | 0.2924 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0065 | 0.1716 | 0.1716 |
Leishmania major | cathepsin L-like protease | 0.008 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.2924 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0055 | 0.093 | 0.093 |
Brugia malayi | Cathepsin L-like precursor | 0.008 | 0.2924 | 0.2924 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.008 | 0.2924 | 0.2198 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.008 | 0.2924 | 0.2924 |
Brugia malayi | Cathepsin L-like precursor | 0.008 | 0.2924 | 0.2924 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0055 | 0.093 | 0.093 |
Echinococcus multilocularis | cathepsin b | 0.0169 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.008 | 0.2924 | 0.2924 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.008 | 0.2924 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0055 | 0.093 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.2924 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.008 | 0.2924 | 0.2924 |
Onchocerca volvulus | 0.008 | 0.2924 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.008 | 0.2924 | 0.2924 |
Leishmania major | cysteine peptidase A (CPA) | 0.008 | 0.2924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0055 | 0.093 | 0.093 |
Echinococcus multilocularis | cysteine protease | 0.008 | 0.2924 | 0.2924 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.008 | 0.2924 | 0.2198 |
Brugia malayi | Cathepsin L-like precursor | 0.0055 | 0.093 | 0.093 |
Plasmodium vivax | vivapain-2 | 0.008 | 0.2924 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0169 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.2924 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.008 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0065 | 0.1716 | 0.1716 |
Leishmania major | cathepsin L-like protease | 0.008 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.2924 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.008 | 0.2924 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0055 | 0.093 | 0.093 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.008 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.008 | 0.2924 | 0.2924 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.008 | 0.2924 | 0.2924 |
Echinococcus granulosus | cathepsin l1 | 0.008 | 0.2924 | 0.2924 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.008 | 0.2924 | 0.2924 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0055 | 0.093 | 0.093 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.008 | 0.2924 | 0.2924 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.008 | 0.2924 | 0.2924 |
Loa Loa (eye worm) | fibroinase | 0.008 | 0.2924 | 0.2198 |
Leishmania major | cathepsin L-like protease | 0.008 | 0.2924 | 1 |
Leishmania major | cathepsin L-like protease | 0.008 | 0.2924 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.008 | 0.2924 | 0.2924 |
Loa Loa (eye worm) | cathepsin B | 0.0065 | 0.1716 | 0.0866 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.008 | 0.2924 | 0.2924 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.2924 | 1 |
Onchocerca volvulus | 0.008 | 0.2924 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0055 | 0.093 | 0.3182 |
Entamoeba histolytica | cysteine proteinase, putative | 0.008 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.2924 | 1 |
Leishmania major | cathepsin L-like protease | 0.008 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.008 | 0.2924 | 1 |
Leishmania major | cathepsin L-like protease | 0.008 | 0.2924 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.008 | 0.2924 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.008 | 0.2924 | 0.2924 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0169 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.008 | 0.2924 | 1 |
Echinococcus granulosus | cathepsin b | 0.0169 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.