Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 0.0172 | 0.0204 |
Schistosoma mansoni | hypothetical protein | 0.0735 | 0.8441 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0046 | 0.0251 | 0.0297 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0411 | 0.4582 | 1 |
Echinococcus multilocularis | geminin | 0.0735 | 0.8441 | 0.8441 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0251 | 0.0547 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 0.0172 | 0.0204 |
Echinococcus multilocularis | tar DNA binding protein | 0.0411 | 0.4582 | 0.4582 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0172 | 0.5 |
Echinococcus multilocularis | GPCR, family 2 | 0.0046 | 0.0251 | 0.0251 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0375 | 0.4161 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0046 | 0.0251 | 0.0297 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0046 | 0.0251 | 0.0251 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0046 | 0.0251 | 0.0547 |
Schistosoma mansoni | tar DNA-binding protein | 0.0411 | 0.4582 | 0.5428 |
Echinococcus granulosus | tar DNA binding protein | 0.0411 | 0.4582 | 0.5428 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0172 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0147 | 0.1442 | 0.3148 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0251 | 0.0297 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0046 | 0.0251 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0921 | 0.2011 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0251 | 0.0297 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.01 | 0.0891 | 0.1944 |
Loa Loa (eye worm) | TAR-binding protein | 0.0411 | 0.4582 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0251 | 0.0297 |
Echinococcus multilocularis | tumor protein p63 | 0.0703 | 0.805 | 0.805 |
Brugia malayi | TAR-binding protein | 0.0411 | 0.4582 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0375 | 0.4161 | 0.9082 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0372 | 0.4115 | 0.8982 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.1442 | 0.3148 |
Brugia malayi | RNA binding protein | 0.0411 | 0.4582 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0891 | 0.1944 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0103 | 0.0921 | 0.1092 |
Loa Loa (eye worm) | RNA binding protein | 0.0411 | 0.4582 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0046 | 0.0251 | 0.0547 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 0.0172 | 0.0172 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0411 | 0.4582 | 1 |
Echinococcus granulosus | geminin | 0.0735 | 0.8441 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0411 | 0.4582 | 0.5428 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0172 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.0891 | 0.1055 |
Brugia malayi | hypothetical protein | 0.004 | 0.0172 | 0.0376 |
Schistosoma mansoni | hypothetical protein | 0.0735 | 0.8441 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0046 | 0.0251 | 0.0251 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0172 | 0.0204 |
Echinococcus granulosus | tumor protein p63 | 0.0703 | 0.805 | 0.9538 |
Schistosoma mansoni | tar DNA-binding protein | 0.0411 | 0.4582 | 0.5428 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0372 | 0.4115 | 0.8982 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0172 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0251 | 0.0297 |
Brugia malayi | MH2 domain containing protein | 0.0372 | 0.4115 | 0.8982 |
Schistosoma mansoni | tar DNA-binding protein | 0.0411 | 0.4582 | 0.5428 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0147 | 0.1442 | 0.3148 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0147 | 0.1442 | 0.3148 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0046 | 0.0251 | 0.0547 |
Schistosoma mansoni | tar DNA-binding protein | 0.0411 | 0.4582 | 0.5428 |
Loa Loa (eye worm) | hypothetical protein | 0.0375 | 0.4161 | 0.9082 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.