Detailed information for compound 1145904

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 290.697 | Formula: C12H15ClO6
  • H donors: 4 H acceptors: 4 LogP: 0.39 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1O[C@H](Oc2ccccc2Cl)[C@H]([C@H]([C@@H]1O)O)O
  • InChi: 1S/C12H15ClO6/c13-6-3-1-2-4-7(6)18-12-11(17)10(16)9(15)8(5-14)19-12/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11+,12+/m1/s1
  • InChiKey: XVRYBMZGZZIPJY-GCHJQGSQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi jmjC domain containing protein 0.0096 0.5322 0.7788
Schistosoma mansoni tar DNA-binding protein 0.0063 0.3289 0.3289
Loa Loa (eye worm) ctsf protein 0.0017 0.0354 0.0518
Leishmania major cathepsin L-like protease 0.0017 0.0354 0.0811
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.3364 0.7784
Brugia malayi Hexokinase family protein 0.0025 0.0842 0.1232
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0281 0.0281
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0004 0.0011
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.301 0.6964
Leishmania major cathepsin L-like protease 0.0017 0.0354 0.0811
Echinococcus multilocularis peregrin 0.0029 0.1127 0.1123
Schistosoma mansoni chromobox protein 0.007 0.3689 0.3689
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0116 0.0116
Onchocerca volvulus 0.0017 0.0354 0.082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.3364 0.7784
Schistosoma mansoni hexokinase 0.008 0.4321 0.4321
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0004 0.00000000022981
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0354 0.035
Brugia malayi SET domain containing protein 0.0011 0.0004 0.0006
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.2436 0.3565
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0354 0.096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Echinococcus granulosus intermediate filament protein 0.0027 0.1008 0.1008
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.1849 0.1846
Echinococcus granulosus hexokinase type 2 0.008 0.4321 0.4321
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0354 0.0518
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Schistosoma mansoni lamin 0.0027 0.1008 0.1008
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0011
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0469 0.1076
Brugia malayi intermediate filament protein 0.0027 0.1008 0.1475
Echinococcus granulosus chromobox protein 1 0.007 0.3689 0.3689
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0354 0.0354
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0011
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.5322 0.532
Loa Loa (eye worm) hexokinase type II 0.008 0.4321 0.6322
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.3364 0.7784
Onchocerca volvulus 0.0011 0.0004 0.001
Schistosoma mansoni hypothetical protein 0.0016 0.0281 0.0281
Loa Loa (eye worm) fibroinase 0.0017 0.0354 0.0518
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.1753 0.4751
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.2491 0.5761
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0004 0.0011
Brugia malayi hexokinase type II 0.0025 0.0885 0.1294
Entamoeba histolytica cysteine protease, putative 0.0017 0.0354 0.082
Onchocerca volvulus 0.008 0.4321 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.001
Trichomonas vaginalis chromobox protein, putative 0.0042 0.1941 0.526
Echinococcus multilocularis lamin 0.0027 0.1008 0.1004
Schistosoma mansoni jumonji domain containing protein 0.0076 0.4081 0.4081
Schistosoma mansoni hypothetical protein 0.0016 0.0281 0.0281
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0354 0.0811
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.3364 0.7784
Loa Loa (eye worm) helicase 0.0011 0.0004 0.0006
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0207 0.0303
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0004 0.0011
Brugia malayi RNA binding protein 0.0063 0.3289 0.4813
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.1008 0.1475
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0354 0.035
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0185 0.0418
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0004 0.00000000053219
Echinococcus multilocularis chromobox protein 1 0.007 0.3689 0.3687
Echinococcus granulosus Chromo domain 0.0011 0.0004 0.0004
Onchocerca volvulus 0.008 0.4321 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.1127 0.1127
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0004 0.0011
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.2436 0.3565
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0011
Onchocerca volvulus 0.0017 0.0354 0.082
Brugia malayi MH2 domain containing protein 0.0119 0.6834 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0354 0.0354
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.3364 0.7784
Schistosoma mansoni chromobox protein 0.007 0.3689 0.3689
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0116 0.0111
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.1941 0.4491
Loa Loa (eye worm) hypothetical protein 0.0054 0.2719 0.3979
Loa Loa (eye worm) hypothetical protein 0.0013 0.0084 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0354 0.096
Schistosoma mansoni hypothetical protein 0.017 1 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.1127 0.1123
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0354 0.096
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0354 0.096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.3364 0.7784
Onchocerca volvulus Hexokinase homolog 0.005 0.2443 0.5655
Brugia malayi Cathepsin L-like precursor 0.0017 0.0354 0.0518
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0011
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0354 0.0518
Plasmodium falciparum phd finger protein, putative 0.0029 0.1127 0.2601
Brugia malayi Bromodomain containing protein 0.0029 0.1127 0.1649
Entamoeba histolytica hypothetical protein 0.0011 0.0004 0.001
Trypanosoma brucei hexokinase 0.008 0.4321 1
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.309 0.4522
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.3364 0.7784
Onchocerca volvulus 0.0011 0.0004 0.001
Schistosoma mansoni tar DNA-binding protein 0.0063 0.3289 0.3289
Loa Loa (eye worm) hypothetical protein 0.0029 0.1127 0.1649
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.0004 0.0006
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0011 0.0004 0.00000000022981
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0011
Brugia malayi TAR-binding protein 0.0063 0.3289 0.4813
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.1515 0.2217
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0354 0.082
Onchocerca volvulus Alhambra homolog 0.0029 0.1127 0.2608
Entamoeba histolytica hexokinase 2 0.008 0.4321 1
Echinococcus granulosus hexokinase 0.008 0.4321 0.4321
Loa Loa (eye worm) hypothetical protein 0.0013 0.0084 0.0123
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.1008 0.1475
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0633 0.0926
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0006
Onchocerca volvulus 0.005 0.2443 0.5655
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.1438 0.2105
Trichomonas vaginalis chromobox protein, putative 0.0042 0.1941 0.526
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0354 0.096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.3364 0.7784
Echinococcus multilocularis lamin dm0 0.0027 0.1008 0.1004
Echinococcus multilocularis cysteine protease 0.0017 0.0354 0.035
Schistosoma mansoni tar DNA-binding protein 0.0063 0.3289 0.3289
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.6834 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0011 0.0004 0.0004
Brugia malayi Cathepsin L-like precursor 0.0017 0.0354 0.0518
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0004 0.00000000053219
Trypanosoma cruzi hexokinase, putative 0.008 0.4321 1
Echinococcus multilocularis hexokinase 0.008 0.4321 0.4318
Onchocerca volvulus 0.008 0.4321 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0354 0.035
Schistosoma mansoni tar DNA-binding protein 0.0063 0.3289 0.3289
Echinococcus granulosus bloom syndrome protein 0.0021 0.0633 0.0633
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0354 0.096
Trypanosoma brucei hexokinase, putative 0.008 0.4321 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0633 0.1714
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0004 0.00000000053219
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0281 0.0277
Brugia malayi hexokinase 0.008 0.4321 0.6322
Schistosoma mansoni hypothetical protein 0.0029 0.1127 0.1127
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0354 0.0811
Schistosoma mansoni hypothetical protein 0.0016 0.0281 0.0281
Schistosoma mansoni hypothetical protein 0.017 1 1
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0004 0.0011
Echinococcus multilocularis GPCR, family 2 0.0016 0.0281 0.0277
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0281 0.0411
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0011
Echinococcus multilocularis musashi 0.0027 0.1008 0.1004
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.1032 0.2797
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0011
Toxoplasma gondii cathepsin CPL 0.0017 0.0354 0.0811
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.1515 0.1515
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0011
Onchocerca volvulus 0.0017 0.0354 0.082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Toxoplasma gondii hexokinase 0.008 0.4321 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0354 0.035
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0011 0.0004 0.0004
Echinococcus granulosus hexokinase 0.008 0.4321 0.4321
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.1127 0.1649
Brugia malayi jmjC domain containing protein 0.0035 0.1515 0.2217
Plasmodium vivax hypothetical protein, conserved 0.0029 0.1127 0.2601
Echinococcus granulosus tar DNA binding protein 0.0063 0.3289 0.3289
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.3364 0.7784
Echinococcus granulosus Chromobox protein 3 0.0011 0.0004 0.0004
Loa Loa (eye worm) intermediate filament protein 0.0027 0.1008 0.1475
Entamoeba histolytica hypothetical protein 0.0011 0.0004 0.001
Leishmania major cathepsin L-like protease 0.0017 0.0354 0.0811
Schistosoma mansoni hypothetical protein 0.0016 0.0281 0.0281
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.1515 0.1511
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Leishmania major hexokinase, putative 0.008 0.4321 1
Onchocerca volvulus 0.0031 0.1219 0.2822
Loa Loa (eye worm) hypothetical protein 0.0017 0.0354 0.0518
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0195 0.0443
Brugia malayi Hexokinase family protein 0.008 0.4321 0.6322
Echinococcus multilocularis cysteine protease 0.0017 0.0354 0.035
Echinococcus multilocularis Chromo domain 0.0011 0.0004 0.00000000022981
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0354 0.082
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0011
Entamoeba histolytica hypothetical protein 0.0011 0.0004 0.001
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0004 0.0009
Schistosoma mansoni chromobox protein 0.0011 0.0004 0.0004
Schistosoma mansoni tar DNA-binding protein 0.0063 0.3289 0.3289
Echinococcus multilocularis hexokinase type 2 0.008 0.4321 0.4318
Echinococcus granulosus lamin dm0 0.0027 0.1008 0.1008
Trypanosoma cruzi hexokinase, putative 0.008 0.4321 1
Leishmania major cathepsin L-like protease 0.0017 0.0354 0.0811
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.1515 0.1515
Echinococcus granulosus peregrin 0.0029 0.1127 0.1127
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) hexokinase 0.008 0.4321 0.6322
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0011
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0354 0.082
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0004 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0885 0.1294
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0207 0.0303
Echinococcus multilocularis hexokinase 0.008 0.4321 0.4318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0006
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.3289 0.4813
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0011
Loa Loa (eye worm) hexokinase 0.008 0.4321 0.6322
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0354 0.096
Loa Loa (eye worm) hypothetical protein 0.0027 0.0977 0.1429
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0354 0.0811
Brugia malayi Cathepsin L-like precursor 0.0017 0.0354 0.0518
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.3364 0.7784
Trichomonas vaginalis chromobox protein, putative 0.007 0.3689 1
Brugia malayi Hexokinase family protein 0.005 0.2443 0.3575
Echinococcus granulosus cathepsin l1 0.0017 0.0354 0.0354
Echinococcus multilocularis geminin 0.017 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.3364 0.7784
Onchocerca volvulus 0.0017 0.0354 0.082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0354 0.096
Leishmania major cathepsin L-like protease 0.0065 0.3364 0.7784
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.3364 0.7784
Echinococcus multilocularis tar DNA binding protein 0.0063 0.3289 0.3287
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0011
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.1127 0.1127
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.2436 0.3565
Trichomonas vaginalis hypothetical protein 0.0011 0.0004 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0281 0.0411
Loa Loa (eye worm) hypothetical protein 0.0034 0.1438 0.2105
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0354 0.082
Brugia malayi chromobox protein homolog 3 0.0039 0.1753 0.2565
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0004 0.0006
Onchocerca volvulus 0.0027 0.1008 0.2333
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.1753 0.4057
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0354 0.0811
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.1127 0.2601
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0004 0.0011
Plasmodium vivax vivapain-2 0.0017 0.0354 0.0811
Onchocerca volvulus 0.0027 0.1008 0.2333
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0359 0.0526
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0006
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0354 0.0811
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0885 0.1294
Loa Loa (eye worm) hexokinase 0.0025 0.0842 0.1232
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.5322 0.5322
Loa Loa (eye worm) hexokinase 0.005 0.2443 0.3575
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.3689 0.5399
Entamoeba histolytica hexokinase 1 0.008 0.4321 1
Brugia malayi CHD4 protein 0.0011 0.0004 0.0006
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0004 0.0006
Onchocerca volvulus 0.0017 0.0354 0.082
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0281 0.0277
Onchocerca volvulus 0.0017 0.0354 0.082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.3364 0.7784
Trichomonas vaginalis chromobox protein, putative 0.007 0.3689 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.3289 0.4813
Echinococcus granulosus jumonji domain containing protein 0.0041 0.1849 0.1849
Loa Loa (eye worm) TAR-binding protein 0.0063 0.3289 0.4813
Loa Loa (eye worm) hypothetical protein 0.0016 0.0281 0.0411
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.001
Loa Loa (eye worm) RecQ helicase 0.0021 0.0633 0.0926
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.3364 0.7784
Loa Loa (eye worm) hypothetical protein 0.0039 0.1753 0.2565
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0354 0.096
Echinococcus granulosus hexokinase 0.008 0.4321 0.4321
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0011
Echinococcus multilocularis chromobox protein 1 0.007 0.3689 0.3687
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.1127 0.2601
Echinococcus granulosus lamin 0.0027 0.1008 0.1008
Onchocerca volvulus 0.0011 0.0004 0.001
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.3364 0.7784
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0354 0.0354
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.001
Onchocerca volvulus 0.0017 0.0354 0.082
Plasmodium vivax vivapain-2 0.0017 0.0354 0.0811
Brugia malayi Heterochromatin protein 1 0.007 0.3689 0.5399
Leishmania major hexokinase, putative 0.008 0.4321 1
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0633 0.0629
Echinococcus multilocularis hexokinase 0.008 0.4321 0.4318
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.6834 1
Trypanosoma brucei hexokinase 0.008 0.4321 1
Brugia malayi Cathepsin L-like precursor 0.0017 0.0354 0.0518
Brugia malayi Cathepsin L-like precursor 0.0017 0.0354 0.0518
Loa Loa (eye worm) hypothetical protein 0.0013 0.0116 0.0169
Brugia malayi hypothetical protein 0.0011 0.0004 0.0006
Brugia malayi Cathepsin L-like precursor 0.0017 0.0354 0.0518
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0281 0.0281
Leishmania major cathepsin L-like protease 0.0065 0.3364 0.7784
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0354 0.082
Loa Loa (eye worm) hypothetical protein 0.005 0.2444 0.3577
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0281 0.0411
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0004 0.0011
Schistosoma mansoni intermediate filament proteins 0.0027 0.1008 0.1008
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0011
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.1515 0.1515
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0354 0.096
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0354 0.0518
Plasmodium vivax hexokinase, putative 0.008 0.4321 1
Plasmodium falciparum hexokinase 0.008 0.4321 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0354 0.096
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0004 0.0004
Brugia malayi PHD-finger family protein 0.0029 0.1127 0.1649
Schistosoma mansoni hypothetical protein 0.0034 0.1438 0.1438
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0004 0.0011
Giardia lamblia PHD finger protein 15 0.0029 0.1127 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Echinococcus granulosus chromobox protein 1 0.007 0.3689 0.3689
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0006
Brugia malayi Protein cec-1. 0.0011 0.0004 0.0006
Treponema pallidum hexokinase (hxk) 0.008 0.4321 0.5
Loa Loa (eye worm) cysteine protease 0.0017 0.0354 0.0518
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0633 0.1714
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Leishmania major cathepsin L-like protease 0.0065 0.3364 0.7784
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0354 0.096
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.1032 0.2797
Echinococcus granulosus GPCR family 2 0.0016 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0027 0.1008 0.1475
Schistosoma mansoni lamin 0.0027 0.1008 0.1008
Loa Loa (eye worm) hypothetical protein 0.0031 0.1219 0.1784
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0349 0.0349
Leishmania major cathepsin L-like protease 0.0017 0.0354 0.0811
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.0011 0.0004 0.0004
Echinococcus granulosus chromobox protein 2 0.0011 0.0004 0.0004
Schistosoma mansoni chromobox protein 0.0011 0.0004 0.0004
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0354 0.0354
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.1753 0.4751
Loa Loa (eye worm) hypothetical protein 0.005 0.2436 0.3565
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) RNA binding protein 0.0063 0.3289 0.4813
Loa Loa (eye worm) CHromoDomain protein family member 0.0011 0.0004 0.0006

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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