Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.2467 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.6906 | 0.3913 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.4917 | 0.3252 |
Brugia malayi | hypothetical protein | 0.0041 | 0.6906 | 0.6906 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.2467 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0041 | 0.6906 | 0.3913 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.2467 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0025 | 0.2467 | 0.2467 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.4917 | 0.4917 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.9273 | 0.9273 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.6906 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.6906 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.2467 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.6906 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.2467 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.2467 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.9273 | 0.9273 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.6906 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.2467 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.9273 | 0.9034 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.2467 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.9273 | 0.9034 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.