Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | bromodomain containing protein | 0.0071 | 0.3552 | 0.5375 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0112 | 0.6608 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.4172 | 0.6437 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0047 | 0.18 | 0.1668 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.18 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.1674 | 0.2583 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.011 | 0.6481 | 0.6424 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0047 | 0.18 | 0.1668 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1477 | 0.2279 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.011 | 0.6481 | 0.5 |
Echinococcus multilocularis | expressed conserved protein | 0.0104 | 0.5984 | 0.5919 |
Echinococcus multilocularis | protein dispatched 1 | 0.0054 | 0.2298 | 0.2173 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.1274 | 0.1133 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.18 | 0.2778 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1833 | 0.2829 |
Echinococcus multilocularis | protein patched | 0.0047 | 0.18 | 0.1668 |
Brugia malayi | Bromodomain containing protein | 0.0043 | 0.1471 | 0.1821 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0047 | 0.18 | 0.2778 |
Schistosoma mansoni | patched 1 | 0.0047 | 0.18 | 0.2724 |
Echinococcus granulosus | expressed conserved protein | 0.0104 | 0.5984 | 0.5919 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.6481 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.2592 | 0.3999 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.011 | 0.6481 | 0.6424 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0158 | 1 | 1 |
Brugia malayi | CHE-14 protein | 0.0047 | 0.18 | 0.2358 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.1673 | 0.2532 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0047 | 0.18 | 0.1668 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0067 | 0.3254 | 0.3145 |
Brugia malayi | Bromodomain containing protein | 0.0084 | 0.4528 | 0.6811 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.1673 | 0.2532 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0067 | 0.3254 | 0.3145 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.1673 | 0.2532 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.011 | 0.6481 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.1673 | 0.2532 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.0159 | 0.0241 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.1274 | 0.1133 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.