Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.042 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.2036 | 0.1318 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.2036 | 0.1318 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.2036 | 0.1318 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.8854 | 1 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0017 | 0.2324 | 0.1971 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.963 | 0.9683 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4619 | 0.4619 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.042 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.006 | 0.9918 | 0.9918 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0839 | 0.0339 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.042 | 0.5 |
Schistosoma mansoni | jumonji domain containing protein | 0.0059 | 0.963 | 0.963 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0016 | 0.2036 | 0.2036 |
Schistosoma mansoni | jumonji domain containing protein | 0.0016 | 0.2036 | 0.2036 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.042 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4619 | 0.4619 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.4331 | 0.3846 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.2036 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.9918 | 1 |
Echinococcus multilocularis | phd:f box containing protein | 0.0016 | 0.2036 | 0.1654 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.4331 | 0.4331 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0016 | 0.2036 | 0.1654 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.4619 | 0.4355 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0016 | 0.2036 | 0.1603 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.2036 | 0.1337 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0016 | 0.2036 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.042 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.042 | 0.5 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0839 | 0.0328 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0016 | 0.2036 | 0.2036 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.2036 | 0.1318 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.2036 | 0.1337 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.2036 | 0.1318 |
Onchocerca volvulus | 0.0029 | 0.4331 | 0.5 | |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.4619 | 0.4493 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.042 | 0.5 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0531 | 0.0531 |
Echinococcus granulosus | phd:f box containing protein | 0.0016 | 0.2036 | 0.1603 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.042 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.042 | 0.5 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0059 | 0.963 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.006 | 0.9918 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.042 | 0.5 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.042 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.042 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.2036 | 0.1337 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0016 | 0.2036 | 0.1603 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.042 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.2036 | 0.1318 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0016 | 0.2036 | 0.1654 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0059 | 0.963 | 1 |
Plasmodium vivax | JmjC domain containing protein | 0.0016 | 0.2036 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.9918 | 1 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0016 | 0.2036 | 0.5 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0059 | 0.963 | 0.9693 |
Schistosoma mansoni | protein phosphatase 2C | 0.0016 | 0.2036 | 0.2036 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.042 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.042 | 0.5 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0016 | 0.2036 | 0.1654 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0016 | 0.2036 | 0.1603 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0017 | 0.2324 | 0.1911 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.042 | 0.5 |
Schistosoma mansoni | phd/f-box containing protein | 0.0016 | 0.2036 | 0.2036 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.2036 | 0.1337 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0016 | 0.2036 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.006 | 0.9918 | 0.9918 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.042 | 0.5 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0016 | 0.2036 | 0.5 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.4331 | 0.386 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.042 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.