Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0071 | 0.0199 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.8869 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0651 | 0.1257 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.268 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | skeletal muscle/kidney enriched inositol 5-phosphatase, putative | 0.0004 | 0.0071 | 0.0199 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0651 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Plasmodium falciparum | DNase I-like protein, putative | 0.0004 | 0.0071 | 0.0265 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0651 | 0.1257 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.1916 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.268 | 1 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Plasmodium falciparum | endonuclease/exonuclease/phosphatase family protein, putative | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | neutral sphingomyelinase | 0.0004 | 0.0071 | 0.0071 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0127 | 0.0127 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.268 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4403 | 0.4403 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | Phospholipase C precursor, putative | 0.0004 | 0.0071 | 0.0199 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0936 | 0.1996 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4688 | 0.4688 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.268 | 0.5 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase domain containing protein | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | carbon catabolite repressor protein | 0.0004 | 0.0071 | 0.0071 |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0004 | 0.0071 | 0.0265 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | type II inositol 5-phosphatase, putative | 0.0004 | 0.0071 | 0.0199 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | nocturnin | 0.0004 | 0.0071 | 0.0071 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.268 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Schistosoma mansoni | ocrl type II inositol 5-phosphatase | 0.0004 | 0.0071 | 0.0071 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0071 | 0.0199 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0651 | 0.1257 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.4688 | 1 |
Onchocerca volvulus | 0.0031 | 0.4403 | 1 | |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | cript-related | 0.0004 | 0.0071 | 0.0071 |
Schistosoma mansoni | synaptojanin | 0.0004 | 0.0071 | 0.0071 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0071 | 0.0199 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.268 | 0.5651 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.268 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.268 | 0.5651 |
Trichomonas vaginalis | type IV inositol 5-phosphatase, putative | 0.0004 | 0.0071 | 0.0199 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | synaptojanin | 0.0004 | 0.0071 | 0.0071 |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0004 | 0.0071 | 0.0265 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.268 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.268 | 1 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0956 | 0.2042 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.4688 | 1 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.268 | 0.268 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0651 | 0.1257 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.268 | 0.6023 |
Entamoeba histolytica | sphingomyelinase C precursor, putative | 0.0004 | 0.0071 | 0.0265 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.268 | 0.2966 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.268 | 1 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase domain containing protein | 0.0004 | 0.0071 | 0.0265 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.1916 |
Plasmodium falciparum | exodeoxyribonuclease III, putative | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | hypothetical protein | 0.0004 | 0.0071 | 0.0071 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.268 | 1 |
Entamoeba histolytica | inositol polyphosphate-5-phosphatase, putative | 0.0004 | 0.0071 | 0.0265 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4688 | 0.4688 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.268 | 0.6023 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0542 | 0.1969 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Entamoeba histolytica | inositol polyphosphate 5-phosphatase, putative | 0.0004 | 0.0071 | 0.0265 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.1969 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.4403 | 1 |
Trichomonas vaginalis | ocrl type II inositol 5-phosphatase, putative | 0.0004 | 0.0071 | 0.0199 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0004 | 0.0071 | 0.0265 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 0.1969 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.268 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.268 | 1 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.268 | 1 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.268 | 0.268 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.4403 | 1 |
Trichomonas vaginalis | sphingomyelinase C 2 precursor, putative | 0.0004 | 0.0071 | 0.0199 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.268 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.