Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.3615 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0128 | 0.4005 | 0.5 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0128 | 0.4005 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0128 | 0.3991 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0128 | 0.4005 | 1 |
Brugia malayi | TAR-binding protein | 0.0128 | 0.3991 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3615 | 0.9057 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0069 | 0.1037 | 0.2599 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.3991 | 0.9953 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0128 | 0.4005 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0128 | 0.4005 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0128 | 0.3991 | 0.995 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.3991 | 0.9953 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0128 | 0.3991 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0128 | 0.3991 | 0.9965 |
Echinococcus multilocularis | calpain A | 0.0073 | 0.1215 | 0.3035 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.3615 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3615 | 0.9057 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0128 | 0.4005 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.1037 | 0.2599 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0128 | 0.3991 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.1037 | 0.2599 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.3991 | 0.9953 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0073 | 0.1215 | 0.3035 |
Brugia malayi | hypothetical protein | 0.012 | 0.3615 | 0.8726 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0128 | 0.4005 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.3991 | 0.9953 |
Brugia malayi | RNA binding protein | 0.0128 | 0.3991 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0128 | 0.4005 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0073 | 0.1215 | 0.06 |
Loa Loa (eye worm) | RNA binding protein | 0.0128 | 0.3991 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0128 | 0.4005 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.3991 | 0.9953 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0073 | 0.1215 | 0.06 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.