Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0406 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.5383 | 0.723 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.1451 | 0.1451 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0406 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0406 | 0.5 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0232 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0406 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0406 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0132 | 0.5383 | 0.0897 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0165 | 0.6888 | 0.3865 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0406 | 0.5 |
Onchocerca volvulus | 0.0047 | 0.1451 | 0.5 | |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0406 | 0.5 |
Echinococcus multilocularis | geminin | 0.0165 | 0.6888 | 0.3865 |
Schistosoma mansoni | hypothetical protein | 0.0122 | 0.4928 | 0.6394 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0406 | 0.0406 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0406 | 0.5 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0232 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.5383 | 0.723 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.6888 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.6888 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.