TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 425.453 | Formula: C23H24FN3O4
H donors: 3 H acceptors: 3 LogP: 4.23 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: COc1c(NCCCc2ccccc2)c(F)c(c2c1n(cc(c2=O)C(=O)O)C1CC1)N
InChi: 1S/C23H24FN3O4/c1-31-22-19(26-11-5-8-13-6-3-2-4-7-13)17(24)18(25)16-20(22)27(14-9-10-14)12-15(21(16)28)23(29)30/h2-4,6-7,12,14,26H,5,8-11,25H2,1H3,(H,29,30)
InChiKey: SCUNYAMJRPWYRG-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	glycogen synthase kinase 3 beta	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Entamoeba histolytica	protein kinase domain containing protein	Get druggable targets OG5_126888	All targets in OG5_126888
Trichomonas vaginalis	CMGC family protein kinase	Get druggable targets OG5_126888	All targets in OG5_126888
Loa Loa (eye worm)	CMGC/GSK protein kinase	Get druggable targets OG5_126888	All targets in OG5_126888
Leishmania donovani	glycogen synthase kinase 3, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Plasmodium vivax	glycogen synthase kinase 3, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Theileria parva	glycogen synthase kinase, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Schistosoma japonicum	ko:K08822 glycogen synthase kinase 3 alpha, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Brugia malayi	intracellular kinase	Get druggable targets OG5_126888	All targets in OG5_126888
Trichomonas vaginalis	CMGC family protein kinase	Get druggable targets OG5_126888	All targets in OG5_126888
Leishmania mexicana	protein kinase, putative,glycogen synthase kinase, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Candida albicans	hypothetical protein	Get druggable targets OG5_126888	All targets in OG5_126888
Entamoeba histolytica	protein kinase domain containing protein	Get druggable targets OG5_126888	All targets in OG5_126888
Trypanosoma brucei	protein kinase, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Neospora caninum	hypothetical protein	Get druggable targets OG5_126888	All targets in OG5_126888
Loa Loa (eye worm)	CMGC/GSK protein kinase	Get druggable targets OG5_126888	All targets in OG5_126888
Cryptosporidium parvum	hypothetical protein	Get druggable targets OG5_126888	All targets in OG5_126888
Candida albicans	second truncated form of RIM11 Serine/threonine protein kinase	Get druggable targets OG5_126888	All targets in OG5_126888
Echinococcus granulosus	glycogen synthase kinase 3 beta	Get druggable targets OG5_126888	All targets in OG5_126888
Entamoeba histolytica	protein kinase, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Trypanosoma congolense	protein kinase, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Schistosoma mansoni	glycogen synthase kinase 3-related (gsk3) (cmgc group III)	Get druggable targets OG5_126888	All targets in OG5_126888
Trypanosoma cruzi	glycogen synthase kinase 3, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Plasmodium knowlesi	glycogen synthase kinase 3, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Toxoplasma gondii	cell-cycle-associated protein kinase GSK, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Echinococcus multilocularis	glycogen synthase kinase 3 beta	Get druggable targets OG5_126888	All targets in OG5_126888
Echinococcus multilocularis	protein kinase shaggy	Get druggable targets OG5_126888	All targets in OG5_126888
Plasmodium yoelii	Protein kinase domain, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Giardia lamblia	Kinase, CMGC GSK	Get druggable targets OG5_126888	All targets in OG5_126888
Plasmodium berghei	glycogen synthase kinase 3, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Trypanosoma brucei gambiense	protein kinase, putative,glycogen synthase kinase, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Echinococcus granulosus	protein kinase shaggy	Get druggable targets OG5_126888	All targets in OG5_126888
Candida albicans	Serine/threonine protein kinase required for induction of IME2 by Ime1p	Get druggable targets OG5_126888	All targets in OG5_126888
Plasmodium falciparum	glycogen synthase kinase 3	Get druggable targets OG5_126888	All targets in OG5_126888
Babesia bovis	protein kinase domain containing protein	Get druggable targets OG5_126888	All targets in OG5_126888
Leishmania infantum	glycogen synthase kinase 3	Get druggable targets OG5_126888	All targets in OG5_126888
Leishmania braziliensis	protein kinase, putative,glycogen synthase kinase, putative	Get druggable targets OG5_126888	All targets in OG5_126888
Leishmania major	glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270	Get druggable targets OG5_126888	All targets in OG5_126888
Cryptosporidium hominis	hypothetical protein	Get druggable targets OG5_126888	All targets in OG5_126888
Candida albicans	second truncated form of RIM11 Serine/threonine protein kinase	Get druggable targets OG5_126888	All targets in OG5_126888
Giardia lamblia	Kinase, CMGC GSK	Get druggable targets OG5_126888	All targets in OG5_126888
Onchocerca volvulus		Get druggable targets OG5_126888	All targets in OG5_126888

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Schistosoma mansoni	hypothetical protein	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 1, putative	0.0003	0.0021	0.0026
Echinococcus multilocularis	ubiquitin specific peptidase 42 (C19 family)	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 2, putative	0.0003	0.0021	0.0026
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 14	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Mycobacterium ulcerans	acyl-CoA synthetase	0.0021	0.2636	0.2636
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus multilocularis	Ubiquitin carboxyl terminal hydrolase 48	0.0003	0.0021	0.0026
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0026
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 36	0.0003	0.0021	0.0026
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Plasmodium falciparum	acyl-CoA synthetase	0.0054	0.7364	0.9293
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 7	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Treponema pallidum	long-chain-fatty-acid--CoA ligase	0.0003	0	0.5
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase family 2 protein	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 12	0.0003	0.0021	0.0026
Brugia malayi	Low-density lipoprotein receptor domain class A containing protein	0.0005	0.0299	0.0299
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma brucei	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Mycobacterium ulcerans	acyl-CoA synthetase	0.0021	0.2636	0.2636
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Plasmodium vivax	hypothetical protein, conserved	0.0003	0.0021	0.0026
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0021	0.2636	0.2636
Brugia malayi	Low-density lipoprotein receptor domain class A containing protein	0.0005	0.0299	0.0299
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 36	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0054	0.7364	0.7364
Loa Loa (eye worm)	low-density lipoprotein receptor domain class A containing protein	0.0005	0.0299	0.0299
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Schistosoma mansoni	family C19 non-peptidase homologue (C19 family)	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Plasmodium vivax	acetyl-CoA synthetase, putative	0.0021	0.2636	0.3326
Onchocerca volvulus	Terribly reduced optic lobes homolog	0.0005	0.0299	0.0299
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0021
Mycobacterium ulcerans	long-chain-acyl-CoA synthetase	0.0021	0.2636	0.2636
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.6518	0.8225
Onchocerca volvulus		0.0003	0.0021	0.0021
Schistosoma mansoni	ubiquitin-specific peptidase 9X (C19 family)	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 7	0.0003	0.0021	0.0026
Onchocerca volvulus		0.0021	0.2636	0.2636
Loa Loa (eye worm)	hypothetical protein	0.0054	0.7364	0.7364
Trichomonas vaginalis	antibiotic synthetase, putative	0.0021	0.2636	0.3326
Schistosoma mansoni	family C19 unassigned peptidase (C19 family)	0.0003	0.0021	0.0026
Leishmania major	ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Onchocerca volvulus		0.0021	0.2636	0.2636
Echinococcus multilocularis	acetyl coenzyme A synthetase, cytoplasmic	0.0021	0.2636	0.3326
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0003	0.0021	0.0026
Schistosoma mansoni	hypothetical protein	0.0005	0.0299	0.0377
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Onchocerca volvulus		0.0021	0.2636	0.2636
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 4	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	antibiotic synthetase, putative	0.0021	0.2636	0.3326
Trypanosoma cruzi	acetyl-CoA synthetase, putative	0.0021	0.2636	0.3326
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0051	0.6939	0.6939
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Brugia malayi	acetyl-Coenzyme A synthetase 2	0.0021	0.2636	0.2636
Echinococcus granulosus	Peptidase C19 ubiquitin carboxyl terminal hydrolase 2	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Toxoplasma gondii	hypothetical protein	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Schistosoma mansoni	ubiquitin-specific peptidase 9X (C19 family)	0.0003	0.0021	0.0026
Brugia malayi	CUB domain containing protein	0.0005	0.0299	0.0299
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0072	1	1
Brugia malayi	Low-density lipoprotein receptor domain class A containing protein	0.0005	0.0299	0.0299
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0026
Plasmodium falciparum	U4/U6.U5 tri-snRNP-associated protein 2, putative	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0072	1	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0072	1	1
Echinococcus granulosus	5'partial\|Low density lipoprotein receptor class A cysteine rich	0.0005	0.0299	0.0377
Giardia lamblia	DUB-1	0.0003	0.0021	0.0026
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Onchocerca volvulus	Arrow homolog	0.0005	0.0299	0.0299
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.6518	0.8225
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Mycobacterium ulcerans	acyl-CoA synthetase	0.0021	0.2636	0.2636
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus granulosus	glycogen synthase kinase 3 beta	0.0058	0.7925	1
Echinococcus multilocularis	low density lipoprotein receptor (ldl)	0.0005	0.0299	0.0377
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0026
Onchocerca volvulus		0.0005	0.0299	0.0299
Trypanosoma brucei	long-chain-fatty-acid-CoA ligase, putative	0.0021	0.2636	0.3326
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Mycobacterium ulcerans	O-succinylbenzoic acid--CoA ligase	0.0021	0.2636	0.2636
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Trypanosoma cruzi	long-chain-fatty-acid-CoA ligase, putative	0.0021	0.2636	0.3326
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0021
Mycobacterium ulcerans	acyl-CoA synthetase	0.0072	1	1
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0003	0.0021	0.0026
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Mycobacterium ulcerans	acyl-CoA synthetase	0.0072	1	1
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Echinococcus granulosus	low density lipoprotein receptor ldl	0.0005	0.0299	0.0377
Giardia lamblia	Kinase, CMGC GSK	0.0058	0.7925	1
Plasmodium vivax	acyl-CoA synthetase, putative	0.0054	0.7364	0.9293
Echinococcus granulosus	basement membrane specific heparan sulfate	0.0005	0.0299	0.0377
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Toxoplasma gondii	cell-cycle-associated protein kinase GSK, putative	0.0058	0.7925	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Mycobacterium ulcerans	bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase	0.0021	0.2636	0.2636
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0054	0.7364	0.7364
Mycobacterium ulcerans	acyl-CoA synthetase	0.0021	0.2636	0.2636
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Mycobacterium tuberculosis	P-hydroxybenzoyl-AMP ligase FadD22	0.0021	0.2636	0.2636
Mycobacterium tuberculosis	Probable peptide synthetase Nrp (peptide synthase)	0.0021	0.2636	0.2636
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 4	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Loa Loa (eye worm)	low-density lipoprotein receptor domain class A containing protein	0.0005	0.0299	0.0299
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Schistosoma mansoni	ubiquitin-specific peptidase 42 (C19 family)	0.0003	0.0021	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Mycobacterium leprae	Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase)	0.0021	0.2636	0.2636
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Onchocerca volvulus		0.0005	0.0299	0.0299
Loa Loa (eye worm)	hypothetical protein	0.0072	1	1
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 8	0.0003	0.0021	0.0026
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Mycobacterium ulcerans	peptide synthetase Nrp (peptide synthase)	0.0021	0.2636	0.2636
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase family 2, putative	0.0003	0.0021	0.0026
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Echinococcus multilocularis	Low density lipoprotein receptor, class A, cysteine rich	0.0005	0.0299	0.0377
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase	0.0003	0.0021	0.0026
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0021
Loa Loa (eye worm)	calcium binding EGF domain-containing protein	0.0005	0.0299	0.0299
Onchocerca volvulus		0.0005	0.0299	0.0299
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Brugia malayi	Low-density lipoprotein receptor-related protein, putative	0.0005	0.0299	0.0299
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Onchocerca volvulus		0.0005	0.0299	0.0299
Mycobacterium tuberculosis	Peptide synthetase MbtE (peptide synthase)	0.0021	0.2636	0.2636
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0003	0.0021	0.0026
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Echinococcus multilocularis	ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Schistosoma mansoni	ubiquitin-specific peptidase 14 (C19 family)	0.0003	0.0021	0.0026
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0051	0.6939	0.6939
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Schistosoma mansoni	ubiquitin-specific peptidase 4 (C19 family)	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0054	0.7364	0.7364
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Schistosoma mansoni	ubiquitin-specific peptidase 2 (C19 family)	0.0003	0.0021	0.0026
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 22	0.0003	0.0021	0.0026
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 2, putative	0.0003	0.0021	0.0026
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0072	1	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.6518	0.8225
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma brucei	protein kinase, putative	0.0058	0.7925	1
Schistosoma mansoni	ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold	0.0003	0.0021	0.0026
Onchocerca volvulus		0.0003	0.0021	0.0021
Mycobacterium leprae	POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE)	0.0021	0.2636	0.2636
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0021
Echinococcus multilocularis	low density lipoprotein receptor protein	0.0005	0.0299	0.0377
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase 5, putative	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Schistosoma mansoni	peptidase	0.0004	0.0101	0.0127
Brugia malayi	hypothetical protein	0.0003	0.0021	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0072	1	1
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0026
Mycobacterium ulcerans	acetyl-CoA synthetase	0.0021	0.2636	0.2636
Loa Loa (eye worm)	ubiquitin specific peptidase 39	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0003	0.0021	0.0026
Toxoplasma gondii	Acetyl-coenzyme A synthetase 2, putative	0.0021	0.2636	0.3326
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0072	1	1
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Mycobacterium ulcerans	acyl-CoA synthetase	0.0021	0.2636	0.2636
Entamoeba histolytica	protein kinase domain containing protein	0.0058	0.7925	0.7925
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus multilocularis	protein kinase shaggy	0.0058	0.7925	1
Leishmania major	4-coumarate:coa ligase-like protein	0.0072	1	1
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Brugia malayi	Low-density lipoprotein receptor domain class A containing protein	0.0005	0.0299	0.0299
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0005	0.0299	0.0377
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Brugia malayi	basement membrane proteoglycan precursor	0.0005	0.0299	0.0299
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 16	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 14	0.0003	0.0021	0.0026
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0021	0.2636	0.2636
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0048	0.6518	0.6518
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0026
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0021
Mycobacterium ulcerans	non-ribosomal peptide synthetase MbtE	0.0021	0.2636	0.2636
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 24	0.0003	0.0021	0.0026
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus multilocularis	Low density lipoprotein receptor, class A, cysteine rich	0.0005	0.0299	0.0377
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0054	0.7364	0.5
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0054	0.7364	0.7364
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Mycobacterium ulcerans	hypothetical protein	0.0072	1	1
Toxoplasma gondii	ubiquitin-specific protease USP4	0.0003	0.0021	0.0026
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 13, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Leishmania major	long-chain-fatty-acid-CoA ligase, putative	0.0021	0.2636	0.2636
Loa Loa (eye worm)	hypothetical protein	0.0021	0.2636	0.2636
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Plasmodium vivax	U4/U6.U5 tri-snRNP-associated protein 2, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 8	0.0003	0.0021	0.0026
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0005	0.0299	0.0377
Entamoeba histolytica	hypothetical protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0003	0.0021	0.0026
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Mycobacterium ulcerans	acyl-CoA synthetase	0.0021	0.2636	0.2636
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Schistosoma mansoni	ubiquitin-specific peptidase 5 (C19 family)	0.0003	0.0021	0.0026
Brugia malayi	enteropeptidase precursor	0.0005	0.0299	0.0299
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 47	0.0003	0.0021	0.0026
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Leishmania major	glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270	0.0058	0.7925	0.7925
Brugia malayi	AMP-binding enzyme family protein	0.0021	0.2636	0.2636
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Entamoeba histolytica	long-chain-fatty-acid--CoA ligase, putative	0.0021	0.2636	0.2636
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Plasmodium falciparum	glycogen synthase kinase 3	0.0058	0.7925	1
Leishmania major	acetyl-CoA synthetase, putative	0.0021	0.2636	0.2636
Echinococcus multilocularis	low density lipoprotein receptor (ldl)	0.0005	0.0299	0.0377
Giardia lamblia	Kinase, CMGC GSK	0.0058	0.7925	1
Onchocerca volvulus		0.0005	0.0299	0.0299
Schistosoma mansoni	hypothetical protein	0.0005	0.0299	0.0377
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 23	0.0003	0.0021	0.0026
Echinococcus granulosus	u4:u6.u5 tri snrnp associated protein 2	0.0003	0.0021	0.0026
Echinococcus granulosus	low density lipoprotein receptor ldl	0.0005	0.0299	0.0377
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0005	0.0299	0.0377
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus multilocularis	Peptidase C19, ubiquitin carboxyl terminal hydrolase 2	0.0003	0.0021	0.0026
Plasmodium vivax	ubiquitin specific protease, putative	0.0003	0.0021	0.0026
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Trypanosoma cruzi	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 20	0.0003	0.0021	0.0026
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 14	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Plasmodium falciparum	acetyl-CoA synthetase, putative	0.0021	0.2636	0.3326
Trichomonas vaginalis	CMGC family protein kinase	0.0058	0.7925	1
Mycobacterium tuberculosis	Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase)	0.0021	0.2636	0.2636
Entamoeba histolytica	protein kinase, putative	0.0058	0.7925	0.7925
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Schistosoma mansoni	ubiquitin-specific peptidase 24 (C19 family)	0.0003	0.0021	0.0026
Toxoplasma gondii	UBA/TS-N domain-containing protein	0.0003	0.0021	0.0026
Echinococcus multilocularis	expressed protein	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0003	0.0021	0.0026
Plasmodium vivax	glycogen synthase kinase 3, putative	0.0058	0.7925	1
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 16	0.0003	0.0021	0.0026
Echinococcus granulosus	Low density lipoprotein receptor class A cysteine rich	0.0005	0.0299	0.0377
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase 46	0.0003	0.0021	0.0021
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Plasmodium falciparum	ubiquitin specific protease, putative	0.0003	0.0021	0.0026
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0072	1	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Plasmodium falciparum	ubiquitin specific protease, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Mycobacterium ulcerans	acyl-CoA synthetase	0.0072	1	1
Loa Loa (eye worm)	hypothetical protein	0.0021	0.2636	0.2636
Schistosoma mansoni	low-density lipoprotein receptor (ldl)	0.0005	0.0299	0.0377
Mycobacterium tuberculosis	PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0018	0.221	0.221
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0051	0.6939	0.6939
Echinococcus granulosus	5'partial\|Ubiquitin carboxyl terminal hydrolase 48	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Mycobacterium ulcerans	non-ribosomal peptide synthetase MbtF	0.0021	0.2636	0.2636
Brugia malayi	intracellular kinase	0.0058	0.7925	0.7925
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 14	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0058	0.7925	0.7925
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0048	0.6518	0.8225
Brugia malayi	Calcium binding EGF domain containing protein	0.0005	0.0299	0.0299
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0026
Schistosoma mansoni	ubiquitin-specific peptidase 10 (C19 family)	0.0003	0.0021	0.0026
Schistosoma mansoni	ubiquitin-specific peptidase 22 (C19 family)	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Brugia malayi	AMP-binding enzyme family protein	0.0021	0.2636	0.2636
Trypanosoma brucei	cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0026
Loa Loa (eye worm)	AMP-binding enzyme family protein	0.0021	0.2636	0.2636
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0048	0.6518	0.6518
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 7	0.0003	0.0021	0.0026
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 7	0.0003	0.0021	0.0026
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Echinococcus granulosus	acetyl coenzyme A synthetase cytoplasmic	0.0021	0.2636	0.3326
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Mycobacterium tuberculosis	Peptide synthetase MbtF (peptide synthase)	0.0021	0.2636	0.2636
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 12	0.0003	0.0021	0.0026
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0072	1	1
Schistosoma mansoni	ubiquitin-specific peptidase 44 (C19 family)	0.0003	0.0021	0.0026
Trichomonas vaginalis	CMGC family protein kinase	0.0058	0.7925	1
Echinococcus multilocularis	ubiquitin specific protease 41	0.0003	0.0021	0.0026
Brugia malayi	AMP-binding enzyme family protein	0.0021	0.2636	0.2636
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0051	0.6939	0.6939
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma cruzi	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Echinococcus granulosus	ubiquitin specific peptidase 30 (C19 family)	0.0003	0.0021	0.0026
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 5	0.0003	0.0021	0.0026
Schistosoma mansoni	ubiquitin-specific peptidase 30 (C19 family)	0.0003	0.0021	0.0026
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0054	0.7364	0.7364
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Schistosoma mansoni	ubiquitin-specific peptidase 8 (C19 family)	0.0003	0.0021	0.0026
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0072	1	1
Giardia lamblia	Hypothetical protein	0.0003	0.0021	0.0026
Mycobacterium tuberculosis	Phenyloxazoline synthase MbtB (phenyloxazoline synthetase)	0.0021	0.2636	0.2636
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 24	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0003	0.0021	0.0026
Schistosoma mansoni	acetyl-CoA synthetase	0.0021	0.2636	0.3326
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Echinococcus granulosus	ubiquitin specific protease 41	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0072	1	1
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Loa Loa (eye worm)	low-density lipoprotein receptor repeat class B containing protein	0.0005	0.0299	0.0299
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Onchocerca volvulus		0.0005	0.0299	0.0299
Schistosoma mansoni	ubiquitin-specific peptidase 16 (C19 family)	0.0003	0.0021	0.0026
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 22	0.0003	0.0021	0.0026
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Echinococcus granulosus	ubiquitin specific peptidase c family	0.0003	0.0021	0.0026
Onchocerca volvulus		0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Brugia malayi	Low-density lipoprotein receptor repeat class B containing protein	0.0005	0.0299	0.0299
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0003	0.0021	0.0026
Schistosoma mansoni	calpain-7 (C02 family)	0.0003	0.0021	0.0026
Onchocerca volvulus	Basement membrane proteoglycan homolog	0.0005	0.0299	0.0299
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0048	0.6518	0.8225
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Toxoplasma gondii	propionate-CoA ligase	0.0021	0.2636	0.3326
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Onchocerca volvulus		0.0058	0.7925	0.7925
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0054	0.7364	0.7364
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0072	1	1
Schistosoma mansoni	calpain-7 (C02 family)	0.0003	0.0021	0.0026
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0072	1	1
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0003	0.0021	0.0026
Brugia malayi	AMP-binding enzyme family protein	0.0021	0.2636	0.2636
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trypanosoma cruzi	acetyl-CoA synthetase, putative	0.0021	0.2636	0.3326
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Mycobacterium leprae	POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0021	0.2636	0.2636
Trypanosoma brucei	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0003	0.0021	0.0026
Trypanosoma brucei	acetyl-CoA synthetase, putative	0.0021	0.2636	0.3326
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Brugia malayi	ubiquitin carboxyl-terminal hydrolase 46	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Schistosoma mansoni	low-density lipoprotein receptor (ldl)	0.0005	0.0299	0.0377
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 13, putative	0.0003	0.0021	0.0026
Brugia malayi	AMP-binding enzyme family protein	0.0072	1	1
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0048	0.6518	0.8225
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0021
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Echinococcus granulosus	Ubiquitin carboxyl terminal hydrolase 48	0.0003	0.0021	0.0026
Leishmania major	4-coumarate:coa ligase-like protein	0.0072	1	1
Schistosoma mansoni	glycogen synthase kinase 3-related (gsk3) (cmgc group III)	0.0058	0.7925	1
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0026
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Trypanosoma cruzi	glycogen synthase kinase 3, putative	0.0058	0.7925	1
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Brugia malayi	Low-density lipoprotein receptor domain class A containing protein	0.0005	0.0299	0.0299
Toxoplasma gondii	ubiquitin specific protease 39 isoform 2, putative	0.0003	0.0021	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Mycobacterium ulcerans	acyl-CoA synthetase	0.0021	0.2636	0.2636
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0003	0.0021	0.0026
Schistosoma mansoni	ubiquitin-specific peptidase 45 (C19 family)	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Brugia malayi	ubiquitin specific protease 14	0.0003	0.0021	0.0021
Loa Loa (eye worm)	AMP-binding enzyme family protein	0.0021	0.2636	0.2636
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Toxoplasma gondii	AMP-binding enzyme domain-containing protein	0.0021	0.2636	0.3326
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus multilocularis	Low density lipoprotein receptor, class A, cysteine rich	0.0005	0.0299	0.0377
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0048	0.6518	0.8225
Mycobacterium tuberculosis	Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase	0.0021	0.2636	0.2636
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0026
Brugia malayi	AMP-binding enzyme family protein	0.0072	1	1
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase 5, putative	0.0003	0.0021	0.0021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0021	0.2636	0.2636
Mycobacterium tuberculosis	Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0021	0.2636	0.2636
Leishmania major	acetyl-CoA synthetase, putative	0.0021	0.2636	0.2636
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0003	0.0021	0.0021
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 20	0.0003	0.0021	0.0026
Echinococcus granulosus	basement membrane specific heparan sulfate	0.0005	0.0299	0.0377
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Mycobacterium ulcerans	phenyloxazoline synthase MbtB	0.0021	0.2636	0.2636
Mycobacterium tuberculosis	Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0021	0.2636	0.2636
Schistosoma mansoni	ubiquitin-specific peptidase 46 (C19 family)	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0058	0.7925	0.7925
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 47	0.0003	0.0021	0.0026
Trypanosoma cruzi	long-chain-fatty-acid-CoA ligase, putative	0.0021	0.2636	0.3326
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0003	0.0021	0.0021
Leishmania major	4-coumarate:coa ligase-like protein	0.0072	1	1
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0021
Entamoeba histolytica	protein kinase domain containing protein	0.0058	0.7925	0.7925
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0003	0.0021	0.0021
Onchocerca volvulus		0.0021	0.2636	0.2636
Trichomonas vaginalis	conserved hypothetical protein	0.0003	0.0021	0.0026
Echinococcus multilocularis	u4:u6.u5 tri snrnp associated protein 2	0.0003	0.0021	0.0026
Loa Loa (eye worm)	low-density lipoprotein receptor domain class A containing protein	0.0005	0.0299	0.0299
Onchocerca volvulus		0.0072	1	1
Schistosoma mansoni	low-density lipoprotein receptor (ldl)	0.0005	0.0299	0.0377
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Schistosoma mansoni	ubiquitin-specific peptidase 7 (C19 family)	0.0003	0.0021	0.0026
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 5	0.0003	0.0021	0.0026
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Mycobacterium tuberculosis	Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0021	0.2636	0.2636
Entamoeba histolytica	acyl-coA synthetase, putative	0.0072	1	1
Brugia malayi	Low-density lipoprotein receptor domain class A containing protein	0.0005	0.0299	0.0299
Echinococcus granulosus	low density lipoprotein receptor protein	0.0005	0.0299	0.0377
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0003	0.0021	0.0026
Echinococcus multilocularis	glycogen synthase kinase 3 beta	0.0058	0.7925	1
Brugia malayi	Low-density lipoprotein receptor domain class A containing protein	0.0005	0.0299	0.0299
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0026
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 14	0.0003	0.0021	0.0026
Mycobacterium ulcerans	acyl-CoA synthetase	0.0021	0.2636	0.2636
Schistosoma mansoni	ubiquitin-specific peptidase 48 (C19 family)	0.0003	0.0021	0.0026
Echinococcus granulosus	protein kinase shaggy	0.0058	0.7925	1
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0003	0.0021	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0299	0.0299
Loa Loa (eye worm)	oxidoreductase	0.0021	0.2636	0.2636

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 65 nM	Inhibition of human recombinant full length GSK3-beta after 1 hrs by luminescence assay	ChEMBL.	21873061

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1834123

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1150562