Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | macrophage migration inhibitory factor | 0.0368 | 1 | 1 |
Toxoplasma gondii | macrophage migration inhibitory factor, putative | 0.0368 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0368 | 1 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0187 | 0.3171 | 1 |
Trichomonas vaginalis | macrophage migration inhibitory factor, mif, putative | 0.0368 | 1 | 0.5 |
Plasmodium falciparum | macrophage migration inhibitory factor | 0.0368 | 1 | 0.5 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0368 | 1 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0187 | 0.3171 | 1 |
Entamoeba histolytica | macrophage migration inhibitory factor-like protein | 0.0368 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.2422 | 0.7639 |
Plasmodium vivax | macrophage migration inhibitory factor, putative | 0.0368 | 1 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.015 | 0.1792 | 0.1792 |
Schistosoma mansoni | tar DNA-binding protein | 0.0187 | 0.3171 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0187 | 0.3171 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0187 | 0.3171 | 0.3171 |
Schistosoma mansoni | tar DNA-binding protein | 0.0187 | 0.3171 | 1 |
Brugia malayi | TAR-binding protein | 0.0187 | 0.3171 | 0.3171 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0177 | 0.281 | 0.281 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0368 | 1 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.015 | 0.1792 | 0.1792 |
Giardia lamblia | Macrophage migration inhibitory factor | 0.0368 | 1 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0187 | 0.3171 | 0.3171 |
Brugia malayi | RNA binding protein | 0.0187 | 0.3171 | 0.3171 |
Echinococcus multilocularis | tar DNA binding protein | 0.0187 | 0.3171 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.1792 | 0.1792 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.015 | 0.1792 | 0.1792 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0187 | 0.3171 | 0.3171 |
Loa Loa (eye worm) | RNA binding protein | 0.0187 | 0.3171 | 0.3171 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.2422 | 0.7639 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0177 | 0.281 | 0.281 |
Echinococcus granulosus | tar DNA binding protein | 0.0187 | 0.3171 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.