Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0152 | 1 | 1 |
Leishmania major | 0.0152 | 1 | 1 | |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0152 | 1 | 1 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0152 | 1 | 1 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0152 | 1 | 1 |
Entamoeba histolytica | cdc48-like protein, putative | 0.0028 | 0.1238 | 0.5 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0152 | 1 | 1 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0057 | 0.3239 | 0.2283 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.0057 | 0.3239 | 0.2883 |
Toxoplasma gondii | cell division protein CDC48AP | 0.0018 | 0.0499 | 0.00000087414 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0152 | 1 | 1 |
Toxoplasma gondii | fructose-bisphospatase I | 0.0057 | 0.3239 | 0.2883 |
Mycobacterium ulcerans | ATPase | 0.0018 | 0.0499 | 0.5 |
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.0057 | 0.3239 | 0.2283 |
Brugia malayi | vesicle-fusing ATPase | 0.0017 | 0.0474 | 0.0369 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.003 | 0.1347 | 0.1252 |
Entamoeba histolytica | transitional endoplasmic reticulum ATPase, putative | 0.0028 | 0.1238 | 0.5 |
Mycobacterium tuberculosis | Putative conserved ATPase | 0.0018 | 0.0499 | 0.5 |
Toxoplasma gondii | cell division protein CDC48CY | 0.003 | 0.1347 | 0.0892 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0152 | 1 | 1 |
Trichomonas vaginalis | spermatogenesis associated factor, putative | 0.003 | 0.1347 | 0.5 |
Giardia lamblia | AAA family ATPase | 0.0018 | 0.0499 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0474 | 0.0369 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.003 | 0.1347 | 0.1252 |
Onchocerca volvulus | Transitional endoplasmic reticulum ATPase homolog | 0.003 | 0.1347 | 0.5 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0028 | 0.1238 | 0.1142 |
Plasmodium falciparum | cell division cycle protein 48 homologue, putative | 0.0028 | 0.1238 | 0.5 |
Brugia malayi | valosin containing protein | 0.0017 | 0.0474 | 0.0369 |
Loa Loa (eye worm) | vesicle-fusing ATPase | 0.0017 | 0.0474 | 0.0369 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0057 | 0.3239 | 0.2283 |
Plasmodium vivax | cell division cycle protein 48 homologue, putative | 0.0028 | 0.1238 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.