Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | geminin | 0.0164 | 0.1188 | 0.1188 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0056 | 0.0115 | 0.0115 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0162 | 0.117 | 0.117 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.117 | 0.117 |
Loa Loa (eye worm) | aminopeptidase N | 0.0056 | 0.0115 | 0.0115 |
Brugia malayi | Peptidase family M1 containing protein | 0.0056 | 0.0115 | 0.0265 |
Toxoplasma gondii | hypothetical protein | 0.0162 | 0.117 | 1 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0056 | 0.0115 | 0.0115 |
Brugia malayi | jmjC domain containing protein | 0.0092 | 0.0478 | 0.1095 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0162 | 0.117 | 0.2684 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0056 | 0.0115 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0162 | 0.117 | 0.117 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0345 | 0.2987 | 0.2987 |
Onchocerca volvulus | 0.0056 | 0.0115 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0056 | 0.0115 | 0.0265 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.1051 | 1 | 1 |
Schistosoma mansoni | carbonic anhydrase | 0.0162 | 0.117 | 0.117 |
Brugia malayi | TATA binding protein associated factor | 0.0056 | 0.0115 | 0.0265 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0162 | 0.117 | 0.2684 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0056 | 0.0115 | 0.0115 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0162 | 0.117 | 0.117 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0056 | 0.0115 | 0.0115 |
Onchocerca volvulus | 0.0056 | 0.0115 | 0.5 | |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0056 | 0.0115 | 0.0115 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0056 | 0.0115 | 0.0115 |
Brugia malayi | Peptidase family M1 containing protein | 0.0056 | 0.0115 | 0.0265 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0162 | 0.117 | 0.117 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.117 | 0.117 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0667 | 0.6186 | 0.6186 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0345 | 0.2987 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0162 | 0.117 | 0.117 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0345 | 0.2987 | 0.2987 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0056 | 0.0115 | 0.0115 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0056 | 0.0115 | 0.0115 |
Echinococcus multilocularis | aminopeptidase N | 0.0056 | 0.0115 | 0.0115 |
Echinococcus granulosus | carbonic anhydrase | 0.0162 | 0.117 | 0.117 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0056 | 0.0115 | 0.0115 |
Echinococcus multilocularis | carbonic anhydrase | 0.0162 | 0.117 | 0.117 |
Echinococcus granulosus | carbonic anhydrase II | 0.0345 | 0.2987 | 0.2987 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0162 | 0.117 | 0.2684 |
Echinococcus multilocularis | carbonic anhydrase | 0.0162 | 0.117 | 0.117 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0162 | 0.117 | 0.2684 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0667 | 0.6186 | 0.6186 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0345 | 0.2987 | 0.2987 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.117 | 0.117 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0092 | 0.0478 | 0.0478 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0115 | 0.0115 |
Entamoeba histolytica | aminopeptidase, putative | 0.0056 | 0.0115 | 0.5 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0056 | 0.0115 | 0.0115 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0056 | 0.0115 | 0.0115 |
Brugia malayi | hypothetical protein | 0.0056 | 0.0115 | 0.0265 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0345 | 0.2987 | 1 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0345 | 0.2987 | 0.685 |
Plasmodium falciparum | carbonic anhydrase | 0.0162 | 0.117 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0115 | 0.0115 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.1188 | 0.1188 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0345 | 0.2987 | 0.2987 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.1051 | 1 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0056 | 0.0115 | 0.0115 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0056 | 0.0115 | 0.5 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0056 | 0.0115 | 0.0115 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0056 | 0.0115 | 0.0115 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0056 | 0.0115 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0056 | 0.0115 | 0.0115 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0162 | 0.117 | 0.2684 |
Leishmania major | carbonic anhydrase-like protein | 0.0345 | 0.2987 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0162 | 0.117 | 0.117 |
Brugia malayi | hypothetical protein | 0.0483 | 0.436 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0056 | 0.0115 | 0.0115 |
Echinococcus granulosus | geminin | 0.0164 | 0.1188 | 0.1188 |
Onchocerca volvulus | 0.0056 | 0.0115 | 0.5 | |
Echinococcus granulosus | carbonic anhydrase | 0.0162 | 0.117 | 0.117 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.1188 | 0.1188 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0056 | 0.0115 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0056 | 0.0115 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0115 | 0.0115 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0667 | 0.6186 | 0.6186 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0056 | 0.0115 | 0.5 |
Schistosoma mansoni | jumonji domain containing protein | 0.0073 | 0.0289 | 0.0289 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0056 | 0.0115 | 0.0115 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.1051 | 1 | 1 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0056 | 0.0115 | 0.5 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0345 | 0.2987 | 0.685 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0345 | 0.2987 | 0.2987 |
Brugia malayi | Peptidase family M1 containing protein | 0.0056 | 0.0115 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0041 | 0.0041 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0092 | 0.0478 | 0.0478 |
Echinococcus multilocularis | carbonic anhydrase | 0.0162 | 0.117 | 0.117 |
Echinococcus granulosus | aminopeptidase N | 0.0056 | 0.0115 | 0.0115 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0056 | 0.0115 | 0.5 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0345 | 0.2987 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.