Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | neuroligin | 0.0052 | 0.1162 | 0.1162 |
Echinococcus granulosus | acetylcholinesterase | 0.0307 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0307 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0307 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0307 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0307 | 1 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0052 | 0.1162 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1162 | 0.1162 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1047 | 0.1047 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0052 | 0.1162 | 0.1162 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.1162 | 0.1162 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0307 | 1 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0 | 0.5 |
Echinococcus multilocularis | neuroligin | 0.0052 | 0.1162 | 0.1162 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0052 | 0.1162 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0052 | 0.1162 | 0.1162 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0052 | 0.1162 | 0.1162 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0052 | 0.1162 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0307 | 1 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0 | 0.5 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.4404 | 0.4404 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0515 | 0.0515 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1162 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.4404 | 0.4404 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0515 | 0.0515 |
Onchocerca volvulus | 0.0052 | 0.1162 | 0.5 | |
Onchocerca volvulus | 0.0052 | 0.1162 | 0.5 | |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0052 | 0.1162 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.1162 | 0.1162 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1047 | 0.1047 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0307 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0052 | 0.1162 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1162 | 0.1162 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.1162 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1162 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0307 | 1 | 1 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1047 | 0.1047 |
Schistosoma mansoni | gliotactin | 0.0052 | 0.1162 | 0.1162 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0052 | 0.1162 | 0.1162 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0052 | 0.1162 | 0.1162 |
Onchocerca volvulus | 0.0052 | 0.1162 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.0307 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0307 | 1 | 1 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1162 | 0.1162 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.4404 | 0.4404 |
Echinococcus multilocularis | acetylcholinesterase | 0.0307 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.4404 | 0.4404 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1047 | 0.1047 |
Onchocerca volvulus | 0.0052 | 0.1162 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0052 | 0.1162 | 0.1162 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.4404 | 0.4404 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0515 | 0.0515 |
Loa Loa (eye worm) | carboxylesterase | 0.0052 | 0.1162 | 0.1162 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0052 | 0.1162 | 0.1162 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0052 | 0.1162 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0052 | 0.1162 | 0.1162 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0052 | 0.1162 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1162 | 0.1162 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.1162 | 0.1162 |
Onchocerca volvulus | 0.0052 | 0.1162 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0052 | 0.1162 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1162 | 0.1162 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.4404 | 0.4404 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0052 | 0.1162 | 0.1162 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0052 | 0.1162 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0052 | 0.1162 | 0.1162 |
Schistosoma mansoni | acetylcholinesterase | 0.0052 | 0.1162 | 0.1162 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.