Detailed information for compound 1152236

Basic information

Technical information
  • TDR Targets ID: 1152236
  • Name: 5,6,7,8-Tetramethoxy-1,2,3,4-tetrahydroisoqui noline
  • MW: 253.294 | Formula: C13H19NO4
  • H donors: 1 H acceptors: 0 LogP: 1.21 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1c(OC)c(OC)c2c(c1OC)CNCC2
  • InChi: 1S/C13H19NO4/c1-15-10-8-5-6-14-7-9(8)11(16-2)13(18-4)12(10)17-3/h14H,5-7H2,1-4H3
  • InChiKey: OPCOVGPGIKKXAT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • Isoquinoline, 1,2,3,4-tetrahydro-5,6,7,8-tetramethoxy-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major hypothetical protein, conserved 0.0237 0.0943 0.3137
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0057 0.0124 0.0388
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0057 0.0124 0.0143
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0244 0.0976 0.0976
Loa Loa (eye worm) DR-78 0.004 0.0045 0.0066
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0122 0.018
Onchocerca volvulus Bile acid receptor homolog 0.0084 0.0246 0.028
Trichomonas vaginalis CAMK family protein kinase 0.0687 0.2989 0.3878
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0159 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0032 0.0033
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0043 0.0159
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.0023 0.0023
Trypanosoma brucei heat shock protein, putative 0.0098 0.0312 0.1045
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.004 0.0045 0.0045
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0623 0.2698 0.3498
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0043 0.0116
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0008 0.0006
Brugia malayi nuclear hormone receptor 0.0084 0.0246 0.0365
Brugia malayi CHE-14 protein 0.0048 0.0081 0.0121
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0057 0.0124 0.0395
Loa Loa (eye worm) hypothetical protein 0.0085 0.0249 0.037
Schistosoma mansoni disulfide oxidoreductase 0.0057 0.0124 0.0124
Brugia malayi ecdysone receptor 0.004 0.0045 0.0066
Echinococcus multilocularis isocitrate dehydrogenase 0.0049 0.0089 0.0089
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0046 0.0073 0.0272
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0225 0.0284
Entamoeba histolytica heat shock protein 90, putative 0.0098 0.0312 0.1026
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0057 0.0124 0.0153
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0078 0.0221 0.0715
Echinococcus multilocularis Smad4 0.005 0.0092 0.0092
Brugia malayi MH1 domain containing protein 0.005 0.0092 0.0136
Schistosoma mansoni smad1 5 8 and 0.005 0.0092 0.0092
Echinococcus multilocularis cpg binding protein 0.0095 0.0296 0.0296
Echinococcus multilocularis lamin 0.0056 0.0122 0.0122
Leishmania major NADH dehydrogenase, putative 0.0057 0.0124 0.0388
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0057 0.0124 0.0462
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0081 0.0235 0.0235
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0122 0.018
Schistosoma mansoni jumonji domain containing protein 0.1061 0.469 0.469
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0124 0.0388
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0006 0.0023
Schistosoma mansoni rab6-interacting 0.0085 0.0249 0.0249
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0035 0.0025 0.0025
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0084 0.0246 0.0365
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0235 0.0297
Trichomonas vaginalis heat shock protein, putative 0.0098 0.0312 0.0398
Schistosoma mansoni coup transcription factor 0.0084 0.0246 0.0246
Brugia malayi hypothetical protein 0.004 0.0045 0.0066
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0215 0.0841 0.3136
Schistosoma mansoni kinase 0.0349 0.1453 0.1453
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0047
Trichomonas vaginalis endoplasmin, putative 0.006 0.0139 0.0173
Toxoplasma gondii heat shock protein HSP90 0.0098 0.0312 0.1165
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0623 0.2698 0.3498
Trichomonas vaginalis CAMK family protein kinase 0.0687 0.2989 0.3878
Loa Loa (eye worm) Smad1 0.005 0.0092 0.0136
Trichomonas vaginalis heat shock protein, putative 0.006 0.0139 0.0173
Trypanosoma brucei Heat shock protein 83, putative 0.0098 0.0312 0.1045
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0089 0.0298
Mycobacterium tuberculosis Probable dehydrogenase 0.1413 0.6289 0.8973
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0225 0.0288
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0044 0.0066 0.0066
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0215 0.0841 0.3136
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0098
Brugia malayi latrophilin 2 splice variant baaae 0.0075 0.0206 0.0305
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0084 0.0246 0.0365
Brugia malayi intermediate filament protein 0.0056 0.0122 0.018
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0113 0.0377 0.0377
Trypanosoma brucei heat shock protein 90, putative 0.0098 0.0312 0.1045
Plasmodium vivax ferrodoxin reductase, putative 0.0057 0.0124 0.0462
Plasmodium falciparum heat shock protein 90 0.0098 0.0312 0.1165
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Loa Loa (eye worm) transcription factor SMAD2 0.0732 0.3194 0.4732
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0388 0.0496
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0084 0.0246 0.0246
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0506 0.2166 0.3068
Echinococcus granulosus chromobox protein 2 0.0037 0.0032 0.0032
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0043 0.0122
Brugia malayi Steroid receptor seven-up type 2 0.0084 0.0246 0.0365
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0057 0.0124 0.0143
Trypanosoma cruzi trypanothione reductase, putative 0.0215 0.0841 0.2793
Loa Loa (eye worm) jmjC domain-containing protein 0.0237 0.0943 0.1397
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0238 0.0947 0.0947
Onchocerca volvulus 0.0084 0.0246 0.028
Brugia malayi Hsp90 protein 0.004 0.0048 0.0072
Giardia lamblia Fructose-bisphosphate aldolase 0.0623 0.2698 0.9022
Loa Loa (eye worm) pip kinase 2 0.017 0.0636 0.0942
Plasmodium vivax endoplasmin, putative 0.0098 0.0312 0.1165
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0084 0.0246 0.0365
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0057 0.0124 0.0644
Onchocerca volvulus 0.0099 0.0313 0.0366
Plasmodium falciparum heterochromatin protein 1 0.0037 0.0032 0.0118
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.1413 0.6289 0.8973
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0225 0.0288
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.004 0.0048 0.0022
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0174 0.0174
Echinococcus granulosus thyroid hormone receptor alpha 0.004 0.0045 0.0045
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.1413 0.6289 0.8973
Loa Loa (eye worm) hypothetical protein 0.0079 0.0225 0.0333
Brugia malayi conserved hypotetical protein 0.004 0.0045 0.0066
Plasmodium vivax heat shock protein 90, putative 0.004 0.0048 0.018
Brugia malayi AF-10 protein 0.004 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.017 0.0636 0.0942
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0184 0.0184
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0623 0.2698 0.3498
Brugia malayi Associated with TFs and helicases family protein 0.0037 0.0032 0.0047
Giardia lamblia Heat shock protein HSP 90-alpha 0.0078 0.0221 0.0721
Loa Loa (eye worm) hypothetical protein 0.011 0.0364 0.0539
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0057 0.0124 0.0388
Echinococcus granulosus Chromobox protein 3 0.0037 0.0032 0.0032
Echinococcus granulosus geminin 0.0547 0.2354 0.2354
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0057 0.0124 0.0153
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0057 0.0124 0.0184
Entamoeba histolytica hypothetical protein 0.0037 0.0032 0.0085
Brugia malayi hypothetical protein 0.004 0.0045 0.0066
Brugia malayi Bromodomain containing protein 0.0126 0.0439 0.065
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0225 0.0284
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0081 0.0235 0.0235
Mycobacterium tuberculosis Conserved protein 0.0079 0.0225 0.0288
Brugia malayi Valyl-tRNA synthetase 0.0037 0.0032 0.0047
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0012 0.0007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0623 0.2698 0.3498
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.0023 0.0034
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0098
Entamoeba histolytica 90 kDa heat shock protein, putative 0.004 0.0048 0.0141
Brugia malayi phosphofructokinase 0.0115 0.0388 0.0575
Toxoplasma gondii aldehyde dehydrogenase 0.0317 0.1304 0.4864
Loa Loa (eye worm) steroid hormone receptor 0.0084 0.0246 0.0365
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0057 0.0124 0.0153
Brugia malayi mbt repeat family protein 0.0195 0.0752 0.1115
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0265 0.0393
Loa Loa (eye worm) hypothetical protein 0.0084 0.0246 0.0365
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0215 0.0841 0.2793
Schistosoma mansoni hypothetical protein 0.0547 0.2354 0.2354
Brugia malayi nuclear receptor RXR 0.0044 0.0066 0.0098
Schistosoma mansoni aldehyde dehydrogenase 0.0317 0.1304 0.1304
Brugia malayi heat shock protein 90 0.0098 0.0312 0.0463
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0124 0.0388
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.004 0.0045 0.0045
Plasmodium falciparum LCCL domain-containing protein 0.0085 0.0249 0.0931
Echinococcus granulosus cpg binding protein 0.0095 0.0296 0.0296
Echinococcus multilocularis heat shock protein 90 0.0078 0.0221 0.0221
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0237 0.0943 0.3137
Loa Loa (eye worm) hypothetical protein 0.0055 0.0117 0.0173
Echinococcus multilocularis expressed protein 0.0032 0.0012 0.0012
Echinococcus multilocularis Polycystic kidney disease protein 0.0085 0.0249 0.0249
Onchocerca volvulus 0.0932 0.4101 0.5307
Brugia malayi nuclear hormone receptor family member odr-7 0.004 0.0045 0.0066
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0057 0.0124 0.0143
Loa Loa (eye worm) histone methyltransferase 0.0035 0.0025 0.0037
Brugia malayi MH1 domain containing protein 0.005 0.0092 0.0136
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Giardia lamblia Kinase, PLK 0.0687 0.2989 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0122 0.018
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0126 0.0436 0.0527
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0215 0.0841 0.0841
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0225 0.0333
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0215 0.0841 0.6327
Schistosoma mansoni nuclear receptor 0.004 0.0045 0.0045
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0045 0.0017
Onchocerca volvulus 0.0233 0.0922 0.1161
Loa Loa (eye worm) thioredoxin reductase 0.062 0.2681 0.3972
Toxoplasma gondii phosphomannose isomerase type I protein 0.0099 0.0314 0.1173
Trypanosoma brucei trypanothione reductase 0.062 0.2681 0.8969
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1571 0.7005 1
Echinococcus granulosus RUN 0.0085 0.0249 0.0249
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0032 0.0085
Schistosoma mansoni lamin 0.0056 0.0122 0.0122
Echinococcus multilocularis JmjC domain containing protein 4 0.0237 0.0943 0.0943
Trichomonas vaginalis chromobox protein, putative 0.0224 0.0884 0.1141
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0065 0.0159 0.0159
Echinococcus granulosus snurportin 1 0.0317 0.1307 0.1307
Echinococcus granulosus FTZ F1 alpha 0.0084 0.0246 0.0246
Echinococcus multilocularis lipoxygenase domain containing protein 0.0085 0.0249 0.0249
Trichomonas vaginalis CAMK family protein kinase 0.034 0.1412 0.1827
Schistosoma mansoni nuclear hormone receptor 0.004 0.0045 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0269 0.0342
Brugia malayi Isocitrate dehydrogenase 0.0049 0.0089 0.0132
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.004 0.0048 0.0048
Giardia lamblia NADH oxidase lateral transfer candidate 0.0215 0.0841 0.2798
Mycobacterium ulcerans ferredoxin reductase 0.0057 0.0124 0.0644
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0084 0.0246 0.0246
Echinococcus granulosus lipoxygenase domain containing protein 0.0085 0.0249 0.0249
Brugia malayi Smad1 0.005 0.0092 0.0136
Loa Loa (eye worm) jmjC domain-containing protein 0.0897 0.3941 0.5839
Echinococcus granulosus tar DNA binding protein 0.0068 0.0174 0.0174
Brugia malayi MH2 domain containing protein 0.005 0.0092 0.0136
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.017 0.0636 0.0636
Echinococcus granulosus Niemann Pick C1 protein 0.0159 0.0586 0.0586
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0215 0.0841 0.2813
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0057 0.0124 0.0153
Entamoeba histolytica hypothetical protein 0.0116 0.0392 0.1295
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0238 0.0947 0.0947
Echinococcus multilocularis expressed conserved protein 0.0104 0.0339 0.0339
Trypanosoma brucei heat shock protein, putative 0.0098 0.0312 0.1045
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0436 0.0559
Plasmodium vivax hypothetical protein, conserved 0.0124 0.0427 0.1591
Brugia malayi Nuclear hormone receptor E75 0.004 0.0045 0.0066
Schistosoma mansoni sex comb on midleg homolog 0.0195 0.0752 0.0752
Brugia malayi Pre-SET motif family protein 0.0219 0.086 0.1274
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0244 0.0976 0.0976
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0122 0.0151
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0256 0.1027 0.1027
Onchocerca volvulus 0.0079 0.0225 0.0252
Trypanosoma cruzi Heat shock protein 83, putative 0.0098 0.0312 0.102
Loa Loa (eye worm) hypothetical protein 0.0046 0.0074 0.0109
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0225 0.0728
Echinococcus multilocularis smad 0.005 0.0092 0.0092
Echinococcus granulosus nuclear receptor nhr 48 0.004 0.0045 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0081 0.0098
Loa Loa (eye worm) glutathione reductase 0.062 0.2681 0.3972
Schistosoma mansoni nuclear receptor 0.004 0.0045 0.0045
Plasmodium vivax thioredoxin reductase, putative 0.062 0.2681 1
Loa Loa (eye worm) PHD-finger family protein 0.0124 0.0427 0.0632
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0081 0.0235 0.0766
Entamoeba histolytica heat shock protein 90, putative 0.0098 0.0312 0.1026
Schistosoma mansoni inositol monophosphatase 0.0039 0.0043 0.0043
Trichomonas vaginalis chromobox protein, putative 0.0037 0.0032 0.0033
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0084 0.0246 0.0246
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0057 0.0124 0.0124
Trichomonas vaginalis set domain proteins, putative 0.1724 0.7699 1
Plasmodium falciparum mannose-6-phosphate isomerase, putative 0.0099 0.0314 0.1173
Loa Loa (eye worm) heat shock protein 90 0.0098 0.0312 0.0463
Schistosoma mansoni bromodomain containing protein 0.0076 0.0212 0.0212
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0317 0.1304 0.4347
Trypanosoma cruzi NADH dehydrogenase, putative 0.0057 0.0124 0.0388
Brugia malayi hypothetical protein 0.0932 0.4101 0.6076
Loa Loa (eye worm) hypothetical protein 0.0084 0.0246 0.0365
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0057 0.0124 0.0124
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0057 0.0124 0.0644
Schistosoma mansoni hypothetical protein 0.0057 0.0124 0.0124
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0057 0.0124 0.0644
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0174 0.0258
Mycobacterium ulcerans dehydrogenase 0.0057 0.0124 0.0644
Entamoeba histolytica hypothetical protein 0.0037 0.0032 0.0085
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0047
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0057 0.0124 0.0395
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0084 0.0246 0.0365
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.0159 0.0193
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0237 0.0942 0.0942
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.0023 0.0023
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0317 0.1307 0.1936
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.004 0.0048 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0032 0.0033
Entamoeba histolytica mannose-6-phosphate isomerase, putative 0.0045 0.0071 0.0216
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0066 0.0098
Loa Loa (eye worm) nuclear hormone receptor 0.004 0.0045 0.0066
Schistosoma mansoni polycystin 1-related 0.0085 0.0249 0.0249
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0037 0.0032 0.0032
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0037 0.0032 0.0118
Plasmodium vivax heat shock protein, putative 0.004 0.0048 0.018
Loa Loa (eye worm) nuclear receptor nhr-7B 0.004 0.0045 0.0066
Trichomonas vaginalis chromobox protein, putative 0.0037 0.0032 0.0033
Echinococcus multilocularis FTZ F1 alpha 0.0084 0.0246 0.0246
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0008 0.0027
Leishmania major heat shock protein, putative 0.004 0.0048 0.0135
Brugia malayi CHD4 protein 0.0044 0.0064 0.0095
Trypanosoma cruzi trypanothione reductase, putative 0.062 0.2681 0.8966
Schistosoma mansoni sex comb on midleg homolog 0.0195 0.0752 0.0752
Echinococcus granulosus TGF beta signal transducer SmadC 0.005 0.0092 0.0092
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0687 0.2989 0.2989
Entamoeba histolytica serine/threonine protein kinase, putative 0.0687 0.2989 1
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0089 0.0332
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0032 0.0118
Brugia malayi M-phase phosphoprotein, mpp8 0.0037 0.0032 0.0047
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0081 0.0081
Onchocerca volvulus Alhambra homolog 0.0124 0.0427 0.0515
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0084 0.0246 0.0246
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0388 0.2738
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1571 0.7005 1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0081 0.0235 0.0235
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0159 0.0921
Loa Loa (eye worm) pax transcription factor protein 2 0.0233 0.0922 0.1366
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Onchocerca volvulus 0.0088 0.0264 0.0303
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0215 0.0841 0.2813
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.0012 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0388 0.0496
Onchocerca volvulus 0.0195 0.0752 0.094
Echinococcus granulosus mannose 6 phosphate isomerase 0.0099 0.0314 0.0314
Echinococcus multilocularis lamin dm0 0.0056 0.0122 0.0122
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0049 0.0089 0.0089
Trypanosoma cruzi phosphomannose isomerase, putative 0.0099 0.0314 0.1027
Schistosoma mansoni phd/f-box containing protein 0.0237 0.0943 0.0943
Onchocerca volvulus 0.0088 0.0265 0.0304
Loa Loa (eye worm) helicase 0.0037 0.0032 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0032 0.0118
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0037 0.0032 0.0118
Mycobacterium ulcerans heat shock protein 90 0.0078 0.0221 0.1416
Loa Loa (eye worm) beta-lactamase 0.0079 0.0225 0.0333
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0084 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0035 0.0023 0.0034
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0317 0.1304 0.1304
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0388 0.0388
Onchocerca volvulus 0.0079 0.0225 0.0252
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0122 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0084 0.0246 0.0365
Trypanosoma cruzi NADH dehydrogenase, putative 0.0057 0.0124 0.0388
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Schistosoma mansoni nuclear hormone receptor 0.0084 0.0246 0.0246
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Loa Loa (eye worm) hypothetical protein 0.0043 0.0062 0.0091
Schistosoma mansoni smad1 5 8 and 0.005 0.0092 0.0092
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0225 0.1446
Treponema pallidum fructose-bisphosphate aldolase 0.0623 0.2698 1
Brugia malayi mbt repeat family protein 0.0195 0.0752 0.1115
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0049 0.0089 0.0332
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0043 0.0047
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Echinococcus granulosus fetal alzheimer antigen falz 0.003 0.0003 0.0003
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0049 0.0089 0.0298
Brugia malayi Bromodomain containing protein 0.009 0.0272 0.0403
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.004 0.0048 0.0162
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0084 0.0246 0.0365
Toxoplasma gondii NADPH-glutathione reductase 0.0215 0.0841 0.3136
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0215 0.0841 0.2793
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0388 0.128
Brugia malayi Pip kinase protein 2 0.017 0.0636 0.0942
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0057 0.0124 0.0153
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0081 0.0121
Giardia lamblia Thioredoxin reductase 0.0057 0.0124 0.0395
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0047
Echinococcus granulosus PHD finger protein rhinoceros 0.0124 0.0427 0.0427
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0265 0.0265
Echinococcus multilocularis SAM and MBT domain containing protein 0.0195 0.0752 0.0752
Giardia lamblia Grp94/Hsp90 0.0078 0.0221 0.0721
Echinococcus multilocularis polycomb protein SCMH1 0.0195 0.0752 0.0752
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0057 0.0124 0.0644
Mycobacterium ulcerans NADH dehydrogenase 0.0057 0.0124 0.0644
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0081 0.0081
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0194 0.0748 0.0748
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0174 0.0174
Entamoeba histolytica hypothetical protein 0.0116 0.0392 0.1295
Schistosoma mansoni hypothetical protein 0.0046 0.0074 0.0074
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0044 0.0044
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0057 0.0124 0.0124
Mycobacterium ulcerans hypothetical protein 0.0079 0.0225 0.1446
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0049 0.0089 0.0089
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.003 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0032 0.0033
Schistosoma mansoni chromobox protein 0.0037 0.0032 0.0032
Schistosoma mansoni nuclear receptor nhr-48 0.004 0.0045 0.0045
Schistosoma mansoni lipoxygenase 0.0237 0.0942 0.0942
Loa Loa (eye worm) hypothetical protein 0.0085 0.0249 0.037
Brugia malayi beta-lactamase family protein 0.0079 0.0225 0.0333
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0388 0.1419
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0037 0.0032 0.0032
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0215 0.0841 0.6327
Brugia malayi PHD-finger family protein 0.0048 0.0081 0.012
Trypanosoma brucei heat shock protein, putative 0.0098 0.0312 0.1045
Brugia malayi serine/threonine-protein kinase plk-2 0.0687 0.2989 0.4429
Brugia malayi RNA binding protein 0.0068 0.0174 0.0258
Mycobacterium tuberculosis Probable oxidoreductase 0.1571 0.7005 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0084 0.0246 0.0365
Onchocerca volvulus 0.0079 0.0225 0.0252
Onchocerca volvulus 0.0056 0.0122 0.0117
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0006 0.0023
Toxoplasma gondii PHD-finger domain-containing protein 0.0124 0.0427 0.1591
Schistosoma mansoni sulfide quinone reductase 0.0057 0.0124 0.0124
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0081 0.0235 0.0235
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0121 0.0415 0.0615
Echinococcus granulosus Chromo domain 0.0037 0.0032 0.0032
Echinococcus multilocularis endoplasmin 0.0078 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0079 0.0225 0.0333
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0057 0.0124 0.0388
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.0159 0.0505
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Onchocerca volvulus Serine\/threonine kinase homolog 0.0687 0.2989 0.3857
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0225 0.0728
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Brugia malayi SET domain containing protein 0.0047 0.0077 0.0114
Echinococcus granulosus Polycystic kidney disease protein 0.0085 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0932 0.4101 0.6076
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0215 0.0841 0.2793
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0057 0.0124 0.0388
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0215 0.0841 0.6327
Trypanosoma cruzi heat shock protein, putative 0.004 0.0048 0.0135
Loa Loa (eye worm) hypothetical protein 0.008 0.0227 0.0337
Echinococcus multilocularis phd:f box containing protein 0.0237 0.0943 0.0943
Plasmodium falciparum endoplasmin, putative 0.006 0.0139 0.052
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0032 0.0033
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0099 0.0314 0.0466
Schistosoma mansoni TGF-beta signal transducer Smad2 0.005 0.0092 0.0092
Loa Loa (eye worm) MH1 domain-containing protein 0.005 0.0092 0.0136
Schistosoma mansoni intermediate filament proteins 0.0056 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0237 0.0943 0.1397
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0084 0.0246 0.0365
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0219 0.086 0.3207
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0084 0.0246 0.0365
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0057 0.0124 0.0415
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0057 0.0124 0.0415
Schistosoma mansoni endoplasmin 0.0098 0.0312 0.0312
Trypanosoma cruzi polo-like protein kinase, putative 0.0687 0.2989 1
Echinococcus granulosus jumonji domain containing 1A 0.0237 0.0943 0.0943
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0158 0.0582 0.0862
Schistosoma mansoni lipoxygenase 0.0085 0.0249 0.0249
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0089 0.0089
Loa Loa (eye worm) CXXC zinc finger family protein 0.0088 0.0264 0.0391
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.004 0.0048 0.0181
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0057 0.0124 0.0415
Loa Loa (eye worm) hypothetical protein 0.0084 0.0246 0.0365
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0043 0.0116
Entamoeba histolytica hypothetical protein 0.0037 0.0032 0.0085
Onchocerca volvulus 0.1724 0.7699 1
Toxoplasma gondii heat shock protein 90, putative 0.0098 0.0312 0.1165
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0081 0.0235 0.0235
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0057 0.0124 0.0462
Trichomonas vaginalis CAMK family protein kinase 0.0687 0.2989 0.3878
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0122 0.0151
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0235 0.076
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0098
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0057 0.0124 0.0415
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0043 0.0116
Trichomonas vaginalis Heterochromatin protein, putative 0.0037 0.0032 0.0033
Echinococcus multilocularis PHD finger protein rhinoceros 0.0124 0.0427 0.0427
Loa Loa (eye worm) heat shock protein 75 0.004 0.0048 0.0072
Echinococcus multilocularis chromobox protein 1 0.0224 0.0884 0.0884
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0235 0.076
Loa Loa (eye worm) hypothetical protein 0.0099 0.0313 0.0463
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0037 0.0032 0.0032
Trypanosoma cruzi heat shock protein 85, putative 0.0078 0.0221 0.0715
Loa Loa (eye worm) endoplasmin 0.0098 0.0312 0.0463
Loa Loa (eye worm) hypothetical protein 0.0084 0.0246 0.0365
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0057 0.0124 0.0462
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0044 0.0064 0.0064
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0073 0.0272
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Echinococcus multilocularis ecdysone induced protein 78C 0.0084 0.0246 0.0246
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0225 0.0225
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0687 0.2989 0.2989
Schistosoma mansoni nuclear hormone receptor 0.004 0.0045 0.0045
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0122 0.0151
Trichomonas vaginalis heat shock protein, putative 0.0078 0.0221 0.0279
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0215 0.0841 0.117
Trichomonas vaginalis chromobox protein, putative 0.0037 0.0032 0.0033
Brugia malayi Bromodomain containing protein 0.0043 0.0061 0.0091
Brugia malayi Endoplasmin precursor 0.0098 0.0312 0.0463
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.017 0.0636 0.0636
Echinococcus granulosus Smad4 0.005 0.0092 0.0092
Echinococcus multilocularis ubiquitin specific protease 41 0.0081 0.0235 0.0235
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0045 0.0045
Brugia malayi nuclear receptor RXR 0.004 0.0045 0.0066
Trypanosoma brucei heat shock protein, putative 0.0098 0.0312 0.1045
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0006 0.0023
Schistosoma mansoni RAR-like nuclear receptor 0.0084 0.0246 0.0246
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0078 0.0221 0.2237
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0084 0.0246 0.0365
Brugia malayi CXXC zinc finger family protein 0.0088 0.0264 0.0391
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0215 0.0841 0.2793
Loa Loa (eye worm) hypothetical protein 0.0084 0.0246 0.0365
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0032 0.0085
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0225 0.0288
Schistosoma mansoni hypothetical protein 0.0035 0.0023 0.0023
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0044 0.0066 0.0066
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0057 0.0124 0.0395
Trichomonas vaginalis mercuric reductase, putative 0.0215 0.0841 0.1085
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0089 0.0332
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0304 0.1249 0.1754
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0084 0.0246 0.0365
Schistosoma mansoni phosphatidylserine receptor 0.0237 0.0943 0.0943
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0057 0.0124 0.1018
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0043 0.0047
Brugia malayi TAR-binding protein 0.0068 0.0174 0.0258
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0225 0.0225
Trichomonas vaginalis chromobox protein, putative 0.0135 0.0479 0.0615
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0057 0.0124 0.0644
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0312 0.102
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0037 0.0032 0.0032
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0215 0.0841 0.2813
Schistosoma mansoni chromobox protein 0.0037 0.0032 0.0032
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0057 0.0124 0.0644
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0006 0.0023
Echinococcus granulosus intermediate filament protein 0.0056 0.0122 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0084 0.0246 0.0365
Loa Loa (eye worm) hypothetical protein 0.0222 0.0875 0.1297
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0045 0.0045
Brugia malayi chromobox protein homolog 3 0.0126 0.0436 0.0646
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0388 0.1274
Leishmania major hypothetical protein, conserved 0.0057 0.0124 0.0388
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0122 0.0151
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0043 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0235 0.0297
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0084 0.0246 0.0246
Plasmodium vivax glutathione reductase, putative 0.062 0.2681 1
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0099 0.0314 0.0466
Echinococcus multilocularis mannose 6 phosphate isomerase 0.0099 0.0314 0.0314
Loa Loa (eye worm) MH2 domain-containing protein 0.0732 0.3194 0.4732
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0388 0.0388
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0237 0.0943 0.3155
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0047
Echinococcus multilocularis chromobox protein 1 0.0224 0.0884 0.0884
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0219 0.086 0.086
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0215 0.0841 0.2793
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0057 0.0124 0.0124
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0049 0.0049
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0057 0.0124 0.0184
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0174 0.0557
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0006 0.0023
Schistosoma mansoni jumonji/arid domain-containing protein 0.0897 0.3941 0.3941
Brugia malayi tailless protein 0.004 0.0045 0.0066
Echinococcus granulosus lysine specific demethylase 6a 0.0237 0.0943 0.0943
Echinococcus granulosus smad 0.005 0.0092 0.0092
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0215 0.0841 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0388 0.0575
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0074 0.0088
Schistosoma mansoni hypothetical protein 0.0116 0.0392 0.0392
Schistosoma mansoni rotamase 0.0032 0.0012 0.0012
Onchocerca volvulus 0.0256 0.1027 0.1298
Trichomonas vaginalis CAMK family protein kinase 0.034 0.1412 0.1827
Echinococcus multilocularis Niemann Pick C1 protein 0.0111 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.0057 0.0124 0.0184
Schistosoma mansoni lamin 0.0056 0.0122 0.0122
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.004 0.0048 0.0162
Brugia malayi nuclear receptor NHR-88 0.004 0.0045 0.0066
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0237 0.0942 0.0942
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0032 0.0033
Mycobacterium tuberculosis Conserved protein 0.0079 0.0225 0.0288
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0215 0.0841 0.0841
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0098
Toxoplasma gondii Hsp90 domain-containing protein 0.004 0.0048 0.018
Schistosoma mansoni hypothetical protein 0.0075 0.0206 0.0206
Trichomonas vaginalis esterase, putative 0.0079 0.0225 0.0284
Mycobacterium ulcerans aldehyde dehydrogenase 0.0317 0.1304 1
Trichomonas vaginalis glutathione reductase, putative 0.0215 0.0841 0.1085
Loa Loa (eye worm) hypothetical protein 0.0121 0.0415 0.0615
Schistosoma mansoni loxhd1 0.0085 0.0249 0.0249
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0122 0.0151
Echinococcus multilocularis geminin 0.0547 0.2354 0.2354
Trypanosoma brucei heat shock protein 84, putative 0.004 0.0048 0.0161
Brugia malayi jmjC domain containing protein 0.0237 0.0943 0.1397
Echinococcus multilocularis lipoxygenase domain containing protein 0.0085 0.0249 0.0249
Brugia malayi Thioredoxin reductase 0.062 0.2681 0.3972
Echinococcus multilocularis thyroid hormone receptor alpha 0.0084 0.0246 0.0246
Entamoeba histolytica hypothetical protein 0.0116 0.0392 0.1295
Echinococcus multilocularis histone acetyltransferase MYST2 0.0222 0.0875 0.0875
Mycobacterium ulcerans glutamate synthase subunit beta 0.0057 0.0124 0.0644
Echinococcus granulosus lamin dm0 0.0056 0.0122 0.0122
Brugia malayi nuclear receptor NHR-67 0.004 0.0045 0.0066
Echinococcus multilocularis mothers against decapentaplegic 5 0.005 0.0092 0.0092
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0225 0.0284
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1515 0.6749 1
Leishmania major hypothetical protein, conserved 0.0079 0.0225 0.0728
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0269 0.0342
Mycobacterium ulcerans monoxygenase 0.0057 0.0124 0.0644
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0215 0.0841 0.3136
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0159 0.0235
Echinococcus multilocularis Protein lozenge 0.0117 0.0396 0.0396
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0215 0.0841 0.2793
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0057 0.0124 0.0143
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.0012 0.0017
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0116 0.0392 0.0392
Echinococcus granulosus glutamate synthase 0.0057 0.0124 0.0124
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0081 0.0235 0.076
Loa Loa (eye worm) inositol-1 0.0039 0.0043 0.0063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0122 0.0151
Brugia malayi beta-lactamase 0.0079 0.0225 0.0333
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0388 0.128
Echinococcus multilocularis fetal alzheimer antigen, falz 0.003 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0195 0.0752 0.1115
Echinococcus multilocularis heat shock protein 0.0098 0.0312 0.0312
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho 0.0054 0.0109 0.0121
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0215 0.0841 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0057 0.0124 0.0388
Plasmodium falciparum JmjC domain-containing protein, putative 0.0237 0.0943 0.3518
Onchocerca volvulus 0.004 0.0045 0.0017
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0081 0.0235 0.0235
Schistosoma mansoni cpg binding protein 0.0088 0.0264 0.0264
Brugia malayi 6-phosphofructokinase 0.0115 0.0388 0.0575
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.004 0.0045 0.0045
Echinococcus multilocularis thioredoxin glutathione reductase 0.0623 0.2698 0.2698
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0057 0.0124 0.0124
Plasmodium vivax multidomain scavenger receptor, putative 0.0085 0.0249 0.0931
Echinococcus granulosus ubiquitin specific protease 41 0.0081 0.0235 0.0235
Treponema pallidum heat shock protein 90 0.0078 0.0221 0.0799
Echinococcus multilocularis microtubule associated protein 2 0.223 1 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.0225 0.0333
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0049 0.0089 0.0332
Trichomonas vaginalis rotamase, putative 0.0032 0.0008 0.0002
Toxoplasma gondii thioredoxin reductase 0.062 0.2681 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0045 0.0045
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Echinococcus granulosus SAM and MBT domain containing protein 0.0195 0.0752 0.0752
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0687 0.2989 1
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0008 0.003
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0057 0.0124 0.0124
Schistosoma mansoni retinoic acid receptor RXR 0.0084 0.0246 0.0246
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.0023 0.0034
Trypanosoma cruzi phosphomannose isomerase, putative 0.0099 0.0314 0.1027
Echinococcus multilocularis nuclear receptor nhr 48 0.004 0.0045 0.0045
Mycobacterium ulcerans hypothetical protein 0.0057 0.0124 0.0644
Toxoplasma gondii ABC1 family protein 0.0079 0.0225 0.084
Schistosoma mansoni hypothetical protein 0.0046 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0238 0.0947 0.1403
Echinococcus granulosus GPCR family 2 0.0035 0.0023 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0084 0.0246 0.0365
Schistosoma mansoni mannose-6-phosphate isomerase 0.0099 0.0314 0.0314
Plasmodium falciparum glutathione reductase 0.062 0.2681 1
Echinococcus multilocularis Chromobox protein 3 0.0037 0.0032 0.0032
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0235 0.0786
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.004 0.0045 0.0045
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0388 0.0521
Trichomonas vaginalis apoptosis inducing factor, putative 0.0057 0.0124 0.0153
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0057 0.0124 0.0143
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0089 0.0271
Treponema pallidum NADH oxidase 0.0215 0.0841 0.3101
Loa Loa (eye worm) hypothetical protein 0.0079 0.0225 0.0333
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Mycobacterium tuberculosis Conserved protein 0.0079 0.0225 0.0288
Loa Loa (eye worm) doublecortin family protein 0.0085 0.0249 0.037
Echinococcus multilocularis protein patched 0.0048 0.0081 0.0081
Schistosoma mansoni hypothetical protein 0.1191 0.5279 0.5279
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0215 0.0841 0.3136
Brugia malayi ecdysteroid receptor 0.0084 0.0246 0.0365
Loa Loa (eye worm) jmjC domain-containing protein 0.0237 0.0943 0.1397
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0043 0.0043
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0057 0.0124 0.0395
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.004 0.0045 0.0045
Loa Loa (eye worm) RNA binding protein 0.0068 0.0174 0.0258
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0057 0.0124 0.0395
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0037 0.0032 0.0118
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0222 0.0875 0.0875
Echinococcus multilocularis heat shock protein 90 0.0098 0.0312 0.0312
Trypanosoma cruzi polo-like protein kinase, putative 0.0687 0.2989 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0047
Brugia malayi Heterochromatin protein 1 0.0224 0.0884 0.131
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0057 0.0124 0.0143
Loa Loa (eye worm) hypothetical protein 0.0084 0.0246 0.0365
Echinococcus granulosus mothers against decapentaplegic 5 0.005 0.0092 0.0092
Brugia malayi Doublecortin family protein 0.0085 0.0249 0.037
Echinococcus multilocularis chromobox protein 2 0.0037 0.0032 0.0032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0317 0.1304 1
Plasmodium falciparum heat shock protein 90, putative 0.004 0.0048 0.018
Echinococcus granulosus jumonji domain containing protein 0.0172 0.0646 0.0646
Schistosoma mansoni smad 0.005 0.0092 0.0092
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.008 0.0096
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0174 0.0174
Loa Loa (eye worm) isocitrate dehydrogenase 0.0049 0.0089 0.0132
Schistosoma mansoni cpg binding protein 0.0095 0.0296 0.0296
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0158 0.0582 0.0862
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0159 0.0159
Trypanosoma brucei heat shock protein 90, putative 0.0098 0.0312 0.1045
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0057 0.0124 0.0153
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0388 0.128
Mycobacterium leprae Probable lipase LipE 0.0079 0.0225 0.0288
Brugia malayi PHD-finger family protein 0.0124 0.0427 0.0632
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0057 0.0124 0.0462
Schistosoma mansoni hypothetical protein 0.0035 0.0023 0.0023
Trypanosoma brucei hypothetical protein, conserved 0.0057 0.0124 0.0415
Schistosoma mansoni heat shock protein 0.0098 0.0312 0.0312
Brugia malayi glutathione reductase 0.062 0.2681 0.3972
Schistosoma mansoni hypothetical protein 0.0035 0.0023 0.0023
Brugia malayi Calcitonin receptor-like protein seb-1 0.011 0.0364 0.0539
Loa Loa (eye worm) hypothetical protein 0.0084 0.0246 0.0365
Loa Loa (eye worm) runx1 0.0117 0.0396 0.0587
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0045 0.0017
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0174 0.0557
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0044 0.0064 0.0064
Echinococcus multilocularis lysine specific demethylase 6a 0.0237 0.0943 0.0943
Toxoplasma gondii PHD-finger domain-containing protein 0.0124 0.0427 0.1591
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0623 0.2698 0.3498
Schistosoma mansoni serine/threonine protein kinase 0.0687 0.2989 0.2989
Onchocerca volvulus 0.0056 0.0122 0.0117
Schistosoma mansoni hypothetical protein 0.0547 0.2354 0.2354
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0057 0.0124 0.0153
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0089 0.0089
Echinococcus multilocularis peregrin 0.0126 0.0439 0.0439
Brugia malayi Nuclear hormone receptor E75 0.004 0.0045 0.0066
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0215 0.0841 1
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0057 0.0124 0.0124
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0388 0.0496
Loa Loa (eye worm) hypothetical protein 0.0409 0.1725 0.2555
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0174 0.0557
Toxoplasma gondii histone lysine methyltransferase SET1 0.0177 0.0669 0.2496
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0265 0.0265
Loa Loa (eye worm) hypothetical protein 0.0111 0.0369 0.0547
Schistosoma mansoni inositol monophosphatase 0.0039 0.0043 0.0043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0032 0.0033
Echinococcus granulosus expressed conserved protein 0.0104 0.0339 0.0339
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0174 0.0583
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0084 0.0246 0.028
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0126 0.0436 0.0646
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0057 0.0124 0.1018
Trichomonas vaginalis mannose-6-phosphate isomerase, putative 0.0099 0.0314 0.0401
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0057 0.0124 0.1018
Echinococcus granulosus histone lysine methyltransferase setb 0.0238 0.0947 0.0947
Onchocerca volvulus 0.0037 0.0032 0.000000053874
Trichomonas vaginalis heat shock protein, putative 0.004 0.0048 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0084 0.0246 0.0365
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0045 0.0045
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0066 0.0066
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0225 0.0284
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0174 0.0174
Schistosoma mansoni patched 1 0.0048 0.0081 0.0081
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0215 0.0841 0.2813
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0225 0.0753
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0081 0.0235 0.0766
Trypanosoma brucei heat shock protein, putative 0.0098 0.0312 0.1045
Brugia malayi MH2 domain containing protein 0.005 0.0092 0.0136
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0078 0.0221 0.0282
Plasmodium falciparum glutathione reductase 0.0215 0.0841 0.3136
Giardia lamblia PHD finger protein 15 0.0124 0.0427 0.1409
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0174 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0032 0.0033
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0174 0.0258
Trichomonas vaginalis CAMK family protein kinase 0.0687 0.2989 0.3878
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0116 0.0392 0.0392
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0215 0.0841 0.0841
Brugia malayi Latrophilin receptor protein 2 0.0035 0.0023 0.0034
Mycobacterium tuberculosis Probable reductase 0.1413 0.6289 0.8973
Brugia malayi steroid hormone receptor 0.0084 0.0246 0.0365
Plasmodium vivax JmjC domain containing protein 0.0237 0.0943 0.3518
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0174 0.0258
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0174 0.0174
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0312 0.102
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0122 0.0418 0.0619
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0043 0.0143
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0388 0.1274
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0174 0.0258
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0174 0.0174
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0304 0.1249 0.1754
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0238 0.0947 0.0947
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0049 0.0089 0.0089
Entamoeba histolytica phosphomannose isomerase, putative 0.0099 0.0314 0.1033
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0044 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Echinococcus granulosus JmjC domain containing protein 4 0.0237 0.0943 0.0943
Schistosoma mansoni sulfide quinone reductase 0.0057 0.0124 0.0124
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0388 0.1298
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0388 0.0575
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0057 0.0124 0.0124
Mycobacterium ulcerans lipase LipD 0.0079 0.0225 0.1446
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.017 0.0636 0.0636
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0037 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0111 0.0369 0.1217
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0057 0.0124 0.0184
Schistosoma mansoni microtubule-associated protein tau 0.223 1 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0215 0.0841 0.1246
Brugia malayi beta-lactamase family protein 0.0079 0.0225 0.0333
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.017 0.0636 0.0636
Schistosoma mansoni cpg binding protein 0.0095 0.0296 0.0296
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0215 0.0841 0.3136
Brugia malayi jmjC domain containing protein 0.0897 0.3941 0.5839
Schistosoma mansoni thyroid hormone receptor 0.0084 0.0246 0.0246
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0084 0.0246 0.0246
Echinococcus granulosus expressed protein 0.0032 0.0012 0.0012
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0032 0.0033
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0774 0.3381 0.3381
Schistosoma mansoni steroid hormone receptor ad4bp 0.0084 0.0246 0.0246
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0225 0.0288
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0057 0.0124 0.0462
Onchocerca volvulus 0.0085 0.0249 0.0284
Brugia malayi Protein cec-1. 0.0037 0.0032 0.0047
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0043 0.0043
Plasmodium falciparum thioredoxin reductase 0.062 0.2681 1
Trypanosoma brucei heat shock protein, putative 0.0098 0.0312 0.1045
Schistosoma mansoni protein phosphatase 2C 0.0237 0.0943 0.0943
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0139 0.0206
Echinococcus granulosus endoplasmin 0.0078 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0088 0.0265 0.0393
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0209 0.0815 0.0815
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0081 0.0081
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0057 0.0124 0.0143
Brugia malayi jmjC domain containing protein 0.0237 0.0943 0.1397
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0623 0.2698 0.3498
Entamoeba histolytica hypothetical protein 0.0116 0.0392 0.1295
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0219 0.086 0.086
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0047
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Echinococcus granulosus histone acetyltransferase MYST2 0.0222 0.0875 0.0875
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0084 0.0246 0.0246
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0222 0.0875 0.0875
Loa Loa (eye worm) hypothetical protein 0.0084 0.0246 0.0365
Leishmania major trypanothione reductase 0.062 0.2681 0.8966
Echinococcus granulosus chromobox protein 1 0.0224 0.0884 0.0884
Treponema pallidum thioredoxin reductase (trxB) 0.0057 0.0124 0.0437
Schistosoma mansoni heat shock protein 0.004 0.0048 0.0048
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.1413 0.6289 0.8973
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0084 0.0246 0.0365
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO 0.0054 0.0109 0.0121
Loa Loa (eye worm) MH2 domain-containing protein 0.005 0.0092 0.0136
Schistosoma mansoni chromobox protein 0.0224 0.0884 0.0884
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0084 0.0246 0.0246
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0215 0.0841 0.2793
Echinococcus multilocularis musashi 0.0056 0.0122 0.0122
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.062 0.2681 0.3806
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1571 0.7005 1
Trichomonas vaginalis CAMK family protein kinase 0.0687 0.2989 0.3878
Treponema pallidum oxidoreductase 0.0057 0.0124 0.0437
Mycobacterium tuberculosis Putative ferredoxin reductase 0.1413 0.6289 0.8973
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0215 0.0841 0.2793
Schistosoma mansoni hypothetical protein 0.0085 0.0249 0.0249
Schistosoma mansoni aldehyde dehydrogenase 0.0317 0.1304 0.1304
Toxoplasma gondii PHD-finger domain-containing protein 0.004 0.0048 0.0181
Trichomonas vaginalis chromobox protein, putative 0.0224 0.0884 0.1141
Loa Loa (eye worm) hypothetical protein 0.0053 0.0106 0.0157
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0174 0.0563
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.011 0.0364 0.0539
Echinococcus multilocularis glutamate synthase 0.0057 0.0124 0.0124
Plasmodium vivax heat shock protein 86, putative 0.0098 0.0312 0.1165
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0225 0.0284
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0078 0.0221 0.0221
Trichomonas vaginalis chromobox protein, putative 0.0135 0.0479 0.0615
Brugia malayi nuclear hormone receptor 0.004 0.0045 0.0066
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0057 0.0124 0.0388
Brugia malayi hypothetical protein 0.0044 0.0066 0.0098
Brugia malayi hypothetical protein 0.0085 0.0249 0.037
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0049 0.0049
Schistosoma mansoni rab6-interacting 0.0085 0.0249 0.0249
Echinococcus granulosus thioredoxin glutathione reductase 0.0623 0.2698 0.2698
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0235 0.0297
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0084 0.0246 0.0246
Schistosoma mansoni smad1 5 8 and 0.005 0.0092 0.0092
Onchocerca volvulus 0.017 0.0636 0.0788
Schistosoma mansoni hypothetical protein 0.0035 0.0023 0.0023
Loa Loa (eye worm) mbt repeat family protein 0.0195 0.0752 0.1115
Brugia malayi hypothetical protein 0.0037 0.0032 0.0047
Schistosoma mansoni hypothetical protein 0.0317 0.1307 0.1307
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0037 0.0032 0.0047
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Plasmodium falciparum ferrodoxin reductase-like protein 0.0057 0.0124 0.0462
Loa Loa (eye worm) nuclear receptor NHR-67 0.004 0.0045 0.0066
Schistosoma mansoni hypothetical protein 0.0124 0.0427 0.0427
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0035 0.0025 0.0025
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0084 0.0246 0.0246
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0057 0.0124 0.0124
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA 0.0099 0.0314 0.2154
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0317 0.1304 0.1833
Trypanosoma brucei phosphomannose isomerase 0.0099 0.0314 0.1052
Echinococcus multilocularis jumonji domain containing 1A 0.0237 0.0943 0.0943
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0122 0.018
Loa Loa (eye worm) hypothetical protein 0.0237 0.0943 0.1397
Loa Loa (eye worm) programmed cell death 8 0.0057 0.0124 0.0184
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0084 0.0246 0.0365
Loa Loa (eye worm) hypothetical protein 0.0932 0.4101 0.6076
Schistosoma mansoni endoplasmin 0.0098 0.0312 0.0312
Plasmodium falciparum thioredoxin reductase 0.0215 0.0841 0.3136
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0436 0.0559
Loa Loa (eye worm) hypothetical protein 0.0124 0.0427 0.0632
Brugia malayi Pax transcription factor protein 2 0.0233 0.0922 0.1366
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.1413 0.6289 0.8973
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0057 0.0124 0.0143
Trichomonas vaginalis rotamase, putative 0.0032 0.0012 0.0007
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0388 0.0521
Brugia malayi photoreceptor-specific nuclear receptor 0.0084 0.0246 0.0365
Schistosoma mansoni hypothetical protein 0.0046 0.0074 0.0074
Trypanosoma brucei polo-like protein kinase 0.0687 0.2989 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.011 0.0364 0.0539
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0057 0.0124 0.0143
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0047
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0044 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.008 0.0096
Echinococcus granulosus phd:f box containing protein 0.0237 0.0943 0.0943
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0057 0.0124 0.0388
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0225 0.0288
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0122 0.0151
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0032 0.0085
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0225 0.0288
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0225 0.0288
Echinococcus granulosus Niemann Pick C1 protein 0.0111 0.0369 0.0369
Schistosoma mansoni glutamate synthase 0.0057 0.0124 0.0124
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0057 0.0124 0.0462
Trichomonas vaginalis heat shock protein, putative 0.0078 0.0221 0.0279
Trichomonas vaginalis hypothetical protein 0.0037 0.0032 0.0033
Schistosoma mansoni chromobox protein 0.0224 0.0884 0.0884
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0225 0.0288
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0049 0.0089 0.0271
Brugia malayi nuclear hormone receptor family member nhr-6 0.004 0.0045 0.0066
Loa Loa (eye worm) jmjC domain-containing protein 0.0255 0.1025 0.1518
Trichomonas vaginalis CAMK family protein kinase 0.0687 0.2989 0.3878
Brugia malayi isocitrate dehydrogenase 0.0049 0.0089 0.0132
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0237 0.0943 0.3137
Schistosoma mansoni Smad4 0.005 0.0092 0.0092
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0317 0.1304 0.1304
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0032 0.0033
Schistosoma mansoni glutamate synthase 0.0057 0.0124 0.0124
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0388 0.0575
Loa Loa (eye worm) hypothetical protein 0.0048 0.0081 0.012
Brugia malayi Inositol-1 0.0039 0.0043 0.0063
Plasmodium vivax mannose-6-phosphate isomerase, putative 0.0099 0.0314 0.1173
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0066 0.0098
Trypanosoma cruzi heat shock protein 90, putative 0.0058 0.0129 0.0405
Brugia malayi Niemann-Pick C1 protein precursor 0.0111 0.0369 0.0547
Schistosoma mansoni heat shock protein 0.0098 0.0312 0.0312
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0195 0.0752 0.094
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Schistosoma mansoni jumonji domain containing protein 0.0237 0.0943 0.0943
Loa Loa (eye worm) hypothetical protein 0.0075 0.0206 0.0305
Echinococcus granulosus chromobox protein 1 0.0224 0.0884 0.0884
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0215 0.0841 0.2793
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0084 0.0246 0.0246
Brugia malayi jmjC domain containing protein 0.0237 0.0943 0.1397
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0006 0.0023
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0044 0.0066 0.0098
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0623 0.2698 0.9022
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0045 0.0045
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0044 0.0066 0.0066
Schistosoma mansoni lozenge 0.0117 0.0396 0.0396
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0225 0.1446
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0225 0.0333
Brugia malayi 6-phosphofructokinase 0.0115 0.0388 0.0575
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0057 0.0124 0.0153
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0057 0.0124 0.0124
Toxoplasma gondii selenide, water dikinase 0.0057 0.0124 0.0462
Echinococcus multilocularis snurportin 1 0.0317 0.1307 0.1307
Schistosoma mansoni hypothetical protein 0.0037 0.0032 0.0032
Echinococcus multilocularis GPCR, family 2 0.0035 0.0023 0.0023
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0687 0.2989 0.4429
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0225 0.084
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0002 0.0004
Schistosoma mansoni myelin transcription factor 1 myt1 0.0222 0.0875 0.0875
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0084 0.0246 0.0365
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0124 0.0427 0.0427
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0089 0.0271
Trichomonas vaginalis heat shock protein, putative 0.0078 0.0221 0.0279
Echinococcus multilocularis lysine specific demethylase 5A 0.089 0.3908 0.3908
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0174 0.0174
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0215 0.0841 0.2793
Schistosoma mansoni hypothetical protein 0.004 0.0048 0.0048
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0215 0.0841 0.2793
Plasmodium falciparum heat shock protein 90, putative 0.004 0.0048 0.018
Entamoeba histolytica disulphide oxidoreductase, putative 0.0057 0.0124 0.0395
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0159 0.0921
Loa Loa (eye worm) MBCTL1 0.0222 0.0875 0.1297
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0057 0.0124 0.0124
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0084 0.0246 0.0246
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0084 0.0246 0.0246
Loa Loa (eye worm) heterochromatin protein 1 0.0224 0.0884 0.131
Echinococcus granulosus peregrin 0.0126 0.0439 0.0439
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0049 0.0089 0.0093
Brugia malayi MH2 domain containing protein 0.0732 0.3194 0.4732
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0312 0.102
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0135 0.0479 0.0584
Chlamydia trachomatis thioredoxin reductase 0.0057 0.0124 0.141
Echinococcus granulosus ecdysone induced protein 78C 0.0084 0.0246 0.0246
Mycobacterium ulcerans aldehyde dehydrogenase 0.0317 0.1304 1
Leishmania major phosphomannose isomerase 0.0099 0.0314 0.1027
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0084 0.0246 0.0246
Echinococcus granulosus heat shock protein 90 0.0078 0.0221 0.0221
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0194 0.0194
Schistosoma mansoni glutamate synthase 0.0057 0.0124 0.0124
Schistosoma mansoni transcription factor LCR-F1 0.0116 0.0392 0.0392
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0045 0.0045
Brugia malayi Nuclear hormone receptor-like 1 0.0084 0.0246 0.0365
Brugia malayi glutamate synthase 0.0057 0.0124 0.0184
Echinococcus granulosus lysine specific demethylase 5A 0.0897 0.3941 0.3941
Trypanosoma brucei heat shock protein, putative 0.0098 0.0312 0.1045
Plasmodium vivax heterochromatin protein 1, putative 0.0037 0.0032 0.0118
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0174 0.0174
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Leishmania major hypothetical protein, conserved 0.0057 0.0124 0.0388
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0081 0.0235 0.0348
Schistosoma mansoni hypothetical protein 0.0046 0.0074 0.0074
Loa Loa (eye worm) CHromoDomain protein family member 0.0044 0.0064 0.0095
Mycobacterium ulcerans beta-lactamase 0.0079 0.0225 0.1446
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0057 0.0124 0.0462
Trichomonas vaginalis CAMK family protein kinase 0.0687 0.2989 0.3878
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0057 0.0124 0.0395
Leishmania major heat shock protein 83-1 0.0098 0.0312 0.102
Echinococcus multilocularis Niemann Pick C1 protein 0.0159 0.0586 0.0586
Trichomonas vaginalis glutamate synthase, putative 0.0057 0.0124 0.0153
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0057 0.0124 0.0184
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0006 0.0023
Brugia malayi Pre-SET motif family protein 0.1515 0.6749 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0623 0.2698 0.9022
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0265 0.0265
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0084 0.0246 0.0246
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.1145 0.5068 0.5068
Trypanosoma brucei heat shock protein, putative 0.0098 0.0312 0.1045
Loa Loa (eye worm) hypothetical protein 0.0081 0.0235 0.0348
Schistosoma mansoni thyroid hormone receptor 0.0084 0.0246 0.0246
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0084 0.0246 0.0246
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0037 0.0032 0.0118
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0099 0.0314 0.0466
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0058 0.013 0.0193
Leishmania major hypothetical protein, conserved 0.0057 0.0124 0.0388
Echinococcus multilocularis protein dispatched 1 0.0054 0.0112 0.0112
Loa Loa (eye worm) jmjC domain-containing protein 0.0237 0.0943 0.1397
Brugia malayi hypothetical protein 0.0044 0.0066 0.0098
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0084 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0079 0.0225 0.0333
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0222 0.0875 0.1297
Echinococcus granulosus heat shock protein 90 0.0098 0.0312 0.0312
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.1145 0.5068 0.5068
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0174 0.0258
Trypanosoma brucei NADH dehydrogenase 0.0057 0.0124 0.0415
Onchocerca volvulus 0.004 0.0045 0.0017
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0057 0.0124 0.0462
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0002 0.0004
Entamoeba histolytica thioredoxin reductase, putative 0.0057 0.0124 0.0395
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0237 0.0943 0.0943
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0225 0.0225
Echinococcus granulosus lamin 0.0056 0.0122 0.0122
Brugia malayi hypothetical protein 0.0116 0.0392 0.0581
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0084 0.0246 0.0246
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0089 0.0089
Brugia malayi nuclear receptor NHR-88 0.0084 0.0246 0.0365
Brugia malayi jmjC domain containing protein 0.1145 0.5068 0.7509
Brugia malayi PHD-finger family protein 0.0033 0.0015 0.0023
Onchocerca volvulus 0.0057 0.0124 0.012
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0084 0.0246 0.0365
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0388 0.0496
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0084 0.0246 0.0365
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0388 0.0388
Onchocerca volvulus Protein ultraspiracle homolog 0.0084 0.0246 0.028
Giardia lamblia Glutamate synthase 0.0057 0.0124 0.0395
Echinococcus multilocularis TGF beta signal transducer SmadC 0.005 0.0092 0.0092
Onchocerca volvulus 0.0085 0.0249 0.0284
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0623 0.2698 0.3498
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0057 0.0124 0.0143
Loa Loa (eye worm) hypothetical protein 0.0048 0.0081 0.0121
Echinococcus granulosus transcription factor eb 0.0122 0.0418 0.0418
Brugia malayi jmjC domain containing protein 0.0237 0.0943 0.1397
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0774 0.3381 0.3381
Echinococcus multilocularis jumonji domain containing protein 0.0172 0.0646 0.0646
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0304 0.1249 0.9561
Trichomonas vaginalis glutamate synthase, putative 0.0057 0.0124 0.0153
Schistosoma mansoni jumonji/arid domain-containing protein 0.0897 0.3941 0.3941
Toxoplasma gondii heat shock protein 75, putative 0.004 0.0048 0.018
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0099 0.0314 0.0466
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0037 0.0032 0.0118
Loa Loa (eye worm) hypothetical protein 0.0079 0.0225 0.0333
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0057 0.0124 0.0462
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0237 0.0943 0.3518
Echinococcus multilocularis transcription factor eb 0.0122 0.0418 0.0418
Brugia malayi orphan nuclear receptor NR2E1 0.004 0.0045 0.0066
Trypanosoma cruzi heat shock protein 90, putative 0.0098 0.0312 0.102
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0623 0.2698 0.3498
Plasmodium vivax SET domain protein, putative 0.0219 0.086 0.3207
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0237 0.0943 0.3518
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0084 0.0246 0.0365
Echinococcus multilocularis RUN 0.0085 0.0249 0.0249
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0215 0.0841 0.2793
Trypanosoma cruzi heat shock protein 90, putative 0.0078 0.0221 0.0715
Brugia malayi hypothetical protein 0.0085 0.0249 0.037
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0057 0.0124 0.0644
Echinococcus granulosus polycomb protein SCMH1 0.0195 0.0752 0.0752
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.004 0.0045 0.0066
Giardia lamblia Heat shock protein HSP 90-alpha 0.0098 0.0312 0.1026
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0057 0.0124 0.0124
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0195 0.0752 0.0752
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.0023 0.0023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0057 0.0124 0.0153
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0066
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0388 0.0388
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0078 0.0221 0.0282
Echinococcus granulosus heat shock protein 0.0098 0.0312 0.0312
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0032 0.0033
Schistosoma mansoni zinc finger protein 0.004 0.0045 0.0045
Brugia malayi RNA, U transporter 1 0.0084 0.0249 0.0369
Brugia malayi F/Y-rich N-terminus family protein 0.0077 0.0216 0.0321
Echinococcus granulosus lipoxygenase domain containing protein 0.0085 0.0249 0.0249
Echinococcus multilocularis Chromo domain 0.0037 0.0032 0.0032
Plasmodium falciparum phd finger protein, putative 0.0124 0.0427 0.1591
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0032 0.0033
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0057 0.0124 0.0153

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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