Detailed information for compound 1152334

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 274.315 | Formula: C15H18N2O3
  • H donors: 1 H acceptors: 3 LogP: 1.46 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: N[C@H](C(=O)CN1C(=O)c2c(C1=O)cccc2)CC(C)C
  • InChi: 1S/C15H18N2O3/c1-9(2)7-12(16)13(18)8-17-14(19)10-5-3-4-6-11(10)15(17)20/h3-6,9,12H,7-8,16H2,1-2H3/t12-/m0/s1
  • InChiKey: VBVVFXXHFOCAJY-LBPRGKRZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni multidrug resistance protein 0.0063 0.2093 0.2093
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0196 1 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.2093 0.2093
Brugia malayi ABC transporter family protein 0.0063 0.2093 0.2093
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0196 1 1
Schistosoma mansoni multidrug resistance protein 0.0196 1 1
Trypanosoma brucei p-glycoprotein 0.0063 0.2093 0.2107
Entamoeba histolytica P-glycoprotein 5, putative 0.0058 0.1842 0.1842
Entamoeba histolytica ATP-binding cassette protein, putative 0.0063 0.2093 0.2093
Schistosoma mansoni tar DNA-binding protein 0.0077 0.2938 0.2938
Toxoplasma gondii ATP-binding cassette G family transporter ABCG107 0.0032 0.0251 0.0066
Plasmodium vivax ABC transporter B family member 4, putative 0.0063 0.2093 0.1943
Brugia malayi RNA recognition motif domain containing protein 0.0077 0.2938 0.2938
Trypanosoma brucei ATP-binding cassette protein subfamily G 0.0032 0.0251 0.0072
Entamoeba histolytica multidrug resistance protein, putative 0.0063 0.2093 0.2093
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0063 0.2093 0.2266
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0077 0.2938 0.2938
Plasmodium vivax multidrug resistance protein 1, putative 0.0196 1 1
Schistosoma mansoni tar DNA-binding protein 0.0077 0.2938 0.2938
Plasmodium falciparum multidrug resistance-associated protein 1 0.0063 0.2093 0.1943
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0058 0.1842 0.1842
Echinococcus granulosus multidrug resistance protein 1 0.0196 1 1
Trypanosoma brucei ABC transporter, putative 0.0032 0.0251 0.0072
Schistosoma mansoni hypothetical protein 0.0041 0.0826 0.0826
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0196 1 1
Toxoplasma gondii ATP-binding cassette G family transporter ABCG96 0.0032 0.0251 0.0066
Brugia malayi RNA binding protein 0.0077 0.2938 0.2938
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0196 1 0.5
Schistosoma mansoni multidrug resistance protein 0.0063 0.2093 0.2093
Loa Loa (eye worm) hypothetical protein 0.0063 0.2093 0.2093
Trypanosoma cruzi PAB1-binding protein , putative 0.0031 0.0186 0.0201
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0196 1 1
Schistosoma mansoni multidrug resistance protein 0.0063 0.2093 0.2093
Loa Loa (eye worm) transcription factor SMAD2 0.0145 0.6982 0.6982
Trypanosoma cruzi multidrug resistance protein E, putative 0.0063 0.2093 0.2266
Leishmania major ATP-binding cassette protein subfamily G, member 2, putative 0.0032 0.0251 0.0066
Echinococcus multilocularis ATP binding cassette sub family B 0.0191 0.9749 0.9683
Loa Loa (eye worm) hypothetical protein 0.0058 0.1842 0.1842
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0183 0.9236 0.9222
Entamoeba histolytica P-glycoprotein 5, putative 0.0196 1 1
Leishmania major ABC-thiol transporter 0.0063 0.2093 0.1943
Schistosoma mansoni tar DNA-binding protein 0.0077 0.2938 0.2938
Brugia malayi TAR-binding protein 0.0077 0.2938 0.2938
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0063 0.2093 0.1943
Leishmania major p-glycoprotein e 0.0063 0.2093 0.1943
Toxoplasma gondii ABC transporter, putative 0.0063 0.2093 0.1943
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0826 0.0826
Loa Loa (eye worm) RNA binding protein 0.0077 0.2938 0.2938
Entamoeba histolytica P-glycoprotein-2, putative 0.0196 1 1
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0191 0.9749 0.9692
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0063 0.2093 0.1943
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0196 1 1
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0063 0.2093 0.2266
Giardia lamblia ABC transporter, putative 0.0063 0.2093 0.0351
Toxoplasma gondii ATP-binding cassette G family transporter ABCG89 0.0032 0.0251 0.0066
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0063 0.2093 0.2266
Plasmodium vivax ABC transporter B family member 3, putative 0.0063 0.2093 0.1943
Echinococcus granulosus ATP binding cassette sub family G 0.0183 0.9236 0.9064
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.1964 0.1964
Echinococcus multilocularis tar DNA binding protein 0.0077 0.2938 0.1069
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0063 0.2093 0.2093
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0251 0.0272
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0196 1 1
Echinococcus granulosus multidrug resistance protein 1 0.0196 1 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0196 1 1
Entamoeba histolytica P-glycoprotein-5 0.0196 1 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0196 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0196 1 1
Brugia malayi hypothetical protein 0.0063 0.2093 0.2093
Entamoeba histolytica hypothetical protein 0.0063 0.2093 0.2093
Echinococcus granulosus ATP binding cassette sub family B 0.0063 0.2093 0.0308
Giardia lamblia Multidrug resistance-associated protein 1 0.0063 0.2093 0.0351
Loa Loa (eye worm) ABC transporter 0.0063 0.2093 0.2093
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0063 0.2093 0.0308
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0063 0.2093 0.2093
Schistosoma mansoni multidrug resistance protein 0.0196 1 1
Onchocerca volvulus 0.0196 1 0.5
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0183 0.9236 0.9236
Plasmodium falciparum ABC transporter G family member 2 0.0183 0.9236 0.9222
Giardia lamblia Multidrug resistance-associated protein 1 0.0063 0.2093 0.0351
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0196 1 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0196 1 1
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0063 0.2093 0.2266
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0063 0.2093 0.2266
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0063 0.2093 0.5
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0063 0.2093 0.2266
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0196 1 1
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0063 0.2093 0.2093
Loa Loa (eye worm) hypothetical protein 0.0196 1 1
Plasmodium vivax ABC transporter B family member 7, putative 0.0063 0.2093 0.1943
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0063 0.2093 0.1943
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0196 1 1
Brugia malayi ABC transporter family protein 0.0063 0.2093 0.2093
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0063 0.2093 0.2107
Plasmodium falciparum multidrug resistance protein 1 0.0196 1 1
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0063 0.2093 0.2266
Leishmania major ATP-binding cassette protein subfamily G, member 1, putative 0.0032 0.0251 0.0066
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0137 0.6525 0.5741
Schistosoma mansoni ABC transporter 0.0155 0.7603 0.7603
Echinococcus multilocularis multidrug resistance protein 1 0.0196 1 1
Entamoeba histolytica P-glycoprotein-2 0.0196 1 1
Trichomonas vaginalis ABC transporter, putative 0.0196 1 1
Echinococcus granulosus multidrug resistance protein 1 0.0137 0.6525 0.5741
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0063 0.2093 0.2093
Trypanosoma cruzi ATP-binding cassette protein subfamily G 0.0032 0.0251 0.0272
Trypanosoma brucei ATP-binding cassette protein, putative 0.0183 0.9236 1
Plasmodium falciparum ABC transporter B family member 3, putative 0.0063 0.2093 0.1943
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0196 1 1
Echinococcus granulosus ATP binding cassette sub family B 0.0063 0.2093 0.0308
Brugia malayi multidrug resistance related protein 1 0.0063 0.2093 0.2093
Trichomonas vaginalis ABC transporter, putative 0.0196 1 1
Brugia malayi ABC transporter transmembrane region family protein 0.0058 0.1842 0.1842
Plasmodium vivax ABC transporter B family member 6, putative 0.0063 0.2093 0.1943
Entamoeba histolytica P-glyco protein 6, putative 0.0196 1 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0196 1 1
Entamoeba histolytica P-glycoprotein 6, putative 0.0063 0.2093 0.2093
Loa Loa (eye worm) hypothetical protein 0.0058 0.1842 0.1842
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0183 0.9236 1
Trichomonas vaginalis ABC transporter, putative 0.0196 1 1
Entamoeba histolytica ABC transporter, putative 0.0183 0.9236 0.9236
Trypanosoma cruzi PAB1-binding protein , putative 0.0031 0.0186 0.0201
Entamoeba histolytica P-glycoprotein 6, putative 0.0063 0.2093 0.2093
Plasmodium falciparum ABC transporter B family member 5, putative 0.0063 0.2093 0.1943
Schistosoma mansoni multidrug resistance protein 0.0063 0.2093 0.2093
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0196 1 1
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0063 0.2093 0.2093
Leishmania major pentamidine resistance protein 1 0.0063 0.2093 0.1943
Schistosoma mansoni hypothetical protein 0.0151 0.7352 0.7352
Echinococcus granulosus tar DNA binding protein 0.0077 0.2938 0.1344
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0183 0.9236 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0196 1 1
Plasmodium falciparum ABC transporter B family member 6, putative 0.0063 0.2093 0.1943
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0063 0.2093 0.2107
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0063 0.2093 1
Schistosoma mansoni multidrug resistance protein 0.0063 0.2093 0.2093
Echinococcus granulosus ATP binding cassette sub family G 0.0183 0.9236 0.9064
Loa Loa (eye worm) MH2 domain-containing protein 0.0145 0.6982 0.6982
Loa Loa (eye worm) hypothetical protein 0.006 0.1964 0.1964
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0063 0.2093 0.2266
Loa Loa (eye worm) ABC transporter 0.0063 0.2093 0.2093
Toxoplasma gondii ABC transporter family protein 0.0063 0.2093 0.1943
Echinococcus granulosus multidrug resistance protein 1 0.0137 0.6525 0.5741
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0063 0.2093 0.1943
Loa Loa (eye worm) hypothetical protein 0.0063 0.2093 0.2093
Echinococcus multilocularis ATP binding cassette sub family G 0.0183 0.9236 0.9034
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0063 0.2093 0.1943
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0196 1 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0186 0.0186
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0063 0.2093 0.5
Loa Loa (eye worm) TAR-binding protein 0.0077 0.2938 0.2938
Echinococcus granulosus multidrug resistance protein 1 0.0196 1 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.1964 0.1964
Loa Loa (eye worm) ABC transporter 0.0155 0.7603 0.7603
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0183 0.9236 0.9222
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0063 0.2093 0.1943
Entamoeba histolytica P-glycoprotein-1 0.0196 1 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0063 0.2093 0.2093
Brugia malayi hypothetical protein 0.0031 0.0186 0.0186
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0196 1 1
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0063 0.2093 0.1943
Echinococcus granulosus multidrug resistance associated protein 1 0.0063 0.2093 0.0308
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0196 1 1
Echinococcus multilocularis multidrug resistance protein 1 0.0137 0.6525 0.5606
Echinococcus multilocularis ATP binding cassette sub family G 0.0183 0.9236 0.9034
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0063 0.2093 0.2107
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0196 1 1
Entamoeba histolytica P-glycoprotein-2, putative 0.0058 0.1842 0.1842
Leishmania major p-glycoprotein 0.0196 1 1
Brugia malayi ABC transporter family protein 0.0155 0.7603 0.7603
Trypanosoma cruzi ATP-binding cassette protein subfamily G 0.0032 0.0251 0.0272
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0196 1 1
Echinococcus multilocularis multidrug resistance protein 1 0.0196 1 1
Brugia malayi ABC transporter 0.0058 0.1842 0.1842
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0151 0.7352 0.7352
Echinococcus multilocularis ATP binding cassette sub family G 0.0183 0.9236 0.9034
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0183 0.9236 1
Leishmania major ATP-binding cassette protein subfamily G, member 5, putative 0.0032 0.0251 0.0066
Trypanosoma cruzi ABC transporter, putative 0.0183 0.9236 1
Plasmodium vivax multidrug resistance protein 2, putative 0.0063 0.2093 0.1943
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0196 1 1
Trichomonas vaginalis abcb9, putative 0.0196 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0196 1 1
Schistosoma mansoni multidrug resistance protein 0.0196 1 1
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0063 0.2093 0.1943
Entamoeba histolytica ATP-binding cassette protein, putative 0.0063 0.2093 0.2093
Brugia malayi ABC transporter 0.0063 0.2093 0.2093
Brugia malayi ABC transporter family protein 0.0063 0.2093 0.2093
Entamoeba histolytica P-glycoprotein-2 0.0196 1 1
Giardia lamblia ABC transporter 0.0178 0.8985 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0196 1 1
Entamoeba histolytica ABC transporter, putative 0.0063 0.2093 0.2093
Schistosoma mansoni smdr1 0.0063 0.2093 0.2093
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0063 0.2093 0.1943
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0196 1 1
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0196 1 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0826 0.0826
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0063 0.2093 0.1943
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0063 0.2093 0.1943
Plasmodium falciparum ABC transporter B family member 4, putative 0.0063 0.2093 0.1943
Schistosoma mansoni tar DNA-binding protein 0.0077 0.2938 0.2938
Trichomonas vaginalis abcb9, putative 0.0196 1 1
Brugia malayi P-glycoprotein-like protein 0.0063 0.2093 0.2093
Plasmodium vivax ABC transporter B family member 5, putative 0.0063 0.2093 0.1943
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0196 1 1
Schistosoma mansoni multidrug resistance protein 0.0058 0.1842 0.1842
Brugia malayi ABC transporter transmembrane region family protein 0.0063 0.2093 0.2093
Echinococcus granulosus multidrug resistance associated protein 7 0.0063 0.2093 0.0308
Brugia malayi ABC transporter family protein 0.0196 1 1
Giardia lamblia MRP-like ABC transporter 0.0063 0.2093 0.0351
Schistosoma mansoni tar DNA-binding protein 0.0077 0.2938 0.2938
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0251 0.0272
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0196 1 1
Echinococcus granulosus ATP binding cassette sub family G 0.0183 0.9236 0.9064
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0063 0.2093 0.2107
Trypanosoma brucei ABC transporter, putative 0.0183 0.9236 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0196 1 1
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0063 0.2093 0.1943
Loa Loa (eye worm) hypothetical protein 0.0191 0.9749 0.9749
Plasmodium falciparum ABC transporter B family member 7, putative 0.0063 0.2093 0.1943
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0196 1 1
Loa Loa (eye worm) hypothetical protein 0.0196 1 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0196 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0196 1 1
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0196 1 1
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0063 0.2093 1
Schistosoma mansoni smdr2 0.0196 1 1
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0183 0.9236 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0063 0.2093 0.1943
Brugia malayi ABC transporter transmembrane region family protein 0.0063 0.2093 0.2093
Plasmodium falciparum multidrug resistance-associated protein 2 0.0063 0.2093 0.1943
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.1964 0.1964
Trichomonas vaginalis ABC transporter, putative 0.0196 1 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0196 1 1
Loa Loa (eye worm) ABC transporter 0.0063 0.2093 0.2093
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0063 0.2093 0.1943
Trichomonas vaginalis abcb9, putative 0.0196 1 1
Brugia malayi MH2 domain containing protein 0.0145 0.6982 0.6982
Plasmodium falciparum multidrug resistance protein 2 0.0063 0.2093 0.1943
Entamoeba histolytica ATP-binding cassette protein, putative 0.0063 0.2093 0.2093
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0063 0.2093 0.1943
Toxoplasma gondii ATP-binding cassette G family transporter ABCG87 0.0032 0.0251 0.0066
Trichomonas vaginalis taga, putative 0.0196 1 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0063 0.2093 0.2266
Loa Loa (eye worm) multidrug resistance protein 3 0.0196 1 1
Plasmodium vivax ABC transporter G family member 2, putative 0.0183 0.9236 0.9222
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0183 0.9236 0.9222
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0063 0.2093 0.1943
Trypanosoma brucei multidrug resistance protein E 0.0063 0.2093 0.2107
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0196 1 1
Trypanosoma cruzi ABC transporter, putative 0.0032 0.0251 0.0272

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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