Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | musashi | 0.003 | 0.3662 | 0.4566 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.3662 | 0.3662 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.7692 | 0.7692 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0276 | 0.0276 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.5499 | 0.5499 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.7692 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.7692 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0276 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.3518 | 0.3518 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 1 | 1 |
Onchocerca volvulus | 0.003 | 0.3662 | 0.5 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.7692 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.3662 | 0.4566 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.7692 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.7692 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.3662 | 0.4566 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.5499 | 0.5499 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.3662 | 0.4566 |
Onchocerca volvulus | 0.003 | 0.3662 | 0.5 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.7692 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0276 | 0.0276 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.3662 | 0.3662 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.3662 | 0.4566 |
Schistosoma mansoni | lamin | 0.003 | 0.3662 | 0.4566 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.3662 | 0.3662 |
Echinococcus granulosus | lamin | 0.003 | 0.3662 | 0.4566 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.3662 | 0.3662 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0276 | 0.0276 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.7692 | 0.7692 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.5499 | 0.7043 |
Brugia malayi | intermediate filament protein | 0.003 | 0.3662 | 0.3662 |
Schistosoma mansoni | lamin | 0.003 | 0.3662 | 0.4566 |
Echinococcus multilocularis | lamin | 0.003 | 0.3662 | 0.4566 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.7692 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.