Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.9254 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0071 | 0.7967 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.0851 | 0.0678 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.2574 | 0.2935 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.3186 | 0.3737 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.4755 | 0.5139 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.2276 | 0.2544 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.4357 | 0.4709 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.2574 | 0.2935 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.4755 | 0.3997 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.4755 | 0.5139 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.2574 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0043 | 0.3599 | 0.2673 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0067 | 0.7332 | 0.9167 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.4024 | 0.4348 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0025 | 0.0851 | 0.0678 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0071 | 0.7967 | 0.7673 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.3611 | 0.3902 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.2574 | 0.2935 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.2574 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.2574 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.7967 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.7967 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.7967 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0071 | 0.7956 | 0.9985 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.2276 | 0.2459 |
Loa Loa (eye worm) | RNA binding protein | 0.0071 | 0.7967 | 0.861 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.7967 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0071 | 0.7967 | 0.861 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0025 | 0.0851 | 0.0678 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.4755 | 0.3997 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.2276 | 0.1158 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.2574 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.7967 | 1 |
Brugia malayi | TAR-binding protein | 0.0071 | 0.7967 | 0.7673 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0023 | 0.0518 | 0.0559 |
Brugia malayi | hypothetical protein | 0.0036 | 0.2574 | 0.15 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0518 | 0.0241 |
Loa Loa (eye worm) | TAR-binding protein | 0.0071 | 0.7967 | 0.861 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.2574 | 0.2935 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0067 | 0.7332 | 0.9167 |
Brugia malayi | RNA binding protein | 0.0071 | 0.7967 | 0.7673 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.3186 | 0.3737 |
Echinococcus granulosus | tar DNA binding protein | 0.0071 | 0.7967 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.