Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Thioredoxin reductase | 0.0049 | 0.0053 | 0.0053 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0008 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0057 | 0.0063 | 0.192 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0057 | 0.0063 | 0.0054 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0013 | 0.0034 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.0053 | 0.0043 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.0026 | 0.0788 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0039 | 0.0039 | 0.003 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.0013 | 0.0004 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0017 | 0.001 | 0.0005 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.7414 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0039 | 0.0039 | 0.003 |
Brugia malayi | DnaJ domain containing protein | 0.0061 | 0.0069 | 0.0069 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0019 | 0.0019 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.001 | 0.001 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0039 | 0.0039 | 0.003 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0033 | 0.0032 | 0.0082 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2899 | 0.3903 | 1 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.7414 | 1 | 1 |
Schistosoma mansoni | Smad4 | 0.0017 | 0.001 | 0.001 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0008 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.7414 | 1 | 1 |
Schistosoma mansoni | lamin | 0.0029 | 0.0026 | 0.0026 |
Onchocerca volvulus | 0.0029 | 0.0027 | 0.0288 | |
Schistosoma mansoni | hypothetical protein | 0.0061 | 0.0069 | 0.0069 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0019 | 0.0009 |
Leishmania major | cytochrome p450-like protein | 0.0039 | 0.0039 | 0.003 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2895 | 0.3897 | 0.9984 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0039 | 0.0039 | 0.003 |
Echinococcus granulosus | tumor protein p63 | 0.0348 | 0.0458 | 0.1172 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0057 | 0.0063 | 0.192 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0027 | 0.0069 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0039 | 0.0039 | 0.003 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0039 | 0.0039 | 0.003 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0013 | 0.0009 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0019 | 0.0019 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0013 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0005 | 0.0154 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.001 | 0.001 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0013 | 0.0013 |
Echinococcus multilocularis | geminin | 0.0167 | 0.0213 | 0.0546 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2899 | 0.3903 | 1 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.2899 | 0.3903 | 1 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0039 | 0.0039 | 0.003 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.0079 | 0.0079 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.7414 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0011 | 0.0321 |
Leishmania major | dihydroorotate dehydrogenase | 0.7414 | 1 | 1 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0017 | 0.001 | 0.0313 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.7414 | 1 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0801 | 0.1069 | 0.2739 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0059 | 0.1792 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.7414 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0013 | 0.0407 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.7414 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0005 | 0.0154 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.0213 | 0.0213 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0039 | 0.0039 | 0.003 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0014 | 0.0006 | 0.0015 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0111 | 0.0137 | 0.0128 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0019 | 0.0013 |
Brugia malayi | MH1 domain containing protein | 0.0017 | 0.001 | 0.001 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0039 | 0.0039 | 0.003 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0124 | 0.0154 | 0.0145 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0037 | 0.0061 |
Brugia malayi | Cytochrome P450 family protein | 0.0057 | 0.0063 | 0.0063 |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.7414 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0013 | 0.0008 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0027 | 0.0027 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0019 | 0.0009 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0017 | 0.001 | 0.001 |
Schistosoma mansoni | lamin | 0.0029 | 0.0026 | 0.0026 |
Echinococcus granulosus | smad | 0.0017 | 0.001 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0011 | 0.0321 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0039 | 0.0039 | 0.003 |
Echinococcus multilocularis | tumor protein p63 | 0.0348 | 0.0458 | 0.1172 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0059 | 0.1792 |
Echinococcus multilocularis | dnaJ subfamily C 6 | 0.0061 | 0.0069 | 0.0176 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0111 | 0.0137 | 0.0119 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0013 | 0.0034 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.001 | 0.0005 |
Echinococcus granulosus | tar DNA binding protein | 0.0068 | 0.0079 | 0.0202 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0011 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0027 | 0.0027 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0017 | 0.001 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.0213 | 0.0213 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.001 | 0.0025 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.0013 | 0.0034 |
Mycobacterium leprae | putative cytochrome p450 | 0.0039 | 0.0039 | 0.0021 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0012 | 0.0004 | 0.0004 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0011 | 0.0001 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0039 | 0.0039 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0036 | 0.11 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0039 | 0.0039 | 0.003 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.001 | 0.001 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0013 | 0.0004 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0059 | 0.0059 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0013 | 0.0008 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0039 | 0.0039 | 0.003 |
Brugia malayi | Cytochrome P450 family protein | 0.0116 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0011 | 0.0321 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0019 | 0.0009 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.0013 | 0.0034 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0011 | 0.0001 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.0026 | 0.0026 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0017 | 0.001 | 0.0025 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0039 | 0.0039 | 0.003 |
Echinococcus granulosus | lamin | 0.0029 | 0.0026 | 0.0067 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0206 | 0.0265 | 0.8019 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0039 | 0.0039 | 0.003 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.7414 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0013 | 0.0008 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0079 | 0.0079 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0037 | 0.0095 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0039 | 0.0039 | 0.003 |
Leishmania major | trypanothione reductase | 0.0049 | 0.0053 | 0.0043 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0049 | 0.0053 | 0.16 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0017 | 0.001 | 0.001 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0013 | 0.0013 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0049 | 0.0053 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0056 | 0.1692 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0039 | 0.0039 | 0.003 |
Echinococcus multilocularis | Smad4 | 0.0017 | 0.001 | 0.0026 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.2899 | 0.3903 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0006 | 0.0176 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0004 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0008 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.2899 | 0.3903 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0037 | 0.0061 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0013 | 0.0013 |
Trypanosoma brucei | cytochrome P450, putative | 0.0057 | 0.0063 | 0.0058 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0013 | 0.0013 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.001 | 0.0025 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0057 | 0.0063 | 0.0054 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0036 | 0.0036 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.001 | 0.0005 |
Brugia malayi | Cytochrome P450 family protein | 0.0057 | 0.0063 | 0.0063 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0049 | 0.0053 | 0.0135 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0008 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0124 | 0.0154 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0011 | 0.0328 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0079 | 0.0079 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0057 | 0.0063 | 0.0054 |
Loa Loa (eye worm) | cytochrome P450 | 0.0039 | 0.0039 | 0.1196 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0031 | 0.0029 | 0.0049 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0037 | 0.0095 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.001 | 0.001 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0025 | 0.0065 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0124 | 0.0154 | 0.0136 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0039 | 0.0039 | 0.0101 |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.7414 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0026 | 0.0789 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0017 | 0.001 | 0.0026 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0017 | 0.001 | 0.0026 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.0026 | 0.0788 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.001 | 0.0025 |
Brugia malayi | Cytochrome P450 family protein | 0.0039 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0017 | 0.001 | 0.0313 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0254 | 0.033 | 1 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0039 | 0.0039 | 0.003 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0039 | 0.0039 | 0.003 |
Brugia malayi | MH2 domain containing protein | 0.0017 | 0.001 | 0.001 |
Onchocerca volvulus | 0.0234 | 0.0303 | 1 | |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.001 | 0.001 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.001 | 0.001 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0039 | 0.0039 | 0.003 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0013 | 0.0034 |
Echinococcus granulosus | Smad4 | 0.0017 | 0.001 | 0.0026 |
Schistosoma mansoni | cytochrome P450 | 0.0039 | 0.0039 | 0.0039 |
Echinococcus multilocularis | 0.0039 | 0.0039 | 0.0101 | |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0012 | 0.0004 | 0.0004 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0039 | 0.0039 | 0.0034 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0036 | 0.0036 | 0.0036 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0004 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0013 | 0.0034 |
Echinococcus granulosus | dnaJ subfamily C 6 | 0.0061 | 0.0069 | 0.0176 |
Brugia malayi | MH1 domain containing protein | 0.0017 | 0.001 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0079 | 0.0079 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.001 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0025 | 0.0767 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0013 | 0.0013 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0004 |
Plasmodium vivax | glutathione reductase, putative | 0.0049 | 0.0053 | 0.0043 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0013 | 0.0004 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0027 | 0.0027 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0039 | 0.0039 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0039 | 0.0039 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.7414 | 1 | 1 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.7414 | 1 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0019 | 0.0009 |
Onchocerca volvulus | 0.0029 | 0.0026 | 0.0261 | |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.001 | 0.0025 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0037 | 0.0061 |
Brugia malayi | MH2 domain containing protein | 0.0017 | 0.001 | 0.001 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0019 | 0.0563 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.001 | 0.0025 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0027 | 0.0069 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0027 | 0.0027 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.2895 | 0.3897 | 0.3891 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0004 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0008 | 0.0239 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.0079 | 0.2385 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0039 | 0.0039 | 0.003 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0008 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0039 | 0.0039 | 0.003 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0039 | 0.0039 | 0.003 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0008 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0027 | 0.0017 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0039 | 0.0039 | 0.003 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0039 | 0.0039 | 0.003 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0008 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0039 | 0.0039 | 0.003 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0013 | 0.0004 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0019 | 0.0013 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0039 | 0.0039 | 0.003 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0039 | 0.0039 | 0.003 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0039 | 0.0039 | 0.003 |
Brugia malayi | MH2 domain containing protein | 0.0254 | 0.033 | 0.033 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0013 | 0.0407 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0008 |
Brugia malayi | RNA binding protein | 0.0068 | 0.0079 | 0.0079 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0011 | 0.0001 |
Echinococcus granulosus | geminin | 0.0167 | 0.0213 | 0.0546 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0004 |
Brugia malayi | cytochrome P450 | 0.0039 | 0.0039 | 0.0039 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0111 | 0.0137 | 0.0128 |
Treponema pallidum | NADH oxidase | 0.0017 | 0.001 | 0.5 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0039 | 0.0039 | 0.0021 |
Toxoplasma gondii | thioredoxin reductase | 0.0049 | 0.0053 | 0.0043 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0039 | 0.0039 | 0.003 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0019 | 0.0013 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0039 | 0.0039 | 0.003 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0019 | 0.0009 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0008 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0111 | 0.0137 | 0.0128 |
Echinococcus multilocularis | musashi | 0.0029 | 0.0026 | 0.0067 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0037 | 0.0061 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0057 | 0.0063 | 0.192 |
Echinococcus multilocularis | tar DNA binding protein | 0.0068 | 0.0079 | 0.0202 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.2899 | 0.3903 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0033 | 0.0032 | 0.0969 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0031 | 0.0029 | 0.0049 |
Trichomonas vaginalis | protein kinase inhibitor, putative | 0.0061 | 0.0069 | 0.0151 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0019 | 0.0563 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0039 | 0.0039 | 0.003 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.2895 | 0.3897 | 0.9984 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0017 | 0.001 | 0.0026 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0254 | 0.033 | 1 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0039 | 0.0039 | 0.003 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.0056 | 0.0056 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0019 | 0.0009 |
Brugia malayi | Smad1 | 0.0017 | 0.001 | 0.001 |
Loa Loa (eye worm) | Smad1 | 0.0017 | 0.001 | 0.0313 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.001 | 0.001 |
Trypanosoma brucei | trypanothione reductase | 0.0049 | 0.0053 | 0.0048 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0013 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0029 | 0.0026 | 0.0026 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0111 | 0.0137 | 0.0128 |
Echinococcus multilocularis | smad | 0.0017 | 0.001 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0026 | 0.0788 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0011 | 0.0001 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0037 | 0.0037 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0027 | 0.0069 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0019 | 0.0563 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0037 | 0.0037 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0039 | 0.0039 | 0.003 |
Loa Loa (eye worm) | glutathione reductase | 0.0049 | 0.0053 | 0.16 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0039 | 0.0039 | 0.003 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0019 | 0.0009 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0036 | 0.0036 | 0.0036 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0049 | 0.0053 | 0.0043 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0019 | 0.0009 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.001 | 0.001 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0039 | 0.0039 | 0.003 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0013 | 0.0004 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.0079 | 0.2385 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0033 | 0.0032 | 0.0082 |
Loa Loa (eye worm) | DnaJ domain-containing protein | 0.0061 | 0.0069 | 0.2082 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.7414 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0027 | 0.0812 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0039 | 0.0039 | 0.003 |
Leishmania major | cytochrome p450-like protein | 0.0057 | 0.0063 | 0.0054 |
Brugia malayi | Pre-SET motif family protein | 0.0206 | 0.0265 | 0.0265 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0039 | 0.0039 | 0.003 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0039 | 0.0039 | 0.003 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0116 | 0.0143 | 0.4346 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0013 | 0.0004 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0019 | 0.0009 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2895 | 0.3897 | 0.9984 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.001 | 0.0297 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0039 | 0.0039 | 0.003 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0013 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0011 | 0.0321 |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.0053 | 0.0043 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0124 | 0.0154 | 0.0145 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.001 | 0.001 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0017 | 0.001 | 0.0025 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.001 | 0.0297 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.0026 | 0.0067 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.0013 | 0.0004 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.0026 | 0.0067 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0033 | 0.0032 | 0.0032 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0019 | 0.0009 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0079 | 0.0079 |
Brugia malayi | glutathione reductase | 0.0049 | 0.0053 | 0.0053 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.0053 | 0.0043 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0008 |
Mycobacterium tuberculosis | Probable reductase | 0.0111 | 0.0137 | 0.0128 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0036 | 0.0036 |
Trichomonas vaginalis | set domain proteins, putative | 0.0234 | 0.0303 | 0.0753 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0019 | 0.0019 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0039 | 0.0039 | 0.003 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0019 | 0.0009 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0014 | 0.0006 | 0.0015 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0019 | 0.0009 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2895 | 0.3897 | 0.9984 |
Schistosoma mansoni | smad | 0.0017 | 0.001 | 0.001 |
Leishmania major | cytochrome p450-like protein | 0.0039 | 0.0039 | 0.003 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0017 | 0.001 | 0.0005 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0111 | 0.0137 | 0.0128 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.001 | 0.001 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.0079 | 0.0079 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0027 | 0.0017 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0049 | 0.0053 | 0.0135 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.2895 | 0.3897 | 0.3897 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0019 | 0.0009 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.0026 | 0.0067 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.0013 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0011 | 0.0321 |
Echinococcus multilocularis | lamin | 0.0029 | 0.0026 | 0.0067 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.2899 | 0.3903 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.0079 | 0.2385 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0039 | 0.0039 | 0.003 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0039 | 0.0039 | 0.003 |
Onchocerca volvulus | 0.0029 | 0.0026 | 0.0261 | |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0039 | 0.0039 | 0.003 |
Onchocerca volvulus | 0.0051 | 0.0056 | 0.1309 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.