Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0335 | 0.0481 | 0.6966 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0033 | 0.0008 | 0.002 |
Brugia malayi | glutaminase DH11.1 | 0.0271 | 0.0382 | 0.0382 |
Loa Loa (eye worm) | glutaminase 2 | 0.0271 | 0.0382 | 0.5527 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0041 | 0.0021 | 0.0006 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.6413 | 1 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.0052 | 0.0052 |
Schistosoma mansoni | glutaminase | 0.0271 | 0.0382 | 0.0381 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0335 | 0.0481 | 0.124 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.6413 | 1 | 1 |
Leishmania major | dihydroorotate dehydrogenase | 0.6413 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0041 | 0.0021 | 0.0013 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0661 | 0.0992 | 0.0992 |
Brugia malayi | RNA, U transporter 1 | 0.0079 | 0.0081 | 0.0081 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0005 | 0.0005 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0088 | 0.0094 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.0469 | 0.0691 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0216 | 0.0295 | 0.4265 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0061 | 0.0052 | 0.0134 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.0156 | 0.2253 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0008 | 0.0008 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.2504 | 0.3878 | 0.3878 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0041 | 0.0021 | 0.0006 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.6413 | 1 | 1 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.6413 | 1 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0052 | 0.0755 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0054 | 0.0053 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0005 | 0.0005 |
Echinococcus multilocularis | geminin | 0.0195 | 0.0262 | 0.0676 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0041 | 0.0021 | 0.0013 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0041 | 0.0021 | 0.0006 |
Leishmania major | cytochrome p450-like protein | 0.0041 | 0.0021 | 0.0021 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0005 | 0.0005 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0335 | 0.0481 | 0.124 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2504 | 0.3878 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0661 | 0.0992 | 0.0992 |
Loa Loa (eye worm) | glutaminase | 0.0271 | 0.0382 | 0.5527 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0041 | 0.0021 | 0.0021 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0093 | 0.0102 | 0.0102 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0054 | 0.0053 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.2504 | 0.3878 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0156 | 0.2253 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0005 | 0.0012 |
Echinococcus multilocularis | snurportin 1 | 0.0297 | 0.0422 | 0.1088 |
Onchocerca volvulus | 0.0088 | 0.0094 | 0.1367 | |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0041 | 0.0021 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0156 | 0.2253 |
Onchocerca volvulus | 0.0031 | 0.0005 | 0.0074 | |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0041 | 0.0021 | 0.0013 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0041 | 0.0021 | 0.0006 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0014 | 0.0036 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0297 | 0.0422 | 0.6117 |
Toxoplasma gondii | hypothetical protein | 0.0107 | 0.0124 | 0.0123 |
Echinococcus multilocularis | Protein lozenge | 0.0059 | 0.0049 | 0.0125 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0335 | 0.0481 | 0.124 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0041 | 0.0021 | 0.0013 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0041 | 0.0021 | 0.0006 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0041 | 0.0021 | 0.0006 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0074 | 0.0073 | 0.0188 |
Echinococcus multilocularis | 0.0041 | 0.0021 | 0.0052 | |
Brugia malayi | Inositol-1 | 0.0037 | 0.0014 | 0.0014 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0014 | 0.0014 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0005 | 0.0005 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.6413 | 1 | 1 |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.6413 | 1 | 1 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.6413 | 1 | 1 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.6413 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.6413 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0041 | 0.0021 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0008 | 0.0119 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0041 | 0.0021 | 0.0013 |
Trypanosoma brucei | glucosidase, putative | 0.0074 | 0.0073 | 0.0073 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0054 | 0.0137 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0005 | 0.0005 |
Brugia malayi | Cytochrome P450 family protein | 0.0122 | 0.0147 | 0.0147 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0041 | 0.0021 | 0.0021 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.0052 | 0.0052 |
Trypanosoma brucei | cytochrome P450, putative | 0.0059 | 0.005 | 0.005 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.2504 | 0.3878 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0054 | 0.0053 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0041 | 0.0021 | 0.0013 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0074 | 0.0073 | 0.0188 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0093 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0122 | 0.0147 | 0.2129 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0005 | 0.0005 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0014 | 0.0036 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.6413 | 1 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0041 | 0.0021 | 0.0013 |
Echinococcus granulosus | geminin | 0.0195 | 0.0262 | 0.0676 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0041 | 0.0021 | 0.0006 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0074 | 0.0073 | 0.0073 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0041 | 0.0021 | 0.0006 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0088 | 0.0094 | 0.0094 |
Schistosoma mansoni | cytochrome P450 | 0.0041 | 0.0021 | 0.002 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0061 | 0.0052 | 0.0134 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0335 | 0.0481 | 0.0481 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0061 | 0.0052 | 0.0134 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.2504 | 0.3878 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0041 | 0.0021 | 0.0013 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0005 | 0.0012 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2504 | 0.3878 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0059 | 0.005 | 0.0036 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0041 | 0.0021 | 0.0013 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.0262 | 0.0262 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0054 | 0.0137 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0041 | 0.0021 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0094 | 0.1367 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0038 | 0.0016 | 0.0016 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0054 | 0.0054 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0041 | 0.0021 | 0.0006 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0014 | 0.0014 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0041 | 0.0021 | 0.0006 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0033 | 0.0008 | 0.002 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.0156 | 0.2253 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0038 | 0.0016 | 0.0016 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0014 | 0.0036 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0661 | 0.0992 | 0.0992 |
Schistosoma mansoni | lozenge | 0.0059 | 0.0049 | 0.0048 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.2504 | 0.3878 | 1 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0041 | 0.0021 | 0.0006 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0014 | 0.0036 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0041 | 0.0021 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0005 | 0.0074 |
Leishmania major | cytochrome p450-like protein | 0.0041 | 0.0021 | 0.0021 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0041 | 0.0021 | 0.0021 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0074 | 0.0073 | 0.0188 |
Brugia malayi | Cytochrome P450 family protein | 0.0041 | 0.0021 | 0.0021 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.6413 | 1 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0216 | 0.0295 | 0.0295 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0014 | 0.0036 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0313 | 0.0446 | 0.0446 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0074 | 0.0073 | 0.0188 |
Schistosoma mansoni | jumonji domain containing protein | 0.0061 | 0.0052 | 0.0052 |
Onchocerca volvulus | 0.0194 | 0.026 | 0.3764 | |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0088 | 0.0094 | 0.0243 |
Mycobacterium leprae | putative cytochrome p450 | 0.0041 | 0.0021 | 0.0013 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0014 | 0.0014 |
Schistosoma mansoni | alpha glucosidase | 0.0074 | 0.0073 | 0.0073 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0074 | 0.0073 | 0.0188 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0313 | 0.0446 | 0.0446 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0074 | 0.0073 | 0.0073 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0313 | 0.0446 | 0.0446 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0093 | 0.0102 | 0.0102 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0035 | 0.0011 | 0.0011 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0041 | 0.0021 | 0.0021 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.2504 | 0.3878 | 0.3878 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0093 | 0.0102 | 0.0102 |
Leishmania major | cytochrome p450-like protein | 0.0059 | 0.005 | 0.005 |
Loa Loa (eye worm) | cytochrome P450 | 0.0041 | 0.0021 | 0.0298 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.2504 | 0.3878 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0014 | 0.0014 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0003 | 0.0008 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0041 | 0.0021 | 0.0013 |
Brugia malayi | Cytochrome P450 family protein | 0.0059 | 0.005 | 0.005 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.0052 | 0.0052 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0041 | 0.0021 | 0.0013 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0059 | 0.005 | 0.0718 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0074 | 0.0073 | 0.1057 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0059 | 0.005 | 0.005 |
Trichomonas vaginalis | set domain proteins, putative | 0.0246 | 0.0341 | 0.088 |
Onchocerca volvulus | 0.0246 | 0.0341 | 0.4941 | |
Onchocerca volvulus | 0.0469 | 0.0691 | 1 | |
Schistosoma mansoni | alpha-glucosidase | 0.0288 | 0.0408 | 0.0408 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0005 | 0.0012 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2504 | 0.3878 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0074 | 0.0073 | 0.0188 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0041 | 0.0021 | 0.0013 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0061 | 0.0052 | 0.0134 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0041 | 0.0021 | 0.0006 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0035 | 0.0011 | 0.0029 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.0052 | 0.0052 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0041 | 0.0021 | 0.0013 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2504 | 0.3878 | 1 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0041 | 0.0021 | 0.0006 |
Schistosoma mansoni | alpha-glucosidase | 0.0288 | 0.0408 | 0.0408 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0008 | 0.0008 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0032 | 0.0032 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0661 | 0.0992 | 0.0992 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0041 | 0.0021 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0469 | 0.0691 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0032 | 0.0465 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0059 | 0.005 | 0.0718 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0014 | 0.0014 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0054 | 0.0039 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.6413 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0041 | 0.0021 | 0.0006 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0041 | 0.0021 | 0.0013 |
Trichomonas vaginalis | glutaminase, putative | 0.0271 | 0.0382 | 0.0984 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0014 | 0.0204 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0041 | 0.0021 | 0.0013 |
Mycobacterium ulcerans | hypothetical protein | 0.0348 | 0.0502 | 0.0488 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0014 | 0.0014 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0041 | 0.0021 | 0.0006 |
Brugia malayi | cytochrome P450 | 0.0041 | 0.0021 | 0.0021 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0041 | 0.0021 | 0.0006 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0041 | 0.0021 | 0.0052 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0041 | 0.0021 | 0.0013 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0073 | 0.0073 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0074 | 0.0073 | 0.0188 |
Echinococcus granulosus | snurportin 1 | 0.0297 | 0.0422 | 0.1088 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0035 | 0.0011 | 0.0165 |
Mycobacterium ulcerans | glutaminase | 0.0271 | 0.0382 | 0.0368 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0032 | 0.0465 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0059 | 0.005 | 0.005 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0041 | 0.0021 | 0.0006 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0073 | 0.0073 |
Brugia malayi | hypothetical protein | 0.0469 | 0.0691 | 0.0691 |
Brugia malayi | Cytochrome P450 family protein | 0.0059 | 0.005 | 0.005 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0074 | 0.0073 | 0.0188 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.0054 | 0.0045 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0014 | 0.0014 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0088 | 0.0094 | 0.0094 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0113 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0059 | 0.005 | 0.0718 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0041 | 0.0021 | 0.0013 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.6413 | 1 | 1 |
Loa Loa (eye worm) | runx1 | 0.0059 | 0.0049 | 0.0706 |
Schistosoma mansoni | hypothetical protein | 0.0297 | 0.0422 | 0.0422 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0004 | 0.0061 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0348 | 0.0502 | 0.0494 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0041 | 0.0021 | 0.0006 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.0262 | 0.0262 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2504 | 0.3878 | 1 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0041 | 0.0021 | 0.0006 |
Brugia malayi | hypothetical protein | 0.0127 | 0.0156 | 0.0156 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.2504 | 0.3878 | 1 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0041 | 0.0021 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0021 | 0.002 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0074 | 0.0073 | 0.0188 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0074 | 0.0073 | 0.0073 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0054 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0 | 0.0004 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0074 | 0.0073 | 0.0188 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0074 | 0.0073 | 0.0188 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0054 | 0.0039 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0074 | 0.0073 | 0.0188 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0035 | 0.0011 | 0.0029 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0074 | 0.0073 | 0.0188 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0041 | 0.0021 | 0.0006 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0032 | 0.0032 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0014 | 0.0036 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.