Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0001 | 0.0029 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.003 | 0.003 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0061 | 0.0067 | 0.0126 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0081 | 0.0102 | 0.0074 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0061 | 0.0067 | 0.0039 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0073 | 0.0044 |
Loa Loa (eye worm) | glutaminase 2 | 0.0309 | 0.0497 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0029 | 0.0026 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0059 | 0.0065 | 0.0036 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0041 | 0.0033 | 0.0004 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0029 | 0.0577 |
Schistosoma mansoni | cytochrome P450 | 0.0041 | 0.0033 | 0.0033 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0029 | 0.0029 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0041 | 0.0033 | 0.0004 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0041 | 0.0033 | 0.0004 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0041 | 0.0033 | 0.0004 |
Echinococcus granulosus | RUN | 0.0022 | 0.0001 | 0.0004 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0059 | 0.0065 | 0.0036 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0029 | 0.0029 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0061 | 0.0067 | 0.0039 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0041 | 0.0033 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0029 | 0.0577 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0061 | 0.0067 | 0.0174 |
Echinococcus granulosus | GPCR family 2 | 0.0051 | 0.005 | 0.0129 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.0076 | 0.1531 |
Echinococcus multilocularis | 0.0041 | 0.0033 | 0.0084 | |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.5804 | 1 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0022 | 0.0001 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.0109 | 0.0151 | 0.0151 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0051 | 0.005 | 0.1007 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0041 | 0.0033 | 0.0004 |
Brugia malayi | hypothetical protein | 0.0248 | 0.0391 | 0.0391 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0081 | 0.0102 | 0.0074 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.0076 | 0.0196 |
Leishmania major | cytochrome p450-like protein | 0.0041 | 0.0033 | 0.0004 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0121 | 0.0171 | 0.3452 |
Schistosoma mansoni | ap endonuclease | 0.0061 | 0.0067 | 0.0067 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0029 | 0.0029 |
Schistosoma mansoni | survival motor neuron protein | 0.0051 | 0.005 | 0.005 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.2266 | 0.3882 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0029 | 0.0026 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0041 | 0.0033 | 0.0004 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0061 | 0.0067 | 0.5 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0061 | 0.0067 | 0.0039 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0081 | 0.0102 | 0.0074 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0041 | 0.0033 | 0.0004 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0029 | 0.0029 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0029 | 0.0026 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0041 | 0.0033 | 0.0004 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2266 | 0.3882 | 1 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0041 | 0.0033 | 0.0004 |
Brugia malayi | Doublecortin family protein | 0.0022 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | inositol-1 | 0.0081 | 0.0102 | 0.2054 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0038 | 0.0028 | 0.0028 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0041 | 0.0033 | 0.0004 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0035 | 0.0023 | 0.0059 |
Mycobacterium ulcerans | glutaminase | 0.0309 | 0.0497 | 0.0469 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2266 | 0.3882 | 1 |
Loa Loa (eye worm) | cytochrome P450 | 0.0041 | 0.0033 | 0.066 |
Onchocerca volvulus | 0.0038 | 0.0029 | 0.5718 | |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0022 | 0.0001 | 0.0004 |
Onchocerca volvulus | 0.0051 | 0.005 | 1 | |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0041 | 0.0033 | 0.0004 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0064 | 0.0073 | 0.0187 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.005 | 0.005 |
Leishmania major | cytochrome p450-like protein | 0.0059 | 0.0065 | 0.0036 |
Schistosoma mansoni | inositol monophosphatase | 0.0081 | 0.0102 | 0.0102 |
Schistosoma mansoni | inositol monophosphatase | 0.0081 | 0.0102 | 0.0102 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0081 | 0.0102 | 0.0216 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0029 | 0.0026 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0061 | 0.0067 | 0.0039 |
Brugia malayi | hypothetical protein | 0.0039 | 0.003 | 0.003 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.2266 | 0.3882 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0022 | 0.0001 | 0.0001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0076 | 0.0076 |
Schistosoma mansoni | polycystin 1-related | 0.0022 | 0.0001 | 0.0001 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0038 | 0.0028 | 0.0028 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0081 | 0.0102 | 0.0035 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0041 | 0.0033 | 0.0084 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0041 | 0.0033 | 0.0004 |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.5804 | 1 | 1 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.5804 | 1 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0029 | 0.0577 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0061 | 0.0067 | 0.0066 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0061 | 0.0067 | 0.0039 |
Echinococcus multilocularis | GPCR, family 2 | 0.0051 | 0.005 | 0.0129 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0041 | 0.0033 | 0.0004 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0041 | 0.0033 | 0.0004 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0029 | 0.0074 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0041 | 0.0033 | 0.0004 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.003 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0029 | 0.0577 |
Onchocerca volvulus | 0.0038 | 0.0029 | 0.5718 | |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0022 | 0.0001 | 0.0004 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0059 | 0.0065 | 0.1301 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0059 | 0.0065 | 0.1301 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.003 | 0.003 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.2266 | 0.3882 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0041 | 0.0033 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.005 | 0.005 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0061 | 0.0067 | 0.0067 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0081 | 0.0102 | 0.0074 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0041 | 0.0033 | 0.0004 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0081 | 0.0102 | 0.0263 |
Brugia malayi | glutaminase DH11.1 | 0.0309 | 0.0497 | 0.0497 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0029 | 0.0027 |
Onchocerca volvulus | 0.0022 | 0.0001 | 0.0288 | |
Brugia malayi | Cytochrome P450 family protein | 0.0041 | 0.0033 | 0.0033 |
Trypanosoma brucei | cytochrome P450, putative | 0.0059 | 0.0065 | 0.0036 |
Brugia malayi | Cytochrome P450 family protein | 0.0059 | 0.0065 | 0.0065 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0248 | 0.0391 | 0.1008 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0081 | 0.0102 | 0.0216 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0041 | 0.0033 | 0.0004 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0081 | 0.0102 | 0.0074 |
Echinococcus multilocularis | RUN | 0.0022 | 0.0001 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0029 | 0.0577 |
Brugia malayi | cytochrome P450 | 0.0041 | 0.0033 | 0.0033 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0041 | 0.0033 | 0.0004 |
Brugia malayi | Inositol-1 | 0.0081 | 0.0102 | 0.0102 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.005 | 0.0129 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0063 | 0.0071 | 0.0183 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0041 | 0.0033 | 0.0004 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0041 | 0.0033 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0029 | 0.0577 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0041 | 0.0033 | 0.0004 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0035 | 0.0023 | 0.0059 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0041 | 0.0033 | 0.0004 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.2266 | 0.3882 | 0.3882 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0081 | 0.0102 | 0.0263 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0076 | 0.0076 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0041 | 0.0033 | 0.0004 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.2266 | 0.3882 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.0076 | 0.1531 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0041 | 0.0033 | 0.0004 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0064 | 0.0073 | 0.0044 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0029 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0151 | 0.3048 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0041 | 0.0033 | 0.0004 |
Schistosoma mansoni | rab6-interacting | 0.0022 | 0.0001 | 0.0001 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0041 | 0.0033 | 0.0004 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0061 | 0.0067 | 0.0039 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.005 | 0.005 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.005 | 0.005 |
Onchocerca volvulus | 0.0022 | 0.0001 | 0.0288 | |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.5804 | 1 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.005 | 0.0129 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0041 | 0.0033 | 0.0004 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0081 | 0.0102 | 0.0186 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.0391 | 0.7877 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0041 | 0.0033 | 0.0004 |
Mycobacterium leprae | putative cytochrome p450 | 0.0041 | 0.0033 | 0.0004 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0061 | 0.0067 | 0.0174 |
Schistosoma mansoni | ap endonuclease | 0.0061 | 0.0067 | 0.0067 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0063 | 0.0071 | 0.0183 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0073 | 0.0044 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0061 | 0.0067 | 0.0066 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0041 | 0.0033 | 0.0004 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0073 | 0.0073 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0022 | 0.0001 | 0.0004 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2266 | 0.3882 | 1 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0041 | 0.0033 | 0.0004 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2266 | 0.3882 | 1 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0061 | 0.0067 | 0.0096 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.016 | 0.0239 | 0.0239 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0041 | 0.0033 | 0.0004 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.0076 | 0.0196 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.0076 | 0.0076 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0041 | 0.0033 | 0.0004 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0041 | 0.0033 | 0.0004 |
Leishmania major | dihydroorotate dehydrogenase | 0.5804 | 1 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0041 | 0.0033 | 0.0004 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.005 | 0.0129 |
Brugia malayi | Cytochrome P450 family protein | 0.0121 | 0.0171 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0029 | 0.0577 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0064 | 0.0073 | 0.0044 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0072 | 0.0087 | 0.0059 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0061 | 0.0067 | 0.0126 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0051 | 0.005 | 0.005 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0041 | 0.0033 | 0.0004 |
Schistosoma mansoni | glutaminase | 0.0309 | 0.0497 | 0.0497 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0051 | 0.005 | 0.005 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0041 | 0.0033 | 0.0004 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0022 | 0.0001 | 0.0004 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0041 | 0.0033 | 0.0004 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0051 | 0.005 | 0.005 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0248 | 0.0391 | 0.1008 |
Brugia malayi | Cytochrome P450 family protein | 0.0059 | 0.0065 | 0.0065 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0061 | 0.0067 | 0.5 |
Loa Loa (eye worm) | doublecortin family protein | 0.0022 | 0.0001 | 0.0029 |
Brugia malayi | RNA binding protein | 0.0066 | 0.0076 | 0.0076 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.5804 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0041 | 0.0033 | 0.0004 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0041 | 0.0033 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0001 | 0.0029 |
Schistosoma mansoni | lipoxygenase | 0.0063 | 0.0071 | 0.0071 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.0076 | 0.0076 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.5804 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0001 | 0.0001 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.5804 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0041 | 0.0033 | 0.0004 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0041 | 0.0033 | 0.0004 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0076 | 0.0076 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0035 | 0.0023 | 0.0458 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0061 | 0.0067 | 0.1357 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.2266 | 0.3882 | 0.3864 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0033 | 0.0033 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.005 | 0.0129 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0064 | 0.0073 | 0.0187 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.003 | 0.0078 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0001 | 0.0001 |
Toxoplasma gondii | exonuclease III APE | 0.0061 | 0.0067 | 0.0039 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0041 | 0.0033 | 0.0004 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0029 | 0.0026 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.0076 | 0.1531 |
Trichomonas vaginalis | glutaminase, putative | 0.0309 | 0.0497 | 0.1237 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0041 | 0.0033 | 0.0004 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.2266 | 0.3882 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.005 | 0.005 |
Schistosoma mansoni | loxhd1 | 0.0022 | 0.0001 | 0.0001 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.2266 | 0.3882 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0244 | 0.0384 | 0.0357 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0035 | 0.0023 | 0.0023 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.5804 | 1 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.085 | 0.1432 | 0.369 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0073 | 0.0044 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.5804 | 1 | 1 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0022 | 0.0001 | 0.0004 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0064 | 0.0073 | 0.0044 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0072 | 0.0087 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.005 | 0.1007 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.2266 | 0.3882 | 1 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.5804 | 1 | 1 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.5804 | 1 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0029 | 0.0074 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.5804 | 1 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0081 | 0.0102 | 0.0216 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0059 | 0.0065 | 0.1301 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.0239 | 0.4806 |
Onchocerca volvulus | 0.0038 | 0.0029 | 0.5718 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0076 | 0.0076 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0041 | 0.0033 | 0.0004 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.016 | 0.0239 | 0.0239 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0041 | 0.0033 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0029 | 0.0577 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0029 | 0.0029 |
Schistosoma mansoni | rab6-interacting | 0.0022 | 0.0001 | 0.0001 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.5804 | 1 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0081 | 0.0102 | 0.0074 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0041 | 0.0033 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0015 | 0.0298 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.016 | 0.0239 | 0.4806 |
Loa Loa (eye worm) | glutaminase | 0.0309 | 0.0497 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0059 | 0.0065 | 0.0036 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0109 | 0.0151 | 0.0151 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0001 | 0.0001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0076 | 0.0076 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0073 | 0.0073 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.