Detailed information for compound 1153606

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 359.466 | Formula: C19H29N5O2
  • H donors: 0 H acceptors: 2 LogP: 0.66 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)CN1CCc2n(CC1)c(nn2)COCCN(C)C
  • InChi: 1S/C19H29N5O2/c1-22(2)12-13-26-15-19-21-20-18-8-9-23(10-11-24(18)19)14-16-4-6-17(25-3)7-5-16/h4-7H,8-15H2,1-3H3
  • InChiKey: MZDHZQZEIUOGQY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii thioredoxin reductase 0.0037 0.0604 0.0537
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0368 1 1
Schistosoma mansoni DNA polymerase eta 0.0019 0.0085 0.0014
Echinococcus granulosus dna polymerase kappa 0.0019 0.0085 0.0014
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0081 0.0081
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0135 0.3382 0.3335
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0081 0.0081
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.025 0.0181
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0085 0.0014
Mycobacterium tuberculosis Probable reductase 0.0085 0.1962 0.1905
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0081 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0081 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0826 0.076
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0071 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0081 0.0081
Echinococcus granulosus dna polymerase eta 0.0019 0.0085 0.0014
Trypanosoma brucei phosphoglycerate kinase 0.0368 1 1
Trypanosoma brucei trypanothione reductase 0.0037 0.0604 0.0537
Mycobacterium tuberculosis Conserved protein 0.0036 0.0553 0.0485
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0618 0.0551
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.2232 0.2176
Treponema pallidum phosphoglycerate kinase 0.0368 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0081 0.001
Loa Loa (eye worm) hypothetical protein 0.0368 1 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.058 0.0513
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0553 0.0485
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0826 0.0826
Giardia lamblia Rrm3p helicase 0.0107 0.2578 0.2524
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0081 0.001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0553 0.0485
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0368 1 1
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0081 0.0081
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0081 0.001
Mycobacterium ulcerans beta-lactamase 0.0036 0.0553 0.0485
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0036 0.0553 0.0485
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.058 0.0513
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0553 0.0485
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0553 0.0485
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0553 0.0485
Loa Loa (eye worm) hypothetical protein 0.0036 0.0553 0.0485
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0081 0.001
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0081 0.001
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0081 0.001
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0081 0.001
Leishmania major phosphoglycerate kinase B, cytosolic 0.0368 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.058 0.0513
Plasmodium falciparum phosphoglycerate kinase 0.0368 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0826 0.076
Mycobacterium ulcerans hypothetical protein 0.0036 0.0553 0.0485
Brugia malayi follicle stimulating hormone receptor 0.0229 0.6034 0.6034
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0081 0.001
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0368 1 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0553 0.0485
Mycobacterium tuberculosis Probable dehydrogenase 0.0085 0.1962 0.1905
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0085 0.0014
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0081 0.001
Echinococcus multilocularis expressed protein 0.0368 0.9992 0.9992
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.058 0.0513
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0081 0.001
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0553 0.0485
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0081 0.001
Brugia malayi beta-lactamase family protein 0.0036 0.0553 0.0553
Trypanosoma brucei unspecified product 0.0019 0.0085 0.0014
Echinococcus granulosus phosphoglycerate kinase 1 0.0368 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0826 0.076
Loa Loa (eye worm) hypothetical protein 0.0019 0.0081 0.001
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.058 0.0513
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0085 0.0014
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.058 0.0513
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0085 0.0014
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0368 1 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0553 0.0553
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.058 0.0513
Loa Loa (eye worm) hypothetical protein 0.0036 0.0553 0.0485
Loa Loa (eye worm) hypothetical protein 0.0019 0.0081 0.001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0553 0.0485
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0085 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0826 0.076
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0618 0.0551
Entamoeba histolytica phosphoglycerate kinase, putative 0.0368 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.058 0.0513
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0604 0.0537
Giardia lamblia Phosphoglycerate kinase 0.0368 1 1
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0081 0.001
Plasmodium vivax glutathione reductase, putative 0.0037 0.0604 0.0537
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.2232 0.2176
Trypanosoma brucei phosphoglycerate kinase, putative 0.0135 0.3382 0.3335
Leishmania major phosphoglycerate kinase C, glycosomal 0.0368 1 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.025 0.0181
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0604 0.0537
Schistosoma mansoni phosphoglycerate kinase 0.0368 1 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0553 0.0485
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0081 0.001
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0135 0.3382 0.3335
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0085 0.0014
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0081 0.001
Trypanosoma brucei phosphoglycerate kinase 0.0135 0.3382 0.3335
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0081 0.001
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0553 0.0485
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0081 0.001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0085 0.0014
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0368 1 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0085 0.0014
Echinococcus multilocularis phosphoglycerate kinase 1 0.0368 1 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0229 0.6034 0.6006
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0368 1 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.058 0.0513
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.025 0.0181
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0604 0.0537
Echinococcus multilocularis dna polymerase eta 0.0019 0.0085 0.0014
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0081 0.0081
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0085 0.1962 0.1905
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0107 0.2578 0.2524
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0553 0.0485
Entamoeba histolytica hypothetical protein 0.0019 0.0081 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0368 1 1
Leishmania major trypanothione reductase 0.0037 0.0604 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0081 0.001
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.599 0.5961
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0107 0.2578 0.2524
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0081 0.001
Brugia malayi hypothetical protein 0.0019 0.0081 0.0081
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0081 0.001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0085 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0553 0.0485
Echinococcus granulosus expressed protein 0.0368 0.9992 0.9992
Leishmania major hypothetical protein, conserved 0.0025 0.025 0.0181
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0107 0.2578 0.2524
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0085 0.1962 0.1905
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0081 0.001
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0107 0.2578 0.2524
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0553 0.0485
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0826 0.076
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0081 0.001
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0553 0.0485
Loa Loa (eye worm) hypothetical protein 0.0025 0.025 0.0181
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0107 0.2578 0.2524
Loa Loa (eye worm) beta-lactamase 0.0036 0.0553 0.0485
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0081 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Leishmania major hypothetical protein, conserved 0.0036 0.0553 0.0485
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0085 0.1962 0.1905
Plasmodium vivax phosphoglycerate kinase, putative 0.0368 1 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.058 0.058
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0368 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0081 0.001
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.058 0.0513
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0085 0.1962 0.1905
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0081 0.001
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.2232 0.1777
Loa Loa (eye worm) hypothetical protein 0.0036 0.058 0.0513
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.058 0.0513
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0081 0.001
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0081 0.001
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0081 0.001
Onchocerca volvulus 0.0036 0.0553 0.5
Giardia lamblia DINP protein human, muc B family 0.0019 0.0085 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.058 0.0513
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.058 0.0513
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0081 0.001
Loa Loa (eye worm) glutathione reductase 0.0037 0.0604 0.0537
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0107 0.2578 0.2524
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0085 0.0014
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0085 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0085 0.1962 0.1492
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0081 0.001
Brugia malayi Phosphoglycerate kinase 0.0135 0.3382 0.3382
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.025 0.0181
Plasmodium falciparum thioredoxin reductase 0.0037 0.0604 0.0537
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.058 0.0513
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0085 0.0014
Mycobacterium tuberculosis Conserved protein 0.0036 0.0553 0.0485
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0553 0.0485
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0081 0.001
Entamoeba histolytica hypothetical protein, conserved 0.0107 0.2578 0.2524
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0081 0.001
Entamoeba histolytica hypothetical protein 0.0019 0.0081 0.001
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0553 0.0485
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0553 0.0485
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0085 0.0014
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0085 0.0014
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0553 0.0485
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0553 0.0485
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.058 0.0513
Toxoplasma gondii ABC1 family protein 0.0036 0.0553 0.0485
Loa Loa (eye worm) hypothetical protein 0.0036 0.0553 0.0485
Mycobacterium ulcerans lipase LipD 0.0036 0.0553 0.0485
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0085 0.0014
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0081 0.001
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0604 0.0537
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0135 0.3382 0.3335
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0081 0.001
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0368 1 1
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0081 0.001
Brugia malayi hypothetical protein 0.0019 0.0081 0.0081
Schistosoma mansoni hypothetical protein 0.0107 0.2578 0.2524
Brugia malayi glutathione reductase 0.0037 0.0604 0.0604
Entamoeba histolytica DNA repair and recombination protein, putative 0.0107 0.2578 0.2524
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.2232 0.2176
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0553 0.0485
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0081 0.001
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.025 0.0181
Schistosoma mansoni phosphoglycerate kinase 0.0368 1 1
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0553 0.0485
Brugia malayi PXA domain containing protein 0.0019 0.0081 0.0081
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0107 0.2578 0.2524
Leishmania major DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Trypanosoma brucei phosphoglycerate kinase 0.0368 1 1
Brugia malayi PXA domain containing protein 0.0019 0.0081 0.0081
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0826 0.076
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.058 0.0513
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0085 0.0014
Onchocerca volvulus 0.0036 0.0553 0.5
Loa Loa (eye worm) hypothetical protein 0.0019 0.0081 0.001
Onchocerca volvulus 0.0036 0.0553 0.5
Loa Loa (eye worm) hypothetical protein 0.0019 0.0081 0.001
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0107 0.2578 0.2524
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0135 0.3382 0.3335
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0081 0.001
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0553 0.0485
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0826 0.076
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0081 0.0081
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0085 0.0014
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0081 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0081 0.001
Brugia malayi beta-lactamase 0.0036 0.0553 0.0553
Leishmania major DNA polymerase eta, putative 0.0019 0.0085 0.0014
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0081 0.001
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0135 0.3382 0.3335
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.2578 0.2524
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0081 0.001
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0553 0.0485
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0081 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0081 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0081 0.001
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0085 0.0085
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.025 0.0181
Brugia malayi beta-lactamase family protein 0.0036 0.0553 0.0553
Loa Loa (eye worm) hypothetical protein 0.0036 0.0553 0.0485
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0553 0.0485
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.058 0.0513
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.025 0.0181
Chlamydia trachomatis phosphoglycerate kinase 0.0368 1 0.5
Trichomonas vaginalis esterase, putative 0.0036 0.0553 0.0485
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0081 0.001
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0085 0.0014
Brugia malayi Thioredoxin reductase 0.0037 0.0604 0.0604
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0081 0.001
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0553 0.0485
Brugia malayi hypothetical protein 0.0025 0.025 0.025
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0085 0.0014
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0107 0.2578 0.2524
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0135 0.3382 0.3335
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0014
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0085 0.0014
Plasmodium falciparum glutathione reductase 0.0037 0.0604 0.0537
Entamoeba histolytica hypothetical protein 0.0019 0.0081 0.001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0826 0.076
Mycobacterium ulcerans phosphoglycerate kinase 0.0368 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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